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S

Steven P. Balk

Harvard Medical School
H指数:91
被引数:3.0万

个人简介

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教育背景

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工作经历

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荣誉奖项

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RNAs anchoring replication complex control initiation and firing of DNA replication

RNA锚定复制复合物控制DNA复制的起始和引发

Nature Communications
IF15.7
2026-05-010
OA
Ummarino, Simone; Poluben, Larysa; Ebralidze, Alexander K.; Autiero, Ida; Rinaldi, Lucrezia; Paniza, Theodore; Deshpande, Madhura; Mandel, Nicholas H.; Lee, Jonathan D.; Zhang, Yanzhou; Bassal, Mahmoud A.; Budnik, Bogdan; Trinh, Bon Q.; Balk, Steven P.; Flaumenhaft, Robert; Gerhardt, Jeannine; Mirkin, Sergei M.; Tenen, Daniel G.; Di Ruscio, Annalisa
Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion

雄激素剥夺介导的AKT激活在TMPRSS2:ERG融合的前列腺癌中增强

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2025-12-010
OA
Ma, Fen; Chen, Sen; Cecchi, Luigi; Ersoy-Fazlioglu, Betul; Russo, Joshua W.; Arai, Seiji; Awad, Seifeldin; Calagua, Carla; Xie, Fang; Poluben, Larysa; Voznesensky, Olga; Ku, Anson T.; Karzai, Fatima; Cai, Changmeng; Einstein, David J.; Ye, Huihui; Yuan, Xin; Toker, Alex; Taplin, Mary-Ellen; Sowalsky, Adam G.; Balk, Steven P.
Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer

阐明靶向MCL1的分子分层单药及联合治疗策略，以治疗致命性前列腺癌

Nature Communications
IF15.7
2025-10-080
OAAI
Juan M. Jiménez-Vacas; Daniel Westaby; Ines Figueiredo; Alexis De Haven Brandon; Ana Padilha; Wei Yuan; George Seed; Denisa Bogdan; Bora Gurel; Claudia Bertan; Susana Miranda; Maryou Lambros; Antonio J. Montero-Hidalgo; Ilsa Coleman; Ivan Pak Lok Yu; Lorenzo Buroni; Wanting Zeng; Antje J. Neeb; Jon Welti; Jan Rekowski; Roberta Paravati; Florian Gabel; Nicole Pandell; Ana Ferreira; Mateus Crespo; Ruth Riisnaes; Souvik Das; Joe Taylor; Nick Waldron; Emily Hobern; Melanie Valenti; Jian Ning; Ilona Bernett; Kate Liodaki; Thomas Persse; Patricia Galipeau; Scott Wilkinson; Shana Y. Trostel; Fatima Karzai; Cindy H. Chau; Erica L. Beatson; Xiaohu Zhang; Carleen Klumpp-Thomas; Andreas Varkaris; Raul M. Luque; Amanda Swain; Florence Raynaud; Nathan A. Lack; Craig J. Thomas; Gavin Ha; William D. Figg; Marco Bezzi; Adam G. Sowalsky; Peter S. Nelson; Suzanne Carreira; Steven P. Balk; Johann S. de Bono; Adam Sharp
Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancer

个体内表观遗传异质性是晚期前列腺癌表型亚型的基础

Nature Communications
IF15.7
2025-07-010
OAAI
Kei Mizuno; Sheng-Yu Ku; Varadha Balaji Venkadakrishnan; Martin K. Bakht; Michael Sigouros; Joanna Chan; Anna Trigos; Jordan H. Driskill; Jyothi Manohar; Abigail King; Adam G. Presser; Min Jin Kim; Alok K. Tewari; Henry W. Long; David Quigley; Toni K. Choueiri; Steven Balk; Sarah Hill; Juan Miguel Mosquera; David Einstein; Shahneen Sandhu; Mary-Ellen Taplin; Himisha Beltran
Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer

核因子I介导的染色质可及性增加驱动前列腺癌向雄激素受体剪接变异体依赖性转变

CELL REPORTS
IF6.9
2025-01-011
OA
Poluben, Larysa; Nouri, Mannan; Liang, Jiaqian; Chen, Shaoyong; Varkaris, Andreas; Ersoy-Fazlioglu, Betul; Voznesensky, Olga; Lee, Irene I.; Qiu, Xintao; Cato, Laura; Seo, Ji-Heui; Freedman, Matthew L.; Sowalsky, Adam G.; Lack, Nathan A.; Corey, Eva; Nelson, Peter S.; Brown, Myles; Long, Henry W.; Russo, Joshua W.; Balk, Steven P.
CDK9 inhibition constrains multiple oncogenic transcriptional and epigenetic pathways in prostate cancer (vol 131, pg 1092, 2024)
BRITISH JOURNAL OF CANCER
IF6.8
2024-10-240
OA
Rahman, Razia; Rahaman, Muhammed H.; Hanson, Adrienne R.; Choo, Nicholas; Xie, Jianling; Townley, Scott L.; Shrestha, Raj; Hassankhani, Ramin; Islam, Saiful; Ramm, Susanne; Simpson, Kaylene J.; Risbridger, Gail P.; Best, Giles; Centenera, Margaret M.; Balk, Steven P.; Kichenadasse, Ganessan; Taylor, Renea A.; Butler, Lisa M.; Tilley, Wayne D.; Conn, Simon J.; Lawrence, Mitchell G.; Wang, Shudong; Selth, Luke A.
CDK9 inhibition inhibits multiple oncogenic transcriptional and epigenetic pathways in prostate cancer
BRITISH JOURNAL OF CANCER
IF6.8
2024-08-082
OA
Rahman, Razia; Rahaman, Muhammed H.; Hanson, Adrienne R.; Choo, Nicholas; Xie, Jianling; Townley, Scott L.; Shrestha, Raj; Hassankhani, Ramin; Islam, Saiful; Ramm, Susanne; Simpson, Kaylene J.; Risbridger, Gail P.; Best, Giles; Centenera, Margaret M.; Balk, Steven P.; Kichenadasse, Ganessan; Taylor, Renea A.; Butler, Lisa M.; Tilley, Wayne D.; Conn, Simon J.; Lawrence, Mitchell G.; Wang, Shudong; Selth, Luke A.
Androgen receptor splice variants drive castrationresistant prostate cancer metastasis by activating distinct transcriptional programs
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-04-303
OAAI
Han, Dong; Labaf, Maryam; Zhao, Yawei; Owiredu, Jude; Zhang, Songqi; Patel, Krishna; Venkataramani, Kavita; Steinfeld, Jocelyn S.; Han, Wanting; Li, Muqing; Liu, Mingyu; Wang, Zifeng; Besschetnova, Anna; Patalano, Susan; Mulhearn, Michaela J.; Macoska, Jill A.; Yuan, Xin; Balk, Steven P.; Nelson, Peter S.; Plymate, Stephen R.; Gao, Shuai; Siegfried, Kellee R.; Liu, Ruihua; Stangis, Mary M.; Foxa, Gabrielle; Czernik, Piotr J.; Williams, Bart O.; Zarringhalam, Kourosh; Li, Xiaohong; Cai, Changmeng
BCL2 expression is enriched in AR-independent advanced prostate cancer
CANCER RESEARCH
IF16.6
2023-06-021
PRE
Westaby, Daniel; Jimenez-Vacas, Juan M.; Figueiredo, Ines; Pettinger, Claire; Gurel, Bora; Bogdan, Denisa; Rekowski, Jan; Buroni, Lorenzo; Neeb, Antje; Riisnaes, Ruth; Crespo, Mateus; Miranda, Susana; Ferreira, Ana; Rodrigues, Daniel Nava; Seed, George; Bertan, Claudia; de la Maza, Maria de los Dolores Fenor; Guo, Christina; Carmichael, Juliet; Grochot, Rafael; Chandran, Khobe; Varkaris, Andreas; Balk, Steven P.; Yuan, Wei; Carreira, Suzanne; Nelson, Peter S.; Haffner, Michael; Corey, Eva; de Bono, Johann; Sharp, Adam
Distinct activity of androgen receptor splice variants in promoting prostate cancer metastasis
CANCER RESEARCH
IF16.6
2023-06-020
PRE
Labaf, Maryam; Han, Dong; Zhao, Yawei; Owiredu, Jude; Zhang, Songqi; Venkataramani, Kavita; Steinfeld, Jocelyn S.; Han, Wanting; Li, Muqing; Liu, Mingyu; Wang, Zifeng; Besschetnova, Anna; Patalano-Salsman, Susan C.; Macoska, Jill A.; Yuan, Xin; Balk, Steven P.; Plymate, Stephen R.; Gao, Shuai; Siegfried-Harris, Kellee R.; Liu, Ruihua; Foxa, Gabrielle; Stangis, Mary M.; Czernik, Piotr J.; Williams, Bart; Zarringhalam, Kourosh; Li, Xiaohong; Cai, Changmeng

研究方向

暂未获取到该数据
C
Changmeng Cai
H 指数:36论文数:193被引数:5,638
X
Xin Yuan
H 指数:35论文数:149被引数:6,628
S
Shaoyong Chen
H 指数:28论文数:106被引数:3,524
M
Mark A. Exley
H 指数:58论文数:226被引数:1.2万
J
Joshua W. Russo
H 指数:17论文数:120被引数:1,667
G
Glenn J. Bubley
H 指数:79论文数:428被引数:5.6万
M
Mary‐Ellen Taplin
H 指数:52论文数:677被引数:2.4万
H
Housheng Hansen He
H 指数:57论文数:445被引数:1.5万
A
Adam G. Sowalsky
H 指数:27论文数:410被引数:3,962
M
Myles Brown
H 指数:127论文数:913被引数:8.4万