Patrick M. Dansette - Publications, H-index & Citations

Patrick M. Dansette

centre national de la recherche scientifique (cnrs)

51H指数

191论文数

7.4K被引数

收录论文 36

发表时间

Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-04-01

OAAI

Wang, Yong; Pigeon, Pascal; Li, Wei; Yan, Jiangkun; Dansette, Patrick M.; Othman, Mohamed; McGlinchey, Michael J.; Jaouen, Gerard

Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-07-01

OAAI

Dubois, Lilian; Pietrancosta, Nicolas; Cabaye, Alexandre; Fanget, Isabelle; Debacker, Cecile; Gilormini, Pierre-Andre; Dansette, Patrick M.; Dairou, Julien; Biot, Christophe; Froissart, Roseline; Goupil-Lamy, Anne; Bertrand, Hugues-Olivier; Acher, Francine C.; McCort-Tranchepain, Isabelle; Gasnier, Bruno; Anne, Christine

Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression

MOLECULAR PSYCHIATRY

IF10.1

2019-10-16

OAAI

Orrico-Sanchez, Alejandro; Chausset-Boissarie, Laetitia; Alves de Sousa, Rodolphe; Coutens, Basile; Rezai Amin, Sara; Vialou, Vincent; Louis, Franck; Hessani, Assia; Dansette, Patrick M.; Zornoza, Teodoro; Gruszczynski, Carole; Giros, Bruno; Guiard, Bruno P.; Acher, Francine; Pietrancosta, Nicolas; Gautron, Sophie

A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties

CHEMICAL SCIENCE

IF7.4

2018-01-01

OAAI

Wang, Yong; Dansette, Patrick M.; Pigeon, Pascal; Top, Siden; McGlinchey, Michael J.; Mansuy, Daniel; Jaouen, Gerard

Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation 二茂铁醌甲基化物-硫醇加合物作为新的抗增殖剂: 合成，二茂铁酚的代谢形成和氧化转化

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2016-06-08

OAAI

Wang, Yong; Richard, Marie-Aude; Top, Siden; Dansette, Patrick M.; Pigeon, Pascal; Vessieres, Anne; Mansuy, Daniel; Jaouen, Gerard

Bioactivation of Clopidogrel and Prasugrel: Factors Determining the Stereochemistry of the Thiol Metabolite Double Bond

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2015-05-21

PREAI

Dansette, Patrick M.; Levent, Dan; Hessani, Assia; Mansuy, Daniel

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites 他莫昔芬二茂铁类似物的氧化代谢: 代谢物的表征和抗增殖活性

CHEMMEDCHEM

IF3.4

2015-04-16

OAAI

Richard, Marie-Aude; Hamels, Didier; Pigeon, Pascal; Top, Siden; Dansette, Patrick M.; Lee, Hui Zhi Shirley; Vessieres, Anne; Mansuy, Daniel; Jaouen, Gerard

Thiolactone Sulfoxides as New Reactive Metabolites Acting as Bis-Electrophiles: Implication in Clopidogrel and Prasugrel Bioactivation

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2013-04-09

PREAI

Dansette, Patrick M.; Levent, Dan; Hessani, Assia; Bertho, Gildas; Mansuy, Daniel

Metabolic Activation of Prasugrel: Nature of the Two Competitive Pathways Resulting in the Opening of Its Thiophene Ring

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2012-04-18

PREAI

Dansette, Patrick M.; Rosi, Julien; Debernardi, Justine; Bertho, Gildas; Mansuy, Daniel

Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2011-12-01

117

PREAI

Dansette, Patrick M.; Rosi, Julien; Bertho, Gildas; Mansuy, Daniel

Paraoxonase-1 and clopidogrel efficacy

NATURE MEDICINE

IF50

2011-09-07

PREAI

Dansette, Patrick M.; Rosi, Julien; Bertho, Gildas; Mansuy, Daniel

Evaluation of Deuterium Labeled and Unlabeled Bis-methyl Glutathione Combined with Nano liquid Chromatography Mass Spectrometry to Screen and Characterize Reactive Drug Metabolites

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2011-03-04

PREAI

Defoy, Daniel; Dansette, Patrick M.; Neugebauer, Witold; Wagner, J. Richard; Klarskov, Klaus

Sulfenic acids as reactive intermediates in xenobiotic metabolism

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2011-03-01

PREAI

Mansuy, Daniel; Dansette, Patrick M.

Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2010-06-17

PREAI

Dansette, Patrick M.; Thebault, Stephanie; Bertho, Gildas; Mansuy, Daniel

Ferrocenyl Quinone Methides as Strong Antiproliferative Agents: Formation by Metabolic and Chemical Oxidation of Ferrocenyl Phenols

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2009-11-11

177

PREAI

Hamels, Didier; Dansette, Patrick M.; Hillard, Elizabeth A.; Top, Siden; Vessieres, Anne; Herson, Patrick; Jaouen, Gerard; Mansuy, Daniel

Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2009-01-26

PREAI

Dansette, Patrick M.; Libraire, Julie; Bertho, Gildas; Mansuy, Daniel

Determinants of cytochrome P4502C8 substrate binding -: Structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2008-06-01

160

OAAI

Schoch, Guillaume A.; Yano, Jason K.; Sansen, Stefaan; Dansette, Patrick M.; Stout, C. David; Johnson, Eric F.

Improvement of cyclophosphamide activation by CYP2B6 mutants:: From in silico to ex vivo

MOLECULAR PHARMACOLOGY

IF3

2008-04-01

PREAI

Nguyen, Thien-An; Tychopoulos, Marina; Bichat, Florence; Zimmermann, Clothilde; Flinois, Jean-Pierre; Diry, Monique; Ahlberg, Emelie; Delaforge, Marcel; Corcos, Laurent; Beaune, Philippe; Dansette, Patrick; Andre, Francois; de Waziers, Isabelle

Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2007-08-01

OAAI

Lafite, Pierre; Dijols, Sylvie; Zeldin, Darryl C.; Dansette, Patrick M.; Mansuy, Daniel

Kinetics of tienilic acid bioactivation and functional generation of drug-protein adducts in intact rat hepatocytes

BIOCHEMICAL PHARMACOLOGY

IF5.6

2005-12-01

PREAI

López García, MP; Dansette, PM; Coloma, J

研究方向