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Megha Chandrashekhar

university health network toronto

H指数:10

被引数:3,384

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Triclosan concurrently inhibits UGT and CYP enzymes but shows high selectivity toward CYP2C19

三氯生同时抑制UGT和CYP酶，但对CYP2C19表现出高度选择性。

Medicinal Chemistry Research

IF3.1

2025-10-290

OA

Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux (Aug, 10.1038/s41589-022-01146-9, 2022)

NATURE CHEMICAL BIOLOGY

IF13.7

2022-08-240

OA

Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux

NATURE CHEMICAL BIOLOGY

IF13.7

2022-08-154

PRE

Direct interaction between CEP85 and STIL mediates PLK4-driven directed cell migration

JOURNAL OF CELL SCIENCE

IF3.6

2020-04-2313

OA

Forward genetic screen in human podocytes identifies diphthamide biosynthesis genes as regulators of adhesion

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY

IF3.4

2019-12-016

OAAI

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

NATURE MEDICINE

IF50

2016-11-21248

PREAI

Identification of cancer vulnerabilities to metabolic perturbation using genome wide CRISPR screens

CANCER RESEARCH

IF16.6

2016-07-150

PRE

Cytokinetic effects of Wee1 disruption in pancreatic cancer

IF3.4

2016-03-0913

OA

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2013-10-0886

OAAI

Vizeacoumar, Franco J.; Arnold, Roland; Vizeacoumar, Frederick S.; Chandrashekhar, Megha; Buzina, Alla; Young, Jordan T. F.; Kwan, Julian H. M.; Sayad, Azin; Mero, Patricia; Lawo, Steffen; Tanaka, Hiromasa; Brown, Kevin R.; Baryshnikova, Anastasia; Mak, Anthony B.; Fedyshyn, Yaroslav; Wang, Yadong; Brito, Glauber C.; Kasimer, Dahlia; Makhnevych, Taras; Ketela, Troy; Datti, Alessandro; Babu, Mohan; Emili, Andrew; Pelletier, Laurence; Wrana, Jeff; Wainberg, Zev; Kim, Philip M.; Rottapel, Robert; O'Brien, Catherine A.; Andrews, Brenda; Boone, Charles; Moffat, Jason