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D

David J. DiLillo

University of Nebraska System
H指数:33
被引数:8,289

个人简介

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荣誉奖项

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CAR T cells based on fully human T cell receptor-mimetic antibodies exhibit potent antitumor activity in vivo

基于全人源T细胞受体模拟抗体的CAR T细胞在体内表现出强大的抗肿瘤活性。

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2025-03-260
PRE
Salzler, Robert; Dilillo, David J.; Saotome, Kei; Bray, Kevin; Mohrs, Katja; Hwang, Haun; Cygan, Kamil J.; Shah, Darshit; Rye-Weller, Anna; Kundu, Kunal; Badithe, Ashok; Zhang, Xiaoqin; Garnova, Elena; Torres, Marcela; Dhanik, Ankur; Babb, Robert; Delfino, Frank J.; Thwaites, Courtney; Dudgeon, Drew; Moore, Michael J.; Meagher, Thomas Craig; Decker, Corinne E.; Owczarek, Tomasz; Gleason, John A.; Yang, Xiaoran; Suh, David; Lee, Wen-Yi; Welsh, Richard; Macdonald, Douglas; Hansen, Johanna; Guo, Chunguang; Kirshner, Jessica R.; Thurston, Gavin; Huang, Tammy; Franklin, Matthew C.; Yancopoulos, George D.; Lin, John C.; Macdonald, Lynn E.; Murphy, Andrew J.; Chen, Gang; Olsen, Olav; Olson, William C.
A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Ra strengthens T cell-mediated anti-tumor therapies
CELL REPORTS MEDICINE
IF10.6
2024-10-010
OAAI
Wu, Jiaxi; Bloch, Nicolin; Chang, Aaron Y.; Bhavsar, Ramandeep; Wang, Qingqing; Crawford, Alison; DiLillo, David J.; Vazzana, Kristin; Mohrs, Katja; Dudgeon, Drew; Patel, Supriya; Ahmed, Hassan; Garg, Vidur; Amatulli, Michael; Antao, Olivia Q.; Yan, Yuetian; Wang, Shunhai; Ramos, Willy; Krueger, Pamela; Adler, Christina; Ni, Min; Wei, Yi; Guo, Chunguang; Macdonald, Lynn; Huang, Tammy; Ullman, Erica; Hermann, Aynur; Yancopoulos, George D.; Murphy, Andrew J.; Davis, Samuel; Olson, William C.; Lin, John C.; Smith, Eric; Zhang, Tong
REGN10597: A PD-1-targeted, receptor-masked wild type IL-2 with improved therapeutic window for cancer immunotherapy
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-12-010
PRE
Wu, Jiaxi; Bloch, Nicolin; Chang, Aaron; Bhaysar, Ramandeep; Wang, Qingqing; Patel, Supriya; Garg, Vidur; Shakil, Hassan; Amatulli, Michael; Dudgeon, Drew; Yan, Yuetian; Wang, Shunhai; Ramos, Willy; Krueger, Pamela; Vazzana, Kristin; Crawford, Alison; Idun, Jacqueline; Decker, Corinne; DiLillo, David; Chandwani, Samira; Huang, Tammy; Kirshner, Jessica; Guo, Chungguang; Macdonald, Lynn; Ullman, Erica; Hermann, Aynur; Olson, William; Davis, Samuel; Lin, John; Smith, Eric; Zhang, Tong
Humanization of T cell-mediated immunity in mice
SCIENCE IMMUNOLOGY
IF16.3
2021-12-2412
PRE
Moore, Michael J.; Zhong, Maggie; Hansen, Johanna; Gartner, Hans; Grant, Craig; Huang, Mei; Harris, Faith M.; Tu, Naxin; Bowerman, Natalie A.; Edelmann, Kurt H.; Barry, Thomas; Herbin, Olivier; Tay, Chin-Siean; DiLillo, David J.; Decker, Corinne E.; Levenkova, Natasha; Shevchuk, James; Dhanik, Ankur; Meagher, Karoline A.; Karr, Amanda; Roos, Jan; Lee, Wen-yi; Suh, David; Eckersdorff, Mark; Meagher, T. Craig; Koss, Matthew; Esau, Lakeisha; Sleeman, Matthew A.; Babb, Robert; Chen, Gang; Kyratsous, Christos A.; Poueymirou, William T.; McWhirter, John R.; Voronina, Vera A.; Guo, Chunguang; Gurer, Cagan; Yancopoulos, George D.; Murphy, Andrew J.; Macdonald, Lynn E.
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning

通过CD3亲和力调节产生具有细胞因子释放和生物分布的分化特征的T细胞重定向双特异性抗体

SCIENTIFIC REPORTS
IF3.9
2021-07-1364
OAAI
Haber, Lauric; Olson, Kara; Kelly, Marcus P.; Crawford, Alison; DiLillo, David J.; Tavare, Richard; Ullman, Erica; Mao, Shu; Canova, Lauren; Sineshchekova, Olga; Finney, Jennifer; Pawashe, Arpita; Patel, Supriya; McKay, Ryan; Rizvi, Sahar; Damko, Ermelinda; Chiu, Danica; Vazzana, Kristin; Ram, Priyanka; Mohrs, Katja; D'Orvilliers, Amanda; Xiao, Jenny; Makonnen, Sosina; Hickey, Carlos; Arnold, Cody; Giurleo, Jason; Chen, Ya Ping; Thwaites, Courtney; Dudgeon, Drew; Bray, Kevin; Rafique, Ashique; Huang, Tammy; Delfino, Frank; Hermann, Aynur; Kirshner, Jessica R.; Retter, Marc W.; Babb, Robert; MacDonald, Douglas; Chen, Gang; Olson, William C.; Thurston, Gavin; Davis, Samuel; Lin, John C.; Smith, Eric
Selection of CD3 affinity allows generation of T-cell redirecting bispecific antibodies with unique pharmacokinetic and biodistribution properties
CANCER RESEARCH
IF16.6
2020-08-151
PRE
Haber, Lauric; Olson, Kara; Babb, Robert; Kelly, Marcus; Crawford, Alison; Retter, Marc; DiLillo, David; Ullman, Erica; Finney, Jennifer; Canova, Lauren; Pawashe, Arpita; Chiu, Danica; Vazzana, Kristin; Ram, Priyanka; Mohrs, Katja; Dorvilliers, Amanda; Xiao, Jenny; Makonnen, Sosina; Hickey, Carlos; Arnold, Cody; Giurleo, Jason; Patel, Supriya; Tavare, Richard; Chen, Ya Ping; Chen, Gang; Olson, William; Thurston, Gavin; Lin, John Chia-Yang; Hermann, Aynur; Kirshner, Jessica; Smith, Eric J.

研究方向

暂未获取到该数据
J
Jeffrey V. Ravetch
H 指数:127论文数:391被引数:6.2万
T
Thomas F. Tedder
H 指数:123论文数:409被引数:5.1万
K
Katja Mohrs
H 指数:24论文数:68被引数:3,323
J
Jessica R. Kirshner
H 指数:22论文数:111被引数:3,541
J
John Lin
H 指数:33论文数:116被引数:4,082
G
Gavin Thurston
H 指数:79论文数:489被引数:3.1万
S
Stylianos Bournazos
H 指数:37论文数:89被引数:7,855
W
William C. Olson
H 指数:58论文数:379被引数:1.4万
C
Corinne E. Decker
H 指数:10论文数:39被引数:403
T
T. Craig Meagher
H 指数:7论文数:30被引数:328