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CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase Krysiak, Kilannin; Danos, Arpad M.; Saliba, Jason; McMichael, Joshua F.; Coffman, Adam C.; Kiwala, Susanna; Barnell, Erica K.; Sheta, Lana; Grisdale, Cameron J.; Kujan, Lynzey; Pema, Shahil; Lever, Jake; Ridd, Sarah; Spies, Nicholas C.; Andric, Veronica; Chiorean, Andreea; Rieke, Damian T.; Clark, Kaitlin A.; Reisle, Caralyn; Venigalla, Ajay C.; Evans, Mark; Jani, Payal; Takahashi, Hideaki; Suda, Avila; Horak, Peter; Ritter, Deborah, I; Zhou, Xin; Ainscough, Benjamin J.; Delong, Sean; Kesserwan, Chimene; Lamping, Mario; Shen, Haolin; Marr, Alex R.; Hoang, My H.; Singhal, Kartik; Khanfar, Mariam; Li, Brian, V; Lin, Wan-Hsin; Terraf, Panieh; Corson, Laura B.; Salama, Yasser; Campbell, Katie M.; Farncombe, Kirsten M.; Ji, Jianling; Zhao, Xiaonan; Xu, Xinjie; Kanagal-Shamanna, Rashmi; King, Ian; Cotto, Kelsy C.; Skidmore, Zachary L.; Walker, Jason R.; Zhang, Jinghui; Milosavljevic, Aleksandar; Patel, Ronak Y.; Giles, Rachel H.; Kim, Raymond H.; Schriml, Lynn M.; Mardis, Elaine R.; Jones, Steven J. M.; Raca, Gordana; Rao, Shruti; Madhavan, Subha; Wagner, Alex H.; Griffith, Malachi; Griffith, Obi L. 分享 收藏
Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer Church, Alanna J.; Corson, Laura B.; Kao, Pei-Chi; Imamovic-Tuco, Alma; Reidy, Deirdre; Doan, Duong; Kang, Wenjun; Pinto, Navin; Maese, Luke; Laetsch, Theodore W.; Kim, AeRang; Colace, Susan I.; Macy, Margaret E.; Applebaum, Mark A.; Bagatell, Rochelle; Sabnis, Amit J.; Weiser, Daniel A.; Glade-Bender, Julia L.; Homans, Alan C.; Hipps, John; Harris, Haley; Manning, Danielle; Al-Ibraheemi, Alyaa; Li, Yvonne; Gupta, Hersh; Cherniack, Andrew D.; Lo, Ying-Chun; Strand, Gianna R.; Lee, Lobin A.; Pinches, R. Seth; Lazo De La Vega, Lorena; Harden, Maegan V.; Lennon, Niall J.; Choi, Seong; Comeau, Hannah; Harris, Marian H.; Forrest, Suzanne J.; Clinton, Catherine M.; Crompton, Brian D.; Kamihara, Junne; MacConaill, Laura E.; Volchenboum, Samuel L.; Lindeman, Neal I.; Van Allen, Eliezer; DuBois, Steven G.; London, Wendy B.; Janeway, Katherine A. 分享 收藏
Genetic variants associated with childhood cancers: Curation initiatives of the ClinGen Somatic Cancer Pediatric Taskforce Williams, Heather; Krysiak, Kilannin; Lin, Wan-Hsin; Roy, Angshumoy; Church, Alanna; Saliba, Jason; Rao, Shruti; Ritter, Deborah; Danos, Arpad; Corson, Laura; Fisher, Kevin; Hiemenz, Matthew; Janeway, Katherine A.; Ji, Jianling; Kesserwan, Chimene; Laetsch, Ted; Parsons, Donald; Schmidt, Ryan; Sund, Kristen; Terraf, Panieh; Xu, Xinjie; Kanagal-Shamana, Rashmi; Dyer, Lisa; Harris, Marian; Lee, Kristy; Wagner, Alex; Akkari, Yassmine; Satgunaseelan, Laveniya; Griffith, Malachi; Griffith, Obi; Kulkarni, Shashikant; Schriml, Lynn; Jean, Jeffrey; Madhavan, Subha; Raca, Gordana 分享 收藏
Sensitivity to splicing modulation of BCL2 family genes reveals cancer therapeutic strategies for splicing modulators Aird, Daniel; Teng, Teng; Huang, Chia-Ling; Pazolli, Ermira; Banka, Deepti; Cheung-Ong, Kahlin; Eifert, Cheryl; Furman, Craig; Wu, Jeremy; Seiler, Michael; Buonamici, Silvia; Fekkes, Peter; Karr, Craig; Palacino, James; Park, Eunice; Smith, Peter; Yu, Lihua; Mizui, Yoshiharu; Warmuth, Markus; Chicas, Agustin; Corson, Laura; Zhu, Ping 分享 收藏
A high prevalence of chromosomal translocations as drivers in high-risk pediatric solid cancers Corson, Laura B.; Imamovic-Tuco, Alma; Strand, Gianna R.; Reidy, Deirdre; Doan, Duong; Applebaum, Mark A.; Bagatell, Rochelle; Crompton, Brian D.; DuBois, Steven G.; Bender, Julia L. Glade; Kim, AeRang; Laetsch, Theodore W.; Lee, Lobin A.; Lindeman, Neal I.; MacConaill, Laura E.; Macy, Margaret E.; Maese, Luke; Pinches, Seth; Pinto, Navin; Sabnis, Amit J.; Van Allen, Eliezer M.; Vear, Susan I.; Weiser, Daniel A.; Clinton, Catherine M.; Janeway, Katherine A.; Church, Alanna J. 分享 收藏
Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer (vol 8, 103, 2017) Korpal, Manav; Puyang, Xiaoling; Wu, Zhenhua Jeremy; Seiler, Roland; Furman, Craig; Oo, Htoo Zarni; Seiler, Michael; Irwin, Sean; Subramanian, Vanitha; Joshi, Jaya Julie; Wang, Chris K.; Rimkunas, Victoria; Tortora, Davide; Yang, Hua; Kumar, Namita; Kuznetsov, Galina; Matijevic, Mark; Chow, Jesse; Kumar, Pavan; Zou, Jian; Feala, Jacob; Corson, Laura; Henry, Ryan; Selvaraj, Anand; Davis, Allison; Bloudoff, Kristjan; Douglas, James; Kiss, Bernhard; Roberts, Morgan; Fazli, Ladan; Black, Peter C.; Fekkes, Peter; Smith, Peter G.; Warmuth, Markus; Yu, Lihua; Hao, Ming-Hong; Larsen, Nicholas; Daugaard, Mads; Zhu, Ping 分享 收藏
Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators Aird, Daniel; Teng, Teng; Huang, Chia-Ling; Pazolli, Ermira; Banka, Deepti; Cheung-Ong, Kahlin; Eifert, Cheryl; Furman, Craig; Wu, Zhenhua Jeremy; Seiler, Michael; Buonamici, Silvia; Fekkes, Peter; Karr, Craig; Palacino, James; Park, Eunice; Smith, Peter G.; Yu, Lihua; Mizui, Yoshiharu; Warmuth, Markus; Chicas, Agustin; Corson, Laura; Zhu, Ping 分享 收藏
Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer Korpal, Manav; Puyang, Xiaoling; Wu, Zhenhua Jeremy; Seiler, Roland; Furman, Craig; Oo, Htoo Z.; Seiler, Michael; Irwin, Sean; Subramanian, Vanitha; Joshi, Jaya Julie; Wang, Chris K.; Rimkunas, Victoria; Tortora, Davide; Yang, Hua; Kumar, Namita; Kuznetsov, Galina; Matijevic, Mark; Chow, Jesse; Kumar, Pavan; Zou, Jian; Feala, Jacob; Corson, Laura; Henry, Ryan; Selvaraj, Anand; Davis, Allison; Bloudoff, Kristjan; Douglas, James; Kiss, Bernhard; Roberts, Morgan; Fazli, Ladan; Black, Peter C.; Fekkes, Peter; Smith, Peter G.; Warmuth, Markus; Yu, Lihua; Hao, Ming-Hong; Larsen, Nicholas; Daugaard, Mads; Zhu, Ping 分享 收藏
A chemogenomic approach reveals the action of splicing modulators at the branch point adenosine binding pocket defined by the PHF5A/SF3b complex Teng, Teng; Tsai, Jennifer; Puyang, Xiaoling; Seiler, Michael; Peng, Shouyong; Aird, Daniel; Buonamici, Silvia; Caleb, Benjamin; Chan, Betty; Corson, Laura; Feala, Jacob; Fekkes, Peter; Karr, Craig; Korpal, Manav; Mizui, Yoshiharu; Park, Eunice; Palacino, James; Smith, Peter; Subramanian, Vanitha; Wu, Jeremy; Yu, Lihua; Chicas, Agustin; Warmuth, Markus; Larsen, Nicholas; Zhu, Ping 分享 收藏
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex Teng, Teng; Tsai, Jennifer H. C.; Puyang, Xiaoling; Seiler, Michael; Peng, Shouyong; Prajapati, Sudeep; Aird, Daniel; Buonamici, Silvia; Caleb, Benjamin; Chan, Betty; Corson, Laura; Feala, Jacob; Fekkes, Peter; Gerard, Baudouin; Karr, Craig; Korpal, Manav; Liu, Xiang; Lowe, Jason T.; Mizui, Yoshiharu; Palacino, James; Park, Eunice; Smith, Peter G.; Subramanian, Vanitha; Wu, Zhenhua Jeremy; Zou, Jian; Yu, Lihua; Chicas, Agustin; Warmuth, Markus; Larsen, Nicholas; Zhu, Ping 分享 收藏
Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice Purkey, Hans E.; Robarge, Kirk; Chen, Jinhua; Chen, Zhongguo; Corson, Laura B.; Ding, Charles Z.; DiPasquale, Antonio G.; Dragovich, Peter S.; Eigenbrot, Charles; Evangelista, Marie; Fauber, Benjamin P.; Gao, Zhenting; Ge, Hongxiu; Hitz, Anna; Ho, Qunh; Labadie, Sharada S.; Lai, Kwong Wah; Liu, Wenfeng; Liu, Yajing; Li, Chiho; Ma, Shuguang; Malek, Shiva; O'Brien, Thomas; Pang, Jodie; Peterson, David; Salphati, Laurent; Sideris, Steve; Ultsch, Mark; Wei, BinQing; Yen, Ivana; Yue, Qin; Zhang, Huihui; Zhou, Aihe 分享 收藏
Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition Boudreau, Aaron; Purkey, Hans E.; Hitz, Anna; Robarge, Kirk; Peterson, David; Labadie, Sharada; Kwong, Mandy; Hong, Rebecca; Gao, Min; Del Nagro, Christopher; Pusapati, Raju; Ma, Shuguang; Salphati, Laurent; Pang, Jodie; Zhou, Aihe; Lai, Tommy; Li, Yingjie; Chen, Zhongguo; Wei, Binqing; Yen, Ivana; Sideris, Steve; McCleland, Mark; Firestein, Ron; Corson, Laura; Vanderbilt, Alex; Williams, Simon; Daemen, Anneleen; Belvin, Marcia; Eigenbrot, Charles; Jackson, Peter K.; Malek, Shiva; Hatzivassiliou, Georgia; Sampath, Deepak; Evangelista, Marie; O'Brien, Thomas 分享 收藏
Identification of PHF5A as a common cellular target of splicing-modulating chemical probes Teng, Teng; Puyang, Xiaoling; Peng, Shouyong; Feala, Jacob; Chan, Betty; Tsai, Jennifer; Caleb, Benjamin; Karr, Craig; Park, Eunice; Corson, Laura; Mizui, Yoshiharu; Smith, Peter; Larsen, Nicholas; Yu, Lihua; Warmuth, Markus; Zhu, Ping; Chicas, Agustin 分享 收藏
Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point 癌症相关的SF3B1热点突变通过使用不同的分支点诱导隐蔽的3' 剪接位点选择 Darman, Rachel B.; Seiler, Michael; Agrawal, Anant A.; Lim, Kian H.; Peng, Shouyong; Aird, Daniel; Bailey, Suzanna L.; Bhavsar, Erica B.; Chan, Betty; Colla, Simona; Corson, Laura; Feala, Jacob; Fekkes, Peter; Ichikawa, Kana; Keaney, Gregg F.; Lee, Linda; Kumar, Pavan; Kunii, Kaiko; MacKenzie, Crystal; Matijevic, Mark; Mizui, Yoshiharu; Myint, Khin; Park, Eun Sun; Puyang, Xiaoling; Selvaraj, Anand; Thomas, Michael P.; Tsai, Jennifer; Wang, John Y.; Warmuth, Markus; Yang, Hui; Zhu, Ping; Garcia-Manero, Guillermo; Furman, Richard R.; Yu, Lihua; Smith, Peter G.; Buonamici, Silvia 分享 收藏
Targeting MCL1-dependent cancers through RNA splicing modulation Park, Eun Sun; Aicher, Michelle; Aird, Daniel; Buonamici, Silvia; Chan, Betty; Eifert, Cheryl; Fekkes, Peter; Furman, Craig; Gerard, Baudouin; Karr, Craig; Keaney, Gregg; Kunii, Kaiko; Lee, Linda; Pazolli, Ermira; Prajapati, Sudeep; Satoh, Takashi; Smith, Peter; Wang, John Yuan; Wang, Karen; Warmuth, Markus; Yu, Lihua; Zhu, Ping; Mizui, Yoshiharu; Corson, Laura B. 分享 收藏
Total synthesis of 6-deoxypladienolide D and assessment of splicing inhibitory activity in a mutant SF3B1 cancer cell line Arai, Kenzo; Buonamici, Silvia; Chan, Betty; Corson, Laura; Endo, Atsushi; Gerard, Baudouin; Hao, Ming-Hong; Karr, Craig; Kira, Kazunobu; Lee, Linda; Liu, Xiang; Lowe, Jason T.; Luo, Tuoping; Marcaurelle, Lisa A.; Mizui, Yoshiharu; Nevalainen, Marta; O'Shea, Morgan Welzel; Park, Eun Sun; Perino, Samantha A.; Prajapati, Sudeep; Shan, Mingde; Smith, Peter G.; Tivitmahaisoon, Parcharee; Wang, John Yuan; Warmuth, Markus; Wu, Kuo-Ming; Yu, Lihua; Zhang, Huiming; Zheng, Guo Zhu; Keaney, Gregg F. 分享 收藏
Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors 代谢物谱分析将胰腺导管腺癌分层为对代谢抑制剂具有不同敏感性的亚型 Daemen, Anneleen; Peterson, David; Sahu, Nisebita; McCord, Ron; Du, Xiangnan; Liu, Bonnie; Kowanetz, Katarzyna; Hong, Rebecca; Moffat, John; Gao, Min; Boudreau, Aaron; Mroue, Rana; Corson, Laura; O'Brien, Thomas; Qing, Jing; Sampath, Deepak; Merchant, Mark; Yauch, Robert; Manning, Gerard; Settleman, Jeffrey; Hatzivassiliou, Georgia; Evangelista, Marie 分享 收藏
A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3 Lahtela, Jenni; Corson, Laura B.; Hemmes, Annabrita; Brauer, Matthew J.; Koopal, Sonja; Lee, James; Hunsaker, Thomas L.; Jackson, Peter K.; Verschuren, Emmy W. 分享 收藏
Total Synthesis of 6-Deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 Cancer Cell Line Arai, Kenzo; Buonamici, Silvia; Chan, Betty; Corson, Laura; Endo, Atsushi; Gerard, Baudouin; Hao, Ming-Hong; Karr, Craig; Kira, Kazunobu; Lee, Linda; Liu, Xiang; Lowe, Jason T.; Luo, Tuoping; Marcaurelle, Lisa A.; Mizui, Yoshiharu; Nevalainen, Marta; O'Shea, Morgan Welzel; Park, Eun Sun; Perino, Samantha A.; Prajapati, Sudeep; Shan, Mingde; Smith, Peter G.; Tivitmahaisoon, Parcharee; Wang, John Yuan; Warmuth, Markus; Wu, Kuo-Ming; Yu, Lihua; Zhang, Huiming; Zheng, Guo-Zhu; Keaney, Gregg F. 分享 收藏
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