未登录 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication 载脂蛋白E基因簇蛋白的保护性等位基因通过脂滴介导的神经元-胶质细胞通讯调节神经元兴奋性。 Zhao, Xiaojie; Li, Yan; Zhang, Siwei; Sudwarts, Ari; Zhang, Hanwen; Kozlova, Alena; Moulton, Matthew J.; Goodman, Lindsey D.; Pang, Zhiping P.; Sanders, Alan R.; Bellen, Hugo J.; Thinakaran, Gopal; Duan, Jubao 分享 收藏
分享 收藏
分享 收藏
Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts (vol 11, 59, 2016) De Rossi, Pierre; Buggia-Prevot, Virginie; Clayton, Benjamin L. L.; Vasquez, Jared B.; van Sanford, Carson; Andrew, Robert J.; Lesnick, Ruben; Botte, Alexandra; Deyts, Carole; Salem, Someya; Rao, Eshaan; Rice, Richard C.; Parent, Angele; Kar, Satyabrata; Popko, Brian; Pytel, Peter; Estus, Steven; Thinakaran, Gopal 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells U18666A对内体-溶酶体胆固醇的隔离差异调节正常和过表达淀粉样前体蛋白 (APP) 的细胞代谢 Chung, J.; Phukan, G.; Vergote, D.; Mohamed, A.; Maulik, M.; Stahn, M.; Andrew, R. J.; Thinakaran, G.; de Chaves, E. Posse; Kar, S. 分享 收藏
Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis Ulku, Irem; Liebsch, Filip; Akerman, S. Can; Schulz, Jana F.; Kulic, Luka; Hock, Christoph; Pietrzik, Claus; Di Spiezio, Alessandro; Thinakaran, Gopal; Saftig, Paul; Multhaup, Gerhard 分享 收藏
Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model Ponnusamy, Moorthi; Wang, Shuai; Yuksel, Melike; Hansen, Mitchell T.; Blazier, Danielle M.; McMillan, Joseph D.; Zhang, Xiaolin; Dammer, Eric B.; Collier, Lisa; Thinakaran, Gopal 分享 收藏
BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia Sudwarts, Ari; Ramesha, Supriya; Gao, Tianwen; Ponnusamy, Moorthi; Wang, Shuai; Hansen, Mitchell; Kozlova, Alena; Bitarafan, Sara; Kumar, Prateek; Beaulieu-Abdelahad, David; Zhang, Xiaolin; Collier, Lisa; Szekeres, Charles; Wood, Levi B.; Duan, Jubao; Thinakaran, Gopal; Rangaraju, Srikant 分享 收藏
分享 收藏
Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention Rynearson, Kevin D.; Ponnusamy, Moorthi; Prikhodko, Olga; Xie, Yuhuan; Zhang, Can; Nguyen, Phuong; Hug, Brenda; Sawa, Mariko; Becker, Ann; Spencer, Brian; Florio, Jazmin; Mante, Michael; Salehi, Bahar; Arias, Carlos; Galasko, Douglas; Head, Brian P.; Johnson, Graham; Lin, Jiunn H.; Duddy, Steven K.; Rissman, Robert A.; Mobley, William C.; Thinakaran, Gopal; Tanzi, Rudolph E.; Wagner, Steven L. 分享 收藏
分享 收藏
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation De Rossi, Pierre; Nomura, Toshihiro; Andrew, Robert J.; Masse, Nicolas Y.; Sampathkumar, Vandana; Musial, Timothy F.; Sudwarts, Ari; Recupero, Aleksandra J.; Le Metayer, Thomas; Hansen, Mitchell T.; Shim, Ha-Na; Krause, Sofia V.; Freedman, David J.; Bindokas, Vytas P.; Kasthuri, Narayanan; Nicholson, Daniel A.; Contractor, Anis; Thinakaran, Gopal 分享 收藏
APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model Deyts, Carole; Clutter, Mary; Pierce, Nicholas; Chakrabarty, Paramita; Ladd, Thomas B.; Goddi, Anna; Rosario, Awilda M.; Cruz, Pedro; Vetrivel, Kulandaivelu; Wagner, Steven L.; Thinakaran, Gopal; Golde, Todd E.; Parent, Angele T. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
