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J

Joshua T. Schiffer

fred hutchison cancer center

44H指数
289论文数
7.4K被引数
收录论文 110
发表时间
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Efficacy and Safety of Pritelivir Versus Foscarnet for the Treatment of Acyclovir-Refractory Herpes Simplex Virus Infection in Immunocompromised Adults: A Randomized, Open-Label Phase 2 Trial普拉提利韦与福司卡奈特治疗阿昔洛韦耐药单纯疱疹病毒感染在免疫抑制成人中的疗效与安全性：一项随机、开放标签二期试验
errOpen Forum Infectious Diseases
IF3.8
err2026-08-31
err0
errOAAI
errCamille N Kotton; Kimberly A Workowski; Princy N Kumar; Robin K Avery; Roy F Chemaly; Nicolas C Issa; Moti Ramgopal; Joshua T Schiffer; Joerg Albrecht; Hollis R O’Neal Jr; Pranatharthi Chandrasekar; Tanya S Schreibman; Mayur Ramesh; Michael G Ison; Melanie E Sumner; Aaron Dane; Bernadette Surujbally; Burkhard Timmler; Manickam Rangaraju; Genofeva A Papanicolaou; Alexander Birkmann; Anna Wald; null
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Clinical trial simulation of antiviral drugs抗病毒药物的临床试验模拟
errJournal of Virology
IF3.8
err2026-05-19
err1
PREAI
errSchiffer, Joshua T.; Reeves, Daniel B.; Mayer, Bryan; Rodriguez, Lucero Rodriguez; Duke, Elizabeth R.; Haddock, Beatrix; Avila-Ponce de Leon, Ugo; Iwami, Shingo; Owens, Katherine; Esmaeili-Wellman, Shadi
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Genital herpes shedding episodes associate with altered spatial organization and activation of mucosal immune cells生殖器疱疹病毒脱落发作与黏膜免疫细胞的空间组织改变和激活相关联。
errJCI Insight
IF6.1
err2026-01-09
err1
PREAI
errMaclean, Finn; Zemek, Rachael M.; Tsegaye, Adino Tesfahun; Graham, Jessica B.; Swarts, Jessica L.; Vick, Sarah C.; Potchen, Nicole B.; Talavera, Irene Cruz; Warrier, Lakshmi; Dubrulle, Julien; Schroeder, Lena K.; Elz, Anna; Sowerby, David; Saito, Ayumi; Thomas, Katherine K.; Mack, Matthias; Schiffer, Joshua T.; McClelland, R. Scott; Jerome, Keith R.; Chohan, Bhavna H.; Ngure, Kenneth; Mugo, Nelly Rwamba; Newell, Evan W.; Lingappa, Jairam R.; Lund, Jennifer M.
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Orolabial and Genital Herpes Clinical Trials: A Meta-analysis of Endpoints口唇和生殖器疱疹临床试验: 终点的荟萃分析
errOPEN FORUM INFECTIOUS DISEASES
IF3.8
err2026-01-01
err0
errOAAI
errSloan, Abigail; Mortezavi, Mahta; Gerhart, Jacqueline; Banerjee, Anindita; Alami, Negar Niki; Najera, Isabel; Ahadieh, Sima; Dalam, Alexis Bernard; Schiffer, Joshua T.; Patel, Rajul; Johnston, Christine
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Human Herpes Virus-8 Oral Shedding Heterogeneity Is Due to Varying Rates of Reactivation from Latency and Immune Containment人类疱疹病毒-8口腔排毒异质性是由于潜伏期再激活率和免疫控制率的差异所致。
errViruses 2025, Vol. 17, Page 1500
IF3.5
err2025-11-18
err0
errOAAI
errDavid A. Swan; Elizabeth M. Krantz; Catherine M. Byrne; Fred Okuku; Janet Nankoma; Innocent Mutyaba; Warren Phipps; Joshua T. Schiffer
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Molnupiravir clinical trial simulation suggests that polymerase chain reaction underestimates antiviral potency against SARS-CoV-2
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-11-03
err0
errOAAI
errEsmaeili, Shadisadat; Owens, Katherine; Leon, Ugo Avila-Ponce De; Standing, Joseph F.; Lowe, David M.; Zhang, Shengyuan; Watson, James A.; Schilling, William H. K.; Wagoner, Jessica; Polyak, Stephen J.; Schiffer, Joshua T.
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Mild HIV-specific selective forces overlaying natural CD4+ T cell dynamics explain the clonality and decay dynamics of HIV reservoir cells轻度HIV特异性选择压力叠加于自然CD4+ T细胞动力学，解释了HIV储库细胞的克隆性和衰减动力学。
errCell Systems
IF7.7
err2025-09-22
err0
PREAI
errDaniel B. Reeves; Danielle N. Rigau; Arianna Romero; Hao Zhang; Francesco R. Simonetti; Joseph Varriale; Rebecca Hoh; Li Zhang; Kellie N. Smith; Luis J. Montaner; Leah H. Rubin; Stephen J. Gange; Nadia R. Roan; Phyllis C. Tien; Joseph B. Margolick; Michael J. Peluso; Steven G. Deeks; Joshua T. Schiffer; Janet D. Siliciano; Robert F. Siliciano; Annukka A.R. Antar
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Estimating Population Immunity and Impact of COVID-19 Vaccination in Washington State and Oregon估计华盛顿州和俄勒冈州的人口免疫和COVID-19疫苗接种影响
errOPEN FORUM INFECTIOUS DISEASES
IF3.8
err2025-09-01
err0
errOAAI
errMoore, Mia; Anderson, Larissa; Bracis, Chloe; Swan, David A.; Painter, Ian; Everson, Erik; Janes, Holly; Schiffer, Joshua T.; Matrajt, Laura; Dimitrov, Dobromir
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Quantitative viral dynamics: Methods for parameter estimation定量病毒动力学：参数估计方法
errVirology
IF2.4
err2025-07-24
err0
errOAAI
errAngela Tower; Katherine Owens; Shadisadat Esmaeili; Joshua T. Schiffer; Daniel B. Reeves; Elissa J. Schwartz
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Viral Dynamic Models During COVID-19: Are We Ready for the Next Pandemic?COVID-19期间的病毒动力学模型：我们为下一次大流行做好准备了吗？
errcpt pharmacometrics systems pharmacology
IF0
err2025-06-02
err0
errOAAI
errAurelien Marc; Joshua T. Schiffer; France Mentré; Alan S. Perelson; Jérémie Guedj
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Intact HIV DNA decays in children with and without complete viral load suppression完整HIV DNA在有无完全病毒载量抑制的儿童中发生衰减
errPLOS PATHOGENS
IF4.9
err2025-04-04
err0
errOAAI
errReeves, Daniel B.; Litchford, Morgan; Fish, Carolyn S.; Farrell-Sherman, Anna; Poindexter, Makayla; Ahmed, Nashwa; Cassidy, Noah A. J.; Neary, Jillian; Wamalwa, Dalton; Langat, Agnes; Chebet, Daisy; Moraa, Hellen; Antar, Annukka A. R.; Slyker, Jennifer; Benki-Nugent, Sarah; Cohn, Lillian B.; Schiffer, Joshua T.; Overbaugh, Julie; Lehman, Dara A.
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homeRNA self-blood collection enables high-frequency temporal profiling of presymptomatic host immune kinetics to respiratory viral infection: a prospective cohort studyhomeRNA自我采血技术可实现呼吸道病毒感染前驱症状期宿主免疫动力学的超高频率时间谱分析：一项前瞻性队列研究
errEBIOMEDICINE
IF10.8
err2025-02-01
err0
PREAI
errLim, Fang Yun; Lea, Hannah G.; Dostie, Ashley M.; Kim, Soo-Young; van Neel, Tammi L.; Hassan, Grant W.; Takezawa, Meg G.; Starita, Lea M.; Adams, Karen N.; Boeckh, Michael; Schiffer, Joshua T.; Hyrien, Ollivier; Waghmare, Alpana; Berthier, Erwin; Theberge, Ashleigh B.
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Ensemble modeling of SARS-CoV-2 immune dynamics in immunologically naive rhesus macaques predicts that potent, early innate immune responses drive viral elimination
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-11-07
err0
errOAAI
errByrne, Catherine; Schiffer, Joshua T.
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Highly Heterogeneous Kaposi Sarcoma-Associated Herpesvirus Oral Shedding Kinetics Among People With and Without Kaposi Sarcoma and Human Immunodeficiency Virus Coinfection
errOPEN FORUM INFECTIOUS DISEASES
IF3.8
err2024-09-23
err0
errOAAI
errKrantz, Elizabeth M.; Mutyaba, Innocent; Nankoma, Janet; Okuku, Fred; Casper, Corey; Orem, Jackson; Swan, David A.; Phipps, Warren; Schiffer, Joshua T.
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A unifying model to explain frequent SARS-CoV-2 rebound after nirmatrelvir treatment and limited prophylactic efficacy
errNATURE COMMUNICATIONS
IF15.7
err2024-06-28
err2
errOAAI
errEsmaeili, Shadisadat; Owens, Katherine; Wagoner, Jessica; Polyak, Stephen J.; White, Judith M.; Schiffer, Joshua T.
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Heterogeneous SARS-CoV-2 kinetics due to variable timing and intensity of immune responses
errJCI INSIGHT
IF6.1
err2024-04-04
err7
errOAAI
errOwens, Katherine; Esmaeili, Shadisadat; Schiffer, Joshua T.
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Two-way pharmacodynamic modeling of drug combinations and its application to pairs of repurposed Ebola and SARS-CoV-2 agents药物组合的双向药效学模型及其在重新使用的埃博拉和SARS-CoV-2药物对中的应用
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-04-03
err2
errOAAI
errXu, Shuang; Esmaeili, Shadisadat; Cardozo-Ojeda, E. Fabian; Goyal, Ashish; White, Judith M.; Polyak, Stephen J.; Schiffer, Joshua T.
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High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials ( vol 14 , 8299 , 2023)
errNATURE COMMUNICATIONS
IF15.7
err2024-03-22
err0
errOAAI
errReeves, Daniel B.; Mayer, Bryan T.; DeCamp, Allan C.; Huang, Yunda; Zhang, Bo; Carpp, Lindsay N.; Magaret, Craig A.; Juraska, Michal; Gilbert, Peter B.; Montefiori, David C.; Bar, Katharine J.; Cardozo-Ojeda, E. Fabian; Schiffer, Joshua T.; Rossenkhan, Raabya; Edlefsen, Paul; Morris, Lynn; Mkhize, Nonhlanhla N.; Williamson, Carolyn; Mullins, James I.; Seaton, Kelly E.; Tomaras, Georgia D.; Andrew, Philip; Mgodi, Nyaradzo; Ledgerwood, Julie E.; Cohen, Myron S.; Corey, Lawrence; Naidoo, Logashvari; Orrell, Catherine; Goepfert, Paul A.; Casapia, Martin; Sobieszczyk, Magdalena E.; Karuna, Shelly T.; Edupuganti, Srilatha
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High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials
errNATURE COMMUNICATIONS
IF15.7
err2023-12-14
err4
errOAAI
errReeves, Daniel B.; Mayer, Bryan T.; Decamp, Allan C.; Huang, Yunda; Zhang, Bo; Carpp, Lindsay N.; Magaret, Craig A.; Juraska, Michal; Gilbert, Peter B.; Montefiori, David C.; Bar, Katharine J.; Cardozo-Ojeda, E. Fabian; Schiffer, Joshua T.; Rossenkhan, Raabya; Edlefsen, Paul; Morris, Lynn; Mkhize, Nonhlanhla N.; Williamson, Carolyn; Mullins, James I.; Seaton, Kelly E.; Tomaras, Georgia D.; Andrew, Philip; Mgodi, Nyaradzo; Ledgerwood, Julie E.; Cohen, Myron S.; Corey, Lawrence; Naidoo, Logashvari; Orrell, Catherine; Goepfert, Paul A.; Casapia, Martin; Sobieszczyk, Magdalena E.; Karuna, Shelly T.; Edupuganti, Srilatha
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High-frequency home self-collection of capillary blood correlates IFI27 expression kinetics with SARS-CoV-2 viral clearance
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-12-01
err1
errOAAI
errLim, Fang Yun; Kim, Soo-Young; Kulkarni, Karisma N.; Blazevic, Rachel L.; Kimball, Louise E.; Lea, Hannah G.; Haack, Amanda J.; Gower, Maia S.; Stevens-Ayers, Terry; Starita, Lea M.; Boeckh, Michael; Hyrien, Ollivier; Schiffer, Joshua T.; Theberge, Ashleigh B.; Waghmare, Alpana
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研究方向

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合作期刊
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Michel C. Nussenzweig
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John R. Mascola
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Steven G. Deeks
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