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Z

Zhuoran Yin

Harvard University
H指数:18
被引数:3,215

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Immune checkpoint TIM-3 regulates microglia and Alzheimer's disease

免疫检查点TIM-3调控小胶质细胞和阿尔茨海默病

NATURE
IF48.5
2025-04-090
PRE
Kimura, Kimitoshi; Subramanian, Ayshwarya; Yin, Zhuoran; Khalilnezhad, Ahad; He, Danyang; Dixon, Karen O.; Chitta, Udbhav Kasyap; Ding, Xiaokai; Adhikari, Niraj; Guzchenko, Isabell; Zhang, Xiaoming; Tang, Ruihan; Pertel, Thomas; Myers, Samuel A.; Aastha, Aastha; Eskandari-Sedighi, Ghazaleh; Singh, Vasundhara; Liu, Lei; Lambden, Conner; Kleemann, Kilian L.; Gupta, Neha; Barry, Jen-Li; Durao, Ana; Cheng, Yiran; Silveira, Sebastian; Zhang, Huiyuan; Suhail, Aamir; Delorey, Toni; Rozenblatt-Rosen, Orit; Freeman, Gordon J.; Selkoe, Dennis J.; Weiner, Howard L.; Blurton-Jones, Mathew; Cruchaga, Carlos; Regev, Aviv; Suva, Mario L.; Butovsky, Oleg; Kuchroo, Vijay K.
Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease

性别依赖的APOE4中性粒细胞-小胶质细胞相互作用驱动阿尔茨海默病的认知障碍

NATURE MEDICINE
IF50
2024-07-035
PRE
Rosenzweig, Neta; Kleemann, Kilian L.; Rust, Thomas; Carpenter, Madison; Grucci, Madeline; Aronchik, Michael; Brouwer, Nieske; Valenbreder, Isabel; Cooper-Hohn, Joya; Iyer, Malvika; Krishnan, Rajesh K.; Sivanathan, Kisha N.; Brandao, Wesley; Yahya, Taha; Durao, Ana; Yin, Zhuoran; Chadarevian, Jean Paul; Properzi, Michael J.; Nowarski, Roni; Davtyan, Hayk; Weiner, Howard L.; Blurton-Jones, Mathew; Yang, Hyun-Sik; Eggen, Bart J. L.; Sperling, Reisa A.; Butovsky, Oleg
Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer's disease mouse models

在阿尔茨海默病小鼠模型中，拟杆菌抑制 β-淀粉样蛋白的小胶质细胞清除并促进斑块沉积

NATURE COMMUNICATIONS
IF15.7
2024-05-089
OAAI
Wasen, Caroline; Beauchamp, Leah C.; Vincentini, Julia; Li, Shuqi; Leserve, Danielle S.; Gauthier, Christian; Lopes, Juliana R.; Moreira, Thais G.; Ekwudo, Millicent N.; Yin, Zhuoran; da Silva, Patrick; Krishnan, Rajesh K.; Butovsky, Oleg; Cox, Laura M.; Weiner, Howard L.
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints
NATURE IMMUNOLOGY
IF27.6
2023-09-2551
OA
Yin, Zhuoran; Rosenzweig, Neta; Kleemann, Kilian L.; Zhang, Xiaoming; Brandao, Wesley; Margeta, Milica A.; Schroeder, Caitlin; Sivanathan, Kisha N.; Silveira, Sebastian; Gauthier, Christian; Mallah, Dania; Pitts, Kristen M.; Durao, Ana; Herron, Shawn; Shorey, Hannah; Cheng, Yiran; Barry, Jen-Li; Krishnan, Rajesh K.; Wakelin, Sam; Rhee, Jared; Yung, Anthony; Aronchik, Michael; Wang, Chao; Jain, Nimansha; Bao, Xin; Gerrits, Emma; Brouwer, Nieske; Deik, Amy; Tenen, Daniel G.; Ikezu, Tsuneya; Santander, Nicolas G.; Mckinsey, Gabriel L.; Baufeld, Caroline; Sheppard, Dean; Krasemann, Susanne; Nowarski, Roni; Eggen, Bart J. L.; Clish, Clary; Tanzi, Rudolph E.; Madore, Charlotte; Arnold, Thomas D.; Holtzman, David M.; Butovsky, Oleg
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia

调节小胶质细胞miR-155转录表型通过限制Clec7a/Galectin-3神经退行性小胶质细胞来缓解阿尔茨海默氏症诱导的视网膜血管病变

ACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
2022-09-0819
OAAI
Shi, Haoshen; Yin, Zhuoran; Koronyo, Yosef; Fuchs, Dieu-Trang; Sheyn, Julia; Davis, Miyah R.; Wilson, Jered W.; Margeta, Milica A.; Pitts, Kristen M.; Herron, Shawn; Ikezu, Seiko; Ikezu, Tsuneya; Graham, Stuart L.; Gupta, Vivek K.; Black, Keith L.; Mirzaei, Mehdi; Butovsky, Oleg; Koronyo-Hamaoui, Maya

研究方向

暂未获取到该数据
O
Oleg Butovsky
H 指数:62论文数:161被引数:3.0万
B
Bart J. L. Eggen
H 指数:57论文数:284被引数:1.3万
C
Christian Gauthier
H 指数:12论文数:25被引数:841
C
Charlotte Madore
H 指数:29论文数:62被引数:6,975
N
Nieske Brouwer
H 指数:41论文数:150被引数:6,525
D
Divya Raj
H 指数:12论文数:34被引数:2,844
P
Peter Paul De Deyn
H 指数:102论文数:2,149被引数:4.7万
D
Debby Van Dam
H 指数:44论文数:1,208被引数:6,856
I
Inge R. Holtman
H 指数:27论文数:71被引数:6,711
K
Kristen Pitts
H 指数:7论文数:22被引数:504