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C

Charles H. Yoon

Brigham and Women's Hospital
H指数:31
被引数:1.4万

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Single-nucleus multimodal spatial transcriptomics reveals spatial colocalization of neoantigen-expressing tumor cells and cognate T cells

单核多模态空间转录组学揭示表达新抗原的肿瘤细胞与其配体T细胞的共定位

Nature Biotechnology
IF41.7
2026-07-220
PRE
Adi Nagler; Amit Sud; Jack Y. Ghannam; Lucas Pomerance; Camila Robles-Oteiza; Alexander B. Afeyan; Jackson A. Weir; Andrew J. C. Russell; Wesley S. Lu; McKayla Van Orden; Andrea Sonnenholzner; Giovanni J. Marrero; Qiyu Gong; Vipin Kumar; Kun Huang; Chloe Tu; Emma Lin; Bohoon Shim; Gabriel R. De Oliveira; MacLean C. Sellars; Charles H. Yoon; David A. Reardon; Toni K. Choueiri; Lars R. Olsen; Sabina Signoretti; Patrick A. Ott; David A. Braun; Giacomo Oliveira; Shuqiang Li; Kenneth J. Livak; Nir Hacohen; Fei Chen; Catherine J. Wu
Neoadjuvant intent anti-programmed death-1 immunotherapy for cutaneous squamous cell carcinoma in patients with hematologic malignancy

新辅助意向性抗程序性死亡-1免疫疗法治疗血液恶性肿瘤患者的皮肤鳞状细胞癌

Oncologist
IF4.2
2026-07-140
OAAI
Kyle Murchison, BS; Karam Khaddour, MD, MS; Anthony Camargo, BA; Emily Ruiz, MD, MPH; Rosh Sethi, MD, MPH; Eleni Rettig, MD; Charles Yoon, MD, PhD; Emily Y Kim, MD; Mia DeSimone, MD, MPH; Justine Cohen, DO; Nicole R LeBoeuf, MD, MPH; Nina Ran, MD, MS; Manisha Thakuria, MD; Ann W Silk, MD, MS; null
Tumor reactivity assessment using clonal expression reveals tumor reactive CD8+ T cell heterogeneity across solid tumors

使用克隆表达的肿瘤反应性评估揭示了实体瘤中肿瘤反应性CD8 T细胞的异质性

Frontiers in Immunology
IF5.9
2026-04-160
OAAI
DM David Monteiro; JD Jack Denebeim; AE Anne E. Dodson; AY Ashish Yeri; MG Mitali Ghose; MT Meghan Travers; SC Sophie Capobianco; CC Conor Calnan; GJ Gustavo J. Martinez; CH Charles H. Yoon; KW Karrie Wong; MJ Micah J. Benson; DS Dipen Sangurdekar
Progression patterns and clinical outcomes in patients with cutaneous squamous-cell carcinoma following anti-PD-1 therapy failure

进展模式和临床结局：抗PD-1治疗失败后皮肤鳞状细胞癌患者的观察

ESMO Open
IF8.3
2026-03-110
OAAI
K. Khaddour; P. Kote; M. Liu; A. Giobbie-Hurder; I. Dryg; A. Goyal; J.P. Guenette; J.D. Schoenfeld; D.N. Margalit; R.B. Tishler; E.M. Rettig; R.K.V. Sethi; D.J. Annino; L.A. Goguen; R. Uppaluri; C. Yoon; M. de Simone; N.A. Ran; J. Stevens; A.H. Waldman
A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma

多佐剂个性化新抗原疫苗在黑素瘤中产生强效免疫

Cell
IF42.5
2025-07-100
PRE
Eryn Blass; Derin B. Keskin; Chloe R. Tu; Cleo Forman; Allison Vanasse; Haley E. Sax; Bohoon Shim; Vipheaviny Chea; Nawoo Kim; Isabel Carulli; Jackson Southard; Haoxiang Lyu; Wesley Lu; Micah Rickles-Young; Alexander B. Afeyan; Oriol Olive; Ambica Mehndiratta; Haley Greenslade; Keerthi Shetty; Joanna Baginska; Ilana Gomez Diaz; Allison Nau; Kathleen L. Pfaff; Andrew Gans; Srinika Ranasinghe; Elizabeth I. Buchbinder; Tamara A. Sussman; Megan L. Insco; Charles H. Yoon; Scott J. Rodig; Sachet A. Shukla; Shuqiang Li; Jon C. Aster; David A. Braun; Carrie Cibulskis; Nir Hacohen; Donna S. Neuberg; Anita Giobbie-Hurder; Kenneth J. Livak; Edward F. Fritsch; Giacomo Oliveira; Jeremy M. Simon; Catherine J. Wu; Patrick A. Ott
Adjuvant Pembrolizumab in Stage II Melanoma: Outcomes by Primary Tumor Location in the Randomized, Double-Blind, Phase III KEYNOTE-716 Trial

Pembrolizumab在II期黑色素瘤中的辅助治疗: 随机，双盲，III期KEYNOTE-716试验中原发性肿瘤位置的结果

ANNALS OF SURGICAL ONCOLOGY
IF3.5
2025-02-010
PRE
Yoon, Charles H.; Ross, Merrick I.; Gastman, Brian R.; Luke, Jason J.; Ascierto, Paolo A.; Long, Georgina V.; Rutkowski, Piotr; Khattak, Muhammad; Del Vecchio, Michele; de la Cruz Merino, Luis; Mackiewicz, Jacek; Chiarion-Sileni, Vanna; Schadendorf, Dirk; Carlino, Matteo S.; Zhao, Yujie; Fukunaga-Kalabis, Mizuho; Krepler, Clemens; Eggermont, Alexander M. M.; Gershenwald, Jeffrey E.; Sondak, Vernon K.
Slide-tags enables single-nucleus barcoding for multimodal spatial genomics

Slide-tags实现了多模态空间基因组学的单核条形码

Nature
IF48.5
2023-12-130
OAAI
Andrew J. C. Russell; Jackson A. Weir; Naeem M. Nadaf; Matthew Shabet; Vipin Kumar; Sandeep Kambhampati; Ruth Raichur; Giovanni J. Marrero; Sophia Liu; Karol S. Balderrama; Charles R. Vanderburg; Vignesh Shanmugam; Luyi Tian; J. Bryan Iorgulescu; Charles H. Yoon; Catherine J. Wu; Evan Z. Macosko; Fei Chen
Cancer sensitivity to therapy is constrained by apoptosis regulation in cells of origin
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Fraser, Cameron; Qin, Xingping; Shimada, Kenichi; Spetz, Johan; Florido, Mary Heather; Singh, Rumani; Yu, Stacey; Presser, Adam; Inde, Zintis; Joshi, Gaurav; Guerriero, Jennifer; Sanchez-Rivera, Francisco; Karst, Alison; Lopez, Omar; Li, Chendi; Winter, Peter; Yue, Ying; Sorger, Peter; Cheng, Jingwei; Lossos, Izidore; Hata, Aaron; Drapkin, Ronny; Palmer, Adam; Decaprio, James; Thakuria, Manisha; Yoon, Charles; Matulonis, Ursula; Meyerson, Matthew; Stover, Elizabeth; Cardona, Diana; Wood, Kris; Sarosiek, Shayna; Kirsch, David; Mancias, Joseph; Cherniack, Andrew; Letai, Anthony; Sarosiek, Kristopher
A non-canonical MiT/TFE-dependent NRF2 program is a druggable vulnerability in multiple cancer types
CANCER RESEARCH
IF16.6
2023-04-041
PRE
Luo, Xinbo; Lutterbach, Bart; Pancholi, Priya; Choi, Yeon Sook; Liu, Xiao; Munson, Phillip; Faisal, Saqib; Whipple, David A.; Smith, Robert A.; Weiner, Warren S.; Johnson, David K.; Boukhali, Myriam; Persky, Nicole S.; Rees, Matthew G.; Kitajima, Shunsuke; Barbie, David; Roy, Anuradha; Baltezor, Michael; Rajewski, Lian; McGuinness, William; Haslam, John; Sadagopan, Ananthan; Yoon, Charles H.; Johannessen, Cory M.; Lian, Christine G.; Hornick, Jason L.; Viswanathan, Srinivas R.; Liu, David; Nienaber, Vicki; Haas, Wilhelm; Schoenen, Frank J.; Fisher, David E.; Haq, Rizwan
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

个人新抗原疫苗在黑色素瘤患者中诱导持续记忆T细胞反应和表位扩散

NATURE MEDICINE
IF50
2021-01-21321
OAAI
Hu, Zhuting; Leet, Donna E.; Allesoe, Rosa L.; Oliveira, Giacomo; Li, Shuqiang; Luoma, Adrienne M.; Liu, Jinyan; Forman, Juliet; Huang, Teddy; Iorgulescu, J. Bryan; Holden, Rebecca; Sarkizova, Siranush; Gohil, Satyen H.; Redd, Robert A.; Sun, Jing; Elagina, Liudmila; Giobbie-Hurder, Anita; Zhang, Wandi; Peter, Lauren; Ciantra, Zoe; Rodig, Scott; Olive, Oriol; Shetty, Keerthi; Pyrdol, Jason; Uduman, Mohamed; Lee, Patrick C.; Bachireddy, Pavan; Buchbinder, Elizabeth I.; Yoon, Charles H.; Neuberg, Donna; Pentelute, Bradley L.; Hacohen, Nir; Livak, Kenneth J.; Shukla, Sachet A.; Olsen, Lars Ronn; Barouch, Dan H.; Wucherpfennig, Kai W.; Fritsch, Edward F.; Keskin, Derin B.; Wu, Catherine J.; Ott, Patrick A.
Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade
CANCER DISCOVERY
IF33.3
2020-09-0156
OAAI
Gstalder, Cecile; Liu, David; Miao, Diana; Lutterbach, Bart; DeVine, Alexander L.; Lin, Chenyu; Shettigar, Megha; Pancholi, Priya; Buchbinder, Elizabeth, I; Carter, Scott L.; Manos, Michael P.; Rojas-Rudilla, Vanesa; Brennick, Ryan; Gjini, Evisa; Chen, Pei-Hsuan; Lako, Ana; Rodig, Scott; Yoon, Charles H.; Freeman, Gordon J.; Barbie, David A.; Hodi, F. Stephen; Miles, Wayne; Van Allen, Eliezer M.; Haq, Rizwan

研究方向

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