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收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress
Fingerman, Dylan F.; O'Leary, David R.; Hansen, Ava R.; Tran, Thi; Harris, Brooke R.; Deweerd, Rachel A.; Hayer, Katharina E.; Fan, Jiayi; Chen, Emily; Tennakoon, Mithila; Meroni, Alice; Szeto, Julia H.; Devenport, Jessica; Lavigne, Danielle; Weitzman, Matthew D.; Shalem, Ophir; Bednarski, Jeffrey; Vindigni, Alessandro; Zhao, Xiaolan; Green, Abby M. 分享 收藏 Identifying mechanisms of acquired resistance to lorlatinib utilizing a genome-wide CRISPR-Cas9 screenKalna, Joshua Renn; Matkar, Smita; O'Drisoll, Emily; Balyasny, Skye; Calafatti, Matteo; Gerelus, Mark; Groff, Dave; Acholla, Tina; Casey, Colleen E.; Kamitsuka, Paul; Li, Grant; Pastor, Steven J.; Witek, Gabriela; Krytska, Kateryna; Lindsay, Jarrett; Shalem, Ophir; Mosse, Yael P. 分享 收藏 KOLF2.1J iPSCs carry CNVs associated with neurodevelopmental disordersGracia-Diaz, Carolina; Perdomo, Jonathan E.; Khan, Munir E.; Roule, Thomas; Disanza, Brianna L.; Cajka, Gregory G.; Lei, Sunyimeng; Gagne, Alyssa L.; Maguire, Jean Ann; Shalem, Ophir; Bhoj, Elizabeth J.; Ahrens-Nicklas, Rebecca C.; French, Deborah L.; Goldberg, Ethan M.; Wang, Kai; Glessner, Joseph T.; Akizu, Naiara 分享 收藏 Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neuronsSanthosh Kumar, Saranya; Naseri, Nima N.; Pather, Sarshan R.; Hallacli, Erinc; Ndayisaba, Alain; Buenaventura, Chris; Acosta, Karen; Roof, Jennifer; Fazelinia, Hossein; Spruce, Lynn A.; Luk, Kelvin; Khurana, Vikram; Rhoades, Elizabeth; Shalem, Ophir 分享 收藏 CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assemblySweeney, Katelyn M.; Chantarawong, Sapanna; Barbieri, Edward M.; Cajka, Greg; Liu, Matthew; Spruce, Lynn; Fazelinia, Hossein; Portz, Bede; Copley, Katie; Lapidot, Tomer; Duhamel, Lauren; Greenwald, Phoebe; Saida, Naseeb; Shalgi, Reut; Shorter, James; Shalem, Ophir 分享 收藏 A subpopulation of lipogenic brown adipocytes drives thermogenic memoryLundgren, Patrick; Sharma, Prateek V.; Dohnalova, Lenka; Coleman, Kyle; Uhr, Giulia T.; Kircher, Susanna; Litichevskiy, Lev; Bahnsen, Klaas; Descamps, Helene C.; Demetriadou, Christina; Chan, Jacqueline; Chellappa, Karthikeyani; Cox, Timothy O.; Heyman, Yael; Pather, Sarshan R.; Shoffler, Clarissa; Petucci, Christopher; Shalem, Ophir; Raj, Arjun; Baur, Joseph A.; Snyder, Nathaniel W.; Wellen, Kathryn E.; Levy, Maayan; Seale, Patrick; Li, Mingyao; Thaiss, Christoph A. 分享 收藏 分享 收藏 分享 收藏 Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin function and life spanGarcia, Gilberto; Bar-Ziv, Raz; Averbukh, Maxim; Dasgupta, Nirmalya; Dutta, Naibedya; Zhang, Hanlin; Fan, Wudi; Moaddeli, Darius; Tsui, C. Kimberly; Torres, Toni Castro; Alcala, Athena; Moehle, Erica A. A.; Hoang, Sally; Shalem, Ophir; Adams, Peter D. D.; Thorwald, Max A. A.; Higuchi-Sanabria, Ryo 分享 收藏 Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic CancerBcl-xl强制在胰腺癌缺乏营养的微环境中生存所必需的慢循环状态Sela, Yogev; Li, Jinyang; Maheswaran, Shivahamy; Norgard, Robert; Yuan, Salina; Hubbi, Maimon; Doepner, Miriam; Xu, Jimmy P.; Ho, Elaine S.; Mesaros, Clementina; Sheehan, Colin; Croley, Grace; Muir, Alexander; Blair, Ian A.; Shalem, Ophir; Dang, Chi V.; Stanger, Ben Z. 分享 收藏 Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilizationMoehle, Erica A.; Higuchi-Sanabria, Ryo; Tsui, C. Kimberly; Homentcovschi, Stefan; Tharp, Kevin M.; Zhang, Hanlin; Chi, Hannah; Joe, Larry; Rogers, Mattias de Los Rios; Sahay, Arushi; Kelet, Naame; Benitez, Camila; Bar-Ziv, Raz; Garcia, Gilberto; Shen, Koning; Frankino, Phillip A.; Schinzel, Robert T.; Shalem, Ophir; Dillin, Andrew 分享 收藏 Therapeutic genetic variation revealed in diverse Hsp104 homologsMarch, Zachary M.; Sweeney, Katelyn; Kim, Hanna; Yan, Xiaohui; Castellano, Laura M.; Jackrel, Meredith E.; Lin, JiaBei; Chuang, Edward; Gomes, Edward; Willicott, Corey W.; Michalska, Karolina; Jedrzejczak, Robert P.; Joachimiak, Andrzej; Caldwell, Kim A.; Caldwell, Guy A.; Shalem, Ophir; Shorter, James 分享 收藏 Building an international consortium for tracking coronavirus health status (vol 78, pg 931, 2020)Segal, Eran; Zhang, Feng; Lin, Xihong; King, Gary; Shalem, Ophir; Shilo, Smadar; Allen, William E.; Alquaddoomi, Faisal; Altae-Tran, Han; Anders, Simon; Balicer, Ran; Bauman, Tal; Bonilla, Ximena; Booman, Gisel; Chan, Andrew T.; Cohen, Ori; Coletti, Silvano; Davidson, Natalie; Dor, Yuval; Drew, David A.; Elemento, Olivier; Evans, Georgina; Ewels, Phil; Gale, Joshua; Gavrieli, Amir; Geiger, Benjamin; Grad, Yonatan H.; Greene, Casey S.; Hajirasouliha, Iman; Jerala, Roman; Kahles, Andre; Kallioniemi, Olli; Keshet, Ayya; Kocarev, Ljupco; Landua, Gregory; Meir, Tomer; Muller, Aline; Nguyen, Long H.; Oresic, Matej; Ovchinnikova, Svetlana; Peterson, Hedi; Prodanova, Jana; Rajagopal, Jay; Raetsch, Gunnar; Rossman, Hagai; Rung, Johan; Sboner, Andrea; Sigaras, Alexandros; Spector, Tim; Steinherz, Ron; Stevens, Irene; Vilo, Jaak; Wilmes, Paul 分享 收藏 Building an international consortium for tracking coronavirus health statusSegal, Eran; Zhang, Feng; Lin, Xihong; King, Gary; Shalem, Ophir; Shilo, Smadar; Allen, William E.; Alquaddoomi, Faisal; Altae-Tran, Han; Anders, Simon; Balicer, Ran; Bauman, Tal; Bonilla, Ximena; Booman, Gisel; Chan, Andrew T.; Cohen, Ori; Coletti, Silvano; Davidson, Natalie; Dor, Yuval; Drew, David A.; Elemento, Olivier; Evans, Georgina; Ewels, Phil; Gale, Joshua; Gavrieli, Amir; Geiger, Benjamin; Grad, Yonatan H.; Greene, Casey S.; Hajirasouliha, Iman; Jerala, Roman; Kahles, Andre; Kallioniemi, Olli; Keshet, Ayya; Kocarev, Ljupco; Landua, Gregory; Meir, Tomer; Muller, Aline; Nguyen, Long H.; Oresic, Matej; Ovchinnikova, Svetlana; Peterson, Hedi; Prodanova, Jana; Rajagopal, Jay; Ratsch, Gunnar; Rossman, Hagai; Rung, Johan; Sboner, Andrea; Sigaras, Alexandros; Spector, Tim; Steinherz, Ron; Stevens, Irene; Vilo, Jaak; Wilmes, Paul 分享 收藏 Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction白血病死亡受体信号受损通过诱导CAR T细胞功能障碍导致抗原非依赖性耐药Singh, Nathan; Lee, Yong Gu; Shestova, Olga; Ravikumar, Pranali; Hayer, Katharina E.; Hong, Seok Jae; Lu, Xueqing Maggie; Pajarillo, Raymone; Agarwal, Sangya; Kuramitsu, Shunichiro; Orlando, Elena J.; Mueller, Karen Thudium; Berger, Shelley L.; Shalem, Ophir; Weitzman, Matthew D.; Frey, Noelle V.; Maude, Shannon L.; Grupp, Stephan A.; June, Carl H.; Gill, Saar; Ruella, Marco 分享 收藏 
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