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Adolfo Garcı́a-Ocaña

Arthur Riggs Diabetes and Metabolism Research Institute

54H指数
219论文数
8.9K被引数
收录论文 124
发表时间
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Harmine selectively enhances human beta cell identity markers and function via protein kinase A pathways
errDiabetologia
IF10.2
err2026-09-21
err0
errOAAI
errPeng Wang; Kunal Kumar; Luca Lambertini; Hongtao Liu; Olivia Wood; Shuxuan Chen; Aidan Pillard; Donald K. Scott; Joao A. Paulo; Steven P. Gygi; Susmita Khamrui; Stefan Mueller; Adolfo Garcia-Ocana; Esra Karakose; Michael B. Lazarus; Robert J. DeVita; Andrew F. Stewart
err分享
err收藏
Human pancreatic α-cell heterogeneity and trajectory inference analyses reveal SMOC1 as a β-cell dedifferentiation gene人胰腺α细胞异质性及轨迹推断分析揭示SMOC1为β细胞去分化基因
errNature Communications
IF15.7
err2025-10-07
err0
errOAAI
errRandy B. Kang; Miguel Varela; Eunjin Oh; Jungeun Lee; Tuo Zhang; Esra Karakose; Andrew F. Stewart; Donald K. Scott; Debbie C. Thurmond; Adolfo Garcia-Ocana; Geming Lu
err分享
err收藏
A simple approach of nuclei isolation for single nucleus multiome sequencing单细胞多组学测序中细胞核分离的一种简单方法
errJournal of Molecular and Cellular Cardiology
IF4.7
err2025-08-21
err0
PREAI
errYin Wang; Di Ren; Randy Kang; Kai Zhang; Yunqian Peng; Heather Zhou; Geming Lu; Junjie Guo; Adolfo Garcia-Ocaña; Yingfeng Deng; June-Wha Rhee; Zhao V. Wang
err分享
err收藏
NRF2 deficiency leads to inadequate beta cell adaptation during pregnancy and gestational diabetesNRF2缺陷导致妊娠期间β细胞适应性不足，并引发妊娠期糖尿病。
errREDOX BIOLOGY
IF11.9
err2025-02-01
err1
errOAAI
errHaidery, Fatema; Lambertini, Luca; Tse, Isabelle; Dodda, Sriya; Garcia-Ocana, Adolfo; Scott, Donald K.; Baumel-Alterzon, Sharon
err分享
err收藏
LGR4 is essential for maintaining 3-cell homeostasis through suppression of RANK
errMOLECULAR METABOLISM
IF6.6
err2025-02-01
err0
errOAAI
errFilipowska, Joanna; Cisneros, Zelda; Varghese, Sneha S.; Leon-Rivera, Nancy; Wang, Peng; Kang, Randy; Lu, Geming; Yuan, Yate-Ching; Shih, Hung-Ping; Bhattacharya, Supriyo; Dhawan, Sangeeta; Garcia-Ocana, Adolfo; Kondegowda, Nagesha Guthalu; Vasavada, Rupangi C.
err分享
err收藏
NRF2 Dysregulation in Impairs Beta-Cell Mass Expansion during Pregnancy Leading to Gestational Diabetes
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2024-11-01
err0
PREAI
errBaumel-Alterzon, Sharon; Haidery, Fatema; Lambertini, Luca; Tse, Isabelle; Dodda, Sriya; Scott, Donald K.; Garcia-Ocana, Adolfo
err分享
err收藏
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-07-10
err1
PREAI
errRosselot, Carolina; Li, Yansui; Wang, Peng; Alvarsson, Alexandra; Beliard, Kara; Lu, Geming; Kang, Randy; Li, Rosemary; Liu, Hongtao; Gillespie, Virginia; Tzavaras, Nikolaos; Kumar, Kunal; DeVita, Robert J.; Stewart, Andrew F.; Stanley, Sarah A.; Garcia-Ocana, Adolfo
err分享
err收藏
Enhanced Expression of Zinc Finger Protein 385D Leads to Type 2 Diabetes Phenotype in Human Beta Cells
errDIABETES
IF7.5
err2024-06-14
err0
PREAI
errLu, Geming; Kang, Randy; Varela, Miguel A.; Oh, Eunjin; Thurmond, Debbie C.; Garcia-Ocana, Adolfo
err分享
err收藏
Safety, Tolerability, and Metabolic Effects of Once-Weekly GL0034 (Utreglutide) in Individuals with Obesity-A Multiple Ascending Dose Study
errDIABETES
IF7.5
err2024-06-14
err0
PREAI
errThennati, Rajamannar; Burade, Vinod S.; Natarajan, Muthukumaran; Shahi, Pradeep; Nagaraja, Ravishankara; Agrawal, Sudeep K.; Duvauchelle, Thierry; Garcia-Ocana, Adolfo; Rutter, Guy A.; Pratley, Richard E.; Thorens, Bernard; Vilsboll, Tina
err分享
err收藏
GL0034 (Utreglutide), a Novel GLP-1RA, Increases Liver FGF-21 and Demonstrates Significant Efficacy on Weight Loss, HbA1c, and Triglycerides in db/db Mice
errDIABETES
IF7.5
err2024-06-14
err0
PREAI
errThennati, Rajamannar; Burade, Vinod S.; Natarajan, Muthukumaran; Garcia-Ocana, Adolfo; Rutter, Guy A.; Pratley, Richard E.; Thorens, Bernard; Vilsboll, Tina
err分享
err收藏
Single Nucleus Transcriptome Profiling of Human Islet Cells under Metabolic Stress In Vivo
errDIABETES
IF7.5
err2024-06-14
err0
PREAI
errKang, Randy; Lee, Jungeun; Varela, Miguel A.; Karakose, Esra; Stewart, Andrew F.; Scott, Donald; Garcia-Ocana, Adolfo; Lu, Geming
err分享
err收藏
NRF2 is required for neonatal mouse beta cell growth by maintaining redox balance and promoting mitochondrial biogenesis and function
errDIABETOLOGIA
IF10.2
err2024-01-11
err3
errOAAI
errBaumel-Alterzon, Sharon; Katz, Liora S.; Lambertini, Luca; Tse, Isabelle; Heidery, Fatema; Garcia-Ocana, Adolfo; Scott, Donald K.
err分享
err收藏
Transcriptional activation of the Myc gene by glucose in (3-cells requires a ChREBP-dependent 3-D chromatin interaction between the Myc and Pvt1 genes
errMOLECULAR METABOLISM
IF6.6
err2024-01-01
err2
errOAAI
errKatz, Liora S.; Brill, Gabriel; Wang, Peng; Lambertini, Luca; Zhang, Pili; Haldeman, Jonathan M.; Liu, Hongtao; Newgard, Christopher B.; Stewart, Andrew F.; Garcia-Ocana, Adolfo; Scott, Donald K.
err分享
err收藏
Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variantGIPR信号的时空调控会影响葡萄糖稳态，如对常见GIPR变体的研究中所揭示的那样
errMOLECULAR METABOLISM
IF6.6
err2023-12-01
err2
errOAAI
errYammine, Lucie; Picatoste, Belen; Abdullah, Nazish; Leahey, Rosemary A.; Johnson, Emma F.; Gomez-Banoy, Nicolas; Rosselot, Carolina; Wen, Jennifer; Hossain, Tahmina; Goncalves, Marcus D.; Lo, James C.; Garcia-Ocana, Adolfo; McGraw, Timothy E.
err分享
err收藏
NRF2 Regulates Neonatal β-Cell Mass Expansion
errDIABETES
IF7.5
err2023-06-20
err0
PREAI
errBaumel-Alterzon, Sharon; Katz, Liora S.; Lambertini, Luca; Garcia-Ocana, Adolfo; Scott, Donald
err分享
err收藏
A Single Ascending Dose Study of the Novel GLP-1 Receptor Agonist GL0034 (Utreglutide) in Obese Individuals without Diabetes
errDIABETES
IF7.5
err2023-06-20
err0
PREAI
errThennati, Rajamannar; Burade, Vinod S.; Natarajan, Muthukumaran; Shahi, Pradeep; Nagaraja, Ravishankara; Panchal, Satish T.; Agrawal, Sudeep K.; Jandrain, Bernard; Duvauchelle, Thierry; Garcia-Ocana, Adolfo; Rutter, Guy A.; Pratley, Richard E.; Thorens, Bernard; Vilsboll, Tina
err分享
err收藏
Safety and Tolerability of Once-Weekly GL0034 (Utreglutide) in Healthy Individuals-A Multiple Ascending Dose Study
errDIABETES
IF7.5
err2023-06-20
err0
PREAI
errThennati, Rajamannar; Burade, Vinod S.; Natarajan, Muthukumaran; Shahi, Pradeep; Nagaraja, Ravishankara; Panchal, Satish T.; Agrawal, Sudeep K.; Jandrain, Bernard; Duvauchelle, Thierry; Garcia-Ocana, Adolfo; Rutter, Guy A.; Pratley, Richard E.; Thorens, Bernard; Vilsboll, Tina
err分享
err收藏
Transcriptional Activation of Myc by Glucose Requires Recruitment of ChREBP to the Pvt1 Promoter Regulating Proliferation in β-Cells
errDIABETES
IF7.5
err2023-06-20
err0
PREAI
errKatz, Liora S.; Wang, Peng; Brill, Gabriel; Zhang, Pili; Haldeman, Jonathan; Newgard, Christopher B.; Stewart, Andrew F.; Garcia-Ocana, Adolfo; Scott, Donald
err分享
err收藏
Selected DYRK1A Inhibitors Simultaneously Drive Both Human Beta-Cell Proliferation and Differentiation
errDIABETES
IF7.5
err2023-06-20
err0
PREAI
errWang, Peng; Kumar, Kunal; Liu, Hongtao; Wood, Olivia; Karakose, Esra; Choleva, Lauryn; Lambertini, Luca; Garcia-Ocana, Adolfo; Devita, Robert J.; Stewart, Andrew F.
err分享
err收藏
Myc Activity Is Required for Mitochondrial Function and Glucose-Stimulated Insulin Secretion (GSIS) in Pancreatic ß-Cells
errDIABETES
IF7.5
err2023-06-20
err0
PREAI
errLu, Geming; Kang, Randy; Diaz-Pozo, Pedro; Lee, Jungeun; Li, Mingpei; Victor, M. Victor; Scott, Donald; Garcia-Ocana, Adolfo
err分享
err收藏

研究方向

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合作学者
合作期刊
D
Daniel Levy
H 指数: 230 · 论文数: 1.6K
B
Bruce M. Spiegelman
H 指数: 186 · 论文数: 471
M
Martin G. Larson
H 指数: 184 · 论文数: 839
G
Gerald I. Shulman
H 指数: 183 · 论文数: 821
J
Josef Penninger
H 指数: 174 · 论文数: 1.6K
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