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M

Michelle R. Jones

cedars-sinai medical center
H指数:28
被引数:3,645

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Genomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome

基因组分析暗示多囊卵巢综合征中的激素和代谢失调

Nature Genetics
IF29
2026-04-230
OAAI
Loes M. E. Moolhuijsen; Jia Zhu; Benjamin H. Mullin; Natàlia Pujol-Gualdo; Ky’Era V. Actkins; Jasmine A. Mack; Hridya Rao; Bhavi Trivedi; Katherine A. Kentistou; Yajie Zhao; David Westergaard; Jaakko S. Tyrmi; Gudmar Thorleifsson; Yanfei Zhang; Laura Wittemans; Amber DeVries; Kelly Brewer; Ryan Sisk; Rebecca Danning; Michael H. Preuss; Michelle R. Jones; Katherine S. Ruth; Marianne Andersen; Ricardo Azziz; Karina Banasik; Michael Boehnke; Linda Broer; Søren Brunak; Yee-Ming Chan; Daniel I. Chasman; Mark Daly; David A. Ehrmann; Bart C. Fauser; Lars G. Fritsche; M. Geoffrey Hayes; Chunyan He; Hongyan Huang; Irina Kowalska; Peter Kraft; Richard S. Legro; Nan Lin; Ruth J. Loos; Yvonne V. Louwers; Reedik Magi; Mark I. McCarthy; Laure Morin-Papunen; Jean V. Morrison; Cynthia Morton; Girish N. Nadkarni; Benjamin M. Neale; Henriette Svarre Nielsen; Mette Nyegaard; Sisse R. Ostrowski; Ole B. V. Pedersen; Erik Sørensen; Christina Mikkelsen; Christian Erikstrup; Kathrine A. Kaspersen; Mie T. Bruun; Bitten Aagaard; Henrik Ullum; Barbara Obermayer-Pietsch; Aarno Palotie; Mary P. Reeve; Andres Salumets; Richa Saxena; Timothy D. Spector; Bronwyn G. A. Stuckey; Unnur Thorsteinsdottir; André G. Uitterlinden; Margrit Urbanek; Sebastian Zöllner; David A. van Heel; Joel N. Hirschhorn; Kari Stefansson; John R. B. Perry; Unnur Styrkarsdottir; Scott G. Wilson; Terhi Piltonen; Triin Laisk; Marjo-Riitta Jarvelin; Kharis Burns; Anne E. Justice; Hannele Laivuori; Ken K. Ong; Mark O. Goodarzi; Lea K. Davis; Andrea Dunaif; Cecilia M. Lindgren; Joop S. E. Laven; Stephen Franks; Jenny A. Visser; Corrine K. Welt; Tugce Karaderi; Felix R. Day
Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer

398,238名女性的全基因组关联研究揭示了七个与高级别浆液性卵巢癌相关的位点

npj Genomic Medicine
IF4.8
2025-11-200
OAAI
Daniel R. Barnes; Jonathan P. Tyrer; Joe Dennis; Goska Leslie; Manjeet K. Bolla; Michael Lush; Amber M. Aeilts; Kristiina Aittomäki; Nadine Andrieu; Irene L. Andrulis; Hoda Anton-Culver; Adalgeir Arason; Banu K. Arun; Judith Balmaña; Elisa V. Bandera; Rosa B. Barkardottir; Lieke P. V. Berger; Amy Berrington de Gonzalez; Pascaline Berthet; Katarzyna Białkowska; Line Bjørge; Amie M. Blanco; Marinus J. Blok; Kristie A. Bobolis; Natalia V. Bogdanova; James D. Brenton; Henriett Butz; Saundra S. Buys; Maria A. Caligo; Ian Campbell; Carmen Castillo; Kathleen B. M. Claes; Sarah V. Colonna; Linda S. Cook; Mary B. Daly; Agnieszka Dansonka-Mieszkowska; Miguel de la Hoya; Anna deFazio; Allison DePersia; Yuan Chun Ding; Jennifer A. Doherty; Susan M. Domchek; Thilo Dörk; Zakaria Einbeigi; Christoph Engel; D. Gareth Evans; Lenka Foretova; Renée T. Fortner; Florentia Fostira; Maria Cristina Foti; Eitan Friedman; Megan N. Frone; Patricia A. Ganz; Aleksandra Gentry-Maharaj; Gord Glendon; Andrew K. Godwin; Anna González-Neira; Mark H. Greene; Jacek Gronwald; Aliana Guerrieri-Gonzaga; Ute Hamann; Thomas V. O. Hansen; Holly R. Harris; Jan Hauke; Florian Heitz; Frans B. L. Hogervorst; Maartje J. Hooning; John L. Hopper; Chad D. Huff; David G. Huntsman; Evgeny N. Imyanitov; Louise Izatt; Anna Jakubowska; Paul A. James; Ramunas Janavicius; Esther M. John; Siddhartha Kar; Beth Y. Karlan; Catherine J. Kennedy; Lambertus A.L.M. Kiemeney; Irene Konstantopoulou; Jolanta Kupryjanczyk; Yael Laitman; Ofer Lavie; Kate Lawrenson; Jenny Lester; Fabienne Lesueur; Carlos Lopez-Pleguezuelos; Phuong L. Mai; Siranoush Manoukian; Taymaa May; Iain A. McNeish; Usha Menon; Roger L. Milne; Francesmary Modugno; Jennifer M. Mongiovi; Marco Montagna; Kirsten B. Moysich; Susan L. Neuhausen; Finn C. Nielsen; Catherine Noguès; Edit Oláh; Olufunmilayo I. Olopade; Ana Osorio; Laura Papi; Harsh Pathak; Celeste L. Pearce; Inge S. Pedersen; Ana Peixoto; Tanja Pejovic; Pei-Chen Peng; Beth N. Peshkin; Paolo Peterlongo; C. Bethan Powell; Darya Prokofyeva; Miquel Angel Pujana; Paolo Radice; Muhammad U. Rashid; Gad Rennert; George Richenberg; Dale P. Sandler; Naoko Sasamoto; Veronica W. Setiawan; Priyanka Sharma; Weiva Sieh; Christian F. Singer; Katie Snape; Anna P. Sokolenko; Penny Soucy; Melissa C. Southey; Dominique Stoppa-Lyonnet; Rebecca Sutphen; Christian Sutter; Yen Y. Tan; Manuel R. Teixeira; Kathryn L. Terry; Liv Cecilie V. Thomsen; Marc Tischkowitz; Amanda E. Toland; Toon Van Gorp; Ana Vega; Digna R. Velez Edwards; Penelope M. Webb; Jeffrey N. Weitzel; Nicolas Wentzensen; Alice S. Whittemore; Stacey J. Winham; Anna H. Wu; Siddhartha Yadav; Yao Yu; Argyrios Ziogas; Andrew Berchuck; Fergus J. Couch; Ellen L. Goode; Marc T. Goodman; Alvaro N. Monteiro; Kenneth Offit; Susan J. Ramus; Harvey A. Risch; Joellen M. Schildkraut; Mads Thomassen; Jacques Simard; Douglas F. Easton; Michelle R. Jones; Georgia Chenevix-Trench; Simon A. Gayther; Antonis C. Antoniou; Paul D. P. Pharoah
Exome sequencing identifies HELB as a novel susceptibility gene for non-mucinous, non-high-grade-serous epithelial ovarian cancer
EUROPEAN JOURNAL OF HUMAN GENETICS
IF4.6
2025-02-120
OAAI
Dicks, Ed M.; Tyrer, Jonthan P.; Ezquina, Suzana; Jones, Michelle; Baierl, John; Peng, Pei-Chen; Diaz, Michael; Goode, Ellen; Winham, Stacey J.; Doerk, Thilo; Gorp, Toon Van; Fazio, Anna; Bowtell, David D. L.; Garsed, Dale W.; Odunsi, Kunle; Moysich, Kirsten; Pavanello, Marina; Fostira, Florentia; Webb, Penelope M.; Soukupova, Jana; Cohen, Paul A.; Sieh, Weiva; Fortner, Renee Turzanski; Ricker, Charite; Karlan, Beth; Campbell, Ian; Brenton, James D.; Ramus, Susan J.; Gayther, Simon A.; Pharoah, Paul D. P.
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions

整合多组学分析以确定卵巢癌风险区域的遗传和功能机制

AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2024-06-016
PRE
Dareng, Eileen O.; Coetzee, Simon G.; Tyrer, Jonathan P.; Peng, Pei-Chen; Rosenow, Will; Chen, Stephanie; Davis, Brian D.; Dezem, Felipe Segato; Seo, Ji-Heui; Nameki, Robbin; Reyes, Alberto L.; Aben, Katja K. H.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Aravantinos, Gerasimos; Bandera, Elisa V.; Freeman, Laura E. Beane; Beckmann, Matthias W.; Beeghly-Fadiel, Alicia; Benitez, Javier; Bernardini, Marcus Q.; Bjorge, Line; Black, Amanda; Bogdanova, Natalia V.; Bolton, Kelly L.; Brenton, James D.; Budzilowska, Agnieszka; Butzow, Ralf; Cai, Hui; Campbell, Ian; Cannioto, Rikki; Chang-Claude, Jenny; Chanock, Stephen J.; Chen, Kexin; Chenevix-Trench, Georgia; Chiew, Yoke-Eng; Cook, Linda S.; DeFazio, Anna; Dennis, Joe; Doherty, Jennifer A.; Doerk, Thilo; du Bois, Andreas; Duerst, Matthias; Eccles, Diana M.; Ene, Gabrielle; Fasching, Peter A.; Flanagan, James M.; Fortner, Renee T.; Fostira, Florentia; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Goodman, Marc T.; Gronwald, Jacek; Haiman, Christopher A.; Hakansson, Niclas; Heitz, Florian; Hildebrandt, Michelle A. T.; Hogdall, Estrid; Hogdall, Claus K.; Huang, Ruea-Yea; Jensen, Allan; Jones, Michael E.; Kang, Daehee; Karlan, Beth Y.; Karnezis, Anthony N.; Kelemen, Linda E.; Kennedy, Catherine J.; Khusnutdinova, Elza K.; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Kupryjanczyk, Jolanta; Labrie, Marilyne; Lambrechts, Diether; Larson, Melissa C.; Le, Nhu D.; Lester, Jenny; Li, Lian; Lubinski, Jan; Lush, Michael; Marks, Jeffrey R.; Matsuo, Keitaro; May, Taymaa; McLaughlin, John R.; McNeish, Iain A.; Menon, Usha; Missmer, Stacey; Modugno, Francesmary; Moffitt, Melissa; Monteiro, Alvaro N.; Moysich, Kirsten B.; Narod, Steven A.; Nguyen-Dumont, Tu; Odunsi, Kunle; Olsson, Hakan; Onland-Moret, N. Charlotte; Park, Sue K.; Pejovic, Tanja; Permuth, Jennifer B.; Piskorz, Anna; Prokofyeva, Darya; Riggan, Marjorie J.; Risch, Harvey A.; Rodriguez-Antona, Cristina; Rossing, Mary Anne; Sandler, Dale P.; Setiawan, V. Wendy; Shan, Kang; Song, Honglin; Southey, Melissa C.; Steed, Helen; Sutphen, Rebecca; Swerdlow, Anthony J.; Teo, Soo Hwang; Terry, Kathryn L.; Thompson, Pamela J.; Thomsen, Liv Cecilie Vestrheim; Titus, Linda; Trabert, Britton; Travis, Ruth; Tworoger, Shelley S.; Valen, Ellen; Van Nieuwenhuysen, Els; Edwards, Digna Velez; Vierkant, Robert A.; Webb, Penelope M.; Weinberg, Clarice R.; Weise, Rayna Matsuno; Wentzensen, Nicolas; White, Emily; Winham, Stacey J.; Wolk, Alicja; Woo, Yin-Ling; Wu, Anna H.; Yan, Li; Yannoukakos, Drakoulis; Zeinomar, Nur; Zheng, Wei; Ziogas, Argyrios; Berchuck, Andrew; Goode, Ellen L.; Huntsman, David G.; Pearce, Celeste L.; Ramus, Susan J.; Sellers, Thomas A.; Freedman, Matthew L.; Lawrenson, Kate; Schildkraut, Joellen M.; Hazelett, Dennis; Plummer, Jasmine T.; Kar, Siddhartha; Jones, Michelle R.; Pharoah, Paul D. P.; Gayther, Simon A.
Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci

拷贝数变异是已知和新的风险位点的卵巢癌风险等位基因

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
2022-10-106
OAAI
DeVries, Amber A.; Dennis, Joe; Tyrer, Jonathan P.; Peng, Pei-Chen; Coetzee, Simon G.; Reyes, Alberto L.; Plummer, Jasmine T.; Davis, Brian D.; Chen, Stephanie S.; Dezem, Felipe Segato; Aben, Katja K. H.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Beckmann, Matthias W.; Beeghly-Fadiel, Alicia; Berchuck, Andrew; Bogdanova, Natalia, V; Bogdanova-Markov, Nadja; Brenton, James D.; Butzow, Ralf; Campbell, Ian; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Cook, Linda S.; DeFazio, Anna; Doherty, Jennifer A.; Dork, Thilo; Eccles, Diana M.; Eliassen, A. Heather; Fasching, Peter A.; Fortner, Renee T.; Giles, Graham G.; Goode, Ellen L.; Goodman, Marc T.; Gronwald, Jacek; Hakansson, Niclas; Hildebrandt, Michelle A. T.; Huff, Chad; Huntsman, David G.; Jensen, Allan; Kar, Siddhartha; Karlan, Beth Y.; Khusnutdinova, Elza K.; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Kupryjanczyk, Jolanta; Labrie, Marilyne; Lambrechts, Diether; Le, Nhu D.; Lubinski, Jan; May, Taymaa; Menon, Usha; Milne, Roger L.; Modugno, Francesmary; Monteiro, Alvaro N.; Moysich, Kirsten B.; Odunsi, Kunle; Olsson, Hakan; Pearce, Celeste L.; Pejovic, Tanja; Ramus, Susan J.; Riboli, Elio; Riggan, Marjorie J.; Romieu, Isabelle; Sandler, Dale P.; Schildkraut, Joellen M.; Setiawan, V. Wendy; Sieh, Weiva; Song, Honglin; Sutphen, Rebecca; Terry, Kathryn L.; Thompson, Pamela J.; Titus, Linda; Tworoger, Shelley S.; Van Nieuwenhuysen, Els; Edwards, Digna Velez; Webb, Penelope M.; Wentzensen, Nicolas; Whittemore, Alice S.; Wolk, Alicja; Wu, Anna H.; Ziogas, Argyrios; Freedman, Matthew L.; Lawrenson, Kate; Pharoah, Paul D. P.; Easton, Douglas F.; Gayther, Simon A.; Jones, Michelle R.
DNA methylation and transcriptomic features are preserved throughout disease recurrence and chemoresistance in high grade serous ovarian cancers

在高级别浆液性卵巢癌中，DNA甲基化和转录组学特征在疾病复发和化疗耐药过程中得以保留

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2022-07-2710
OAAI
Gull, Nicole; Jones, Michelle R.; Peng, Pei-Chen; Coetzee, Simon G.; Silva, Tiago C.; Plummer, Jasmine T.; Reyes, Alberto Luiz P.; Davis, Brian D.; Chen, Stephanie S.; Lawrenson, Kate; Lester, Jenny; Walsh, Christine; Rimel, Bobbie J.; Li, Andrew J.; Cass, Ilana; Berg, Yonatan; Govindavari, John-Paul B.; Rutgers, Joanna K. L.; Berman, Benjamin P.; Karlan, Beth Y.; Gayther, Simon A.
Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals

5 p15.33区域的大规模交叉癌症精细映射揭示了多个独立信号

HUMAN GENETICS AND GENOMICS ADVANCES
IF3.6
2021-07-0114
OAAI
Chen, Hongjie; Majumdar, Arunabha; Wang, Lu; Kar, Siddhartha; Brown, Kevin M.; Feng, Helian; Turman, Constance; Dennis, Joe; Easton, Douglas; Michailidou, Kyriaki; Simard, Jacques; Bishop, Timothy; Cheng, Iona C.; Huyghe, Jeroen R.; Schmit, Stephanie L.; O'Mara, Tracy A.; Spurdle, Amanda B.; Gharahkhani, Puya; Schumacher, Johannes; Jankowski, Janusz; Gockel, Ines; Bondy, Melissa L.; Houlston, Richard S.; Jenkins, Robert B.; Melin, Beatrice; Lesseur, Corina; Ness, Andy R.; Diergaarde, Brenda; Olshan, Andrew F.; Amos, Christopher, I; Christiani, David C.; Landi, Maria T.; McKay, James D.; Brossard, Myriam; Iles, Mark M.; Law, Matthew H.; MacGregor, Stuart; Beesley, Jonathan; Jones, Michelle R.; Tyrer, Jonathan; Winham, Stacey J.; Klein, Alison P.; Petersen, Gloria; Li, Donghui; Wolpin, Brian M.; Eeles, Rosalind A.; Haiman, Christopher A.; Kote-Jarai, Zsofia; Schumacher, Fredrick R.; Brennan, Paul; Chanock, Stephen J.; Gaborieau, Valerie; Purdue, Mark P.; Pharoah, Paul; Hung, Rayjean J.; Amundadottir, Laufey T.; Kraft, Peter; Pasaniuc, Bogdan; Lindstrom, Sara
Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites
AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2020-10-0118
OAAI
Jones, Michelle R.; Peng, Pei-Chen; Coetzee, Simon G.; Tyrer, Jonathan; Reyes, Alberto Luiz P.; Corona, Rosario, I; Davis, Brian; Chen, Stephanie; Dezem, Felipe; Seo, Ji-Heui; Kar, Siddartha; Dareng, Eileen; Berman, Benjamin P.; Freedman, Matthew L.; Plummer, Jasmine T.; Lawrenson, Kate; Pharoah, Paul; Hazelett, Dennis J.; Gayther, Simon A.
A Polygenic and Phenotypic Risk Prediction for Polycystic Ovary Syndrome Evaluated by Phenome-Wide Association Studies

通过全表型关联研究评估的多囊卵巢综合征的多基因和表型风险预测

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
IF5.1
2020-01-0939
OAAI
Joo, Yoonjung Yoonie; Actkins, Ky'Era; Pacheco, Jennifer A.; Basile, Anna O.; Carroll, Robert; Crosslin, David R.; Day, Felix; Denny, Joshua C.; Edwards, Digna R. Velez; Hakonarson, Hakon; Harley, John B.; Hebbring, Scott J.; Ho, Kevin; Jarvik, Gail P.; Jones, Michelle; Karaderi, Tugce; Mentch, Frank D.; Meun, Cindy; Namjou, Bahram; Pendergrass, Sarah; Ritchie, Marylyn D.; Stanaway, Ian B.; Urbanek, Margrit; Walunas, Theresa L.; Smith, Maureen; Chisholm, Rex L.; Kho, Abel N.; Davis, Lea; Hayes, M. Geoffrey
Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria (vol 14, e1007813, 2018)

多囊卵巢综合征的大规模全基因组荟萃分析表明，不同诊断标准具有共同的遗传结构 (第14卷，e1007813，2018)

PLOS GENETICS
IF3.7
2019-12-0510
OAAI
Day, Felix; Karaderi, Tugce; Jones, Michelle R.; Meun, Cindy; He, Chunyan; Drong, Alex; Kraft, Peter; Lin, Nan; Huang, Hongyan; Broer, Linda; Magi, Reedik; Saxena, Richa; Laisk, Triin; Urbanek, Margrit; Hayes, M. Geoffrey; Thorleifsson, Gudmar; Fernandez-Tajes, Juan; Mahajan, Anubha; Mullin, Benjamin H.; Stuckey, Bronwyn G. A.; Spector, Timothy D.; Wilson, Scott G.; Goodarzi, Mark O.; Davis, Lea; Obermayer-Pietsch, Barbara; Uitterlinden, Andre G.; Anttila, Verneri; Neale, Benjamin M.; Jarvelin, Marjo-Riitta; Fauser, Bart; Kowalska, Irina; Visser, Jenny A.; Andersen, Marianne; Ong, Ken; Stener-Victorin, Elisabet; Ehrmann, David; Legro, Richard S.; Salumets, Andres; McCarthy, Mark I.; Morin-Papunen, Laure; Thorsteinsdottir, Unnur; Stefansson, Kari; Styrkarsdottir, Unnur; Perry, John R. B.; Dunaif, Andrea; Laven, Joop; Franks, Steve; Lindgren, Cecilia M.; Welt, Corrine K.
Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

多囊卵巢综合征的大规模全基因组荟萃分析表明，不同诊断标准具有共同的遗传结构

PLOS GENETICS
IF3.7
2018-12-19351
OAAI
Day, Felix; Karaderi, Tugce; Jones, Michelle R.; Meun, Cindy; He, Chunyan; Drong, Alex; Kraft, Peter; Lin, Nan; Huang, Hongyan; Broer, Linda; Magi, Reedik; Saxena, Richa; Laisk, Triin; Urbanek, Margrit; Hayes, M. Geoffrey; Thorleifsson, Gudmar; Fernandez-Tajes, Juan; Mahajan, Anubha; Mullin, Benjamin H.; Stuckey, Bronwyn G. A.; Spector, Timothy D.; Wilson, Scott G.; Goodarzi, Mark O.; Davis, Lea; Obermayer-Pietsch, Barbara; Uitterlinden, Andre G.; Anttila, Verneri; Neale, Benjamin M.; Jarvelin, Marjo-Riitta; Fauser, Bart; Kowalska, Irina; Visser, Jenny A.; Andersen, Marianne; Ong, Ken; Stener-Victorin, Elisabet; Ehrmann, David; Legro, Richard S.; Salumets, Andres; McCarthy, Mark I.; Morin-Papunen, Laure; Thorsteinsdottir, Unnur; Stefansson, Kari; Styrkarsdottir, Unnur; Perry, John R. B.; Dunaif, Andrea; Laven, Joop; Franks, Steve; Lindgren, Cecilia M.; Welt, Corrine K.

研究方向

暂未获取到该数据
M
Mark O. Goodarzi
H 指数:73论文数:383被引数:2.5万
R
Ricardo Azziz
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P
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Jerome I. Rotter
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S
Simon A. Gayther
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Jonathan P. Tyrer
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K
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P
Paul D.P. Pharoah
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R
Richard S. Legro
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K
Kent D. Taylor
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