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收藏分享 收藏 分享 收藏 HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains
Kamada, Yuka; Ohnishi, Yuko; Nakashima, Chikako; Fujii, Aika; Terakawa, Mana; Hamano, Ikuto; Nakayamada, Uta; Katoh, Saori; Hirata, Noriaki; Tateishi, Hazuki; Fukuda, Ryosuke; Takahashi, Hirotaka; Lukacs, Gergely L.; Okiyoneda, Tsukasa 分享 收藏 Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain couplingSoya, Naoto; Xu, Haijin; Roldan, Ariel; Yang, Zhengrong; Ye, Haoxin; Jiang, Fan; Premchandar, Aiswarya; Veit, Guido; Cole, Susan P. C.; Kappes, John; Hegedus, Tamas; Lukacs, Gergely L. 分享 收藏 Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathwayVarghese, Bentley; Barriere, Herve; Carbone, Christopher J.; Banerjee, Anamika; Swaminathan, Gayathri; Plotnikov, Alexander; Xu, Ping; Peng, Junmin; Goffin, Vincent; Lukacs, Gergely L.; Fuchs, Serge Y. 分享 收藏 Keratin 8 is a scaffolding and regulatory protein of ERAD complexesPranke, Iwona Maria; Chevalier, Benoit; Premchandar, Aiswarya; Baatallah, Nesrine; Tomaszewski, Kamil F.; Bitam, Sara; Tondelier, Danielle; Golec, Anita; Stolk, Jan; Lukacs, Gergely L.; Hiemstra, Pieter S.; Dadlez, Michal; Lomas, David A.; Irving, James A.; Delaunay-Moisan, Agnes; van Anken, Eelco; Hinzpeter, Alexandre; Sermet-Gaudelus, Isabelle; Edelman, Aleksander 分享 收藏 A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseasesPI3Kγ 模拟肽触发CFTR门控，支气管扩张和减轻阻塞性气道疾病的炎症Ghigo, Alessandra; Murabito, Alessandra; Sala, Valentina; Pisano, Anna Rita; Bertolini, Serena; Gianotti, Ambra; Caci, Emanuela; Montresor, Alessio; Premchandar, Aiswarya; Pirozzi, Flora; Ren, Kai; Della Sala, Angela; Mergiotti, Marco; Richter, Wito; de Poel, Eyleen; Matthey, Michaela; Caldrer, Sara; Cardone, Rosa A.; Civiletti, Federica; Costamagna, Andrea; Quinney, Nancy L.; Butnarasu, Cosmin; Visentin, Sonja; Ruggiero, Maria Rosaria; Baroni, Simona; Crich, Simonetta Geninatti; Ramel, Damien; Laffargue, Muriel; Tocchetti, Carlo G.; Levi, Renzo; Conti, Marco; Lu, Xiao-Yun; Melotti, Paola; Sorio, Claudio; De Rose, Virginia; Facchinetti, Fabrizio; Fanelli, Vito; Wenzel, Daniela; Fleischmann, Bernd K.; Mall, Marcus A.; Beekman, Jeffrey; Laudanna, Carlo; Gentzsch, Martina; Lukacs, Gergely L.; Pedemonte, Nicoletta; Hirsch, Emilio 分享 收藏 Ubr1-induced selective endophagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stressWang, Ben B.; Xu, Haijin; Isenmann, Sandra; Huang, Cheng; Elorza-Vidal, Xabier; Rychkov, Grigori Y.; Estevez, Raul; Schittenhelm, Ralf B.; Lukacs, Gergely L.; Apaja, Pirjo M. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combinationVeit, Guido; Roldan, Ariel; Hancock, Mark A.; Da Fonte, Dillon F.; Xu, Haijin; Hussein, Maytham; Frenkiel, Saul; Matouk, Elias; Velkov, Tony; Lukacs, Gergely L. 分享 收藏 分享 收藏 Mutation-specific dual potentiators maximize rescue of CFTR gating mutantsVeit, Guido; Da Fonte, Dillon F.; Avramescu, Radu G.; Premchandar, Aiswarya; Bagdany, Miklos; Xu, Haijin; Bensinger, Dennis; Stubba, Daniel; Schmidt, Boris; Matouk, Elias; Lukacs, Gergely L. 分享 收藏 High-throughput phenotyping of heteromeric human ether-a-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variantsNg, Chai-Ann; Perry, Matthew D.; Liang, Whitney; Smith, Nicola J.; Foo, Brian; Shrier, Alvin; Lukacs, Gergely L.; Hill, Adam P.; Vandenberg, Jamie, I 分享 收藏 分享 收藏 Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and ActivityArmirotti, Andrea; Tomati, Valeria; Matthes, Elizabeth; Veit, Guido; Cholon, Deborah M.; Phuan, Puay-Wah; Braccia, Clarissa; Guidone, Daniela; Gentzsch, Martina; Lukacs, Gergely L.; Verkman, Alan S.; Galietta, Luis J., V; Hanrahan, John W.; Pedemonte, Nicoletta 分享 收藏 
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