Aykut Üren - Publications, H-index & Citations

Aykut Üren

Georgetown University Medical Center

45H指数

305论文数

7.0K被引数

收录论文 116

发表时间

PAX3::FOXO1-Targeting PROTAC Induces Myogenic Differentiation of Fusion-Positive Rhabdomyosarcoma Cells PAX3::FOXO1靶向PROTAC诱导融合阳性横纹肌肉瘤细胞的肌源性分化

Cancers

IF4.4

2026-07-24

OAAI

Nikola Knoll; Kayra Somay; Purushottam B. Tiwari; Emre Deniz; Jeffrey S. S. K. Formen; Isabel Frye; Eryn Nelson; Christian Wolf; Jeffrey A. Toretsky; Aykut Üren

Identifying potential binding sites for complex formation between Tyrosyl-DNA phosphodiesterase 1 and poly [ADP-ribose] polymerase 1 鉴定酪氨酰-DNA磷酸二酯酶1与聚[ADP-核糖]聚合酶1之间复合物形成的潜在结合位点

phys. chem. chem. phys.

IF0

2026-05-19

OAAI

Sophia Wang; Aykut Üren; Purushottam Tiwari

Mechanisms and Design Principles of Proteolysis-Targeting Chimeras and Their Emerging Applications 蛋白酶体靶向嵌合体的机制与设计原则及其新兴应用

ACS Pharmacology & Translational Science

IF3.7

2026-03-16

OAAI

Nikola Knoll; Nouri Neamati; Aykut Üren

BPS2026 – RNA-binding properties of ezrin in its closed conformation BPS2026——ezrin在关闭构象下的RNA结合特性

Biophysical Journal

IF3.1

2026-02-19

PREAI

Prakriti Tiwari; Anup Tiwari; Emre Deniz; Aykut Üren

A Novel FLI1 Monoclonal Antibody Which Recognizes EWS::FLI1 with High Affinity Is Useful for Detecting Ewing Sarcoma 一种新型FLI1单克隆抗体，能够高亲和力识别EWS::FLI1，可用于检测尤文氏肉瘤

Antibodies 2025, Vol. 14, Page 97

IF2.7

2025-11-10

OAAI

Saravana P. Selvanathan; Olivia O. Lansinger; David V. Allegakoen; Emma J. W. McGuire; Ashley R. Gaffey; Jeff R. Petro; Purushottam B. Tiwari; Quinn Tufiño; Aykut Üren; Jeffrey A. Toretsky

Investigating SMR Peptide Interactions with Breast Cancer-Associated Proteins 研究SMR肽与乳腺癌相关蛋白的相互作用

International Journal of Molecular Sciences 2025, Vol. 26, Page 8848

IF4.9

2025-09-21

OAAI

Ming-Bo Huang; Purushottam B. Tiwari; Aykut Üren; Martin N. Shelton; Dara Brena; Jennifer Y. Wu; Mahfuz B. Khan; Michael D. Powell; Jonathan K. Stiles; Erica L. Johnson; Fengxia Yan; Lily Yang; Vincent C. Bond

ROME, a novel membrane protein in vertebrates, enhances metastatic phenotype of Ewing sarcoma cells

CANCER RESEARCH

IF16.6

2024-09-05

PREAI

Molotkova, Anna; Deniz, Emre; Swift, Matthew; Glasgow, Eric; Toretsky, Rey; Uren, Aykut

Oncological and Urological Outcomes After Total Pelvic Exenteration - Our 10-Year Experience

BRITISH JOURNAL OF SURGERY

IF8.7

2024-07-03

PREAI

Rajamoorthy, S., I; Uren, A.; Rajan, K.; Mubarak, M.; Dixon, C.; Jeavons, F.; Bose, P.; Lucas, M.; Featherstone, J.; Gill, N.; Swamy, G. V. Kanda

Small molecule inhibitors of the PAX3::FOXO1 fusion protein in rhabdomyosarcoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Shaw, Taryn; Nakazawa, Kay; Tiwari, Purushottam; Nelson, Eryn; Formen, Jeffrey; Wolf, Christian; Toretsky, Jeffrey; Uren, Aykut

In vivo CRISPR/Cas9 transcriptional activation screen leads to discovery of INAFM2, a novel driver of metastasis

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Molotkova, Anna; Deniz, Emre; Swift, Matthew; Glasgow, Eric; Toretsky, Jeffrey; Uren, Aykut

Design, synthesis and biological evaluation of Nucleosidic CD99 inhibitors that selectively reduce Ewing sarcoma viability

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-05-01

OAAI

Balaraman, Kaluvu; Deniz, Emre; Nelson, Eryn; Pilicer, Samantha L.; Atasoy, Sezen; Molotkova, Anna; Sevim, Handan; Tiwari, Purushottam B.; Uren, Aykut; Wolf, Christian

Lymphocyte antigen 6K signaling to aurora kinase promotes advancement of the cell cycle and the growth of cancer cells, which is inhibited by LY6K-NSC243928 interaction 淋巴细胞抗原6k信号传导到极光激酶促进细胞周期的进展和癌细胞的生长，这被LY6K-NSC243928相互作用抑制

CANCER LETTERS

IF10.1

2023-04-01

OAAI

Selvanesan, Benson Chellakkan; Varghese, Sheelu; Andrys-Olek, Justyna; Arriaza, Ricardo Hernandez; Prakash, Rahul; Tiwari, Purushottam Babu; Hupalo, Daniel; Gusev, Yuriy; Patel, Megha Nitin; Contente, Sara; Sanda, Miloslav; Uren, Aykut; Wilkerson, Matthew D.; Dalgard, Clifton Lee; Shimizu, Linda S.; Chruszcz, Maksymilian; Borowski, Tomasz; Upadhyay, Geeta

Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3-and c-Jun n-terminal kinase-dependent mechanism

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

100

OAAI

Endo, Yoshimi; Beauchamp, Elspeth; Woods, David; Taylor, William G.; Toretsky, Jeffrey A.; Uren, Aykut; Rubin, Jeffrey S.

Ezrin Binds to DEAD-Box RNA Helicase DDX3 and Regulates Its Function and Protein Level

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Celik, Haydar; Sajwan, Kamal P.; Selvanathan, Saravana P.; Marsh, Benjamin J.; Pai, Amrita V.; Kont, Yasemin Saygideger; Han, Jenny; Minas, Tsion Z.; Rahim, Said; Erkizan, Hayriye Verda; Toretsky, Jeffrey A.; Ueren, Aykut

Comprehensive profiling of mRNA splicing indicates that GC content signals altered cassette exon inclusion in Ewing sarcoma

NAR CANCER

IF3.2

2022-01-14

OAAI

Graham, Garrett T.; Selvanathan, Saravana P.; Zoellner, Stefan K.; Stahl, Emily; Shlien, Adam; Caplen, Natasha J.; Uren, Aykut; Toretsky, Jeffrey A.

Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression

CANCER RESEARCH

IF16.6

2021-06-28

OAAI

Pallmann, Nora; Deng, Ke; Livgard, Marte; Tesikova, Martina; Jin, Yixin; Frengen, Nicolai Sebastian; Kahraman, Nermin; Mokhlis, Hamada M.; Ozpolat, Bulent; Kildal, Wanja; Danielsen, Havard Emil; Fazli, Ladan; Rennie, Paul S.; Banerjee, Partha P.; Uren, Aykut; Jin, Yang; Kuzu, Omer F.; Saatcioglu, Fahri

Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development (vol 15, pg 623, 2020)

CHEMMEDCHEM

IF3.4

2021-06-18

OAAI

Tiwari, Purushottam B.; Chapagain, Prem P.; Seddek, Ahmed; Annamalai, Thirunavukkarasu; uren, Aykut; Tse-Dinh, Yuk-Ching

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells

ONCOGENESIS

IF6.4

2021-01-08

OAAI

Bierbaumer, Lisa; Katschnig, Anna M.; Radic-Sarikas, Branka; Kauer, Maximilian O.; Petro, Jeffrey A.; Hoegler, Sandra; Gurnhofer, Elisabeth; Pedot, Gloria; Schafer, Beat W.; Schwentner, Raphaela; Muehlbacher, Karin; Kromp, Florian; Aryee, Dave N. T.; Kenner, Lukas; Uren, Aykut; Kovar, Heinrich

Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development DNA和细菌拓扑异构酶的共价复合物: 在抗菌药物开发中的意义

CHEMMEDCHEM

IF3.4

2020-03-18

OAAI

Tiwari, Purushottam B.; Chapagain, Prem P.; Seddek, Ahmed; Annamalai, Thirunavukkarasu; Uren, Aykut; Tse-Dinh, Yuk-Ching

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition 靶向蛋白磷酸酶-1非催化RVxF位点的小分子埃博拉病毒抑制

FRONTIERS IN MICROBIOLOGY

IF4.5

2019-09-13

OAAI

Lin, Xionghao; Ammosova, Tatiana; Choy, Meng S.; Pietzsch, Colette A.; Ivanov, Andrey; Ahmad, Asrar; Saygideger, Yasemin; Kumari, Namita; Kovalskyy, Dmytro; Uren, Aykut; Peti, Wolfgang; Bukreyev, Alexander; Nekhai, Sergei

研究方向