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Paula Keskula

broad institute of mit and harvard
H指数:9
被引数:2,642

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A compendium of next-generation patient-derived models for diverse cancers

用于多种癌症的下一代患者来源模型汇编

Nature
IF48.5
2026-08-050
OA
Dina ElHarouni; Mushriq Al-Jazrawe; Seongmin Choi; Merve Dede; Toshinori Hinoue; Sean A. Misek; Heeju Noh; Luca Zanella; Yuen-Yi Tseng; Hayley E. Francies; Dennis Plenker; Cindy W. Kyi; Julyann Perez-Mayoral; Megan J. Stine; Eva Tonsing-Carter; Rachana Agarwal; Jean Claude Zenklusen; James M. Clinton; Jennifer M. Shelton; Timothy R. Chu; William F. Hooper; Xavi Loinaz; Paula Keskula; Jordan Tagle; Peyton C. Kuhlers; Bahar Tercan; Sylvia F. Boj; Alessandro Vasciaveo; Lorenzo Tomassoni; James M. Crawford; Shawna Walsh; Claire Sinai; Sonam Bhatia; Priya Sridevi; Hardik Patel; Maria Antonietta Cerone; Kyle Ellrott; Calvin J. Kuo; Olivier Elemento; Semir Beyaz; Vincenzo Corbo; David L. Spector; Rameen Beroukhim; Martin L. Ferguson; Andrew D. Cherniack; Peter W. Laird; Nicolas Robine; Andrew McPherson; Katherine A. Hoadley; Mathew J. Garnett; David A. Tuveson; Andrea Califano; Paul T. Spellman; Keith L. Ligon; Daniela S. Gerhard; Louis M. Staudt; Jesse S. Boehm
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin
COMMUNICATIONS BIOLOGY
IF5.1
2024-04-080
OAAI
Mittal, Karuna; Cooper, Garrett W.; Lee, Benjamin P.; Su, Yongdong; Skinner, Katie T.; Shim, Jenny; Jonus, Hunter C.; Kim, Won Jun; Doshi, Mihir; Almanza, Diego; Kynnap, Bryan D.; Christie, Amanda L.; Yang, Xiaoping; Cowley, Glenn S.; Leeper, Brittaney A.; Morton, Christopher L.; Dwivedi, Bhakti; Lawrence, Taylor; Rupji, Manali; Keskula, Paula; Meyer, Stephanie; Clinton, Catherine M.; Bhasin, Manoj; Crompton, Brian D.; Tseng, Yuen-Yi; Bohm, Jesse S.; Ligon, Keith L.; Root, David E.; Murphy, Andrew J.; Weinstock, David M.; Gokhale, Prafulla C.; Spangle, Jennifer M.; Rivera, Miguel N.; Mullen, Elizabeth A.; Stegmaier, Kimberly; Goldsmith, Kelly C.; Hahn, William C.; Hong, Andrew L.
The landscape of cancer cell line metabolism
NATURE MEDICINE
IF50
2019-05-08342
OAAI
Li, Haoxin; Ning, Shaoyang; Ghandi, Mahmoud; Kryukov, Gregory V.; Gopal, Shuba; Deik, Amy; Souza, Amanda; Pierce, Kerry; Keskula, Paula; Hernandez, Desiree; Ann, Julie; Shkoza, Dojna; Apfel, Verena; Zou, Yilong; Vazquez, Francisca; Barretina, Jordi; Pagliarini, Raymond A.; Galli, Giorgio G.; Root, David E.; Hahn, William C.; Tsherniak, Aviad; Giannakis, Marios; Schreiber, Stuart L.; Clish, Clary B.; Garraway, Levi A.; Sellers, William R.
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
ELIFE
IF0
2019-03-1237
OA
Hong, Andrew L.; Tseng, Yuen-Yi; Wala, Jeremiah A.; Kim, Won-Jun; Kynnap, Bryan D.; Doshi, Mihir B.; Kugener, Guillaume; Sandoval, Gabriel J.; Howard, Thomas P.; Li, Ji; Yang, Xiaoping; Tillgren, Michelle; Ghandi, Mahmhoud; Sayeed, Abeer; Deasy, Rebecca; Ward, Abigail; McSteen, Brian; Labella, Katherine M.; Keskula, Paula; Tracy, Adam; Connor, Cora; Clinton, Catherine M.; Church, Alanna J.; Crompton, Brian D.; Janeway, Katherine A.; Van Hare, Barbara; Sandak, David; Gjoerup, Ole; Bandopadhayay, Pratiti; Clemons, Paul A.; Schreiber, Stuart L.; Root, David E.; Gokhale, Prafulla C.; Chi, Susan N.; Mullen, Elizabeth A.; Roberts, Charles W. M.; Kadoch, Cigall; Beroukhim, Rameen; Ligon, Keith L.; Boehm, Jesse S.; Hahn, William C.
Identification of Druggable Targets through Functional Multi-Omics in Renal Medullary Carcinoma
MOLECULAR CANCER THERAPEUTICS
IF5.5
2017-10-020
PRE
Hong, Andrew L.; Tseng, Yuen-Yi; Kynnap, Bryan D.; Doshi, Mihir B.; Sandoval, Gabriel; Oh, Coyin; Sayeed, Abeer; Shubhroz, Gill; Church, Alanna J.; Keskula, Paula; Peng, Anson; Clemons, Paul A.; Tsherniak, Aviad; Vazquez, Francisca; Rodriguez-Galindo, Carlos; Janeway, Katherine A.; Garraway, Levi A.; Schreiber, Stuart L.; Root, David E.; Mullen, Elizabeth; Stegmaier, Kimberly; Kadoch, Cigall; Roberts, Charles W. M.; Boehm, Jesse S.; Hahn, William C.
Accelerating prediction of pediatric and rare cancer vulnerabilities using next-generation cancer models
CANCER RESEARCH
IF16.6
2017-07-010
PRE
Tseng, Yuen-Yi; Hong, Andrew; Keskula, Paula; Gill, Shubhroz; Cheah, Jaime; Kryukov, Grigoriy; Tsherniak, Aviad; Vazquez, Francisca; Cowley, Glenn; Alkhairy, Sahar; Oh, Coyin; Peng, Anson; Deasy, Rebecca; Sayeed, Abeer; Ronning, Peter; Ng, Samuel; Corsello, Steven; Painter, Corrie; Sandak, David; Garraway, Levi; Rubin, Mark; Kuo, Calvin; Puram, Sidharth; Weinstock, David; Bass, Adam; Wagle, Nikhil; Ligon, Keith; Janeway, Katherine; Root, David; Schreiber, Stuart; Clemons, Paul; Shamji, Aly; Shamji, Aly; Hahn, William; Golub, Todd; Boehm, Jesse
Accelerating prediction of tumor vulnerabilities using next-generation cancer models
CANCER RESEARCH
IF16.6
2016-07-150
PRE
Tseng, Yuen-Yi; Hong, Andrew; Keskula, Paula; Gill, Shubhroz; Cheah, Jaime; Kryukov, Grigoriy; Tsherniak, Aviad; Vazquez, Francisca; Cowley, Glenn; Oh, Coyin; Peng, Anson; Sayeed, Abeer; Deasy, Rebecca; Ronning, Peter; Kantoff, Philip; Garraway, Levi; Rubin, Mark; Kuo, Calvin; Puram, Sidharth; Gazdar, Adi; Dela Cruz, Filemon; Bass, Adam; Wagle, Nikhil; Ligon, Keith; Janeway, Katherine; Root, David; Schreiber, Stuart; Clemons, Paul; Shamji, Aly; Hahn, William; Golub, Todd; Boehm, Jesse S.
Integrated genetic and pharmacologic interrogation of rare cancers
NATURE COMMUNICATIONS
IF15.7
2016-06-2250
OAAI
Hong, Andrew L.; Tseng, Yuen-Yi; Cowley, Glenn S.; Jonas, Oliver; Cheah, Jaime H.; Kynnap, Bryan D.; Doshi, Mihir B.; Oh, Coyin; Meyer, Stephanie C.; Church, Alanna J.; Gill, Shubhroz; Bielski, Craig M.; Keskula, Paula; Imamovic, Alma; Howell, Sara; Kryukov, Gregory V.; Clemons, Paul A.; Tsherniak, Aviad; Vazquez, Francisca; Crompton, Brian D.; Shamji, Alykhan F.; Rodriguez-Galindo, Carlos; Janeway, Katherine A.; Roberts, Charles W. M.; Stegmaier, Kimberly; van Hummelen, Paul; Cima, Michael J.; Langer, Robert S.; Garraway, Levi A.; Schreiber, Stuart L.; Root, David E.; Hahn, William C.; Boehm, Jesse S.
Towards precision functional genomics via next-generation functional mapping of cancer variants
CANCER RESEARCH
IF16.6
2015-11-150
PRE
Berger, Alice H.; Kim, Eejung; Brooks, Angela; Ilic, Nina; Shrestha, Yashaswi; Tseng, Yuen-Yi; Wu, Xiaoyun; Zou, Lihua; Kamburov, Atanas; Yang, Xiaoping; Zhu, Cong; Keskula, Paula; Seepo, Sara; Hong, Andrew; Kantoff, Philip; Ligon, Keith L.; Garraway, Levi A.; Doench, John G.; Root, David E.; Meyerson, Matthew; Hahn, William C.; Getz, Gad; Golub, Todd R.; Boehm, Jesse S.
Towards precision functional genomics via next-generation functional mapping of cancer variants
CANCER RESEARCH
IF16.6
2015-08-010
PRE
Bergen, Alice; Kim, Eejung; Brooks, Angela; Shrestha, Yashaswi; Tseng, Yuen-Yi; Wu, Xiaoyun; Ilic, Nina; Zou, Lihua; Kamburov, Atanas; Yang, Xiaoping; Zhu, Cong; Keskula, Paula; Seepo, Sara; Hong, Andrew; Doench, John; Subramanian, Aravind; Ligon, Keith; Kantoff, Philip; Janeway, Katherine; Garraway, Levi; Root, David; Golub, Todd; Meyerson, Matthew; Hahn, William; Getz, Gad; Boehm, Jesse

研究方向

暂未获取到该数据
J
Jesse S. Boehm
H 指数:59论文数:332被引数:4.2万
A
Andrew L. Hong
H 指数:24论文数:148被引数:3,502
W
William C. Hahn
H 指数:147论文数:1,091被引数:10.1万
D
David E. Root
H 指数:106论文数:815被引数:6.9万
Y
Yuen‐Yi Tseng
H 指数:15论文数:106被引数:3,305
K
Keith L. Ligon
H 指数:113论文数:1,205被引数:5.0万
L
Levi A. Garraway
H 指数:147论文数:1,018被引数:14.8万
K
Katherine A. Janeway
H 指数:53论文数:466被引数:1.2万
S
Stuart L. Schreiber
H 指数:166论文数:1,312被引数:13.2万
F
Francisca Vázquez
H 指数:76论文数:520被引数:3.3万