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A

Ariel Roldán

pennsylvania commonwealth system of higher education (pcshe)

H指数:18

被引数:1,844

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Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling

NATURE COMMUNICATIONS

IF15.7

2023-10-278

OAAI

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination

IF6.1

2020-09-17168

OA

Structure-guided combination therapy to potently improve the function of mutant CFTRs

NATURE MEDICINE

IF50

2018-10-08110

OAAI

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell

NATURE COMMUNICATIONS

IF15.7

2017-08-3064

OAAI

Development and characterization of synthetic antibodies binding to the cystic fibrosis conductance regulator

IF7.3

2016-05-164

OA

Non-native Conformers of Cystic Fibrosis Transmembrane Conductance Regulator NBD1 Are Recognized by Hsp27 and Conjugated to SUMO-2 for Degradation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-01-0130

OAAI

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

IF6.9

2015-10-0159

OAAI

Synergy-Based Small-Molecule Screen Using a Human Lung Epithelial Cell Line Yields ΔF508-CFTR Correctors That Augment VX-809 Maximal Efficacy

MOLECULAR PHARMACOLOGY

IF3

2014-07-0166

OAAI

Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain

EMBO MOLECULAR MEDICINE

IF8.3

2013-08-2778

OAAI

Mechanism-based corrector combination restores ΔF508-CFTR folding and function

NATURE CHEMICAL BIOLOGY

IF13.7

2013-05-12386

OA

A HIV-1 minimal gag protein is superior to nucleocapsid at in vitro tRNA3Lys annealing and exhibits multimerization-induced inhibition of reverse transcription

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2005-04-0129

OAAI

Mutation of the SP1 sequence impairs both multimerization and membrane-binding activities of human immunodeficiency virus type 1 Gag

JOURNAL OF VIROLOGY

IF3.8

2005-02-0159

OAAI

In vitro identification and characterization of an early complex linking HIV-1 genomic RNA recognition and Pr55Gag multimerization

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2004-09-0136

OAAI

Effects of a single amino acid substitution within the p2 region of human immunodeficiency virus type 1 on packaging of spliced viral RNA

JOURNAL OF VIROLOGY

IF3.8

2003-12-1541

OAAI

Characterization of a putative α-helix across the capsid-SP1 boundary that is critical for the multimerization of human immunodeficiency virus type 1 gag

JOURNAL OF VIROLOGY

IF3.8

2002-11-15109

OAAI

Molecular characterization of beta-thalassemia genes in an Argentine population

阿根廷人群中 β-地中海贫血基因的分子特征

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

1997-03-0121

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