未登录 Graft-derived VWF drives platelet activation and thrombocytopenia during porcine liver xenotransplantation to brain-dead human recipients 移植来源的VWF在猪肝异种移植至脑死亡人类受者期间驱动血小板激活和血栓性血小板减少症 Zhao, Liang; Apostolidis, Sokratis A.; Suzuki, Aae; Sarkar, Amrita; Guo, Qian; Li, Felix; Sagar, Alex; Fallon, John; Elzawahry, Mohamed A.; Abbas, Syed Hussain; Lanieri, Leanne; Getchell, Kristen; Low, Susan C.; Olthoff, Kim M.; Furth, Emma E.; Keating, Brendan J.; Friend, Peter; Poncz, Mortimer; Shaked, Abraham; Abrams, Charles S. 分享 收藏
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Transcription factor RUNX1 regulates coagulation factor XIII-A (F13A1): decreased platelet-megakaryocyte F13A1 expression and clot contraction in RUNX1 haplodeficiency 转录因子RUNX1调节凝血因子xiii-a (F13A1): RUNX1单倍缺乏症中血小板-巨核细胞F13A1表达减少和血块收缩 Del Carpio-Cano, Fabiola; Songdej, Natthapol; Guan, Liying; Mao, Guangfen; Goldfinger, Lawrence E.; Wurtzel, Jeremy G. T.; Lee, Kiwon; Lambert, Michele P.; Poncz, Mortimer; Rao, A. Koneti 分享 收藏
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The PF4-Centric Immunothrombotic Disorders, HIT, Vitt and APS, Lead to Complement Activation Responsive to Complement-Blocking Therapeutics 以PF4为中心的免疫血栓性疾病，HIT、VITT和APS，可引发对补体阻断疗法的补体激活响应。 Sarkar, Amrita; Field, Conroy O.; Mccrae, Keith R.; Ortel, Thomas L.; Arepally, Gow; Cofiell, Roxanne; Kim, Sung-Kwon; Rauova, Lubica; Poncz, Mortimer 分享 收藏
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Anti-Phospholipid Syndrome (APS) Antibody (Ab)-Induced Thrombosis Can be Blocked By Platelet Factor 4 (PF4)-Directed Abs: A Novel Therapeutic Approach for APS? 抗磷脂综合征（APS）抗体（Ab）诱导的血栓可通过血小板因子4（PF4）定向抗体（Abs）阻断：这是APS的一种新型治疗策略？ Sarkar, Amrita; Yadav, Santosh K.; Field, Conroy O.; Gollomp, Kandace; Mccrae, Keith R.; Ortel, Thomas L.; Gruel, Yves; Rollin, Jerome; Arepally, Gowthami M.; Rauova, Lubica; Cines, Douglas B.; Poncz, Mortimer 分享 收藏
PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertension PAI-1缺乏导致肺血管平滑肌重塑和肺动脉高压 Kudryashova, Tatiana V.; Zaitsev, Sergei V.; Jiang, Lifeng; Buckley, Benjamin J.; Mcguckin, Joshua P.; Goncharov, Dmitry; Zhyvylo, Iryna; Lin, Derek; Newcomb, Geoffrey; Piper, Bryce; Bogamuwa, Srimathi; Saiyed, Aisha; Teos, Leyla; Pena, Andressa; Ranson, Marie; Greenland, John R.; Wolters, Paul J.; Kelso, Michael J.; Poncz, Mortimer; Delisser, Horace M.; Cines, Douglas B.; Goncharova, Elena A.; Farkas, Laszlo; Stepanova, Victoria 分享 收藏
Marginated Neutrophils in the Lungs Effectively Compete for Nanoparticles Targeted to the Endothelium, Serving as a Part of the Reticuloendothelial System Zamora, Marco E.; Essien, Eno-Obong; Bhamidipati, Kartik; Murthy, Aditi; Liu, Jing; Kim, Hyunjun; Patel, Manthan N.; Nong, Jia; Wang, Zhicheng; Espy, Carolann; Chaudhry, Fatima N.; Ferguson, Laura T.; Tiwari, Sachchidanand; Hood, Elizabeth D.; Marcos-Contreras, Oscar A.; Omo-Lamai, Serena; Shuvaeva, Tea; Arguiri, Evguenia; Wu, Jichuan; Rauova, Lubica; Poncz, Mortimer; Basil, Maria C.; Cantu, Edward; Planer, Joseph D.; Spiller, Kara; Zepp, Jarod; Muzykantov, Vladimir R.; Myerson, Jacob W.; Brenner, Jacob S. 分享 收藏
Packaging of supplemented urokinase into alpha granules of in vitro-grown megakaryocytes for targeted nascent clot lysis Poncz, Mortimer; Zaitsev, Sergei, V; Ahn, Hyunsook; Kowalska, M. Anna; Bdeir, Khalil; Dergilev, Konstantin, V; Ivanciu, Lacramioara; Camire, Rodney M.; Cines, Douglas B.; Stepanova, Victoria 分享 收藏
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Inhibition of cellular activation induced by platelet factor 4 via the CXCR3 pathway ameliorates Japanese encephalitis and dengue viral infections Singh, Anamika; Ghosh, Riya; Asuru, Tejeswara Rao; Prajapat, Surendra K.; Joshi, Garima; Gaur, Kishan K.; Shrimali, Nishith M.; Ojha, Amrita; Vikram, Naval K.; Poncz, Mortimer; Kalia, Manjula; Guchhait, Prasenjit 分享 收藏
Platelet factor 4 limits neutrophil extracellular trap- and cell-free DNA-induced thrombogenicity and endothelial injury 血小板因子4限制中性粒细胞胞外陷阱和无细胞DNA诱导的血栓形成性和内皮损伤 Ngo, Anh T. P.; Skidmore, Abigail; Oberg, Jenna; Yarovoi, Irene; Sarkar, Amrita; Levine, Nate; Bochenek, Veronica; Zhao, Guohua; Rauova, Lubica; Kowalska, M. Anna; Eckart, Kaitlyn; Mangalmurti, Nilam S.; Rux, Ann; Cines, Douglas B.; Poncz, Mortimer; Gollomp, Kandace 分享 收藏
Treatment of thrombocytopenia and thrombosis in HIT in mice using deglycosylated KKO: a novel therapeutic? Sarkar, Amrita; Khandelwal, Sanjay; Koma, Gavin T.; Kim, Hyunjun; Gruel, Yves; Rollin, Jerome; Passam, Freda; Wool, Geoffrey D.; Arepally, Gowthami M.; Cines, Douglas B.; Rauova, Lubica; Poncz, Mortimer 分享 收藏
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Modulation of ultralarge immune complexes in heparin- induced thrombocytopenia Cai, Zheng; Bdeir, Khalil; Yarovoi, Serge, V; Rauova, Lubica; Arepally, Gowthami M.; Khandelwal, Sanjay; Rollin, Jerome; Gruel, Yves; Zaitsev, Sergei; Poncz, Mortimer; Greene, Mark I.; Cines, Douglas B. 分享 收藏
Platelet factor 4 (CXCL4/PF4) upregulates matrix metalloproteinase-2 (MMP-2) in gingival fibroblasts Le, Hoa T.; Golla, Kalyan; Karimi, Ryan; Hughes, Michael R.; Lakschevitz, Flavia; Cines, Douglas B.; Kowalska, M. Anna; Poncz, Mortimer; McNagny, Kelly M.; Hakkinen, Lari; Kim, Hugh 分享 收藏
Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model Borst, Sara; Nations, Catriana C.; Klein, Joshua G.; Pavani, Giulia; Maguire, Jean Ann; Camire, Rodney M.; Drazer, Michael W.; Godley, Lucy A.; French, Deborah L.; Poncz, Mortimer; Gadue, Paul 分享 收藏
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