Christine L. Chaffer - Publications, H-index & Citations

Christine L. Chaffer

EMBL Australia

23H指数

85论文数

1.4W被引数

收录论文 28

发表时间

Androgen receptor localisation and protein interactions provide insight into steroid mediated metabolic shifts in endocrine resistant breast cancer 雄激素受体定位和蛋白质相互作用为内分泌抵抗性乳腺癌中类固醇介导的代谢转变提供了见解。

npj Breast Cancer

IF7.6

2026-03-17

OAAI

Rachel Bleach; Emir Bozkurt; Jingqi Xin; Katherine M. Sheehan; Sally Shirran; Stephanie Agbana; Mihaela Ola; Leonie Young; Nicole S. Spoelstra; Jennifer K. Richer; Ana Cristina Vargas; Leonard D. Goldstein; Heloisa H. Milloli; Christine L. Chaffer; Michael W O’Reilly; Jochen HM Prehn; Marie McIlroy

Isoform-specific single-cell perturb-seq reveals distinct functions of alternative promoters in drug response

Nucleic Acids Research

IF13.1

2026-02-27

PREAI

King, Helen E.; O'Connell, Savannah; Kavanagh, Daisy; Mason, Sofia; McCool, Cerys; Fernandez-Chamorro, Javier; Chaffer, Christine L.; Clark, Susan J.; Vieira, Helaine Graziele S.; Sterne-Weiler, Timothy; Weatheritt, Robert J.

Epithelial-mesenchymal cell state heterogeneity predetermines differential phospho-signaling responses to EGF stimulation 上皮-间充质细胞状态异质性预决定了EGF刺激下不同的磷酸化信号反应

Molecular Biology of the Cell

IF2.7

2026-01-01

PREAI

Kohane, Felix, V; Johnstone, Chantelle; Neumann, Daniel P.; Gunawan, Ihuan; Huang, Tim; Vafaee, Fatemeh; Chaffer, Christine L.; Lock, John G.

Capillary constrictions prime cancer cell tumorigenicity through PIEZO1 毛细血管收缩通过PIEZO1促进癌细胞成瘤性

Nature Communications

IF15.7

2025-09-01

OAAI

Giulia Silvani; Chantal Kopecky; Sara Romanazzo; Vanina Rodríguez; Ayan Das; Elvis Pandzic; John G. Lock; Christine L. Chaffer; Kate Poole; Kristopher A. Kilian

EXPLORING THE ROLE OF ANDROGEN RECEPTOR SIGNALING IN GLIOBLASTOMA IN AN ORTHOTOPIC ANIMAL MODEL

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Mason, Sofia R. E.; Chung, Sylvia; Satgunaseelan, Laveniya; Mccool, Cerys; Juan, Beatriz Perez-San; Gupta, Shabarni; Zaman, Ashraf; Day, Bryan W.; Dear, Rachel; Sim, Hao-Wen; Holst, Jeff; Chaffer, Christine L.

Chemotherapy and the Extra-Tumor Immune Microenvironment: EXTRA-TIME

CANCER DISCOVERY

IF33.3

2024-04-04

OAAI

Phan, Tri Giang; Weilbaecher, Katherine N.; Aft, Rebecca; Croucher, Peter I.; Chaffer, Christine L.

Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer 在三阴性乳腺癌中使用CRISPR/dCas9平台的间充质上皮状态的合成表观遗传重编程

ADVANCED SCIENCE

IF14.1

2023-05-22

OAAI

Waryah, Charlene; Cursons, Joseph; Foroutan, Momeneh; Pflueger, Christian; Wang, Edina; Molania, Ramyar; Sorolla, Anabel; Wallis, Christopher; Moses, Colette; Glas, Irina; Magalhaes, Leandro; Thompson, Erik W.; Fearnley, Liam G.; Chaffer, Christine L.; Davis, Melissa; Papenfuss, Anthony T.; Redfern, Andrew; Lister, Ryan; Esteller, Manel; Blancafort, Pilar

4CAST: A Phase 1b dose exploration and dose expansion, open-label study evaluating the safety and efficacy of INO-464 in combination with Chemotherapy in patients with metASTatic breast cancer

CANCER RESEARCH

IF16.6

2023-03-01

PREAI

Dear, Rachel F.; Batty, Kathleen; Perez, Beatriz; Chaffer, Christine

Single-cell multi-modal GAN reveals spatial patterns in single-cell data from triple-negative breast cancer

PATTERNS

IF7.4

2022-09-01

OAAI

Amodio, Matthew; Youlten, Scott E.; Venkat, Aarthi; San Juan, Beatriz P.; Chaffer, Christine L.; Krishnaswamy, Smita

Mapping Phenotypic Plasticity upon the Cancer Cell State Landscape Using Manifold Learning 使用流形学习在癌细胞状态景观上映射表型可塑性

CANCER DISCOVERY

IF33.3

2022-06-23

OAAI

Burkhardt, Daniel B.; San Juan, Beatriz P.; Lock, John G.; Krishnaswamy, Smita; Chaffer, Christine L.

CD44 Orchestrates Metastatic Teamwork

DEVELOPMENTAL CELL

IF8.7

2018-12-01

OAAI

Chaffer, Christine L.; Goetz, Jacky G.

IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization

NATURE CELL BIOLOGY

IF19.1

2018-08-27

125

OAAI

Castano, Zafira; San Juan, Beatriz P.; Spiegel, Asaf; Pant, Ayush; DeCristo, Molly J.; Laszewski, Tyler; Ubellacker, Jessalyn M.; Janssen, Susanne R.; Dongre, Anushka; Reinhardt, Ferenc; Henderson, Ayana; del Rio, Ana Garcia; Gifford, Ann M.; Herbert, Zachary T.; Hutchinson, John N.; Weinberg, Robert A.; Chaffer, Christine L.; McAllister, Sandra S.

An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

ELIFE

IF0

2018-07-30

OAAI

Li, Ji; Choi, Peter S.; Chaffer, Christine L.; Labella, Katherine; Hwang, Justin H.; Giacomelli, Andrew O.; Kim, Jong Wook; Ilic, Nina; Doench, John G.; Ly, Seav Huong; Dai, Chao; Hagel, Kimberly; Hong, Andrew L.; Gjoerup, Ole; Goel, Shom; Ge, Jennifer Y.; Root, David E.; Zhao, Jean J.; Brooks, Angela N.; Weinberg, Robert A.; Hahn, William C.

A genome-scale ORF screen reveals an alternative splicing program that regulates mesenchymal and stem-like cell states in breast cancer

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Li, Ji; Choi, Peter; Chaffer, Christine; Labella, Katherine; Kim, Jong Wook; Doench, John; Dai, Chao; Giacomelli, Andrew; Ly, Seav Huong; Hwang, Justin; Hong, Andrew; Ilic, Nina; Gjoerup, Ole; Meyerson, Matthew; Brooks, Angela; Weinberg, Robert; Hahn, William

Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-03-07

253

OAAI

Bierie, Brian; Pierce, Sarah E.; Kroeger, Cornelia; Stover, Daniel G.; Pattabiraman, Diwakar R.; Thiru, Prathapan; Donaher, Joana Liu; Reinhardt, Ferenc; Chaffer, Christine L.; Keckesova, Zuzana; Weinberg, Robert A.

EMT, cell plasticity and metastasis

CANCER AND METASTASIS REVIEWS

IF8.7

2016-11-22

706

PREAI

Chaffer, Christine L.; San Juan, Beatriz P.; Lim, Elgene; Weinberg, Robert A.

Understanding the systemic interactions between primary tumors and disseminated tumor initiating cells

CANCER RESEARCH

IF16.6

2016-07-28

PREAI

Castano, Zafira; Chaffer, Christine L.; Spiegel, Asaf; Pant, Ayush; Richardson, Andrea L.; Reinhardt, Ferenc; Marsh, Timothy; Janssen, Susanne; Gifford, Ann M.; Weinberg, Robert A.; McAllister, Sandra S.

How Does Multistep Tumorigenesis Really Proceed?

CANCER DISCOVERY

IF33.3

2015-01-11

144

OAAI

Chaffer, Christine L.; Weinberg, Robert A.

Poised with purpose Cell plasticity enhances tumorigenicity

CELL CYCLE

IF3.4

2014-10-28

OAAI