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R

Rachael Natrajan

The Institute of Cancer Research
H指数:66
被引数:1.5万

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The anion channel GPR89 is a tumor-specific dependency in breast cancer

GPR89阴离子通道是乳腺癌的肿瘤特异性依赖

Nature Communications
IF15.7
2026-08-240
OA
Riccardo Ferro; Alexandra Carroll; Ana M. Mendes-Pereira; Virinder Reen; George Vlachogiannis; Rebeca Uceda-Castro; Dragomir Krastev; Valeria Amodeo; Stephen Pettitt; Nadja D’Uonno; Ioanna Mavrommati; Blanca Navarro; Luke Hitchen; Jennifer Trendell; Ana Stojiljkovic; Cynthia Prince; Narinder Janghra; Ioannis Roxanis; Patrycja Gazinska; Daniel Larcombe-Young; Rebecca Marlow; Stefano Annunziato; Jos Jonkers; Tejashree Rajaram Kanitkar; Amadeus Xu; Nirmesh Patel; Nalan Liv; John Alexander; Jelmar Quist; Mercedes Pardo; Theodoros I. Roumeliotis; Jyoti S. Choudhary; Daniel Weekes; Pierfrancesco Marra; Joanna I. Loizou; Rachael Natrajan; Anita Grigoriadis; Mallur Srivatsan Madhusudhan; Syed Haider; Christopher J. Lord; Andrew Tutt
Co-occurrence of transcriptionally distinct persister cell states underpins neoadjuvant therapy resistance in triple‑negative breast cancer

转录异质性持久细胞状态的共发生是三阴性乳腺癌新辅助治疗耐药的基础

Genome Medicine
IF11.2
2026-04-090
OA
Yu Zhang; Fatemeh Ahmadi Moughari; Ioanna Mavrommati; Nora J. Doleschall; Kate Moore; Gareth Muirhead; Ram Rajaram Srinivasan; Ping Gong; Jonathan T. Lei; Amy Fleming; Hwei Minn Khoo; Naomi Guppy; Gabrielle Elshtein; Mohammed Inayatullah; Vijay K. Tiwari; Lacey E. Dobrolecki; Michael T. Lewis; Syed Haider; Rachael Natrajan
Clinical challenges and proposed solutions for patients with invasive lobular breast cancer

浸润性小叶乳腺癌患者的临床挑战和建议的解决方案

Annals of Oncology
IF65.4
2025-07-210
OAAI
K. Van Baelen; E. Sawyer; J. Van Cauwenberge; P. Aftimos; M.F. Covington; M. Maetens; G. Zels; C. Brisken; L. Djerroudi; R. Dresen; A. Fitzpatrick; R.L. Flaherty; G. Floris; S. Freeney; A.B. Hanker; D. Honey; C.M. Isacke; R.C. Jankowitz; R. Jeselsohn; T. Koorman; C. Kuhl; S. Linn; C.J. Lord; C. Malhaire; J. Mouabbi; R. Mukhtar; G. Nader-Marta; R. Natrajan; P. Neven; S. Oesterreich; J.L. Sandoval; S.J. Schnitt; E. Senkus; C. Turner; V. Vandecaveye; H. Wildiers; A. Vincent-Salomon; P.W.B. Derksen; C. Desmedt
SF3B1 hotspot mutations confer sensitivity to PARP inhibition through a defective replication stress response
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-12-010
PRE
Bland, Philip; Saville, Harry; Wai, Patty T.; Curnow, Lucinda; Nieminuszczy, Jadwiga; Ravindran, Nivedita; Barker, Holly E.; Wright, James; Yu, Lu; Mavrommati, Ioanna; Peck, Barrie; Gazinska, Patrycja; Pemberton, Helen N.; Gulati, Aditi; Guppy, Naomi; Roxanis, Ioannis; Pratt, Guy; Oldreive, Ceri; Stankovic, Tatjana; Barlow, Samantha; Kalirai, Helen; Coupland, Sarah E.; Broderick, Ronan; Alsafadi, Samar; Houy, Alexandre; Stern, Marc-Henri; Pettit, Stephen; Choudhary, Jyoti S.; Haider, Syed; Niedzwiedz, Wojciech; Lord, Christopher J.; Natrajan, Rachael
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response
NATURE GENETICS
IF31.8
2023-07-3118
OAAI
Bland, Philip; Saville, Harry; Wai, Patty T.; Curnow, Lucinda; Muirhead, Gareth; Nieminuszczy, Jadwiga; Ravindran, Nivedita; John, Marie Beatrix; Hedayat, Somaieh; Barker, Holly E.; Wright, James; Yu, Lu; Mavrommati, Ioanna; Read, Abigail; Peck, Barrie; Allen, Mark; Gazinska, Patrycja; Pemberton, Helen N.; Gulati, Aditi; Nash, Sarah; Noor, Farzana; Guppy, Naomi; Roxanis, Ioannis; Pratt, Guy; Oldreive, Ceri; Stankovic, Tatjana; Barlow, Samantha; Kalirai, Helen; Coupland, Sarah E.; Broderick, Ronan; Alsafadi, Samar; Houy, Alexandre; Stern, Marc-Henri; Pettit, Stephen; Choudhary, Jyoti S.; Haider, Syed; Niedzwiedz, Wojciech; Lord, Christopher J.; Natrajan, Rachael
Mutations in the RNA Splicing Factor SF3B1 drive endocrine therapy resistance and confer a targetable replication stress response defect through PARP inhibition
CANCER RESEARCH
IF16.6
2023-03-010
PRE
Bland, Phil; Saville, Harry; Read, Abigail; Wai, Patty; Muirhead, Gareth; Curnow, Lucinda; Nieminuszczy, Jadwiga; Ravindran, Nivedita; John, Marie; Hedayat, Somaieh; Barker, Holly; Wright, James; Yu, Lu; Mavrommati, Ioanna; Peck, Barrie; Allen, Mark; Gazinska, Patrycja; Pemberton, Helen; Gulati, Aditi; Nash, Sarah; Noor, Farzana; Guppy, Naomi; Roxanis, Ioannis; Barlow, Samantha; Kalirai, Helen; Coupland, Sarah; Broderick, Ronan; Alsafadi, Samar; Houy, Alexandre; Stern, Marc-Henri; Pettit, Stephen; Choudhary, Jyoti; Haider, Syed; Niedzwiedz, Wojciech; Lord, Christopher; Natrajan, Rachael
3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer
CANCER RESEARCH
IF16.6
2021-02-1510
OA
Peck, Barrie; Bland, Philip; Mavrommati, Ioanna; Muirhead, Gareth; Cottom, Hannah; Wai, Patty T.; Maguire, Sarah L.; Barker, Holly E.; Morrison, Eamonn; Kriplani, Divya; Yu, Lu; Gibson, Amy; Falgari, Giulia; Brennan, Keith; Farnie, Gillian; Buus, Richard; Marlow, Rebecca; Novo, Daniela; Knight, Eleanor; Guppy, Naomi; Kolarevic, Daniela; Susnjar, Snezana; Milijic, Natasa Medic; Naidoo, Kalnisha; Gazinska, Patrycja; Roxanis, Ioannis; Pancholi, Sunil; Martin, Lesley-Ann; Holgersen, Erle M.; Cheang, Maggie C. U.; Noor, Farzana; Postel-Vinay, Sophie; Quinn, Gerard; McDade, Simon; Krasny, Lukas; Huang, Paul; Daley, Frances; Wallberg, Fredrik; Choudhary, Jyoti S.; Haider, Syed; Tutt, Andrew N.; Natrajan, Rachael

研究方向

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J
Jorge S. Reis‐Filho
H 指数:153论文数:1,521被引数:9.5万
A
Alan Mackay
H 指数:73论文数:492被引数:1.9万
C
Christopher J. Lord
H 指数:98论文数:710被引数:4.5万
B
Britta Weigelt
H 指数:97论文数:1,083被引数:3.5万
A
Alan Ashworth
H 指数:121论文数:1,006被引数:6.7万
M
Maryou B. Lambros
H 指数:43论文数:120被引数:6,522
K
Kerry Fenwick
H 指数:50论文数:242被引数:8,940
F
Felipe C. Geyer
H 指数:45论文数:181被引数:7,934
A
Alan Ashworth
H 指数:89论文数:422被引数:3.2万
A
Anne Vincent‐Salomon
H 指数:110论文数:1,076被引数:6.5万