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C

Christopher A. Vakulskas

integrated dna technologies idt
H指数:33
被引数:5,517

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Reprogramming site-specific retrotransposon activity to new DNA sites

将位点特异性逆转座子活性重编程至新的DNA位点

NATURE
IF48.5
2025-04-091
PRE
Fell, Christopher W.; Villiger, Lukas; Lim, Justin; Hiraizumi, Masahiro; Tagliaferri, Dario; Yarnall, Matthew T. N.; Lee, Anderson; Jiang, Kaiyi; Kayabolen, Alisan; Krajeski, Rohan N.; Schmitt-Ulms, Cian; Ramani, Harsh; Yousef, Sarah M.; Roberts, Nathaniel; Vakulskas, Christopher A.; Nishimasu, Hiroshi; Abudayyeh, Omar O.; Gootenberg, Jonathan S.
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency

基因校正的RAG2-SCID人造血干细胞恢复V(D)J-重组酶和拯救淋巴缺陷

BLOOD ADVANCES
IF7.1
2024-04-091
OAAI
Pavel-Dinu, Mara; Gardner, Cameron L.; Nakauchi, Yusuke; Kawai, Tomoki; Delmonte, Ottavia M.; Palterer, Boaz; Bosticardo, Marita; Pala, Francesca; Viel, Sebastien; Malech, Harry L.; Ghanim, Hana Y.; Bode, Nicole M.; Kurgan, Gavin L.; Detweiler, Angela M.; Vakulskas, Christopher A.; Neff, Norma F.; Sheikali, Adam; Menezes, Sherah T.; Chrobok, Jade; Gonzalez, Elaine M. Hernandez; Majeti, Ravindra; Notarangelo, Luigi D.; Porteus, Matthew H.
Propensity of Patient-Derived iPSCs for Retinal Differentiation: Implications for Autologous Cell Replacement

患者来源的ipsc对视网膜分化的倾向: 对自体细胞替代的影响

STEM CELLS TRANSLATIONAL MEDICINE
IF4.9
2023-05-238
OAAI
Cooke, Jessica A.; Voigt, Andrew P.; Collingwood, Michael A.; Stone, Nicholas E.; Whitmore, S. Scott; DeLuca, Adam P.; Burnight, Erin R.; Anfinson, Kristin R.; Vakulskas, Christopher A.; Reutzel, Austin J.; Daggett, Heather T.; Andorf, Jeaneen L.; Stone, Edwin M.; Mullins, Robert F.; Tucker, Budd A.
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

使用CRISPR指导的整合酶在没有双链DNA切割的情况下拖放大序列的基因组插入

NATURE BIOTECHNOLOGY
IF41.7
2022-11-24197
OA
Yarnall, Matthew T. N.; Ioannidi, Eleonora I.; Schmitt-Ulms, Cian; Krajeski, Rohan N.; Lim, Justin; Villiger, Lukas; Zhou, Wenyuan; Jiang, Kaiyi; Garushyants, Sofya K.; Roberts, Nathaniel; Zhang, Liyang; Vakulskas, Christopher A.; Walker, John A. I. I. I. I.; Kadina, Anastasia P.; Zepeda, Adrianna E.; Holden, Kevin; Ma, Hong; Xie, Jun; Gao, Guangping; Foquet, Lander; Bial, Greg; Donnelly, Sara K.; Miyata, Yoshinari; Radiloff, Daniel R.; Henderson, Jordana M.; Ujita, Andrew; Abudayyeh, Omar O.; Gootenberg, Jonathan S.
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines (vol 12, 3908, 2021)
NATURE COMMUNICATIONS
IF15.7
2021-07-193
OAAI
Zhang, Liyang; Zuris, John A.; Viswanathan, Ramya; Edelstein, Jasmine N.; Turk, Rolf; Thommandru, Bernice; Rube, H. Tomas; Glenn, Steve E.; Collingwood, Michael A.; Bode, Nicole M.; Beaudoin, Sarah F.; Lele, Swarali; Scott, Sean N.; Wasko, Kevin M.; Sexton, Steven; Borges, Christopher M.; Schubert, Mollie S.; Kurgan, Gavin L.; McNeill, Matthew S.; Fernandez, Cecilia A.; Myer, Vic E.; Morgan, Richard A.; Behlke, Mark A.; Vakulskas, Christopher A.
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

AsCas12a超核酸酶促进治疗细胞药物的快速生成

NATURE COMMUNICATIONS
IF15.7
2021-06-2377
OAAI
Zhang, Liyang; Zuris, John A.; Viswanathan, Ramya; Edelstein, Jasmine N.; Turk, Rolf; Thommandru, Bernice; Rube, H. Tomas; Glenn, Steve E.; Collingwood, Michael A.; Bode, Nicole M.; Beaudoin, Sarah F.; Lele, Swarali; Scott, Sean N.; Wasko, Kevin M.; Sexton, Steven; Borges, Christopher M.; Schubert, Mollie S.; Kurgan, Gavin L.; McNeill, Matthew S.; Fernandez, Cecilia A.; Myer, Vic E.; Morgan, Richard A.; Behlke, Mark A.; Vakulskas, Christopher A.
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-06-1689
OA
Lattanzi, Annalisa; Camarena, Joab; Lahiri, Premanjali; Segal, Helen; Srifa, Waracharee; Vakulskas, Christopher A.; Frock, Richard L.; Kenrick, Josefin; Lee, Ciaran; Talbott, Narae; Skowronski, Jason; Cromer, M. Kyle; Charlesworth, Carsten T.; Bak, Rasmus O.; Mantri, Sruthi; Bao, Gang; DiGiusto, David; Tisdale, John; Wright, J. Fraser; Bhatia, Neehar; Roncarolo, Maria Grazia; Dever, Daniel P.; Porteus, Matthew H.
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
NATURE MEDICINE
IF50
2021-03-1853
OAAI
Cromer, M. Kyle; Camarena, Joab; Martin, Renata M.; Lesch, Benjamin J.; Vakulskas, Christopher A.; Bode, Nicole M.; Kurgan, Gavin; Collingwood, Michael A.; Rettig, Garrett R.; Behlke, Mark A.; Lemgart, Viktor T.; Zhang, Yankai; Goyal, Ankush; Zhao, Feifei; Ponce, Ezequiel; Srifa, Waracharee; Bak, Rasmus O.; Uchida, Naoya; Majeti, Ravindra; Sheehan, Vivien A.; Tisdale, John F.; Dever, Daniel P.; Porteus, Matthew H.
Identification of preexisting adaptive immunity to Cas9 proteins in humans
NATURE MEDICINE
IF50
2019-01-28663
OAAI
Charlesworth, Carsten T.; Deshpande, Priyanka S.; Dever, Daniel P.; Camarena, Joab; Lemgart, Viktor T.; Cromer, M. Kyle; Vakulskas, Christopher A.; Collingwood, Michael A.; Zhang, Liyang; Bode, Nicole M.; Behlke, Mark A.; Dejene, Beruh; Cieniewicz, Brandon; Romano, Rosa; Lesch, Benjamin J.; Gomez-Ospina, Natalia; Mantri, Sruthi; Pavel-Dinu, Mara; Weinberg, Kenneth I.; Porteus, Matthew H.
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
NATURE MEDICINE
IF50
2018-08-06595
OAAI
Vakulskas, Christopher A.; Dever, Daniel P.; Rettig, Garrett R.; Turk, Rolf; Jacobi, Ashley M.; Collingwood, Michael A.; Bode, Nicole M.; McNeill, Matthew S.; Yan, Shuqi; Camarena, Joab; Lee, Ciaran M.; Parka, So Hyun; Wiebking, Volker; Bak, Rasmus O.; Gomez-Ospina, Natalia; Pavel-Dinu, Mara; Sun, Wenchao; Bao, Gang; Porteus, Matthew H.; Behlke, Mark A.

研究方向

暂未获取到该数据
M
Mark A. Behlke
H 指数:63论文数:196被引数:1.6万
M
Matthew H. Porteus
H 指数:72论文数:339被引数:2.4万
N
Nicole M. Bode
H 指数:11论文数:17被引数:2,434
M
Michael A. Collingwood
H 指数:14论文数:16被引数:2,846
L
Liyang Zhang
H 指数:43论文数:284被引数:8,115
T
Tony Romeo
H 指数:63论文数:144被引数:1.4万
M
M. Kyle Cromer
H 指数:15论文数:45被引数:2,339
G
Gavin Kurgan
H 指数:15论文数:38被引数:1,349
D
Daniel P. Dever
H 指数:23论文数:66被引数:4,742
J
Joab Camarena
H 指数:15论文数:35被引数:3,955