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A

Ashley M. Jacobi

integrated dna technologies
H指数:21
被引数:3,532

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Author Correction: UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems

作者更正：UNCOVERseq实现了对CRISPR-Cas模态和系统中敏感且可控的基因编辑脱靶位点的鉴定

Nature Communications
IF15.7
2026-10-120
OAAI
Kyle J. Kinney; Kun Jia; He Zhang; Ellen Schmaljohn; Thomas Osborne; Bernice Thommandru; Karthik Murugan; Andrea Sánchez-Peña; Sean West; Shengyao Chen; Roshani Codipilly; Morgan Sturgeon; Rolf Turk; Matthew S. McNeill; Mark Behlke; Ashley Jacobi; M. Kyle Cromer; Garrett Rettig; Gavin L. Kurgan
Single-cell and in vivo profiling reveal heterogeneous and organ-specific CRISPR-Cas9 off-target and translocation outcomes

单细胞和活体分析揭示CRISPR-Cas9脱靶和转位结果的异质性与器官特异性

Nature Communications
IF15.7
2026-08-260
OAAI
Alexandra Madsen; Niklas Selfjord; Marta Martinez-Lage; Anna-Lena Loyd; Gavin Kurgan; Mikaela Ståhlberg; Julia Lindgren; Julia Liz Touza; Leif Wigge; Mike Firth; Karl Nordström; Joseph Collin; Daniel Jachimowicz; Bastian Schiffthaler; Inken Dillmann; Panagiotis Antoniou; Aikaterini Emmanouilidi; Jonna Hellsten; Johan Forsström; Kerstin Magnell; Ashley Jacobi; Mark Behlke; Michelle Porritt; Katja Madeyski-Bengtson; Marcello Maresca; Pinar Akcakaya
UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems

UNCOVERseq 实现了跨CRISPR-Cas模态和系统的敏感且可控的基因编辑脱靶位点鉴定

Nature Communications
IF15.7
2026-08-110
OA
Kyle J. Kinney; Kun Jia; He Zhang; Ellen Schmaljohn; Thomas Osborne; Bernice Thommandru; Karthik Murugan; Andrea Sánchez-Peña; Sean West; Shengyao Chen; Roshani Codipilly; Morgan Sturgeon; Rolf Turk; Matthew S. McNeill; Mark Behlke; Ashley Jacobi; M. Kyle Cromer; Garrett Rettig; Gavin L. Kurgan
Clinical development of tacrolimus-resistant regulatory T cells to enable simultaneous immunosuppression and immune regulation

他克莫司抵抗性调节性T细胞的临床开发以实现同时免疫抑制和免疫调节

MOLECULAR THERAPY ADVANCES
IF0
2026-05-012
OAAI
Zarrinrad, Ghazaleh; Burkhardt, Lisa-Marie; Beltran-Mestres, Claudia; Romero-Suarez, Silvina; Wagner, Dimitrios Laurin; Schlickeiser, Stephan; Stein, Maik; Wendering, Desiree Jacqueline; de la Cebosa, Ivan Juky Carrera Diaz; Ehlen, Lukas; Hamm, Frederik; Kurgan, Gavin L.; Durek, Pawel; Heinrich, Frederik; Giri, Anamika; Pu, Yaolin; Ou, Kristy; Hoffmann, Henrike; Muench, Sandra; Stuewe, Insa; Dolling, Sven; McCallion, Oliver; Kaeda, Jaspal; Kath, Jonas; Schulenberg, Sarah; Wiese, Niklas; Nazari, Abdolreza; Peter, Lena; Picht, Samira; Sanchez-Pena, Andrea; Usman, Olalekan; Brommel, Christian; Turk, Rolf; Rettig, Garrett; Sturgeon, Morgan; Osborne, Thomas L.; Jacobi, Ashley; Friedrich, Rebecca; Kaufmann, Masako Monika; Klermund, Julia; Fink, Simon; Templin, Markus F.; Roemhild, Andy; Kaiser, Daniel; Klein, Oliver; Cathomen, Toni; Mashreghi, Mir-Farzin; Issa, Fadi; Polansky, Julia K.; Volk, Hans-Dieter; Schmueck-Henneresse, Michael; Reinke, Petra; Amini, Leila
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
NATURE MEDICINE
IF50
2018-08-06595
OAAI
Vakulskas, Christopher A.; Dever, Daniel P.; Rettig, Garrett R.; Turk, Rolf; Jacobi, Ashley M.; Collingwood, Michael A.; Bode, Nicole M.; McNeill, Matthew S.; Yan, Shuqi; Camarena, Joab; Lee, Ciaran M.; Parka, So Hyun; Wiebking, Volker; Bak, Rasmus O.; Gomez-Ospina, Natalia; Pavel-Dinu, Mara; Sun, Wenchao; Bao, Gang; Porteus, Matthew H.; Behlke, Mark A.
An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein
ELIFE
IF0
2018-04-1141
OAAI
Dewari, Pooran Singh; Southgate, Benjamin; Mccarten, Katrina; Monogarov, German; O'Duibhir, Eoghan; Quinn, Niall; Tyrer, Ashley; Leitner, Marie-Christin; Plumb, Colin; Kalantzaki, Maria; Blin, Carla; Finch, Rebecca; Bressan, Raul Bardini; Morrison, Gillian; Jacobi, Ashley M.; Behlke, Mark A.; von Kriegsheim, Alex; Tomlinson, Simon; Krijgsveld, Jeroen; Pollard, Steven M.
Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins

Easa-crispr: 一种使用长ssDNA供体和CRISPR核糖核蛋白一步生成携带条件和插入等位基因的小鼠的稳健方法

GENOME BIOLOGY
IF9.4
2017-05-17363
OAAI
Quadros, Rolen M.; Miura, Hiromi; Harms, Donald W.; Akatsuka, Hisako; Sato, Takehito; Aida, Tomomi; Redder, Ronald; Richardson, Guy P.; Inagaki, Yutaka; Sakai, Daisuke; Buckley, Shannon M.; Seshacharyulu, Parthasarathy; Batra, Surinder K.; Behlke, Mark A.; Zeiner, Sarah A.; Jacobi, Ashley M.; Izu, Yayoi; Thoreson, Wallace B.; Urness, Lisa D.; Mansour, Suzanne L.; Ohtsuka, Masato; Gurumurthy, Channabasavaiah B.
Correlating In Vitro Splice Switching Activity With Systemic In Vivo Delivery Using Novel ZEN-modified Oligonucleotides

使用新型ZEN修饰的寡核苷酸将体外剪接转换活性与全身体内递送相关联

MOLECULAR THERAPY-NUCLEIC ACIDS
IF0
2014-01-0110
OAAI
Hammond, Suzan M.; McClorey, Graham; Nordin, Joel Z.; Godfrey, Caroline; Stenler, Sofia; Lennox, Kim A.; Smith, C. I. Edvard; Jacobi, Ashley M.; Varela, Miguel A.; Lee, Yi; Behlke, Mark A.; Wood, Matthew J. A.; Andaloussi, Samir E. L.
Post-Transcriptional Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Expression and Function by MicroRNAs

Microrna对囊性纤维化跨膜传导调节因子表达和功能的转录后调控

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
IF5.3
2013-10-0187
OAAI
Ramachandran, Shyam; Karp, Philip H.; Osterhaus, Samantha R.; Jiang, Peng; Wohlford-Lenane, Christine; Lennox, Kim A.; Jacobi, Ashley M.; Praekh, Kal; Rose, Scott D.; Behlke, Mark A.; Xing, Yi; Welsh, Michael J.; McCray, Paul B., Jr.

研究方向

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M
Mark A. Behlke
H 指数:63论文数:196被引数:1.6万
G
Garrett R. Rettig
H 指数:20论文数:44被引数:2,533
R
Rolf Turk
H 指数:23论文数:48被引数:2,575
G
Gavin Kurgan
H 指数:15论文数:38被引数:1,352
P
Paul B. McCray
H 指数:95论文数:368被引数:3.3万
S
Shyam Ramachandran
H 指数:19论文数:62被引数:3,028
S
Scott D. Rose
H 指数:24论文数:68被引数:3,193
K
Kim A. Lennox
H 指数:19论文数:45被引数:2,577
M
Morgan Sturgeon
H 指数:7论文数:17被引数:427
M
Matthew McNeill
H 指数:18论文数:52被引数:3,200