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The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ γ Li, Xuexin; Hernandez, Ivo; Koyuncu, Seda; Haeggblad, Maria; Lidemalm, Louise; Abbas, Anna A.; Bendeguz, Sramko; Goebloes, Aniko; Brautigam, Lars; Lucas, Jose J.; Carreras-Puigvert, Jordi; Huehn, Daniela; Pircs, Karolina; Vilchez, David; Fernandez-Capetillo, Oscar 分享 收藏
PAH deficient pathology in humanized c.1066-11G>A phenylketonuria mice Martinez-Pizarro, Ainhoa; Pico, Sara; Lopez-Marquez, Aristides; Rodriguez-Lopez, Claudia; Montalvo, Elena; Alvarez, Mar; Castro, Margarita; Ramon-Maiques, Santiago; Perez, Belen; Lucas, Jose J.; Richard, Eva; Desviat, Lourdes R. 分享 收藏
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RNA SEQUENCING ANALYSES IN BIPOLAR MULTIPLEX FAMILIES POINT TO NOVEL GENES AND DYSREGULATED PATHWAYS Garcia Ortiz, Ines; Martinez Jimenez, Miriam; Kavanagh, Tomas; Marshall, Lee; Heath, Anne; Lucas Lozano, Jose J.; Schoefield, Peter R.; Mitchell, Philip B.; Cooper, Antony A.; Fullerton, Janice; Toma, Claudio 分享 收藏
CPEB4-CLOCK crosstalk during temporal lobe epilepsy de Diego-Garcia, Laura; Brennan, Gary P.; Auer, Theresa; Menendez-Mendez, Aida; Parras, Alberto; Martin-Gil, Alba; Mitra, Meghma; Olla, Ivana; Villalba-Benito, Leticia; Gil, Beatriz; Alves, Mariana; Lau, Kelvin; Delanty, Norman; Beausang, Alan; Cryan, Jane; Brett, Francesca M.; Farrell, Michael A.; O'Brien, Donncha F.; Mendez, Raul; Carracedo-Rodriguez, Gonzalo; Henshall, David C. C.; Lucas, Jose J.; Engel, Tobias 分享 收藏
Pathogenic Mis-splicing of CPEB4 in Schizophrenia Olla, Ivana; Pardinas, Antonio F.; Parras, Alberto; Hernandez, Ivo H.; Santos-Galindo, Maria; Pico, Sara; Callado, Luis F.; Elorza, Ainara; Rodriguez-Lopez, Claudia; Fernandez-Miranda, Gonzalo; Belloc, Eulalia; Walters, James T. R.; O'Donovan, Michael C.; Mendez, Raul; Toma, Claudio; Meana, J. Javier; Owen, Michael J.; Lucas, Jose J. 分享 收藏
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington's disease (vol 10, 83, 2022) Yu, Dahyun; Zarate, Nicole; White, Angel; Coates, De'jah; Tsai, Wei; Nanclares, Carmen; Cuccu, Francesco; Yue, Johnny S.; Brown, Taylor G.; Mansky, Rachel H.; Jiang, Kevin; Kim, Hyuck; Nichols-Meade, Tessa; Larson, Sarah N.; Gundry, Katherine; Zhang, Ying; Tomas-Zapico, Cristina; Lucas, Jose J.; Benneyworth, Michael; Oz, Gulin; Cvetanovic, Marija; Araque, Alfonso; Gomez-Pastor, Rocio 分享 收藏
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in huntington's disease Yu, Dahyun; Zarate, Nicole; White, Angel; Coates, De'jah; Tsai, Wei; Nanclares, Carmen; Cuccu, Francesco; Yue, Johnny S.; Brown, Taylor G.; Mansky, Rachel H.; Jiang, Kevin; Kim, Hyuck; Nichols-Meade, Tessa; Larson, Sarah N.; Gundry, Katherine; Zhang, Ying; Tomas-Zapico, Cristina; Lucas, Jose J.; Benneyworth, Michael; Oz, Gulin; Cvetanovic, Marija; Araque, Alfonso; Gomez-Pastor, Rocio 分享 收藏
CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease CPEB改变和异常转录组聚腺苷酸化导致亨廷顿氏病可治疗的SLC19A3缺乏症 Pico, Sara; Parras, Alberto; Santos-Galindo, Maria; Pose-Utrilla, Julia; Castro, Margarita; Fraga, Enrique; Hernandez, Ivo H.; Elorza, Ainara; Anta, Hector; Wang, Nan; Marti-Sanchez, Laura; Belloc, Eulalia; Garcia-Esparcia, Paula; Garrido, Juan J.; Ferrer, Isidro; Macias-Garcia, Daniel; Mir, Pablo; Artuch, Rafael; Perez, Belen; Hernandez, Felix; Navarro, Pilar; Luis Lopez-Sendon, Jose; Iglesias, Teresa; Yang, X. William; Mendez, Raul; Lucas, Jose J. 分享 收藏
HUNTINGTIN-MEDIATED AXONAL TRANSPORT REQUIRES ARGININE METHYLATION BY PRMT6 Migazzi, Alice; Scaramuzzino, Chiara; Anderson, Eric; Tripathy, Debasmita; Hernandez, Ivo H.; Grant, Rogan; Roccuzzo, Michela; Tosatto, Laura; Virlogeux, Amandine; Zuccato, Chiara; Caricasole, Andrea; Ratovitski, Tamara; Ross, Christopher A.; Pandey, Udai; Lucas, Jose J.; Saudou, Frederic; Pennuto, Maria; Basso, Manuela 分享 收藏
CPEB ALTERATION AND ABERRANT TRANSCRIPTOME-POLYADENYLATION UNVEIL A TREATABLE VITAMIN B1 DEFICIENCY IN HUNTINGTON'S DISEASE Pico, Sara; Parras, Alberto; Santos-Galindo, Maria; Pose-Utrilla, Julia; Castro, Margarita; Fraga, Enrique; Hernandez, Ivo H.; Elorza, Ainara; Anta, Hector; Wang, Nan; Marti-Sanchez, Laura; Belloc, Eulalia; Garcia-Esparcia, Paula; Garrido, Juan J.; Ferrer, Isidro; Macias-Garcia, Daniel; Mir, Pablo; Artuch, Rafael; Perez, Belen; Hernandez, Felix; Navarro, Pilar; Lopez-Sendon, Jose Luis; Iglesias, Teresa; Yang, X. William; Mendez, Raul; Lucas, Jose J. 分享 收藏
A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer's disease Garcia-Escudero, Vega; Ruiz-Gabarre, Daniel; Gargini, Ricardo; Perez, Mar; Garcia, Esther; Cuadros, Raquel; Hernandez, Ivo H.; Cabrera, Jorge R.; Garcia-Escudero, Ramon; Lucas, Jose J.; Hernandez, Felix; Avila, Jesus 分享 收藏
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6 Migazzi, Alice; Scaramuzzino, Chiara; Anderson, Eric N.; Tripathy, Debasmita; Hernandez, Ivo H.; Grant, Rogan A.; Roccuzzo, Michela; Tosatto, Laura; Virlogeux, Amandine; Zuccato, Chiara; Caricasole, Andrea; Ratovitski, Tamara; Ross, Christopher A.; Pandey, Udai B.; Lucas, Jose J.; Saudou, Frederic; Pennuto, Maria; Basso, Manuela 分享 收藏
Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors 亨廷顿病特异性错误剪接揭示了关键效应基因和剪接因子的改变 Elorza, Ainara; Marquez, Yamile; Cabrera, Jorge R.; Luis Sanchez-Trincado, Jose; Santos-Galindo, Maria; Hernandez, Ivo H.; Pico, Sara; Diaz-Hernandez, Juan, I; Garcia-Escudero, Ramon; Irimia, Manuel; Lucas, Jose J. 分享 收藏
High concordance between hippocampal transcriptome of the mouse intra-amygdala kainic acid model and human temporal lobe epilepsy Conte, Giorgia; Parras, Alberto; Alves, Mariana; Olla, Ivana; De Diego-Garcia, Laura; Beamer, Edward; Alalqam, Razi; Ocampo, Alejandro; Mendez, Raul; Henshall, David C.; Lucas, Jose J.; Engel, Tobias 分享 收藏
Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy Parras, Alberto; De Diego-Garcia, Laura; Alves, Mariana; Beamer, Edward; Conte, Giorgia; Jimenez-Mateos, Eva M.; Morgan, James; Olla, Ivana; Hernandez-Santana, Yasmina; Delanty, Norman; Farrell, Michael A.; O'Brien, Donncha F.; Ocampo, Alejandro; Henshall, David C.; Mendez, Raul; Lucas, Jose J.; Engel, Tobias 分享 收藏
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