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Paul K. Brindle

University of Pennsylvania

H指数:41

被引数:1.2万

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A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27201

OAAI

Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27207

OAAI

Histone Acetyltransferase CBP Is Vital To Demarcate Conventional and Innate CD8+ T-Cell Development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2157

OAAI

Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-Regulatory Cell Development and Function

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2075

OAAI

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation

IF7.5

2017-12-0727

OAAI

Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal

HUMAN MOLECULAR GENETICS

IF3.2

2017-11-1441

OAAI

The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma

CANCER DISCOVERY

IF33.3

2017-03-05178

OAAI

Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation

通过磷酸化和乙酰化对信号依赖性激活剂的组合调节

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-11-1726

OAAI

Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways

IF3.4

2014-10-2734

OAAI

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression

NUCLEIC ACIDS RESEARCH

IF13.1

2014-09-2331

OAAI

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis

IF3.4

2014-02-1330

PREAI

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment

IF3.6

2014-02-0152

OA

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300

NUCLEIC ACIDS RESEARCH

IF13.1

2013-09-1261

OAAI

Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity

NATURE MEDICINE

IF50

2013-08-18189

OAAI

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

整合基因组分析确定小细胞肺癌的关键体细胞驱动突变

NATURE GENETICS

IF31.8

2012-09-021.2K

OA

Peifer, Martin; Fernandez-Cuesta, Lynnette; Sos, Martin L.; George, Julie; Seidel, Danila; Kasper, Lawryn H.; Plenker, Dennis; Leenders, Frauke; Sun, Ruping; Zander, Thomas; Menon, Roopika; Koker, Mirjam; Dahmen, Ilona; Mueller, Christian; Di Cerbo, Vincenzo; Schildhaus, Hans-Ulrich; Altmueller, Janine; Baessmann, Ingelore; Becker, Christian; de Wilde, Bram; Vandesompele, Jo; Boehm, Diana; Ansen, Sascha; Gabler, Franziska; Wilkening, Ines; Heynck, Stefanie; Heuckmann, Johannes M.; Lu, Xin; Carter, Scott L.; Cibulskis, Kristian; Banerji, Shantanu; Getz, Gad; Park, Kwon-Sik; Rauh, Daniel; Gruetter, Christian; Fischer, Matthias; Pasqualucci, Laura; Wright, Gavin; Wainer, Zoe; Russell, Prudence; Petersen, Iver; Chen, Yuan; Stoelben, Erich; Ludwig, Corinna; Schnabel, Philipp; Hoffmann, Hans; Muley, Thomas; Brockmann, Michael; Engel-Riedel, Walburga; Muscarella, Lucia A.; Fazio, Vito M.; Groen, Harry; Timens, Wim; Sietsma, Hannie; Thunnissen, Erik; Smit, Egbert; Heideman, Danielle A. M.; Snijders, Peter J. F.; Cappuzzo, Federico; Ligorio, Claudia; Damiani, Stefania; Field, John; Solberg, Steinar; Brustugun, Odd Terje; Lund-Iversen, Marius; Saenger, Joerg; Clement, Joachim H.; Soltermann, Alex; Moch, Holger; Weder, Walter; Solomon, Benjamin; Soria, Jean-Charles; Validire, Pierre; Besse, Benjamin; Brambilla, Elisabeth; Brambilla, Christian; Lantuejoul, Sylvie; Lorimier, Philippe; Schneider, Peter M.; Hallek, Michael; Pao, William; Meyerson, Matthew; Sage, Julien; Shendure, Jay; Schneider, Robert; Buettner, Reinhard; Wolf, Juergen; Nuernberg, Peter; Perner, Sven; Heukamp, Lukas C.; Brindle, Paul K.; Haas, Stefan; Thomas, Roman K.

Is histone acetylation the most important physiological function for CBP and p300?

IF3.9

2012-04-16115

OAAI

Disrupting the CH1 Domain Structure in the Acetyltransferases CBP and p300 Results in Lean Mice with Increased Metabolic Control

CELL METABOLISM

IF30.9

2011-08-0137

OA

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

GCN5/PCAF介导的H3K9ac和CBP/p300-mediated H3K18/27ac在核受体反式激活中的不同作用

IF8.3

2010-12-03712

OAAI

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation

CBP/p300双空细胞揭示共激活因子水平和多样性对CREB反式激活的影响

IF8.3

2010-09-21106

OAAI

Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms

IF8.3

2007-05-24127

OAAI