未登录 Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results 个体化异源黑猩猩腺病毒和自我扩增mRNA新抗原疫苗治疗晚期转移性实体瘤: 1期试验中期结果 Palmer, Christine D.; Rappaport, Amy R.; Davis, Matthew J.; Hart, Meghan G.; Scallan, Ciaran D.; Hong, Sue-Jean; Gitlin, Leonid; Kraemer, Lauren D.; Kounlavouth, Sonia; Yang, Aaron; Smith, Lindsey; Schenk, Desiree; Skoberne, Mojca; Taquechel, Kiara; Marrali, Martina; Jaroslavsky, Jason R.; Nganje, Charmaine N.; Maloney, Elizabeth; Zhou, Rita; Navarro-Gomez, Daniel; Greene, Adrienne C.; Grotenbreg, Gijsbert; Greer, Renee; Blair, Wade; Cao, Minh Duc; Chan, Shawn; Bae, Kyounghwa; Spira, Alexander I.; Roychowdhury, Sameek; Carbone, David P.; Henick, Brian S.; Drake, Charles G.; Solomon, Benjamin J.; Ahn, Daniel H.; Mahipal, Amit; Maron, Steve B.; Johnson, Benny; Rousseau, Raphael; Yelensky, Roman; Liao, Chih-Yi; Catenacci, Daniel V. T.; Allen, Andrew; Ferguson, Andrew R.; Jooss, Karin 分享 收藏
ACCELERATE-Five years accelerating cancer drug development for children and adolescents Pearson, Andrew D. J.; Weiner, Susan L.; Adamson, Peter C.; Karres, Dominik; Reaman, Gregory; Rousseau, Raphael; Blanc, Patricia; Norga, Koen; Skolnik, Jeffrey; Kearns, Pam; Scobie, Nicole; Barry, Elly; Marshall, Lynley, V; Knox, Leona; Caron, Hubert; Wariabharaj, Darshan; Pappo, Alberto; DuBois, Steven G.; Gore, Lia; Kieran, Mark; Weigel, Brenda; Fox, Elizabeth; Nysom, Karsten; de Rojas, Teresa; Vassal, Gilles 分享 收藏
Clinical outcomes and immune responses in a phase I/II study of personalized, neoantigen-directed immunotherapy in patients with advanced MSS-CRC, GEA and NSCLC Catenacci, D. V.; Liao, C-Y.; Maron, S.; Solomon, B. J.; Mahipal, A.; Johnson, M. L.; Carbone, D.; Henick, B. S.; Johnson, B.; Roychowdhury, S.; Mody, K.; Ahn, D. H.; Bournazou, E.; Schenk, D.; Kounlavouth, S.; Kraemer, L.; Talbot, G.; Rousseau, R.; Ferguson, A. R.; Spira, A. 分享 收藏
Identification of pre-existing neoantigen-specific T cells in patients receiving checkpoint inhibitor therapy using a deep learning antigen prediction model Palmer, Christine D.; Bulik, Brendan; Yang, Aaron; Hart, Meghan; Davis, Matthew; Francis, Joshua; Duke, Fujiko; Zhou, Rita; Busby, Jennifer; Murphy, Tyler; Clark, Andrew; Young, Lauren; Zhong, Mike; Caldwell, Kamilah; Abhyankar, Jesse; Cook, Alison; Boucher, Tommy; Rousseau, Raphael; Voong, Cynthia; Rizvi, Naiyer; Frattini, Mark; Yelensky, Roman; Jooss, Karin; Skoberne, Mojca 分享 收藏
Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification Bulik-Sullivan, Brendan; Busby, Jennifer; Palmer, Christine D.; Davis, Matthew J.; Murphy, Tyler; Clark, Andrew; Busby, Michele; Duke, Fujiko; Yang, Aaron; Young, Lauren; Ojo, Noelle C.; Caldwell, Kamilah; Abhyankar, Jesse; Boucher, Thomas; Hart, Meghan G.; Makarov, Vladimir; De Montpreville, Vincent Thomas; Mercier, Olaf; Chan, Timothy A.; Scagliotti, Giorgio; Bironzo, Paolo; Novello, Silvia; Karachaliou, Niki; Rosell, Rafael; Anderson, Ian; Gabrail, Nashat; Hrom, John; Limvarapuss, Chainarong; Choquette, Karin; Spira, Alexander; Rousseau, Raphael; Voong, Cynthia; Rizvi, Naiyer A.; Fadel, Elie; Frattini, Mark; Jooss, Karin; Skoberne, Mojca; Francis, Joshua; Yelensky, Roman 分享 收藏
Joint adolescent-adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform-ACCELERATE Gaspar, N.; Marshall, L. V.; Binner, D.; Herold, R.; Rousseau, R.; Blanc, P.; Capdeville, R.; Carleer, J.; Copland, C.; Kerloeguen, Y.; Norga, K.; Pacaud, L.; Sevaux, M-A; Spadoni, C.; Sterba, J.; Ligas, F.; Taube, T.; Uttenreuther-Fischer, M.; Chioato, S.; O'Connell, M. A.; Geoerger, B.; Blay, J. -Y.; Soria, J. C.; Kaye, S.; Wulff, B.; Brugieres, L.; Vassal, G.; Pearson, A. D. J. 分享 收藏
Vaccination to improve the persistence of CD19CAR gene-modified T cells in relapsed pediatric acute lymphoblastic leukemia Rossig, C.; Pule, M.; Altvater, B.; Saiagh, S.; Wright, G.; Ghorashian, S.; Clifton-Hadley, L.; Champion, K.; Sattar, Z.; Popova, B.; Hackshaw, A.; Smith, P.; Roberts, T.; Biagi, E.; Dreno, B.; Rousseau, R.; Kailayangiri, S.; Ahlmann, M.; Hough, R.; Kremens, B.; Sauer, M. G.; Veys, P.; Goulden, N.; Cummins, M.; Amrolia, P. J. 分享 收藏
Implementation of mechanism of action biology-driven early drug development for children with cancer Pearson, Andrew D. J.; Herold, Ralf; Rousseau, Raphael; Copland, Chris; Bradley-Garelik, Brigid; Binner, Debbie; Capdeville, Renaud; Caron, Hubert; Carleer, Jacqueline; Chesler, Louis; Geoerger, Birgit; Kearns, Pamela; Marshall, Lynley V.; Pfister, Stefan M.; Schleiermacher, Gudrun; Skolnik, Jeffrey; Spadoni, Cesare; Sterba, Jaroslav; van den Berg, Hendrick; Uttenreuther-Fischer, Martina; Witt, Olaf; Norga, Koen; Vassal, Gilles 分享 收藏
Creating a unique, multi-stakeholder Paediatric Oncology Platform to improve drug development for children and adolescents with cancer Vassal, Gilles; Rousseau, Raphael; Blanc, Patricia; Moreno, Lucas; Bode, Gerlind; Schwoch, Stefan; Schrappe, Martin; Skolnik, Jeffrey; Bergman, Lothar; Bradley-Garelik, Mary Brigid; Saha, Vaskar; Pearson, Andy; Zwierzina, Heinz 分享 收藏
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Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma Chen, L.; Zhao, Y.; Halliday, G. C.; Berry, P.; Rousseau, R. F.; Middleton, S. A.; Nichols, G. L.; Del Bello, F.; Piergentili, A.; Newell, D. R.; Lunec, J.; Tweddle, D. A. 分享 收藏
In Vitro Comparison of Three Different Chimeric Receptor-modified Effector T-cell Populations for Leukemia Cell Therapy Pizzitola, Irene; Agostoni, Valentina; Cribioli, Elisabetta; Pule, Martin; Rousseau, Raphael; Finney, Helene; Lawson, Alastair; Biondi, Andrea; Biagi, Ettore; Marin, Virna 分享 收藏
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Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis Bouzas-Rodriguez, Jimena; Cabrera, Jorge Ruben; Delloye-Bourgeois, Celine; Ichim, Gabriel; Delcros, Jean-Guy; Raquin, Marie-Anne; Rousseau, Raphael; Combaret, Valerie; Benard, Jean; Tauszig-Delamasure, Servane; Mehlen, Patrick 分享 收藏
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Netrin-1 acts as a survival factor for aggressive neuroblastoma Delloye-Bourgeois, Celine; Fitamant, Julien; Paradisi, Andrea; Cappellen, David; Douc-Rasy, Setha; Raquin, Marie-Anne; Stupack, Dwayne; Nakagawara, Akira; Rousseau, Raphael; Combaret, Valerie; Puisieux, Alain; Valteau-Couanet, Dominique; Benard, Jean; Bernet, Agnes; Mehlen, Patrick 分享 收藏
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