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Ursodeoxycholic acid acts as an ileal FXR agonist in male mice with hepatic deficiency of FXR 熊去氧胆酸在FXR缺乏的雄性小鼠中充当回肠FXR激动剂。 Henry, Zakiyah R.; Maliha, Syeda; Basaly, Veronia; Yang, Zhenning; Taylor, Rulaiha E.; Otersen, Katherine; Meadows, Vik; Rizzolo, Daniel; Stofan, Mary; Bhattacharya, Anisha; Zhou, Peihong; Brinker, Anita; Yang, Ill; Zhang, Lanjing; Joseph, Laurie B.; Buckley, Brian; Kong, Bo; Guo, Grace L. 分享 收藏
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Effects of therapeutically approved individual bile acids on the development of metabolic dysfunction-associated steatohepatitis a low bile acid mouse model Taylor, Rulaiha; Basaly, Veronia; Kong, Bo; Yang, Ill; Brinker, Anita M.; Capece, Gina; Bhattacharya, Anisha; Henry, Zakiyah R.; Otersen, Katherine; Yang, Zhenning; Meadows, Vik; Mera, Stephanie; Joseph, Laurie B.; Zhou, Peihong; Aleksunes, Lauren M.; Roepke, Troy; Buckley, Brian; Guo, Grace L. 分享 收藏
Effects of intestine-specific deletion of FGF15 on the development of fatty liver disease with vertical sleeve gastrectomy Chow, Monica D.; Otersen, Katherine; Wassef, Andrew; Kong, Bo; Yamarthy, Sowmya; Rizzolo, Daniel; Yang, Ill; Buckley, Brian; Lu, Alexander; Crook, Naomi; Lee, Matthew; Gao, Judy; Naganand, Sareena; Stofan, Mary F.; Armstrong, Laura; Schumacher, Justin; Taylor, Rulaiha; Henry, Zakiyah; Basaly, Veronia; Yang, Zhenning; Zhang, Min; Huang, Mingxing; Kagan, Leonid; Brunetti, Luigi; Sadek, Ragui; Lee, Yi-Horng; Guo, Grace L. 分享 收藏
Identification and Functional Characterization of Alternative Transcripts of LncRNA HNF1A-AS1 and Their Impacts on Cell Growth, Differentiation, Liver Diseases, and in Response to Drug Induction Jin, Jing; Nguyen, Le Tra Giang; Wassef, Andrew; Sadek, Ragui; Schmitt, Timothy M.; Guo, Grace L.; Rasmussen, Theodore P.; Zhong, Xiao-bo 分享 收藏
First disclosure of AZD8421, a highly selective CDK2 inhibitor to address resistance to CDK4/6 inhibitors in breast and CCNE1-high cancers Denz, Christopher R.; Grondine, Michael; Fan, Jun; Hsu, Jessie Hao-Ru; Jackson, Anne; Robinson, James; Guo, Grace; Li, Wen; Wang, Yanjun; Martin, Maryann San; Prickett, Laura; Johannes, Jeffrey; Ghosh, Avipsa; Song, Kun; Sudhan, Dhivya; Vasalou, Christina; Richards, Ryan; Beaumont, Kevin; Peters, Matthew; Drew, Lisa; Fawell, Stephen; Goldberg, Frederick W. 分享 收藏
Characterization of individual bile acids in vivo utilizing a novel low bile acid mouse model Taylor, Rulaiha; Yang, Zhenning; Henry, Zakiyah; Capece, Gina; Meadows, Vik; Otersen, Katherine; Basaly, Veronia; Bhattacharya, Anisha; Mera, Stephanie; Zhou, Peihong; Joseph, Laurie; Yang, Ill; Brinker, Anita; Buckley, Brian; Kong, Bo; Guo, Grace L. 分享 收藏
Targeting the cell cycle with AZD8421, a potent and highly selective CDK2 inhibitor Denz, Christopher R.; Grondine, Michael; Fan, Jun; Hsu, Jessie Hao-Ru; Jackson, Anne; Robinson, James; Guo, Grace; Li, Wen; Wang, Yanjun; Martin, Maryann San; Prickett, Laura; Johannes, Jeffrey; Ghosh, Avipsa; Sudhan, Dhivya; Vasalou, Christina; Richards, Ryan; Beaumont, Kevin; Peters, Matt; Drew, Lisa; Fawell, Stephen; Goldberg, Frederick W. 分享 收藏
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Suppression of Lung Oxidative Stress, Inflammation, and Fibrosis following Nitrogen Mustard Exposure by the Selective Farnesoid X Receptor Agonist Obeticholic Acid Meshanni, Jaclynn A.; Lee, Jordan M.; Vayas, Kinal N.; Sun, Rachel; Jiang, Chenghui; Guo, Grace L.; Gow, Andrew J.; Laskin, Jeffrey D.; Laskin, Debra L. 分享 收藏
Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice Yang, Xue; Wang, Jianming; Chang, Chun-Yuan; Zhou, Fan; Liu, Juan; Xu, Huiting; Ibrahim, Maria; Gomez, Maria; Guo, Grace L.; Liu, Hao; Zong, Wei-Xing; Wondisford, Fredric E.; Su, Xiaoyang; White, Eileen; Feng, Zhaohui; Hu, Wenwei 分享 收藏
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BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors BID表达决定了AURKB或TTK抑制剂废除纺锤体组装检查点后癌细胞的凋亡命运 Bertran-Alamillo, Jordi; Gimenez-Capitan, Ana; Roman, Ruth; Talbot, Sara; Whiteley, Rebecca; Floc'h, Nicolas; Martinez-Perez, Elizabeth; Martin, Matthew J.; Smith, Paul D.; Sullivan, Ivana; Terp, Mikkel G.; Saeh, Jamal; Marino-Buslje, Cristina; Fabbri, Giulia; Guo, Grace; Xu, Man; Tornador, Cristian; Aguilar-Hernandez, Andres; Reguart, Noemi; Ditzel, Henrik J.; Martinez-Bueno, Alejandro; Nabau-Moreto, Nuria; Gasco, Amaya; Rosell, Rafael; Pease, J. Elizabeth; Polanska, Urszula M.; Travers, Jon; Urosevic, Jelena; Molina-Vila, Miguel A. 分享 收藏
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