Jay L. Degen - Publications, H-index & Citations

Jay L. Degen

Cornell University

71H指数

200论文数

1.9W被引数

收录论文 65

发表时间

Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection

PLOS PATHOGENS

IF4.9

2022-01-18

OAAI

Negron, Oscar; Hur, Woosuk S.; Prasad, Joni; Paul, David S.; Rowe, Sarah E.; Degen, Jay L.; Abrahams, Sara R.; Antoniak, Silvio; Conlon, Brian P.; Bergmeier, Wolfgang; Hook, Magnus; Flick, Matthew J.

Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-12-28

OAAI

Prasad, Joni M.; Negron, Oscar; Du, Xinli; Mullins, Eric S.; Palumbo, Joseph S.; Gilbertie, Jessica M.; Hook, Magnus; Grover, Steven P.; Pawlinski, Rafal; Mackman, Nigel; Degen, Jay L.; Flick, Matthew J.

Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal

PLOS GENETICS

IF3.7

2019-03-14

OAAI

Gould, Thomas W.; Dominguez, Bertha; de Winter, Fred; Yeo, Gene W.; Liu, Patrick; Sundararaman, Balaji; Stark, Thomas; Vu, Anthony; Degen, Jay L.; Lin, Weichun; Lee, Kuo-Fen

A fibrin biofilm covers blood clots and protects from microbial invasion 纤维蛋白生物膜覆盖血凝块并防止微生物入侵

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2018-06-25

101

OAAI

Macrae, Fraser L.; Duval, Cedric; Papareddy, Praveen; Baker, Stephen R.; Yuldasheva, Nadira; Kearney, Katherine J.; McPherson, Helen R.; Asquith, Nathan; Konings, Joke; Casini, Alessandro; Degen, Jay L.; Connell, Simon D.; Philippou, Helen; Wolberg, Alisa S.; Herwald, Heiko; Ariens, Robert A. S.

Male-specific cardiac pathologies in mice lacking either the A or B subunit of factor XIII

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-11-24

PREAI

Souri, Masayoshi; Koseki-Kuno, Shiori; Takeda, Naoki; Yamakawa, Mitsunori; Takeishi, Yasuchika; Degen, Jay L.; Ichinose, Akitada

Plasmin Prevents Dystrophic Calcification After Muscle Injury

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2016-08-17

OAAI

Mignemi, Nicholas A.; Yuasa, Masato; Baker, Courtney E.; Moore, Stephanie N.; Ihejirika, Rivka C.; Oelsner, William K.; Wallace, Christopher S.; Yoshii, Toshitaka; Okawa, Atsushi; Revenko, Alexey S.; MacLeod, A. Robert; Bhattacharjee, Gourab; Barnett, Joey V.; Schwartz, Herbert S.; Degen, Jay L.; Flick, Matthew J.; Cates, Justin M.; Schoenecker, Jonathan G.

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

NATURE COMMUNICATIONS

IF15.7

2015-09-10

245

OAAI

Ryu, Jae Kyu; Petersen, Mark A.; Murray, Sara G.; Baeten, Kim M.; Meyer-Franke, Anke; Chan, Justin P.; Vagena, Eirini; Bedard, Catherine; Machado, Michael R.; Coronado, Pamela E. Rios; Prod'homme, Thomas; Charo, Israel F.; Lassmann, Hans; Degen, Jay L.; Zamvil, Scott S.; Akassoglou, Katerina

Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification (vol 125, pg 3117, 2015)

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2015-09-01

OAAI

Yuasa, Masato; Mignemi, Nicholas A.; Nyman, Jeffry S.; Duvall, Craig L.; Schwartz, Herbert S.; Okawa, Atsushi; Yoshii, Toshitaka; Bhattacharjee, Gourab; Zhao, Chenguang; Bible, Jesse E.; Obremskey, William T.; Flick, Matthew J.; Degen, Jay L.; Barnett, Joey V.; Cates, Justin M. M.; Schoenecker, Jonathan G.

Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2015-07-27

OAAI

Fibrin Accumulation Secondary to Loss of Plasmin-Mediated Fibrinolysis Drives Inflammatory Osteoporosis in Mice

ARTHRITIS & RHEUMATOLOGY

IF10.9

2014-07-28

OAAI

Cole, Heather A.; Ohba, Tetsuro; Nyman, Jeffry S.; Hirotaka, Haro; Cates, Justin M. M.; Flick, Matthew J.; Degen, Jay L.; Schoenecker, Jonathan G.

Factor XIII activity mediates red blood cell retention in venous thrombi

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2014-07-01

172

OAAI

Aleman, Maria M.; Byrnes, James R.; Wang, Jian-Guo; Tran, Reginald; Lam, Wilbur A.; Di Paola, Jorge; Mackman, Nigel; Degen, Jay L.; Flick, Matthew J.; Wolberg, Alisa S.

Plasminogen Is a Joint-Specific Positive or Negative Determinant of Arthritis Pathogenesis in Mice

ARTHRITIS & RHEUMATOLOGY

IF10.9

2014-05-27

OAAI

Raghu, Harini; Jone, Alice; Cruz, Carolina; Rewerts, Cheryl L.; Frederick, Malinda D.; Thornton, Sherry; Degen, Jay L.; Flick, Matthew J.

Early detection of thrombin activity in neuroinflammatory disease

ANNALS OF NEUROLOGY

IF7.7

2014-02-24

OAAI

Davalos, Dimitrios; Baeten, Kim M.; Whitney, Michael A.; Mullins, Eric S.; Friedman, Beth; Olson, Emilia S.; Ryu, Jae Kyu; Smirnoff, Dimitri S.; Petersen, Mark A.; Bedard, Catherine; Degen, Jay L.; Tsien, Roger Y.; Akassoglou, Katerina

Role of fibrinogen in acute ischemic kidney injury

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY

IF3.4

2013-09-01

PREAI

Soerensen-Zender, I.; Rong, S.; Susnik, N.; Lange, J.; Gueler, F.; Degen, J. L.; Melk, A.; Haller, H.; Schmitt, R.

Fibrinogen/CR3 signaling induces demyelination by promoting Th1 cell differentiation and peripheral macrophage recruitment into the CNS

CYTOKINE

IF3.7

2013-09-01

PREAI

Ryu, Jae Kyu; Baeten, Kim M.; Petersen, Mark A.; Murray, Sara G.; Meyer-Franke, Anke; Davalos, Dimitrios; Bedard, Catherine; Prod'homme, Thomas; Charo, Israel F.; Lassmann, Hans; Degen, Jay L.; Zamvil, Scott S.; Akassoglou, Katerina

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

NATURE COMMUNICATIONS

IF15.7

2012-11-27

490

OAAI

Davalos, Dimitrios; Ryu, Jae Kyu; Merlini, Mario; Baeten, Kim M.; Le Moan, Natacha; Petersen, Mark A.; Deerinck, Thomas J.; Smirnoff, Dimitri S.; Bedard, Catherine; Hakozaki, Hiroyuki; Murray, Sara Gonias; Ling, Jennie B.; Lassmann, Hans; Degen, Jay L.; Ellisman, Mark H.; Akassoglou, Katerina

Hemostatic factors, innate immunity and malignancy

THROMBOSIS RESEARCH

IF3.4

2012-04-01

PREAI

Degen, Jay L.; Palumbo, Joseph S.

Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the M2 leukocyte integrin receptor

HUMAN MOLECULAR GENETICS

IF3.2

2012-03-01

OAAI

Vidal, Berta; Ardite, Esther; Suelves, Monica; Ruiz-Bonilla, Vanessa; Janue, Anna; Flick, Matthew J.; Degen, Jay L.; Serrano, Antonio L.; Munoz-Canoves, Pura

Fibrinogen, acting as a mitogen for tubulointerstitial fibroblasts, promotes renal fibrosis 纤维蛋白原作为肾小管间质成纤维细胞的有丝分裂原，促进肾纤维化

KIDNEY INTERNATIONAL

IF12.6

2011-11-01

OAAI

Soerensen, Inga; Susnik, Nathan; Inhester, Therese; Degen, Jay L.; Melk, Anette; Haller, Herrmann; Schmitt, Roland

Binding of Efb from Staphylococcus aureus to Fibrinogen Blocks Neutrophil Adherence

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-03-01

OAAI

Ko, Ya-Ping; Liang, Xiaowen; Smith, C. Wayne; Degen, Jay L.; Hoeoek, Magnus

研究方向