未登录 Antithrombin-binding heparan sulfate is ubiquitously expressed in epithelial cells and suppresses pancreatic tumorigenesis 抗凝血酶结合肝素硫酸盐在上皮细胞中广泛表达，并抑制胰腺肿瘤发生 Clausen, Thomas Mandel; Weiss, Ryan J.; Tremblay, Jacob R.; Kellman, Benjamin P.; Coker, Joanna; Dworkin, Leo A.; Rodriguez, Jessica P.; Chang, Ivy M.; Chen, Timothy; Padala, Vikram; Karlsson, Richard; Song, Hyemin; Peck, Kristina L.; Ogawa, Satoshi; Sandoval, Daniel R.; Joshi, Hiren J.; Wang, Gaowei; Ferguson, L. Paige; Bhalerao, Nikita; Moores, Allison; Reya, Tannishtha; Sander, Maike; Caffrey, Thomas C.; Grem, Jean L.; Aicher, Alexandra; Heeschen, Christopher; Le, Dzung; Lewis, Nathan E.; Hollingsworth, Michael A.; Grandgenett, Paul M.; Bellis, Susan L.; Miller, Rebecca L.; Fuster, Mark M.; Dawson, David W.; Engle, Dannielle D.; Esko, Jeffrey D. 分享 收藏
The protein deacetylase SIRT2 exerts metabolic control over adaptive J3 cell proliferation 蛋白质去乙酰化酶SIRT2对适应性J3细胞增殖发挥代谢调控作用 Wortham, Matthew; Ramms, Bastian; Zeng, Chun; Benthuysen, Jacqueline R.; Sai, Somesh; Pollow, Dennis P.; Liu, Fenfen; Schlichting, Michael; Harrington, Austin R.; Liu, Bradley; Prakash, Thazha P.; Pirie, Elaine C.; Zhu, Han; Baghdasarian, Siyouneh; Lee, Sean T.; Ruthig, Victor A.; Wells, Kristen L.; Auwerx, Johan; Shirihai, Orian S.; Sander, Maike 分享 收藏
分享 收藏
分享 收藏
EU-LIFE charter of independent life science research institutes 欧盟-独立生命科学研究机构的生命宪章 Superti-Furga, Giulio; Agostinho, Marta; Bury, Jo; Cook, Simon; Durinx, Christine; Ender, Anita; van Luenen, Henri; Lund, Anders H.; Medema, Rene H.; Miaczynska, Marta; Nickel, Dorthe; Pelicci, Pier Giuseppe; Puisieux, Alain; Ripatti, Samuli; Sander, Maike; Schubeler, Dirk; Serrano, Luis; Sommer, Thomas; Sonne-Hansen, Katrine; Tomancak, Pavel; Vives, Joan; Vontas, John; Bettencourt-Dias, Monica 分享 收藏
A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction Bender, R. Hugh F.; ODonnell, Benjamen T.; Shergill, Bhupinder; Pham, Brittany Q.; Tahmouresie, Sima; Sanchez, Celeste N.; Juat, Damie J.; Hatch, Michaela M. S.; Shirure, Venktesh S.; Wortham, Matthew; Nguyen-Ngoc, Kim-Vy; Jun, Yesl; Gaetani, Roberto; Christman, Karen L.; Teyton, Luc; George, Steven C.; Sander, Maike; Hughes, Christopher C. W. 分享 收藏
Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding 骨形态发生蛋白 (BMP)-2诱导的 β 细胞功能障碍与组蛋白修饰和NeuroD1染色质结合减少有关 Urizar, Adriana Ibarra; Prause, Michala; Ingerslev, Lars Roed; Wortham, Matthew; Sui, Yinghui; Sander, Maike; Williams, Kristine; Barres, Romain; Larsen, Martin R.; Christensen, Gitte Lund; Billestrup, Nils 分享 收藏
Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes Wang, Gaowei; Chiou, Joshua; Zeng, Chun; Miller, Michael; Matta, Ileana; Han, Jee Yun; Kadakia, Nikita; Okino, Mei-Lin; Beebe, Elisha; Mallick, Medhavi; Camunas-Soler, Joan; dos Santos, Theodore; Dai, Xiao-Qing; Ellis, Cara; Hang, Yan; Kim, Seung K.; MacDonald, Patrick E.; Kandeel, Fouad R.; Preissl, Sebastian; Gaulton, Kyle J.; Sander, Maike 分享 收藏
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes Zhu, Han; Wang, Gaowei; Nguyen-Ngoc, Kim-Vy; Kim, Dongsu; Miller, Michael; Goss, Georgina; Kovsky, Jenna; Harrington, Austin R.; Saunders, Diane C.; Hopkirk, Alexander L.; Melton, Rebecca; Powers, Alvin C.; Preissl, Sebastian; Spagnoli, Francesca M.; Gaulton, Kyle J.; Sander, Maike 分享 收藏
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings ;(vol 72, pg 433, 2023) Mastracci, Teresa L.; Apte, Minoti; Amundadottir, Laufey T.; Alvarsson, Alexandra; Artandi, Steven; Bellin, Melena D.; Bernal-Mizrachi, Ernesto; Caicedo, Alejandro; Campbell-Thompson, Martha; Cruz-Monserrate, Zobeida; El Ouaamari, Abdelfattah; Gaulton, Kyle J.; Geisz, Andrea; Goodarzi, Mark O.; Hara, Manami; Hull-Meichle, Rebecca L.; Kleger, Alexander; Klein, Alison P.; Kopp, Janel L.; Kulkarni, Rohit N.; Muzumdar, Mandar D.; Naren, Anjaparavanda P.; Oakes, Scott A.; Olesen, Soren S.; Phelps, Edward A.; Powers, Alvin C.; Stabler, Cherie L.; Tirkes, Temel; Whitcomb, David C.; Yadav, Dhiraj; Yong, Jing; Zaghloul, Norann A.; Pandol, Stephen J.; Sander, Maike 分享 收藏
Nutrient regulation of the islet epigenome controls adaptive insulin secretion Wortham, Matthew; Liu, Fenfen; Harrington, Austin R.; Fleischman, Johanna Y.; Wallace, Martina; Mulas, Francesca; Mallick, Medhavi; Vinckier, Nicholas K.; Cross, Benjamin R.; Chiou, Joshua; Patel, Nisha A.; Sui, Yinghui; McGrail, Carolyn; Jun, Yesl; Wang, Gaowei; Jhala, Ulupi S.; Schuele, Roland; Shirihai, Orian S.; Huising, Mark O.; Gaulton, Kyle J.; Metallo, Christian M.; Sander, Maike 分享 收藏
Matters arising: Insufficient evidence that pancreatic b cells are derived from adult ductal Neurog3-expressing progenitors Magenheim, Judith; Maestro, Miguel Angel; Sharon, Nadav; Herrera, Pedro L.; Murtaugh, L. Charles; Kopp, Janel; Sander, Maike; Gu, Guoqiang; Melton, Douglas A.; Ferrer, Jorge; Dor, Yuval 分享 收藏
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings Mastracci, Teresa L.; Apte, Minoti; Amundadottir, Laufey T.; Alvarsson, Alexandra; Artandi, Steven; Bellin, Melena D.; Bernal-Mizrachi, Ernesto; Caicedo, Alejandro; Campbell-Thompson, Martha; Cruz-Monserrate, Zobeida; El Ouaamari, Abdelfattah; Gaulton, Kyle J.; Geisz, Andrea; Goodarzi, Mark O.; Hara, Manami; Hull-Meichle, Rebecca L.; Kleger, Alexander; Klein, Alison P.; Kopp, Janel L.; Kulkarni, Rohit N.; Muzumdar, Mandar D.; Naren, Anjaparavanda P.; Oakes, Scott A.; Olesen, Soren S.; Phelps, Edward A.; Powers, Alvin C.; Stabler, Cherie L.; Tirkes, Temel; Whitcomb, David C.; Yadav, Dhiraj; Yong, Jing; Zaghloul, Norann A.; Pandol, Stephen J.; Sander, Maike 分享 收藏
Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines Benaglio, Paola; Zhu, Han; Okino, Mei-Lin; Yan, Jian; Elgamal, Ruth; Nariai, Naoki; Beebe, Elisha; Korgaonkar, Katha; Qiu, Yunjiang; Donovan, Margaret K. R.; Chiou, Joshua; Wang, Gaowei; Newsome, Jacklyn; Kaur, Jaspreet; Miller, Michael; Preissl, Sebastian; Corban, Sierra; Aylward, Anthony; Taipale, Jussi; Ren, Bing; Frazer, Kelly A.; Sander, Maike; Gaulton, Kyle J. 分享 收藏
分享 收藏
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation 2型糖尿病的多血统遗传研究突出了不同人群发现和翻译的力量 Mahajan, Anubha; Spracklen, Cassandra N.; Zhang, Weihua; Ng, Maggie C. Y.; Petty, Lauren E.; Kitajima, Hidetoshi; Yu, Grace Z.; Rueger, Sina; Speidel, Leo; Kim, Young Jin; Horikoshi, Momoko; Mercader, Josep M.; Taliun, Daniel; Moon, Sanghoon; Kwak, Soo-Heon; Robertson, Neil R.; Rayner, Nigel W.; Loh, Marie; Kim, Bong-Jo; Chiou, Joshua; Miguel-Escalada, Irene; Parolo, Pietro della Briotta; Lin, Kuang; Bragg, Fiona; Preuss, Michael H.; Takeuchi, Fumihiko; Nano, Jana; Guo, Xiuqing; Lamri, Amel; Nakatochi, Masahiro; Scott, Robert A.; Lee, Jung-Jin; Huerta-Chagoya, Alicia; Graff, Mariaelisa; Chai, Jin-Fang; Parra, Esteban J.; Yao, Jie; Bielak, Lawrence F.; Tabara, Yasuharu; Hai, Yang; Steinthorsdottir, Valgerdur; Cook, James P.; Kals, Mart; Grarup, Niels; Schmidt, Ellen M.; Pan, Ian; Sofer, Tamar; Wuttke, Matthias; Sarnowski, Chloe; Gieger, Christian; Nousome, Darryl; Trompet, Stella; Long, Jirong; Sun, Meng; Tong, Lin; Chen, Wei-Min; Ahmad, Meraj; Noordam, Raymond; Lim, Victor J. Y.; Tam, Claudia H. T.; Joo, Yoonjung Yoonie; Chen, Chien-Hsiun; Raffield, Laura M.; Lecoeur, Cecile; Prins, Bram Peter; Nicolas, Aude; Yanek, Lisa R.; Chen, Guanjie; Jensen, Richard A.; Tajuddin, Salman; Kabagambe, Edmond K.; An, Ping; Xiang, Anny H.; Choi, Hyeok Sun; Cade, Brian E.; Tan, Jingyi; Flanagan, Jack; Abaitua, Fernando; Adair, Linda S.; Adeyemo, Adebowale; Aguilar-Salinas, Carlos A.; Akiyama, Masato; Anand, Sonia S.; Bertoni, Alain; Bian, Zheng; Bork-Jensen, Jette; Brandslund, Ivan; Brody, Jennifer A.; Brummett, Chad M.; Buchanan, Thomas A.; Canouil, Mickael; Chan, Juliana C. N.; Chang, Li-Ching; Chee, Miao-Li; Chen, Ji; Chen, Shyh-Huei; Chen, Yuan-Tsong; Chen, Zhengming; Chuang, Lee-Ming; Cushman, Mary; Das, Swapan K.; de Silva, H. Janaka; Dedoussis, George; Dimitrov, Latchezar; Doumatey, Ayo P.; Du, Shufa; Duan, Qing; Eckardt, Kai-Uwe; Emery, Leslie S.; Evans, Daniel S.; Evans, Michele K.; Fischer, Krista; Floyd, James S.; Ford, Ian; Fornage, Myriam; Franco, Oscar H.; Frayling, Timothy M.; Freedman, Barry, I; Fuchsberger, Christian; Genter, Pauline; Gerstein, Hertzel C.; Giedraitis, Vilmantas; Gonzalez-Villalpando, Clicerio; Gonzalez-Villalpando, Maria Elena; Goodarzi, Mark O.; Gordon-Larsen, Penny; Gorkin, David; Gross, Myron; Guo, Yu; Hackinger, Sophie; Han, Sohee; Hattersley, Andrew T.; Herder, Christian; Howard, Annie-Green; Hsueh, Willa; Huang, Mengna; Huang, Wei; Hung, Yi-Jen; Hwang, Mi Yeong; Hwu, Chii-Min; Ichihara, Sahoko; Ikram, Mohammad Arfan; Ingelsson, Martin; Islam, Md Tariqul; Isono, Masato; Jang, Hye-Mi; Jasmine, Farzana; Jiang, Guozhi; Jonas, Jost B.; Jorgensen, Marit E.; Jorgensen, Torben; Kamatani, Yoichiro; Kandeel, Fouad R.; Kasturiratne, Anuradhani; Katsuya, Tomohiro; Kaur, Varinderpal; Kawaguchi, Takahisa; Keaton, Jacob M.; Kho, Abel N.; Khor, Chiea-Chuen; Kibriya, Muhammad G.; Kim, Duk-Hwan; Kohara, Katsuhiko; Kriebel, Jennifer; Kronenberg, Florian; Kuusisto, Johanna; Lall, Kristi; Lange, Leslie A.; Lee, Myung-Shik; Lee, Nanette R.; Leong, Aaron; Li, Liming; Li, Yun; Li-Gao, Ruifang; Ligthart, Symen; Lindgren, Cecilia M.; Linneberg, Allan; Liu, Ching-Ti; Liu, Jianjun; Locke, Adam E.; Louie, Tin; Luan, Jian'an; Luk, Andrea O.; Luo, Xi; Lv, Jun; Lyssenko, Valeriya; Mamakou, Vasiliki; Mani, K. Radha; Meitinger, Thomas; Metspalu, Andres; Morris, Andrew D.; Nadkarni, Girish N.; Nadler, Jerry L.; Nalls, Michael A.; Nayak, Uma; Nongmaithem, Suraj S.; Ntalla, Ioanna; Okada, Yukinori; Orozco, Lorena; Patel, Sanjay R.; Pereira, Mark A.; Peters, Annette; Pirie, Fraser J.; Porneala, Bianca; Prasad, Gauri; Preissl, Sebastian; Rasmussen-Torvik, Laura J.; Reiner, Alexander P.; Roden, Michael; Rohde, Rebecca; Roll, Kathryn; Sabanayagam, Charumathi; Sander, Maike; Sandow, Kevin; Sattar, Naveed; Schonherr, Sebastian; Schurmann, Claudia; Shahriar, Mohammad; Shi, Jinxiu; Shin, Dong Mun; Shriner, Daniel; Smith, Jennifer A.; So, Wing Yee; Stancakova, Alena; Stilp, Adrienne M.; Strauch, Konstantin; Suzuki, Ken; Takahashi, Atsushi; Taylor, Kent D.; Thorand, Barbara; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tomlinson, Brian; Torres, Jason M.; Tsai, Fuu-Jen; Tuomilehto, Jaakko; Tusie-Luna, Teresa; Udler, Miriam S.; Valladares-Salgado, Adan; van Dam, Rob M.; van Klinken, Jan B.; Varma, Rohit; Vujkovic, Marijana; Wacher-Rodarte, Niels; Wheeler, Eleanor; Whitsel, Eric A.; Wickremasinghe, Ananda R.; van Dijk, Ko Willems; Witte, Daniel R.; Yajnik, Chittaranjan S.; Yamamoto, Ken; Yamauchi, Toshimasa; Yengo, Loic; Yoon, Kyungheon; Yu, Canqing; Yuan, Jian-Min; Yusuf, Salim; Zhang, Liang; Zheng, Wei; Raffel, Leslie J.; Igase, Michiya; Ipp, Eli; Redline, Susan; Cho, Yoon Shin; Lind, Lars; Province, Michael A.; Hanis, Craig L.; Peyser, Patricia A.; Ingelsson, Erik; Zonderman, Alan B.; Psaty, Bruce M.; Wang, Ya-Xing; Rotimi, Charles N.; Becker, Diane M.; Matsuda, Fumihiko; Liu, Yongmei; Zeggini, Eleftheria; Yokota, Mitsuhiro; Rich, Stephen S.; Kooperberg, Charles; Pankow, James S.; Engert, James C.; Chen, Yii-Der Ida; Froguel, Philippe; Wilson, James G.; Sheu, Wayne H. H.; Kardia, Sharon L. R.; Wu, Jer-Yuarn; Hayes, M. Geoffrey; Ma, Ronald C. W.; Wong, Tien-Yin; Groop, Leif; Mook-Kanamori, Dennis O.; Chandak, Giriraj R.; Collins, Francis S.; Bharadwaj, Dwaipayan; Pare, Guillaume; Sale, Michele M.; Ahsan, Habibul; Motala, Ayesha A.; Shu, Xiao-Ou; Park, Kyong-Soo; Jukema, J. Wouter; Cruz, Miguel; McKean-Cowdin, Roberta; Grallert, Harald; Cheng, Ching-Yu; Bottinger, Erwin P.; Dehghan, Abbas; Tai, E-Shyong; Dupuis, Josee; Kato, Norihiro; Laakso, Markku; Kottgen, Anna; Koh, Woon-Puay; Palmer, Colin N. A.; Liu, Simin; Abecasis, Goncalo; Kooner, Jaspal S.; Loos, Ruth J. F.; North, Kari E.; Haiman, Christopher A.; Florez, Jose C.; Saleheen, Danish; Hansen, Torben; Pedersen, Oluf; Magi, Reedik; Langenberg, Claudia; Wareham, Nicholas J.; Maeda, Shiro; Kadowaki, Takashi; Lee, Juyoung; Millwood, Iona Y.; Walters, Robin G.; Stefansson, Kari; Myers, Simon R.; Ferrer, Jorge; Gaulton, Kyle J.; Meigs, James B.; Mohlke, Karen L.; Gloyn, Anna L.; Bowden, Donald W.; Below, Jennifer E.; Chambers, John C.; Sim, Xueling; Boehnke, Michael; Rotter, Jerome, I; McCarthy, Mark, I; Morris, Andrew P. 分享 收藏
分享 收藏
Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance Shum, Michael; Segawa, Mayuko; Gharakhanian, Raffi; Vinuela, Ana; Wortham, Matthew; Baghdasarian, Siyouneh; Wolf, Dane M.; Sereda, Samuel B.; Nocito, Laura; Stiles, Linsey; Zhou, Zhiqiang; Gutierrez, Vincent; Sander, Maike; Shirihai, Orian S.; Liesa, Marc 分享 收藏
Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation Heller, Sandra; Li, Zhijian; Lin, Qiong; Geusz, Ryan; Breunig, Markus; Hohwieler, Meike; Zhang, Xi; Nair, Gopika G.; Seufferlein, Thomas; Hebrok, Matthias; Sander, Maike; Julier, Cecile; Kleger, Alexander; Costa, Ivan G. 分享 收藏
Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors Geusz, Ryan J.; Wang, Allen; Lam, Dieter K.; Vinckier, Nicholas K.; Alysandratos, Konstantinos-Dionysios; Roberts, David A.; Wang, Jinzhao; Kefalopoulou, Samy; Ramirez, Araceli; Qiu, Yunjiang; Chiou, Joshua; Gaulton, Kyle J.; Ren, Bing; Kotton, Darrell N.; Sander, Maike 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
