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G

Guido Veit

mcgill university

H指数:28

被引数:3,619

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Synthesis and Biological Evaluation of Pyrazole-Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-08-130

PRE

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling

NATURE COMMUNICATIONS

IF15.7

2023-10-278

OAAI

Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2022-07-120

OAAI

Elexacaftor co-potentiates the activity of F508del and gating mutants of CFTR

JOURNAL OF CYSTIC FIBROSIS

IF6

2021-09-0157

OAAI

A Precision Medicine Approach to Optimize Modulator Therapy for Rare CFTR Folding Mutants

JOURNAL OF PERSONALIZED MEDICINE

IF3

2021-07-0722

OAAI

Discovery of CFTR modulators for the treatment of cystic fibrosis

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2021-04-1350

PREAI

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination

IF6.1

2020-09-17168

OA

Mutation-specific dual potentiators maximize rescue of CFTR gating mutants

JOURNAL OF CYSTIC FIBROSIS

IF6

2020-03-0130

OAAI

Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity

SCIENTIFIC REPORTS

IF3.9

2019-07-168

OAAI

Transcytosis maintains CFTR apical polarity in the face of constitutive and mutation-induced basolateral missorting

JOURNAL OF CELL SCIENCE

IF3.6

2019-05-157

OAAI

Structure-guided combination therapy to potently improve the function of mutant CFTRs

NATURE MEDICINE

IF50

2018-10-08110

OAAI

Extracellular oxidation in cystic fibrosis airway epithelium causes enhanced EGFR/ADAM17 activity

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2018-04-0116

OAAI

Chaperone-Independent Peripheral Quality Control of CFTR by RFFL E3 Ligase

DEVELOPMENTAL CELL

IF8.7

2018-03-0162

OAAI

Mutation-specific downregulation of CFTR2 variants by gating potentiators

HUMAN MOLECULAR GENETICS

IF3.2

2017-10-0442

OAAI

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell

NATURE COMMUNICATIONS

IF15.7

2017-08-3064

OAAI

Epithelial Anion Transport as Modulator of Chemokine Signaling

MEDIATORS OF INFLAMMATION

IF4.2

2016-01-019

OAAI

Potentiators of Defective ΔF508-CFTR Gating that Do Not Interfere with Corrector Action

MOLECULAR PHARMACOLOGY

IF3

2015-10-0138

OAAI

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2014-07-23286

OAAI

Synergy-Based Small-Molecule Screen Using a Human Lung Epithelial Cell Line Yields ΔF508-CFTR Correctors That Augment VX-809 Maximal Efficacy

MOLECULAR PHARMACOLOGY

IF3

2014-07-0166

OAAI

Collagen XXII binds to collagen-binding integrins via the novel motifs GLQGER and GFKGER

BIOCHEMICAL JOURNAL

IF4.3

2014-03-1426

PREAI