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J

Jérôme Eeckhoute

institut national de la santé et de la recherche médicale (inserm)
H指数:43
被引数:2.9万

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Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation

上皮转录因子GRHL2的去抑制促进了直接的肝细胞到胆管细胞的转分化

PLOS BIOLOGY
IF7.2
2025-12-120
PRE
Vasseur, Ludivine; Gheeraert, Celine; Dubois-Chevalier, Julie; Very, Ninon; Guille, Loic; Bou Saleh, Mohamed; Boulet, Clemence; Sobolewski, Cyril; Loyer, Pascal; Berthier, Alexandre; Legrand, Noemie; Corlu, Anne; Gnemmi, Viviane; Lasailly, Guillaume; Leteurtre, Emmanuelle; Galinousky, Dmitry; Bongiovanni, Antonino; Taront, Solenne; Toft, Nicolaj I.; Grontved, Lars; Tulasne, David; Furlan, Alessandro; Ntandja-Wandji, Line Carolle; Staels, Bart; Lefebvre, Philippe; Dubuquoy, Laurent; Eeckhoute, Jerome
Alcohol-related hepatitis induces a specific fibrosis profile through YAP activation in myofibroblasts

酒精性肝炎通过激活肌成纤维细胞中的YAP诱导特定的纤维化表型。

JHEP Reports
IF7.5
2025-08-290
OAAI
Line Carolle Ntandja Wandji; Mohamed Bousaleh; Cyril Sobolewski; Mehdi El Amrani; Fabrice Bray; Emmanuel Boleslawski; Jérôme Eeckhoute; Pierre-Jean Devaux; François Maggiotto; Solenne Taront; Christian Rolando; Viviane Gnemmi; Philippe Mathurin; Laurent Dubuquoy; Alexandre Louvet
O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts

O-glcnacylation控制肌成纤维细胞中的促纤维化转录调节信号传导

CELL DEATH & DISEASE
IF9.6
2024-06-033
OAAI
Very, Ninon; Boulet, Clemence; Gheeraert, Celine; Berthier, Alexandre; Johanns, Manuel; Bou Saleh, Mohamed; Guille, Loic; Bray, Fabrice; Strub, Jean-Marc; Bobowski-Gerard, Marie; Zummo, Francesco P.; Vallez, Emmanuelle; Molendi-Coste, Olivier; Woitrain, Eloise; Cianferani, Sarah; Montaigne, David; Ntandja-Wandji, Line Carolle; Dubuquoy, Laurent; Dubois-Chevalier, Julie; Staels, Bart; Lefebvre, Philippe; Eeckhoute, Jerome
The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα
METABOLISM-CLINICAL AND EXPERIMENTAL
IF11.9
2024-02-011
OA
Clavreul, Ludivine; Bernard, Lucie; Cotte, Alexia K.; Hennuyer, Nathalie; Bourouh, Cyril; Devos, Claire; Helleboid, Audrey; Haas, Joel T.; Verrijken, An; Gheeraert, Celine; Derudas, Bruno; Guille, Loic; Chevalier, Julie; Eeckhoute, Jerome; Vallez, Emmanuelle; Dorchies, Emilie; Van Gaal, Luc; Lassailly, Guillaume; Francque, Sven; Staels, Bart; Paumelle, Rejane
Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD
JHEP REPORTS
IF7.5
2024-01-012
OAAI
Johanns, Manuel; Haas, Joel T.; Raverdy, Violetta; Vandel, Jimmy; Chevalier-Dubois, Julie; Guille, Loic; Derudas, Bruno; Legendre, Benjamin; Caiazzo, Robert; Verkindt, Helene; Gnemmi, Viviane; Leteurtre, Emmanuelle; Derhourhi, Mehdi; Bonnefond, Amelie; Froguel, Philippe; Eeckhoute, Jerome; Lassailly, Guillaume; Mathurin, Philippe; Pattou, Francois; Staels, Bart; Lefebvre, Philippe
Roux-en-Y gastric bypass induces hepatic transcriptomic signatures and plasma metabolite changes indicative of improved cholesterol homeostasis
JOURNAL OF HEPATOLOGY
IF33
2023-10-017
PRE
Lalloyer, Fanny; Mogilenko, Denis A.; Verrijken, Ann; Haas, Joel T.; Lamaziere, Antonin; Kouach, Mostafa; Descat, Amandine; Caron, Sandrine; Vallez, Emmanuelle; Derudas, Bruno; Gheeraert, Celine; Bauge, Eric; Despres, Gaetan; Dirinck, Eveline; Tailleux, Anne; Dombrowicz, David; Van Gaal, Luc; Eeckhoute, Jerome; Lefebvre, Philippe; Goossens, Jean-Francois; Francque, Sven; Staels, Bart
Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis

功能基因组学揭示了纤维化中肌成纤维细胞激活所需的转录因子BNC2

NATURE COMMUNICATIONS
IF15.7
2022-09-1016
OAAI
Bobowski-Gerard, Marie; Boulet, Clemence; Zummo, Francesco P.; Dubois-Chevalier, Julie; Gheeraert, Celine; Saleh, Mohamed Bou; Strub, Jean-Marc; Farce, Amaury; Ploton, Maheul; Guille, Loic; Vandel, Jimmy; Bongiovanni, Antonino; Very, Ninon; Woitrain, Eloise; Deprince, Audrey; Lalloyer, Fanny; Bauge, Eric; Ferri, Lise; Ntandja-Wandji, Line-Carolle; Cotte, Alexia K.; Grangette, Corinne; Vallez, Emmanuelle; Cianferani, Sarah; Raverdy, Violeta; Caiazzo, Robert; Gnemmi, Viviane; Leteurtre, Emmanuelle; Pourcet, Benoit; Paumelle, Rejane; Ravnskjaer, Kim; Lassailly, Guillaume; Haas, Joel T.; Mathurin, Philippe; Pattou, Francois; Dubuquoy, Laurent; Staels, Bart; Lefebvre, Philippe; Eeckhoute, Jerome
Loss of hepatocyte identity following aberrant YAP activation: A key mechanism in alcoholic hepatitis
JOURNAL OF HEPATOLOGY
IF33
2021-10-0144
OAAI
Saleh, Mohamed Bou; Louvet, Alexandre; Ntandja-Wandji, Line Carolle; Boleslawski, Emmanuel; Gnemmi, Viviane; Lassailly, Guillaume; Truant, Stephanie; Maggiotto, Francois; Ningarhari, Massih; Artru, Florent; Anglo, Emilie; Sancho-Bru, Pau; Corlu, Anne; Argemi, Josepmaria; Dubois-Chevalier, Julie; Dharancy, Sebastien; Eeckhoute, Jerome; Bataller, Ramon; Mathurin, Philippe; Dubuquoy, Laurent
Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver
MOLECULAR SYSTEMS BIOLOGY
IF7.7
2020-05-1437
OAAI
Dubois, Vanessa; Gheeraert, Celine; Vankrunkelsven, Wouter; Dubois-Chevalier, Julie; Dehondt, Helene; Bobowski-Gerard, Marie; Vinod, Manjula; Zummo, Francesco Paolo; Guiza, Fabian; Ploton, Maheul; Dorchies, Emilie; Pineau, Laurent; Boulinguiez, Alexis; Vallez, Emmanuelle; Woitrain, Eloise; Bauge, Eric; Lalloyer, Fanny; Duhem, Christian; Rabhi, Nabil; van Kesteren, Ronald E.; Chiang, Cheng-Ming; Lancel, Steve; Duez, Helene; Annicotte, Jean-Sebastien; Paumelle, Rejane; Vanhorebeek, Ilse; Van den Berghe, Greet; Staels, Bart; Lefebvre, Philippe; Eeckhoute, Jerome

研究方向

暂未获取到该数据
B
Bart Staels
H 指数:167论文数:1,195被引数:11.0万
P
Philippe Lefèbvre
H 指数:56论文数:282被引数:1.6万
C
Céline Gheeraert
H 指数:24论文数:50被引数:2,045
J
Julie Dubois‐Chevalier
H 指数:15论文数:39被引数:796
B
Bruno Derudas
H 指数:25论文数:49被引数:4,381
A
Alexandre Berthier
H 指数:12论文数:39被引数:1,037
F
Frédérik Oger
H 指数:20论文数:49被引数:1,284
M
Myles Brown
H 指数:127论文数:913被引数:8.5万
H
Hélène Duez
H 指数:46论文数:109被引数:1.4万
L
Loïc Guille
H 指数:6论文数:12被引数:115