未登录 Pharmacologic modulation of RNA splicing enhances anti-tumor immunity Thomas, James D.; Lu, Sydney X.; De Neef, Emma; Sabio, Erich; Rousseau, Benoit; Gigoux, Mathieu; Knorr, David A.; Greenbaum, Benjamin; Elhanati, Yuval; Hogg, Simon J.; Chow, Andrew; Ghosh, Arnab; Xie, Abigail; Zamarin, Dmitriy; Cui, Daniel; Erickson, Caroline; Singer, Michael; Cho, Hana; Wang, Eric; Lu, Bin; Durham, Benjamin H.; Shah, Harshal; Chowell, Diego; Gabel, Austin M.; Shen, Yudao; Liu, Jing; Jin, Jian; Rhodes, Matthew C.; Taylor, Richard E.; Molina, Henrik; Wolchok, Jedd D.; Merghoub, Taha; Diaz, Luis A., Jr.; Abdel-Wahab, Omar; Bradley, Robert K. 分享 收藏
Phase Ib study of eprenetapopt (APR-246) in combination with pembrolizumab in patients with advanced or metastatic solid tumors eprenetapopt (APR-246) 联合pembrolizumab治疗晚期或转移性实体瘤的Ib期研究 Park, H.; Shapiro, G., I; Gao, X.; Mahipal, A.; Starr, J.; Furqan, M.; Singh, P.; Ahrorov, A.; Gandhi, L.; Ghosh, A.; Hickman, D.; Gallacher, P. D.; Wennborg, A.; Attar, E. C.; Awad, M. M.; Das, S.; Dumbrava, E. E. 分享 收藏
Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade Ghosh, Arnab; Michels, Judith; Mezzadra, Riccardo; Venkatesh, Divya; Dong, Lauren; Gomez, Ricardo; Samaan, Fadi; Ho, Yu-Jui; Campesato, Luis Felipe; Mangarin, Levi; Fak, John; Suek, Nathan; Holland, Aliya; Liu, Cailian; Abu-Akeel, Mohsen; Bykov, Yonina; Zhong, Hong; Fitzgerald, Kelly; Budhu, Sadna; Chow, Andrew; Zappasodi, Roberta; Panageas, Katherine S.; de Henau, Olivier; Ruscetti, Marcus; Lowe, Scott W.; Merghoub, Taha; Wolchok, Jedd D. 分享 收藏
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine 钙网蛋白突变体骨髓增生性肿瘤诱导mhc-i偏斜，这可以通过优化的肽癌症疫苗来克服 Gigoux, Mathieu; Holmstrom, Morten O.; Zappasodi, Roberta; Park, Joseph J.; Pourpe, Stephane; Bozkus, Cansu Cimen; Mangarin, Levi M. B.; Redmond, David; Verma, Svena; Schad, Sara; George, Mariam M.; Venkatesh, Divya; Ghosh, Arnab; Hoyos, David; Molvi, Zaki; Kamaz, Baransel; Marneth, Anna E.; Duke, William; Leventhal, Matthew J.; Jan, Max; Ho, Vincent T.; Hobbs, Gabriela S.; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob H.; Lisle, Thomas L.; Met, Ozcan; Wilkinson, Patrick; Greenbaum, Benjamin; Sepulveda, Manuel A.; Chan, Timothy; Rampal, Raajit; Andersen, Mads H.; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd D.; Mullally, Ann; Merghoub, Taha 分享 收藏
Generation and characterization of a novel hematopoietic progenitor cell line with DC differentiation potential (vol 20, pg 870, 2006) Rathinam, C.; Sauer, M.; Ghosh, A.; Rudolph, C.; Hegazy, A.; Schlegelberger, B.; Welte, K.; Klein, C. 分享 收藏
MHC-I SKEWING IN MUTANT CALRETICULIN-POSITIVE MYELOPROLIFERATIVE NEOPLASMS IS COUNTERED BY HETEROCLITIC PEPTIDE CANCER VACCINATION Gigoux, Mathieu; Zappasodi, Roberta; Park, Joseph; Pourpe, Stephane; Ghosh, Arnab; Bozkus, Cansu Cimen; Mangarin, Levi; Redmond, David; Verma, Svena; Schad, Sara; Duke, William; Jan, Max; Leventhal, Matthew; Ho, Vincent; Hobbs, Gabriela; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob; Andersen, Mads; Holmstrom, Morten; Chan, Timothy; Rampal, Raajit; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd; Mullally, Ann; Merghoub, Taha 分享 收藏
CTLA-4 blockade drives loss of regulatory T cell functional stability in glycolysis defective tumors Zappasodi, Roberta; Serganova, Inna; Cohen, Ivan; Maeda, Masatomo; Shindo, Masahiro; Senbabaoglu, Yasin; Leftin, Avigdor; Maniyar, Rachana; Verma, Svena; Lubin, Matthew; Ko, Myat Kyaw; Mane, Mayuresh M.; Ghosh, Arnab; Ackerstaff, Ellen; Koutcher, Jason A.; Ho, Ping-Chih; Delgoffe, Greg M.; Blasberg, Ronald; Wolchok, Jedd D.; Merghoub, Taha 分享 收藏
Chimeric antigen receptor-induced BCL11B suppression propagates NK-like cell development Maluski, Marcel; Ghosh, Arnab; Herbst, Jessica; Scholl, Vanessa; Baumann, Rolf; Huehn, Jochen; Geffers, Robert; Meyer, Johann; Maul, Holger; Eiz-Vesper, Britta; Krueger, Andreas; Schambach, Axel; Van den Brink, Marcel R. M.; Sauer, Martin G. 分享 收藏
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Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity 供体CD19 CAR T细胞发挥有效的移植物抗淋巴瘤活性，移植物抗宿主活性降低 Ghosh, Arnab; Smith, Melody; James, Scott E.; Davila, Marco L.; Velardi, Enrico; Argyropoulos, Kimon V.; Gunset, Gertrude; Perna, Fabiana; Kreines, Fabiana M.; Levy, Emily R.; Lieberman, Sophie; Jay, Hillary V.; Tuckett, Andrea Z.; Zakrzewski, Johannes L.; Tan, Lisa; Young, Lauren F.; Takvorian, Kate; Dudakov, Jarrod A.; Jenq, Robert R.; Hanash, Alan M.; Motta, Ana Carolina F.; Murphy, George F.; Liu, Chen; Schietinger, Andrea; Sadelain, Michel; van den Brink, Marcel R. M. 分享 收藏
Generation of Genetically Engineered Precursor T-Cells From Human Umbilical Cord Blood Using an Optimized Alpharetroviral Vector Platform Huebner, Juwita; Hoseini, Shahabuddin S.; Suerth, Julia D.; Hoffmann, Dirk; Maluski, Marcel; Herbst, Jessica; Maul, Holger; Ghosh, Arnab; Eiz-Vesper, Britta; Yuan, Qinggong; Ott, Michael; Heuser, Michael; Schambach, Axel; Sauer, Martin G. 分享 收藏
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PLZF Confers Effector Functions to Donor T Cells That Preserve Graft-versus-Tumor Effects while Attenuating GVHD Ghosh, Arnab; Holland, Amanda M.; Dogan, Yildirim; Yim, Nury L.; Rao, Uttam K.; Young, Lauren F.; West, Mallory L.; Singer, Natalie V.; Lee, Hae; Na, Il-Kang; Tsai, Jennifer J.; Jenq, Robert R.; Penack, Olaf; Hanash, Alan M.; Lezcano, Cecilia; Murphy, George F.; Liu, Chen; Sadelain, Michel; Sauer, Martin G.; Sant'Angelo, Derek; van den Brink, Marcel R. M. 分享 收藏
Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity 过继转移的TRAIL T细胞抑制GVHD并增强抗肿瘤活性 Ghosh, Arnab; Dogan, Yildirim; Moroz, Maxim; Holland, Amanda M.; Yim, Nury L.; Rao, Uttam K.; Young, Lauren F.; Tannenbaum, Daniel; Masih, Durva; Velardi, Enrico; Tsai, Jennifer J.; Jenq, Robert R.; Penack, Olaf; Hanash, Alan M.; Smith, Odette M.; Piersanti, Kelly; Lezcano, Cecilia; Murphy, George F.; Liu, Chen; Palomba, M. Lia; Sauer, Martin G.; Sadelain, Michel; Ponomarev, Vladimir; van den Brink, Marcel R. M. 分享 收藏
Nrf2 regulates haematopoietic stem cell function Nrf2调控造血干细胞功能 Tsai, Jennifer J.; Dudakov, Jarrod A.; Takahashi, Koichi; Shieh, Jae-Hung; Velardi, Enrico; Holland, Amanda M.; Singer, Natalie V.; West, Mallory L.; Smith, Odette M.; Young, Lauren F.; Shono, Yusuke; Ghosh, Arnab; Hanash, Alan M.; Tran, Hien T.; Moore, Malcolm A. S.; van den Brink, Marcel R. M. 分享 收藏
Generation and characterization of a novel hematopoietic progenitor cell line with DC differentiation potential (vol 20, pg 870, 2006) Rathinam, C.; Sauer, M.; Ghosh, A.; Rudolph, C.; Hegazy, A.; Schlegelberger, B.; Welte, K.; Klein, C. 分享 收藏
Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease Interleukin-22保护肠道干细胞免受免疫介导的组织损伤并调节对移植物抗宿主病的敏感性 Hanash, Alan M.; Dudakov, Jarrod A.; Hua, Guoqiang; O'Connor, Margaret H.; Young, Lauren F.; Singer, Natalie V.; West, Mallory L.; Jenq, Robert R.; Holland, Amanda M.; Kappel, Lucy W.; Ghosh, Arnab; Tsai, Jennifer J.; Rao, Uttam K.; Yim, Nury L.; Smith, Odette M.; Velardi, Enrico; Hawryluk, Elena B.; Murphy, George F.; Liu, Chen; Fouser, Lynette A.; Kolesnick, Richard; Blazar, Bruce R.; van den Brink, Marcel R. M. 分享 收藏
Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation 微生物群对异基因骨髓移植后肠道炎症的调控 Jenq, Robert R.; Ubeda, Carles; Taur, Ying; Menezes, Clarissa C.; Khanin, Raya; Dudakov, Jarrod A.; Liu, Chen; West, Mallory L.; Singer, Natalie V.; Equinda, Michele J.; Gobourne, Asia; Lipuma, Lauren; Young, Lauren F.; Smith, Odette M.; Ghosh, Arnab; Hanash, Alan M.; Goldberg, Jenna D.; Aoyama, Kazutoshi; Blazar, Bruce R.; Pamer, Eric G.; van den Brink, Marcel R. M. 分享 收藏
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