Bruce R. Conklin - Publications, H-index & Citations

Bruce R. Conklin

University of California System

77H指数

257论文数

2.5W被引数

收录论文 99

发表时间

Monitoring biological effects of somatic cell genome editing 体细胞基因组编辑的生物学效应监测

Nature Reviews Genetics

IF52

2026-01-13

PREAI

Benjamin S. Freedman; Jeff W. M. Bulte; Bruce R. Conklin; Luke M. Judge; Melinda R. Dwinell; Aron M. Geurts; Madeleine J. Sitton; Vineet Mahajan; Samira Kiani; Charles A. Gersbach; Mo R. Ebrahimkhani; John J. Kelly; John A. Ronald; Ryuji Morizane; Navin Gupta; Ali Shakeri-Zadeh; Nicole Vo; Krishanu Saha; Shivani Saxena; David M. Gamm; Divya Sinha; Alice F. Tarantal; Moriel Vandsburger; Azusa Matsubara; Hongxia Fu; Shengdar Q. Tsai

Generation of WTD, a control human iPSC line for genetic research WTD的生成，一种用于遗传研究的控制性人类iPSC细胞系

STEM CELL RESEARCH

IF0.7

2025-12-01

OAAI

Macklin, Bria L.; Runyon, Wendy V.; Feliciano, Carissa M.; Dierks, Philip H.; Kelly, Kaitlin R.; Watry, Hannah L.; Judge, Luke M.; Conklin, Bruce R.; Sequencing, Targeted Sanger

Haplotype editing with CRISPR/Cas9 as a therapeutic approach for dominant-negative missense mutations in NEFL 利用CRISPR/Cas9进行单倍型编辑，作为一种针对NEFL基因显性负性错义突变的治疗方法。

Molecular Therapy

IF12

2025-11-19

PREAI

Poorvi H. Dua; Bazilco M.J. Simon; Chiara B.E. Marley; Carissa M. Feliciano; Hannah L. Watry; Quinn T. Cowan; Dylan Steury; Abin Abraham; Erin N. Gilbertson; Grace D. Ramey; John A. Capra; Bruce R. Conklin; Luke M. Judge

Characterizing and controlling CRISPR repair outcomes in nondividing human cells 表征和控制非分裂人类细胞中的CRISPR修复结果

Nature Communications

IF15.7

2025-11-17

OAAI

Gokul N. Ramadoss; Samali J. Namaganda; Manasi M. Kumar; Jennifer R. Hamilton; Rohit Sharma; Karena G. Chow; Luke A. Workley; Bria L. Macklin; Mengyuan Sun; Alvin S. Ha; Jia-Cheng Liu; Christof Fellmann; Hannah L. Watry; Philip H. Dierks; Rudra S. Bose; Julianne Jin; Barbara S. Perez; Cindy R. Sandoval Espinoza; Madeline P. Matia; Serena H. Lu; Luke M. Judge; Brian R. Shy; Andre Nussenzweig; Britt Adamson; Niren Murthy; Jennifer A. Doudna; Martin Kampmann; Bruce R. Conklin

A microphysiological system for screening lipid nanoparticle−mRNA complexes predicts in vivo heart transfection efficacy 一种微生理系统用于筛选脂质纳米颗粒−mRNA复合物，可预测体内心脏转染效率

Nature Biomedical Engineering

IF26.6

2025-11-03

PREAI

Gabriel Neiman; Mauro W. Costa; Hesong Han; Sheng Zhao; Tammy K. Ng; Brian Siemons; Tomohiro Nishino; Yu Huang; Shyam Lal; Kenneth Wu; Luke M. Judge; Bruce R. Conklin; Deepak Srivastava; Niren Murthy; Kevin E. Healy

Permittivity tensor imaging: modular label-free imaging of 3D dry mass and 3D orientation at high resolution

NATURE METHODS

IF32.1

2024-06-18

OAAI

Yeh, Li-Hao; Ivanov, Ivan E.; Chandler, Talon; Byrum, Janie R.; Chhun, Bryant B.; Guo, Syuan-Ming; Foltz, Cameron; Hashemi, Ezzat; Perez-Bermejo, Juan A.; Wang, Huijun; Yu, Yanhao; Kazansky, Peter G.; Conklin, Bruce R.; Han, May H.; Mehta, Shalin B.

Advances and challenges in modeling inherited peripheral neuropathies using iPSCs 使用iPSCs对遗传性周围神经病进行建模的进展和挑战

EXPERIMENTAL AND MOLECULAR MEDICINE

IF12.9

2024-06-03

OAAI

Van Lent, Jonas; Prior, Robert; Siles, Gonzalo Perez; Cutrupi, Anthony N.; Kennerson, Marina L.; Vangansewinkel, Tim; Wolfs, Esther; Mukherjee-Clavin, Bipasha; Nevin, Zachary; Judge, Luke; Conklin, Bruce; Tyynismaa, Henna; Clark, Alex J.; Bennett, David L.; Van Den Bosch, Ludo; Saporta, Mario; Timmerman, Vincent

Reversal of C9orf72 mutation- induced transcriptional dysregulation and pathology in cultured human neurons by allele- specific excision

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-15

OAAI

Sachdev, Aradhana; Gill, Kamaljot; Sckaff, Maria; Birk, Alisha M.; Arogundade, Olubankole Aladesuyi; Brown, Katherine A.; Chouhan, Runvir S.; Issagholian-Lewin, Patrick Oliver; Patel, Esha; Watry, Hannah L.; Bernardi, Mylinh T.; Keough, Kathleen C.; Tsai, Yu-Chih; Smith, Alec Simon Tulloch; Conklin, Bruce R.; Clelland, Claire Dudley

Give heart cells a beat: An interactive museum exhibit that synchronizes stem cell-derived cardiomyocytes to visitors' heartbeat

STEM CELL REPORTS

IF5.1

2024-03-01

OAAI

Perez-Bermejo, Juan A.; Reisman, Samuel J.; Ma, Joyce; Carrison-Stone, Dana; Cerrito, Chris; Ribeiro, Alexandre J. S.; Conklin, Bruce R.; Yu, Kristina

Validated assays for the quantification of C9orf72 human pathology

SCIENTIFIC REPORTS

IF3.9

2024-01-08

OAAI

Salomonsson, S. E.; Maltos, A. M.; Gill, K.; Arogundade, O. Aladesuyi; Brown, K. A.; Sachdev, A.; Sckaff, M.; Lam, K. J. K.; Fisher, I. J.; Chouhan, R. S.; Van Laar, V. S.; Marley, C. B.; Mclaughlin, I.; Bankiewicz, K. S.; Tsai, Y. -c.; Conklin, B. R.; Clelland, C. D.

Functional analysis of a common BAG3 allele associated with protection from heart failure

cardiovascular research

IF10.8

2023-06-26

OAAI

Perez-Bermejo, Juan A.; Judge, Luke M.; Jensen, Christina L.; Wu, Kenneth; Watry, Hannah L.; Truong, Annie; Ho, Jaclyn J.; Carter, Matthew; Runyon, Wendy V.; Kaake, Robyn M.; Pulido, Ernst H.; Mandegar, Mohammad A.; Swaney, Danielle L.; So, Po-Lin; Krogan, Nevan J.; Conklin, Bruce R.

Evaluation of CRISPR/Cas9 exon-skipping vector for choroideremia using human induced pluripotent stem cell-derived RPE

JOURNAL OF GENE MEDICINE

IF2.2

2022-12-04

OAAI

Iwagawa, Toshiro; Masumoto, Hiroki; Tabuchi, Hitoshi; Tani, Kenzaburo; Conklin, Bruce R.; Watanabe, Sumiko

A reference human induced pluripotent stem cell line for collaborative studies 用于合作研究的参考人类诱导多能干细胞系

CELL STEM CELL

IF20.4

2022-12-01

OAAI

Pantazis, Caroline B.; Yang, Andrian; Lara, Erika; McDonough, Justin A.; Blauwendraat, Cornelis; Peng, Lirong; Oguro, Hideyuki; Kanaujiya, Jitendra; Zou, Jizhong; Sebesta, David; Pratt, Gretchen; Cross, Erin; Blockwick, Jeffrey; Buxton, Philip; Kinner-Bibeau, Lauren; Medura, Constance; Tompkins, Christopher; Hughes, Stephen; Santiana, Marianita; Faghri, Faraz; Nalls, Mike A.; Vitale, Daniel; Ballard, Shannon; Qi, Yue A.; Ramos, Daniel M.; Anderson, Kailyn M.; Stadler, Julia; Narayan, Priyanka; Papademetriou, Jason; Reilly, Luke; Nelson, Matthew P.; Aggarwal, Sanya; Rosen, Leah U.; Kirwan, Peter; Pisupati, Venkat; Coon, Steven L.; Scholz, Sonja W.; Priebe, Theresa; Ottl, Miriam; Dong, Jian; Meijer, Marieke; Janssen, Lara J. M.; Lourenco, Vanessa S.; van der Kant, Rik; Crusius, Dennis; Paquet, Dominik; Raulin, Ana-Caroline; Bu, Guojun; Held, Aaron; Wainger, Brian J.; Gabriele, Rebecca M. C.; Casey, Jackie M.; Wray, Selina; Abu-Bonsrah, Dad; Parish, Clare L.; Beccari, Melinda S.; Cleveland, Don W.; Li, Emmy; Rose, Indigo V. L.; Kampmann, Martin; Aristoy, Carles Calatayud; Verstreken, Patrik; Heinrich, Laurin; Chen, Max Y.; Schule, Birgitt; Dou, Dan; Holzbaur, Erika L. F.; Zanellati, Maria Clara; Basundra, Richa; Deshmukh, Mohanish; Cohen, Sarah; Khanna, Richa; Raman, Malavika; Nevin, Zachary S.; Matia, Madeline; Van Lent, Jonas; Timmerman, Vincent; Conklin, Bruce R.; Chase, Katherine Johnson; Zhang, Ke; Funes, Salome; Bosco, Daryl A.; Erlebach, Lena; Welzer, Marc; Kronenberg-Versteeg, Deborah; Lyu, Guochang; Arenas, Ernest; Coccia, Elena; Sarrafha, Lily; Ahfeldt, Tim; Marioni, John C.; Skarnes, William C.; Cookson, Mark R.; Ward, Michael E.; Merkle, Florian T.

Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors

CIRCULATION

IF38.6

2022-09-06

OAAI

Zhu, Lili; Choudhary, Krishna; Gonzalez-Teran, Barbara; Ang, Yen-Sin; Thomas, Reuben; Stone, Nicole R.; Liu, Lei; Zhou, Ping; Zhu, Chenchen; Ruan, Hongmei; Huang, Yu; Jin, Shibo; Pelonero, Angelo; Koback, Frances; Padmanabhan, Arun; Sadagopan, Nandhini; Hsu, Austin; Costa, Mauro W.; Gifford, Casey A.; van Bemmel, Joke; Huttenhain, Ruth; Vedantham, Vasanth; Conklin, Bruce R.; Black, Brian L.; Bruneau, Benoit G.; Steinmetz, Lars; Krogan, Nevan J.; Pollard, Katherine S.; Srivastava, Deepak

Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies

NATURE COMMUNICATIONS

IF15.7

2021-11-03

OAAI

Fenix, Aidan M.; Miyaoka, Yuichiro; Bertero, Alessandro; Blue, Steven M.; Spindler, Matthew J.; Tan, Kenneth K. B.; Perez-Bermejo, Juan A.; Chan, Amanda H.; Mayerl, Steven J.; Nguyen, Trieu D.; Russell, Caitlin R.; Lizarraga, Paweena P.; Truong, Annie; So, Po-Lin; Kulkarni, Aishwarya; Chetal, Kashish; Sathe, Shashank; Sniadecki, Nathan J.; Yeo, Gene W.; Murry, Charles E.; Conklin, Bruce R.; Salomonis, Nathan

Bioengineered optogenetic model of human neuromuscular junction

BIOMATERIALS

IF12.9

2021-09-01

OAAI

Vila, Olaia F.; Chavez, Miguel; Ma, Stephen P.; Yeager, Keith; Zholudeva, Lyandysha, V; Colon-Mercado, Jennifer M.; Qu, Yihuai; Nash, Trevor R.; Lai, Carmen; Feliciano, Carissa M.; Carter, Matthew; Kamm, Roger D.; Judge, Luke M.; Conklin, Bruce R.; Ward, Michael E.; McDevitt, Todd C.; Vunjak-Novakovic, Gordana

SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-04-21

114

OAAI

Perez-Bermejo, Juan A.; Kang, Serah; Rockwood, Sarah J.; Simoneau, Camille R.; Joy, David A.; Silva, Ana C.; Ramadoss, Gokul N.; Flanigan, Will R.; Fozouni, Parinaz; Li, Huihui; Chen, Pei-Yi; Nakamura, Ken; Whitman, Jeffrey D.; Hanson, Paul J.; McManus, Bruce M.; Ott, Melanie; Conklin, Bruce R.; McDevitt, Todd C.

Rapid, precise quantification of large DNA excisions and inversions by ddPCR

SCIENTIFIC REPORTS

IF3.9

2020-09-10

OAAI

Watry, Hannah L.; Feliciano, Carissa M.; Gjoni, Ketrin; Takahashi, Gou; Miyaoka, Yuichiro; Conklin, Bruce R.; Judge, Luke M.

Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells

CELL REPORTS

IF6.9

2020-06-01

OAAI

Takahashi, Kazutoshi; Jeong, Daeun; Wang, Songnan; Narita, Megumi; Jin, Xuemei; Iwasaki, Mio; Perli, Samuel D.; Conklin, Bruce R.; Yamanaka, Shinya

Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair CDC7的定时抑制增加CRISPR-Cas9介导的模板化修复

NATURE COMMUNICATIONS

IF15.7

2020-04-30

OAAI

Wienert, Beeke; Nguyen, David N.; Guenther, Alexis; Feng, Sharon J.; Locke, Melissa N.; Wyman, Stacia K.; Shin, Jiyung; Kazane, Katelynn R.; Gregory, Georgia L.; Carter, Matthew A. M.; Wright, Francis; Conklin, Bruce R.; Marson, Alex; Richardson, Chris D.; Corn, Jacob E.

研究方向