Pádraig D’Arcy - Publications, H-index & Citations

Pádraig D’Arcy

Linkoping University

30H指数

100论文数

3.5K被引数

收录论文 50

发表时间

Loss of DNA methylation is not associated with venetoclax–hypomethylating agents synergy in acute myeloid leukaemia cells DNA甲基化丢失与维奈克拉–低甲基化剂协同作用在急性髓系白血病细胞中无关联

British Journal of Haematology

IF3.8

2026-08-21

OAAI

Aida Selimović-Pašić; Lisa Haglund; Maike Bensberg; Júlia Goldmann; Padraig D'arcy; Sandra Hellberg; Colm E. Nestor

Dynamic networks connect the USP14 active site region with the proteasome interaction surface 动态网络连接了USP14活性位点区域与蛋白酶体的相互作用表面。

PROTEIN SCIENCE

IF5.2

2025-03-17

OAAI

Salomonsson, Johannes; Sjostrand, Linda; Eskilson, Arvid; Derbyshire, Dean; D'Arcy, Padraig; Sunnerhagen, Maria

PSMC6 regulation of ovarian cancer cisplatin resistance unravels a new mode for proteasome targeting PSMC6对卵巢癌顺铂耐药的调控揭示了泛素-蛋白酶体靶向的新模式

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES

IF10

2025-02-26

OAAI

Costantino, Matteo; Mirra, Luca; D'arcy, Padraig; Corno, Cristina; Carenini, Nives; Corna, Elisabetta; Gubat, Johannes; Ciniselli, Chiara M.; Pratesi, Pietro; Verderio, Paolo; Linder, Stig; Perego, Paola

Modulation of biological activities in adipose derived stem cells by histone deacetylation

SCIENTIFIC REPORTS

IF3.9

2025-01-29

OAAI

Abdallah, Sallam; Tabebi, Mouna; Qanadilo, Sawsan; Ali, Neserin; Wang, Jing; D'Arcy, Padraig; Zhong, Wen; Sjoberg, Folke; Elmasry, Moustafa; El-Serafi, Ahmed

Loss of the proteasomal deubiquitinase USP14 induces growth defects and a senescence phenotype in colorectal cancer cells

SCIENTIFIC REPORTS

IF3.9

2024-06-06

OAAI

Gubat, Johannes; Sjostrand, Linda; Selvaraju, Karthik; Telli, Kubra; D'Arcy, Padraig

The tumor suppressor p53 is a negative regulator of the carcinoma-associated transcription factor FOXQ1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-04-01

OAAI

Pizzolato, Giulia; Moparthi, Lavanya; Pagella, Pierfrancesco; Cantu, Claudio; D'Arcy, Padraig; Koch, Stefan

CRISPR/Cas9 screening identifies the proteasome subunit PSMC6 as key for the survival of cisplatin-resistant ovarian carcinoma cells

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Costantino, Matteo; D'arcy, Padraig; Mirra, Luca; Corno, Cristina; Beretta, Giovanni L.; Gubat, Johannes; Pratesi, Pietro; Ciniselli, Chiara M.; Verderio, Paolo; Linder, Stig; Perego, Paola

Feasibility of Coacervate-Like Nanostructure for Instant Drug Nanoformulation

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2023-03-28

OAAI

Zhu, Geyunjian H.; Azharuddin, Mohammad; Pramanik, Bapan; Roberg, Karin; Biswas, Sujoy Kumar; D'arcy, Padraig; Lu, Meng; Kaur, Apanpreet; Chen, Alexander; Dhara, Ashis Kumar; Chivu, Alexandru; Zhuang, Yunhui; Baker, Andrew; Liu, Xiewen; Fairen-Jimenez, David; Mazumder, Bismoy; Chen, Rongjun; Kaminski, Clemens F.; Schierle, Gabriele S. Kaminski; Hinkula, Jorma; Slater, Nigel K. H.; Patra, Hirak K.

Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action

FRONTIERS IN ONCOLOGY

IF3.3

2022-04-22

OAAI

Gubat, Johannes; Selvaraju, Karthik; Sjoestrand, Linda; Kumar Singh, Dhananjay; Turkina, Maria V.; Schmierer, Bernhard; Sabatier, Pierre; Zubarev, Roman A.; Linder, Stig; D'Arcy, Padraig

Caffeic acid phenethyl ester targets ubiquitin-specific protease 8 and synergizes with cisplatin in endometrioid ovarian carcinoma cells

BIOCHEMICAL PHARMACOLOGY

IF5.6

2022-03-01

PREAI

Colombo, Diego; Gatti, Laura; Sjostrand, Linda; Carenini, Nives; Costantino, Matteo; Corna, Elisabetta; Arrighetti, Noemi; Zuccolo, Marco; De Cesare, Michelandrea; Linder, Stig; D'Arcy, Padraig; Perego, Paola

Identification of proteasome inhibitors using analysis of gene expression profiles

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2020-12-01

OAAI

Mofers, Arjan; Selvaraju, Karthik; Gubat, Johannes; D 'Arcy, Padraig; Linder, Stig

Dissecting multi drug resistance in head and neck cancer cells using multicellular tumor spheroids

SCIENTIFIC REPORTS

IF3.9

2019-12-27

OAAI

Azharuddin, Mohammad; Roberg, Karin; Dhara, Ashis Kumar; Jain, Mayur Vilas; Darcy, Padraig; Hinkula, Jorma; Slater, Nigel K. H.; Patra, Hirak K.

Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system (vol 9, 9841, 2019)

SCIENTIFIC REPORTS

IF3.9

2019-11-20

OAAI

Selvaraju, Karthik; Mofers, Arjan; Pellegrini, Paola; Salomonsson, Johannes; Ahlner, Alexandra; Morad, Vivian; Hillert, Ellin-Kristina; Espinosa, Belen; Arner, Elias S. J.; Jensen, Lasse; Malmstrom, Jonas; Turkina, Maria V.; D'Arcy, Padraig; Walters, Michael A.; Sunnerhagen, Maria; Linder, Stig

Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system

SCIENTIFIC REPORTS

IF3.9

2019-07-08

OAAI

Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug

BIOCHIMIE

IF3

2019-07-01

121

OAAI

Zhang, Xiaonan; Selvaraju, Karthik; Saei, Amir Ata; D'Arcy, Padraig; Zubarev, Roman A.; Arner, Elias S. J.; Linder, Stig

Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation

CANCER LETTERS

IF10.1

2019-04-01

PREAI

Hillert, Ellin-Kristina; Brnjic, Slavica; Zhang, Xiaonan; Mazurkiewicz, Magdalena; Saei, Amir Ata; Mofers, Arjan; Selvaraj, Karthik; Zubarev, Roman; Linder, Stig; D'Arcy, Padraig

The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and Check for mitochondrial damage

BIOCHEMICAL PHARMACOLOGY

IF5.6

2018-10-01

PREAI

Zhang, Xiaonan; Pellegrini, Paola; Saei, Amir Ata; Hillert, Ellin-Kristina; Mazurkiewicz, Magdalena; Olofsson, Maria Hagg; Zubarev, Roman A.; D'Arcy, Padraig; Linder, Stig

A drug screening assay on cancer cells chronically adapted to acidosis

CANCER CELL INTERNATIONAL

IF6

2018-09-25

OAAI

Pellegrini, Paola; Serviss, Jason T.; Lundback, Thomas; Bancaro, Nicolo; Mazurkiewicz, Magdalena; Kolosenko, Iryna; Yu, Di; Haraldsson, Martin; D'Arcy, Padraig; Linder, Stig; De Milito, Angelo

Screening and characterization of drugs that inhibit the ubiquitin-proteasome system

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Selvaraju, Karthik; Mofers, Arjan; Pellegrini, Paola; Hillert, Ellin-Kristina; D'Arcy, Padraig; Linder, Stig

Inhibition of proteasome deubiquitinase activity prevents cytoprotective aggresome formation in cancer cells

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Hillert, Ellin-Kristina; Brjnic, Slavica; Mazurkiewicz, Magdalena; Larsson, Rolf; Fryknas, Marten; Swanton, Lisa; High, Stephen; Linder, Stig; D'Arcy, Padraig B.

研究方向