Ana Paula Arruda - Publications, H-index & Citations

Ana Paula Arruda

university of california

27H指数

55论文数

3.5K被引数

收录论文 33

发表时间

Endoplasmic reticulum architecture in liver metabolic regulation 内质网结构在肝脏代谢调节中的作用

Trends in Cell Biology

IF18.1

2026-04-07

OAAI

Leonardo Luis Artico; Sophia Hakam; Güneş Parlakgül; Ana Paula Arruda

CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly CLCC1促进肝中性脂质流和核孔复合物组装

Nature

IF48.5

2026-02-25

OAAI

Alyssa J. Mathiowetz; Emily S. Meymand; Güneş Parlakgül; Niek van Hilten; Emily F. Torres; Leonardo L. Artico; Kirandeep K. Deol; Mike Lange; Stephany P. Pang; Cody E. Doubravsky; Melissa A. Roberts; Danielle M. Jorgens; Reena Zalpuri; Misun Kang; Casadora Boone; Brian W. Parks; Yaohuan Zhang; David W. Morgens; Emily Tso Newman; Yingjiang Zhou; Saswata Talukdar; Michael Grabe; Gregory Ku; Tim P. Levine; Ana Paula Arruda; James A. Olzmann

ER gets out of shape with ageing ER随着年龄的增长而变形

Nature Cell Biology

IF19.1

2026-02-02

PREAI

Kalina Lapenta; Güneş Parlakgül; Ana Paula Arruda

CoQ imbalance drives reverse electron transport to disrupt liver metabolism CoQ失衡驱动逆向电子传递以破坏肝脏代谢

NATURE

IF48.5

2025-05-28

PREAI

Goncalves, Renata L. S.; Wang, Zeqiu Branden; Riveros, Jillian K.; Parlakgul, Gunes; Inouye, Karen E.; Lee, Grace Yankun; Fu, Xiaorong; Saksi, Jani; Rosique, Clement; Hui, Sheng Tony; Coll, Mar; Arruda, Ana Paula; Burgess, Shawn C.; Graupera, Isabel

CaMKIIb Ca2+ptures ER signals to initiate autophagosome biogenesis CaMKIIb 通过捕获 Ca2+ 信号来启动自噬体生物发生。

MOLECULAR CELL

IF16.6

2025-02-01

PREAI

Artico, Leonardo Luis; Arruda, Ana Paula

Sterol O-acyltransferase (SOAT/ACAT) activity is required to form cholesterol crystals in hepatocyte lipid droplets

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2024-08-01

OAAI

Bairos, Jordan A.; Njoku, Uche; Zafar, Maria; Akl, May G.; Li, Lei; Parlakgul, Gunes; Arruda, Ana Paula; Widenmaier, Scott B.

Spatial mapping of hepatic ER and mitochondria architecture reveals zonated remodeling in fasting and obesity

NATURE COMMUNICATIONS

IF15.7

2024-05-10

OAAI

Parlakgul, Gunes; Pang, Song; Artico, Leonardo L.; Min, Nina; Cagampan, Erika; Villa, Reyna; Goncalves, Renata L. S.; Lee, Grace Yankun; Xu, C. Shan; Hotamisligil, Gokhan S.; Arruda, Ana Paula

Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis

EMBO JOURNAL

IF8.3

2024-01-11

OAAI

Chang, Ching-Fang; Gunawan, Amanda L.; Liparulo, Irene; Zushin, Peter-James H.; Vitangcol, Kaitlyn; Timblin, Greg A.; Saijo, Kaoru; Wang, Biao; Parlakgul, Gunes; Arruda, Ana Paula; Stahl, Andreas

Integration of ER protein quality-control mechanisms defines ß cell function and ER architecture

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-01-03

OAAI

Shrestha, Neha; Torres, Mauricio; Zhang, Jason; Lu, You; Haataja, Leena; Reinert, Rachel B.; Knupp, Jeffrey; Chen, Yu-Jie; Parlakgul, Gunes; Arruda, Ana Paula; Tsai, Billy; Arvan, Peter; Qi, Ling

Endoplasmic Reticulum Architecture and Inter-Organelle Communication in Metabolic Health and Disease

cold spring harbor perspectives in medicine

IF8.4

2022-08-08

PREAI

Arruda, Ana Paula; Parlakgul, Gunes

Aberrant Ca2+ signaling by IP3Rs in adipocytes links inflammation to metabolic dysregulation in obesity

SCIENCE SIGNALING

IF6.6

2021-12-14

OAAI

Guney, Ekin; Arruda, Ana Paula; Parlakgul, Gunes; Cagampan, Erika; Min, Nina; Lee, Yankun; Greene, Lily; Tsaousidou, Eva; Inouye, Karen; Han, Myoung Sook; Davis, Roger J.; Hotamisligil, Gokhan S.

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

NATURE MEDICINE

IF50

2018-02-05

150

OAAI

Bartelt, Alexander; Widenmaier, Scott B.; Schlein, Christian; Johann, Kornelia; Goncalves, Renata L. S.; Eguchi, Kosei; Fischer, Alexander W.; Parlakgul, Gunes; Snyder, Nicole A.; Nguyen, Truc B.; Bruns, Oliver T.; Franke, Daniel; Bawendi, Moungi G.; Lynes, Matthew D.; Leiria, Luiz O.; Tseng, Yu-Hua; Inouye, Karen E.; Arruda, Ana Paula; Hotamisligil, Gokhan S.

Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity

ELIFE

IF0

2017-12-15

OAAI

Arruda, Ana Paula; Pers, Benedicte Mengel; Parlakgul, Gunes; Guney, Ekin; Goh, Ted; Cagampan, Erika; Lee, Grace Yankun; Goncalves, Renata L.; Hotamisligil, Gokhan S.

Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins

CELL REPORTS

IF6.9

2017-10-01

OAAI

Charles, Khanichi N.; Li, Min-Dian; Engin, Feyza; Arruda, Ana Paula; Inouye, Karen; Hotamisligil, Gokhan S.

RETRACTION: Chaperone insufficiency links TLR4 signaling to endoplasmic reticulum stress (Retraction of Vol 287, Pg 15580, 2012)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-12-01

OAAI

Coope, Andressa; Milanski, Marciane; Arruda, Ana P.; Ignacio-Souza, Leticia M.; Saad, Mario J.; Anhe, Gabriel F.; Velloso, Licio A.

RETRACTION: Deletion of tumor necrosis factor-α receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis (Retraction of Vol 284, Pg 36213, 2009)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-12-01

OAAI

Romanatto, Talita; Roman, Erika A.; Arruda, Ana P.; Denis, Raphael G.; Solon, Carina; Milanski, Marciane; Moraes, Juliana C.; Bonfleur, Maria L.; Degasperi, Giovanna R.; Picardi, Paty K.; Hirabara, Sandro; Boschero, Antonio C.; Curi, Rui; Velloso, Licio A.

Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes

CELL METABOLISM

IF30.9

2015-09-01

261

OAAI

Arruda, Ana Paula; Hotamisligil, Goekhan S.

Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2015-06-17

OAAI

Fu, Suneng; Yalcin, Abdullah; Lee, Grace Y.; Li, Ping; Fan, Jason; Arruda, Ana Paula; Pers, Benedicte M.; Yilmaz, Mustafa; Eguchi, Kosei; Hotamisligil, Goekhan S.

Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity

NATURE MEDICINE

IF50

2014-11-24

554

OAAI

Arruda, Ana Paula; Pers, Benedicte M.; Parlakguel, Guenes; Gueney, Ekin; Inouye, Karen; Hotamisligil, Goekhan S.

Defective Regulation of the Ubiquitin/Proteasome System in the Hypothalamus of Obese Male Mice

ENDOCRINOLOGY

IF3.3

2014-08-01

OAAI

Ignacio-Souza, Leticia M.; Bombassaro, Bruna; Pascoal, Livia B.; Portovedo, Mariana A.; Razolli, Daniela S.; Coope, Andressa; Victorio, Sheila C.; de Moura, Rodrigo F.; Nascimento, Lucas F.; Arruda, Ana P.; Anhe, Gabriel F.; Milanski, Marciane; Velloso, Licio A.

研究方向