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G

Gavin Kurgan

integrated dna technologies
H指数:15
被引数:1,352

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Author Correction: UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems

作者更正：UNCOVERseq实现了对CRISPR-Cas模态和系统中敏感且可控的基因编辑脱靶位点的鉴定

Nature Communications
IF15.7
2026-10-120
OAAI
Kyle J. Kinney; Kun Jia; He Zhang; Ellen Schmaljohn; Thomas Osborne; Bernice Thommandru; Karthik Murugan; Andrea Sánchez-Peña; Sean West; Shengyao Chen; Roshani Codipilly; Morgan Sturgeon; Rolf Turk; Matthew S. McNeill; Mark Behlke; Ashley Jacobi; M. Kyle Cromer; Garrett Rettig; Gavin L. Kurgan
Single-cell and in vivo profiling reveal heterogeneous and organ-specific CRISPR-Cas9 off-target and translocation outcomes

单细胞和活体分析揭示CRISPR-Cas9脱靶和转位结果的异质性与器官特异性

Nature Communications
IF15.7
2026-08-260
OAAI
Alexandra Madsen; Niklas Selfjord; Marta Martinez-Lage; Anna-Lena Loyd; Gavin Kurgan; Mikaela Ståhlberg; Julia Lindgren; Julia Liz Touza; Leif Wigge; Mike Firth; Karl Nordström; Joseph Collin; Daniel Jachimowicz; Bastian Schiffthaler; Inken Dillmann; Panagiotis Antoniou; Aikaterini Emmanouilidi; Jonna Hellsten; Johan Forsström; Kerstin Magnell; Ashley Jacobi; Mark Behlke; Michelle Porritt; Katja Madeyski-Bengtson; Marcello Maresca; Pinar Akcakaya
UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems

UNCOVERseq 实现了跨CRISPR-Cas模态和系统的敏感且可控的基因编辑脱靶位点鉴定

Nature Communications
IF15.7
2026-08-110
OA
Kyle J. Kinney; Kun Jia; He Zhang; Ellen Schmaljohn; Thomas Osborne; Bernice Thommandru; Karthik Murugan; Andrea Sánchez-Peña; Sean West; Shengyao Chen; Roshani Codipilly; Morgan Sturgeon; Rolf Turk; Matthew S. McNeill; Mark Behlke; Ashley Jacobi; M. Kyle Cromer; Garrett Rettig; Gavin L. Kurgan
Clinical development of tacrolimus-resistant regulatory T cells to enable simultaneous immunosuppression and immune regulation

他克莫司抵抗性调节性T细胞的临床开发以实现同时免疫抑制和免疫调节

MOLECULAR THERAPY ADVANCES
IF0
2026-05-012
OAAI
Zarrinrad, Ghazaleh; Burkhardt, Lisa-Marie; Beltran-Mestres, Claudia; Romero-Suarez, Silvina; Wagner, Dimitrios Laurin; Schlickeiser, Stephan; Stein, Maik; Wendering, Desiree Jacqueline; de la Cebosa, Ivan Juky Carrera Diaz; Ehlen, Lukas; Hamm, Frederik; Kurgan, Gavin L.; Durek, Pawel; Heinrich, Frederik; Giri, Anamika; Pu, Yaolin; Ou, Kristy; Hoffmann, Henrike; Muench, Sandra; Stuewe, Insa; Dolling, Sven; McCallion, Oliver; Kaeda, Jaspal; Kath, Jonas; Schulenberg, Sarah; Wiese, Niklas; Nazari, Abdolreza; Peter, Lena; Picht, Samira; Sanchez-Pena, Andrea; Usman, Olalekan; Brommel, Christian; Turk, Rolf; Rettig, Garrett; Sturgeon, Morgan; Osborne, Thomas L.; Jacobi, Ashley; Friedrich, Rebecca; Kaufmann, Masako Monika; Klermund, Julia; Fink, Simon; Templin, Markus F.; Roemhild, Andy; Kaiser, Daniel; Klein, Oliver; Cathomen, Toni; Mashreghi, Mir-Farzin; Issa, Fadi; Polansky, Julia K.; Volk, Hans-Dieter; Schmueck-Henneresse, Michael; Reinke, Petra; Amini, Leila
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency

基因校正的RAG2-SCID人造血干细胞恢复V(D)J-重组酶和拯救淋巴缺陷

BLOOD ADVANCES
IF7.1
2024-04-091
OAAI
Pavel-Dinu, Mara; Gardner, Cameron L.; Nakauchi, Yusuke; Kawai, Tomoki; Delmonte, Ottavia M.; Palterer, Boaz; Bosticardo, Marita; Pala, Francesca; Viel, Sebastien; Malech, Harry L.; Ghanim, Hana Y.; Bode, Nicole M.; Kurgan, Gavin L.; Detweiler, Angela M.; Vakulskas, Christopher A.; Neff, Norma F.; Sheikali, Adam; Menezes, Sherah T.; Chrobok, Jade; Gonzalez, Elaine M. Hernandez; Majeti, Ravindra; Notarangelo, Luigi D.; Porteus, Matthew H.
Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo
NATURE COMMUNICATIONS
IF15.7
2023-12-0511
OAAI
Kulhankova, Katarina; Traore, Soumba; Cheng, Xue; Benk-Fortin, Hadrien; Hallee, Stephanie; Harvey, Mario; Roberge, Joannie; Couture, Frederic; Kohli, Sajeev; Gross, Thomas J.; Meyerholz, David K.; Rettig, Garrett R.; Thommandru, Bernice; Kurgan, Gavin; Wohlford-Lenane, Christine; Hartigan-O'Connor, Dennis J.; Yates, Bradley P.; Newby, Gregory A.; Liu, David R.; Tarantal, Alice F.; Guay, David; McCray, Paul B., Jr.
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines (vol 12, 3908, 2021)
NATURE COMMUNICATIONS
IF15.7
2021-07-193
OAAI
Zhang, Liyang; Zuris, John A.; Viswanathan, Ramya; Edelstein, Jasmine N.; Turk, Rolf; Thommandru, Bernice; Rube, H. Tomas; Glenn, Steve E.; Collingwood, Michael A.; Bode, Nicole M.; Beaudoin, Sarah F.; Lele, Swarali; Scott, Sean N.; Wasko, Kevin M.; Sexton, Steven; Borges, Christopher M.; Schubert, Mollie S.; Kurgan, Gavin L.; McNeill, Matthew S.; Fernandez, Cecilia A.; Myer, Vic E.; Morgan, Richard A.; Behlke, Mark A.; Vakulskas, Christopher A.
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

AsCas12a超核酸酶促进治疗细胞药物的快速生成

NATURE COMMUNICATIONS
IF15.7
2021-06-2377
OAAI
Zhang, Liyang; Zuris, John A.; Viswanathan, Ramya; Edelstein, Jasmine N.; Turk, Rolf; Thommandru, Bernice; Rube, H. Tomas; Glenn, Steve E.; Collingwood, Michael A.; Bode, Nicole M.; Beaudoin, Sarah F.; Lele, Swarali; Scott, Sean N.; Wasko, Kevin M.; Sexton, Steven; Borges, Christopher M.; Schubert, Mollie S.; Kurgan, Gavin L.; McNeill, Matthew S.; Fernandez, Cecilia A.; Myer, Vic E.; Morgan, Richard A.; Behlke, Mark A.; Vakulskas, Christopher A.
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
NATURE MEDICINE
IF50
2021-03-1853
OAAI
Cromer, M. Kyle; Camarena, Joab; Martin, Renata M.; Lesch, Benjamin J.; Vakulskas, Christopher A.; Bode, Nicole M.; Kurgan, Gavin; Collingwood, Michael A.; Rettig, Garrett R.; Behlke, Mark A.; Lemgart, Viktor T.; Zhang, Yankai; Goyal, Ankush; Zhao, Feifei; Ponce, Ezequiel; Srifa, Waracharee; Bak, Rasmus O.; Uchida, Naoya; Majeti, Ravindra; Sheehan, Vivien A.; Tisdale, John F.; Dever, Daniel P.; Porteus, Matthew H.
Large-scale GMP-compliant CRISPR-Cas9-mediated deletion of the glucocorticoid receptor in multivirus-specific T cells
BLOOD ADVANCES
IF7.1
2020-07-2724
OAAI
Basar, Rafet; Daher, May; Uprety, Nadima; Gokdemir, Elif; Alsuliman, Abdullah; Ensley, Emily; Ozcan, Gonca; Mendt, Mayela; Sanabria, Mayra Hernandez; Kerbauy, Lucila Nassif; Cortes, Ana Karen Nunez; Li, Li; Banerjee, Pinaki P.; Muniz-Feliciano, Luis; Acharya, Sunil; Fowlkes, Natalie W.; Lu, Junjun; Li, Sufang; Mielke, Stephan; Kaplan, Mecit; Nandivada, Vandana; Bdaiwi, Mustafa; Kontoyiannis, Alexander D.; Li, Ye; Liu, Enli; Ang, Sonny; Marin, David; Brunetti, Lorenzo; Gundry, Michael C.; Turk, Rolf; Schubert, Mollie S.; Rettig, Garrett R.; McNeill, Matthew S.; Kurgan, Gavin; Behlke, Mark A.; Champlin, Richard; Shpall, Elizabeth J.; Rezvani, Katayoun

研究方向

暂未获取到该数据
G
Garrett R. Rettig
H 指数:20论文数:44被引数:2,533
M
Mark A. Behlke
H 指数:63论文数:196被引数:1.6万
R
Rolf Turk
H 指数:23论文数:48被引数:2,575
M
Matthew McNeill
H 指数:18论文数:52被引数:3,200
C
Christopher A. Vakulskas
H 指数:33论文数:52被引数:5,534
X
Xuan Wang
H 指数:34论文数:134被引数:8,433
N
Nicole M. Bode
H 指数:11论文数:17被引数:2,440
B
Bernice Thommandru
H 指数:7论文数:24被引数:496
A
Ashley M. Jacobi
H 指数:21论文数:49被引数:3,532
M
M. Kyle Cromer
H 指数:15论文数:45被引数:2,346