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Luke Sebastian

Dana-Farber Cancer Institute
H指数:6
被引数:463

个人简介

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教育背景

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工作经历

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荣誉奖项

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Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST

谷胱甘肽硫转移酶通过直接激活MPST来调控线粒体功能和运动表现。

CELL METABOLISM
IF30.9
2025-02-010
PRE
Sprenger, Hans-Georg; Mittenbuhler, Melanie J.; Sun, Yizhi; Van Vranken, Jonathan G.; Schindler, Sebastian; Jayaraj, Abhilash; Khetarpal, Sumeet A.; Smythers, Amanda L.; Vargas-Castillo, Ariana; Puszynska, Anna M.; Spinelli, Jessica B.; Armani, Andrea; Kunchok, Tenzin; Ryback, Birgitta; Seo, Hyuk-Soo; Song, Kijun; Sebastian, Luke; O'Young, Coby; Braithwaite, Chelsea; Dhe-Paganon, Sirano; Burger, Nils; Mills, Evanna L.; Gygi, Steven P.; Paulo, Joao A.; Arthanari, Haribabu; Chouchani, Edward T.; Sabatini, David M.; Spiegelman, Bruce M.
BAD BH3 Helices BCL-2 Mutants That Cause Venetoclax Resistance

BAD BH3螺旋BCL-2突变体导致Venetoclax耐药性

BLOOD
IF23.1
2024-11-050
PRE
Deangelo, Thomas M.; Adhikary, Utsarga; Korshavn, Kyle J.; Brotzen-Smith, Clara R.; Seo, Hyuk-Soo; Song, Kijun; Sebastian, Luke; Dhe-Paganon, Sirano; Wales, Thomas E.; Bird, Gregory H.; Walensky, Loren D.
Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90a

Irisin通过其整合素受体在涉及细胞外Hsp90a的两步过程中发挥作用

MOLECULAR CELL
IF16.6
2023-06-0119
OAAI
Mu, A.; Wales, Thomas E.; Zhou, Haixia; Draga-Coleta, Sorin-Valeriu; Gorgulla, Christoph; Blackmore, Katherine A.; Mittenbuhler, Melanie J.; Kim, Caroline R.; Bogoslavski, Dina; Zhang, Qiuyang; Wang, Zi-Fu; Jedrychowski, Mark P.; Seo, Hyuk-Soo; Song, Kijun; Xu, Andrew Z.; Sebastian, Luke; Gygi, Steven P.; Arthanari, Haribabu; Dhe-Paganon, Sirano; Griffin, Patrick R.; Engen, John R.; Spiegelman, Bruce M.
Lactate regulates cell cycle by remodelling the anaphase promoting complex

乳酸通过重塑后期促进复合物来调节细胞周期

Nature
IF48.5
2023-03-150
PRE
Weihai Liu; Yun Wang; Luiz H. M. Bozi; Patrick D. Fischer; Mark P. Jedrychowski; Haopeng Xiao; Tao Wu; Narek Darabedian; Xiadi He; Evanna L. Mills; Nils Burger; Sanghee Shin; Anita Reddy; Hans-Georg Sprenger; Nhien Tran; Sally Winther; Stephen M. Hinshaw; Jingnan Shen; Hyuk-Soo Seo; Kijun Song; Andrew Z. Xu; Luke Sebastian; Jean J. Zhao; Sirano Dhe-Paganon; Jianwei Che; Steven P. Gygi; Haribabu Arthanari; Edward T. Chouchani
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease

肠道微生物代谢5-ASA降低其在炎症性肠病中的临床疗效

NATURE MEDICINE
IF50
2023-02-2360
OA
Mehta, Raaj S.; Mayers, Jared R.; Zhang, Yancong; Bhosle, Amrisha; Glasser, Nathaniel R.; Nguyen, Long H.; Ma, Wenjie; Bae, Sena; Branck, Tobyn; Song, Kijun; Sebastian, Luke; Pacheco, Julian Avila; Seo, Hyuk-Soo; Clish, Clary; Dhe-Paganon, Sirano; Ananthakrishnan, Ashwin N.; Franzosa, Eric A.; Balskus, Emily P.; Chan, Andrew T.; Huttenhower, Curtis

研究方向

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S
Sirano Dhe‐Paganon
H 指数:61论文数:330被引数:1.4万
H
Hyuk‐Soo Seo
H 指数:37论文数:158被引数:4,706
K
Kijun Song
H 指数:12论文数:44被引数:830
S
Steven P. Gygi
H 指数:195论文数:1,033被引数:17.0万
H
Haribabu Arthanari
H 指数:42论文数:194被引数:7,261
T
Thomas E. Wales
H 指数:37论文数:159被引数:6,822
E
Evanna L. Mills
H 指数:25论文数:49被引数:9,752
N
Nils Burger
H 指数:20论文数:52被引数:1,680
A
Andrew Z. Xu
H 指数:7论文数:11被引数:485
M
Melanie J. Mittenbühler
H 指数:9论文数:19被引数:724