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Sirano Dhe‐Paganon

Dana-Farber Cancer Institute

61H指数
329论文数
1.4W被引数
收录论文 98
发表时间
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Chemoimmunotherapy-associated CD20 (MS4A1) resistance mutations in Waldenström macroglobulinemia: Epitope disruption independent of expression with implications for CD20-directed cellular therapies华氏巨球蛋白血症中与化疗免疫疗法相关的CD20 (MS4A1) 耐药突变：与表达无关的表位破坏，对CD20靶向细胞疗法的意义
errHemaSphere
IF14.6
err2026-10-01
err0
errOAAI
errAlberto Guijosa; Nickolas Tsakmaklis; Sirano Dhe-Paganon; Filip Garbicz; Ruben Carrasco; John Hatcher; Andres Ramirez-Gamero; Dominic Pizzarella; Amanda Kofides; Shirong Liu; Hao Sun; Xia Liu; María L. Guerrera; Andrew R. Branagan; Gottfried von Keudell; Shayna R. Sarosiek; Jorge J. Castillo; Zachary R. Hunter; Steven P. Treon
err分享
err收藏
AI-enhanced adaptive virtual screening of large libraries for ligand discovery用于配体发现的大型文库的AI增强自适应虚拟筛选
errNature Biotechnology
IF41.7
err2026-09-01
err0
errOAAI
errDomiziana Cecchini; AkshatKumar Nigam; Ming Tang; Joana Reis; Matt Koop; Andrea Gottinger; Callum Robert Nicoll; Yao Wang; Abhilash Jayaraj; Süleyman Selim Çınaroglu˘; Ricarda Törner; Yehor Malets; Minko Gehev; Krishna M. Padmanabha Das; Kelly Churion; Jongwan Kim; Nidhin Thomas; Yong Li; Hyuk-Soo Seo; Sirano Dhe-Paganon; Christopher Secker; Mohammad Haddadnia; Alexander Hasson; Minkai Li; Abhishek Kumar; Roni Levin-Konigsberg; Eun-Bee Choi; Geoffrey I. Shapiro; Huel Cox; Luke Sebastian; Chelsea Braithwaite; Puspalata Bashyal; Dmytro S. Radchenko; Aditya Kumar; Lei Yang; Pierre-Yves Aquilanti; Henry Gabb; Amr Alhossary; Eric O’Neill; Gerhard Wagner; Alán Aspuru-Guzik; Yurii S. Moroz; Charalampos G. Kalodimos; Konstantin Fackeldey; John D. Schuetz; Andrea Mattevi; Haribabu Arthanari; Christoph Gorgulla
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Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myelomaIRF4的药理学靶向作为多发性骨髓瘤的治疗策略
errNature Chemical Biology
IF13.7
err2026-05-28
err0
PREAI
errMichael P. Agius; Chen Song; Qi Liu; Tomoki Iemura; Laura Hevenor; N. Connor Payne; Romanos Sklavenitis Pistofidis; Lorena Pantano; Hongfang Zhao; Hyuk-Soo Seo; Daniel Heilpern-Mallory; Caleb Heaslip; Zhen-Yu J. Sun; Puspalata Bashyal; Michelle P. Aranha; Elizabeth Lightbody; Ralph Mazitschek; Sirano Dhe-Paganon; Constantine S. Mitsiades; Irene M. Ghobrial; Jun Qi
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Zanubrutinib and pirtobrutinib show synergistic killing and suppression of BTK signaling in MYD88-mutated lymphoma cells泽布替尼和匹鲁替尼在MYD88突变淋巴瘤细胞中表现出协同杀伤和抑制BTK信号通路
errBlood Advances
IF7.1
err2026-04-17
err0
errOAAI
errDominic Pizzarella; Amanda Kofides; John M Hatcher; Xia Liu; Alberto Guijosa; Nickolas Tsakmaklis; Abigail L. Peachey; Jinhua Wang; Maria Luisa Guerrera; Christopher J Patterson; Zachary R Hunter; Hao Sun; Shayna R Sarosiek; Jorge J. Castillo; Sara J. Buhrlage; Sirano Dhe-Paganon; Andrew R. Branagan; Steven P. Treon; Shirong Liu
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err收藏
Autopalmitoylation of IDH1-R132H regulates its neomorphic activity in cancer cellsIDH1-R132H的棕榈酰化自调节其在癌细胞中的新生物活性
errNature Chemical Biology
IF13.7
err2026-01-13
err0
PREAI
errLu Hu; Jinyu Lin; Liping Sun; Alison M. Berezuk; Katharine S. Tuttle; Xing Zhu; Hyuk-Soo Seo; Sirano Dhe-Paganon; Pan Li; Yang Sun; Lisheng Ni; Jianan Zhang; Dazhi Tan; Hiroaki Wakimoto; Daniel P. Cahill; Xiaochen Bai; Xuelian Luo; John M. Asara; Sriram Subramaniam; Yibing Shan; Xu Wu
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err收藏
Discovery of a small molecule TLR3 agonist adjuvant小分子TLR3激动剂佐剂的发现
errNature Communications
IF15.7
err2025-12-04
err0
errOAAI
errBranden Lee; Danica Dong; Etsuro Nanishi; John Mark Awad; Kimia Z. Abedi; Yoshine Saito; Francesco Borriello; Soumik Barman; Byron Brook; Aisling Kelly; Manisha Menon; Constance Marques-Mourlet; Maansi V. Gupta; Ida Lister; Chiwoo Oh; Kevin Lyskawa; Morgan Goetz; Kristina Walker; Wing Ki Cheng; Spencer E. Brightman; Pankaj Sharma; Timothy R. O’Meara; Katherine Chew; Daniel Vieira; Kevin Ryff; Cali Sweitzer; Sanya Thomas; Simon D. van Haren; Matthew Pettengill; Hyuk-Soo Seo; Sirano Dhe-Paganon; Wei Zhang; Ofer Levy; David J. Dowling
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Author Correction: Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes作者更正：METTL3 m6A甲基转移酶的氧化还原调控在β细胞中控制1型糖尿病的先天免疫反应
errNature Cell Biology
IF19.1
err2025-11-17
err0
errOAAI
errDario F. De Jesus; Zijie Zhang; Natalie K. Brown; Xiaolu Li; Ling Xiao; Jiang Hu; Matthew J. Gaffrey; Garrett Fogarty; Sevim Kahraman; Jiangbo Wei; Giorgio Basile; Tariq M. Rana; Clayton Mathews; Alvin C. Powers; Audrey V. Parent; Mark A. Atkinson; Sirano Dhe-Paganon; Decio L. Eizirik; Wei-Jun Qian; Chuan He; Rohit N. Kulkarni
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err收藏
Pharmacologic interrogation of USP28 cellular function in p53 signalingUSP28细胞功能在p53信号通路中的药理学研究
errCell Chemical Biology
IF7.2
err2025-09-02
err0
PREAI
errAriana S. Bratt; Susan Kilgas; Maria I. Tarazona Guzman; Robert S. Magin; Isabella Jaen Maisonet; Cara A. Starnbach; Wei Pin Teh; Anthony C. Varca; Bin Hu; Esteban Tarazona Guzman; Hyuk-Soo Seo; Sirano Dhe-Paganon; Nicholas M. Girardi; Guillaume Adelmant; Jarrod A. Marto; Dipanjan Chowdhury; Sara J. Buhrlage
err分享
err收藏
Targeting transcription factors through an IMiD independent zinc finger domain通过IMiD非依赖性锌指域靶向转录因子
errEMBO MOLECULAR MEDICINE
IF8.3
err2025-05-14
err0
errOAAI
errLiu, Bee Hui; Liu, Miao; Radhakrishnan, Sridhar; Dai, Meng-Yuan; Jaladanki, Chaitanya Kumar; Gao, Chong; Tang, Jing Ping; Kumari, Kalpana; Go, Mei Lin; Vu, Kim Anh L.; Kwon, Junsu; Seo, Hyuk-Soo; Song, Kijun; Tian, Xi; Feng, Li; Tan, Justin L.; Melkonian, Arek, V; Liu, Zhaoji; Wulf, Gerburg; Arthanari, Haribabu; Qi, Jun; Dhe-Paganon, Sirano; Clohessy, John G.; Choong, Yeu Khai; Sivaraman, J.; Fan, Hao; Tenen, Daniel G.; Chai, Li
err分享
err收藏
Leveraging relaxation-optimized 1H-13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins利用弛豫优化的1H-13C相关信号在4-19F-苯丙氨酸中的原子探针作用，探究大蛋白的结构与动态特性
errNATURE CHEMISTRY
IF20.2
err2025-05-05
err0
PREAI
errBoeszoermenyi, Andras; Radeva, Denitsa L.; Schindler, Sebastian; Valadares, Veronica; Padmanabha Das, Krishna M.; Dubey, Abhinav; Viennet, Thibault; Schmitt, Max; Kast, Peter; Gelev, Vladimir M.; Stoyanov, Nikolay; Burdzhiev, Nikola; Petrov, Ognyan; Ficarro, Scott; Marto, Jarred; Geffken, Ezekiel A.; Dhe-Paganon, Sirano; Seo, Hyuk-Soo; Alexander, Nathan D.; Cooley, Richard B.; Mehl, Ryan A.; Kovacs, Helena; Anklin, Clemens; Bermel, Wolfgang; Kuprov, Ilya; Takeuchi, Koh; Arthanari, Haribabu
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err收藏
Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST谷胱甘肽硫转移酶通过直接激活MPST来调控线粒体功能和运动表现。
errCELL METABOLISM
IF30.9
err2025-02-01
err0
PREAI
errSprenger, Hans-Georg; Mittenbuhler, Melanie J.; Sun, Yizhi; Van Vranken, Jonathan G.; Schindler, Sebastian; Jayaraj, Abhilash; Khetarpal, Sumeet A.; Smythers, Amanda L.; Vargas-Castillo, Ariana; Puszynska, Anna M.; Spinelli, Jessica B.; Armani, Andrea; Kunchok, Tenzin; Ryback, Birgitta; Seo, Hyuk-Soo; Song, Kijun; Sebastian, Luke; O'Young, Coby; Braithwaite, Chelsea; Dhe-Paganon, Sirano; Burger, Nils; Mills, Evanna L.; Gygi, Steven P.; Paulo, Joao A.; Arthanari, Haribabu; Chouchani, Edward T.; Sabatini, David M.; Spiegelman, Bruce M.
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err收藏
Open-source electrophilic fragment screening platform to identify chemical starting points for UCHL1 covalent inhibitors开源亲电性片段筛选平台，用于识别UCHL1共价抑制剂的化学起始点
errSLAS DISCOVERY
IF2.7
err2024-12-01
err0
errOAAI
errFicarro, Scott B.; Marto, Zachary H.; Girardi, Nicholas M.; Deng, Dingyu; Maisonet, Isabella Jaen; Adelmant, Guillaume; Fleming, Laura E.; Sharafi, Mona; Tavares, Isidoro; Zhao, Andrew; Kim, Hyojeon; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Buhrlage, Sara J.
err分享
err收藏
BAD BH3 Helices BCL-2 Mutants That Cause Venetoclax ResistanceBAD BH3螺旋BCL-2突变体导致Venetoclax耐药性
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errDeangelo, Thomas M.; Adhikary, Utsarga; Korshavn, Kyle J.; Brotzen-Smith, Clara R.; Seo, Hyuk-Soo; Song, Kijun; Sebastian, Luke; Dhe-Paganon, Sirano; Wales, Thomas E.; Bird, Gregory H.; Walensky, Loren D.
err分享
err收藏
Structure-function mapping of DHODH shows deviations in protein structure
errCANCER RESEARCH
IF16.6
err2024-03-22
err1
PREAI
errPokhriyal, Ruchika; Evans, Laura; Seo, Hyuk-Soo; O'Neil, Jillian K.; Rouaisnel, Betty; Kamburov, Atanas; Guenther, Judith; Gradl, Stefan; Arthanari, Haribabu; Christian, Sven; Yang, Xiaoping; Dhe-Paganon, Sirano; Losman, Julie-Aurore
err分享
err收藏
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetesΒ 细胞中m6A甲基转移酶METTL3的氧化还原调节控制1型糖尿病的先天免疫反应
errNATURE CELL BIOLOGY
IF19.1
err2024-02-26
err8
errOAAI
errDe Jesus, Dario F.; Zhang, Zijie; Brown, Natalie K.; Li, Xiaolu; Xiao, Ling; Hu, Jiang; Gaffrey, Matthew J.; Fogarty, Garrett; Kahraman, Sevim; Wei, Jiangbo; Basile, Giorgio; Rana, Tariq M.; Mathews, Clayton; Powers, Alvin C.; Parent, Audrey V.; Atkinson, Mark A.; Dhe-Paganon, Sirano; Eizirik, Decio L.; Qian, Wei-Jun; He, Chuan; Kulkarni, Rohit N.
err分享
err收藏
A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma
errCANCER RESEARCH
IF16.6
err2024-01-17
err1
errOAAI
errHwang, Grace H.; Pazyra-Murphy, Maria F.; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Stopka, Sylwia A.; Dipiazza, Marina; Sutter, Nizhoni; Gero, Thomas W.; Volkert, Alison; Ombelets, Lincoln; Dittemore, Georgia; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Agar, Nathalie Y. R.; Scott, David A.; Segal, Rosalind A.
err分享
err收藏
Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance
errJOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
IF11.2
err2023-11-01
err6
errOAAI
errO'Meara, Timothy R.; Nanishi, Etsuro; Mcgrath, Marisa E.; Barman, Soumik; Dong, Danica; Dillen, Carly; Menon, Manisha; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Ernst, Robert K.; Levy, Ofer; Frieman, Matthew B.; Dowling, David J.
err分享
err收藏
BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMABAF复杂扰动作为H3K27M小儿神经胶质瘤的新治疗机会
errNEURO-ONCOLOGY
IF13.4
err2023-06-12
err0
errOAAI
errPanditharatna, Eshini; Marques, Joana G.; Wang, Tingjian; Trissal, Maria; Liu, Ilon; Jiang, Li; Beck, Alexander; Groves, Andrew; Dharia, Neekesh; Hoffman, Samantha; Kugener, Guillaume; Shaw, McKenzie; Hack, Olivia; Dempster, Joshua; Lareau, Caleb; Quezada, Michael; Stanton, Ann-Catherine; Wyatt, Meghan; Kalani, Zohra; Goodale, Amy; Vazquez, Francisca; Piccioni, Federica; Doench, John; Root, David; Anastas, Jamie; Jones, Kristen; Conway, Amy; Stopka, Sylwia; Regan, Michael; Liang, Yu; Seo, Hyuk-Soo; Song, Kijun; Bashyal, Puspalata; Mathewson, Nathan; Dhe-Paganon, Sirano; Suva, Mario L.; Carcaboso, Angel M.; Lavarino, Cinzia; Mora, Jaume; Nguyen, Quang-De; Ligon, Keith L.; Shi, Yang; Agnihotri, Sameer; Agar, Nathalie Y. R.; Stegmaier, Kimberly; Stiles, Charles D.; Monje, Michelle; Golub, Todd R.; Qi, Jun; Filbin, Mariella G.
err分享
err收藏
Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90aIrisin通过其整合素受体在涉及细胞外Hsp90a的两步过程中发挥作用
errMOLECULAR CELL
IF16.6
err2023-06-01
err19
errOAAI
errMu, A.; Wales, Thomas E.; Zhou, Haixia; Draga-Coleta, Sorin-Valeriu; Gorgulla, Christoph; Blackmore, Katherine A.; Mittenbuhler, Melanie J.; Kim, Caroline R.; Bogoslavski, Dina; Zhang, Qiuyang; Wang, Zi-Fu; Jedrychowski, Mark P.; Seo, Hyuk-Soo; Song, Kijun; Xu, Andrew Z.; Sebastian, Luke; Gygi, Steven P.; Arthanari, Haribabu; Dhe-Paganon, Sirano; Griffin, Patrick R.; Engen, John R.; Spiegelman, Bruce M.
err分享
err收藏
Kinase activation through dimerization by human SH2-B
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err65
errOAAI
errNishi, M; Werner, ED; Oh, BC; Frantz, JD; Dhe-Paganon, S; Hansen, L; Lee, J; Shoelson, SE
err分享
err收藏

研究方向

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合作学者
合作期刊
L
Lewis C. Cantley
H 指数: 214 · 论文数: 1.4K
K
Kenneth C. Anderson
H 指数: 199 · 论文数: 3.1K
S
Steven P. Gygi
H 指数: 195 · 论文数: 1.0K
B
Bruce M. Spiegelman
H 指数: 186 · 论文数: 471
T
Todd R. Golub
H 指数: 176 · 论文数: 749
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