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A

Andreas Weihofen

university of luxembourg
H指数:22
被引数:4,141

个人简介

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教育背景

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工作经历

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荣誉奖项

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Discovery and Optimization of Thienopyrazine RNA-Splicing Modulators for the Treatment of Huntington’s Disease

发现和优化噻吩吡嗪类RNA剪接调节剂以治疗亨廷顿病

Journal of Medicinal Chemistry
IF6.8
2026-03-170
PRE
Chaofan Xu; Neeta Abraham; Nupur Bansal; Philippe N. Bolduc; Patrick Cullen; Thomas M. Carlile; Yirui Chen; Colin K. Choi; Rachelle Driscoll; Eric Stefan; Christina M. Gallo; Zhen Gao; Catherine L. Guardado; Guilherme Guimaraes; James Harvey; Sarah Huff; Dann Huh; Jessica Hurt; Melissa M. Kemp; Kwang Soo Lee; Joon Lee; Mukesh Lulla; Soumya Negi; Marta Nevalainen; Emily A. Peterson; Thomas J. Purgett; Joseph C. Santoro; Daniel R. Smith; Andreas Weihofen; Zain Yousaf; Magnus Pfaffenbach
Comparative assessment of binding and functional differences of clinical antibodies targeting α-synuclein in cellular models of Parkinson’s disease

临床抗体靶向α-突触核蛋白在帕金森病细胞模型中结合和功能差异的比较评估

Biomedicine & Pharmacotherapy
IF7.5
2025-06-180
PRE
YuTing Liu; Isin Dalkilic-Liddle; You Li; Benjamin A. Smith; Thomas O. Cameron; Joseph W. Arndt; Chao Quan; Andreas Lehmann; Daniel J. Apicco; Lori Hrdlicka; Andreas Weihofen; Warren D. Hirst; Edward D. Plowey; Paul H. Weinreb; Blake Pepinsky
Dose-dependent reduction of somatic expansions but not Htt aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111 mice
SCIENTIFIC REPORTS
IF3.9
2024-01-244
OAAI
Driscoll, Rachelle; Hampton, Lucas; Abraham, Neeta A.; Larigan, J. Douglas; Joseph, Nadine F.; Hernandez-Vega, Juan C.; Geisler, Sarah; Yang, Fu-Chia; Deninger, Matthew; Tran, David T.; Khatri, Natasha; Godinho, Bruno M. D. C.; Kinberger, Garth A.; Montagna, Daniel R.; Hirst, Warren D.; Guardado, Catherine L.; Glajch, Kelly E.; Arnold, H. Moore; Gallant-Behm, Corrie L.; Weihofen, Andreas
Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease

在帕金森病的播种/扩散小鼠模型中，神经变性和神经炎症是相关的，但独立于 α-突触核蛋白包涵体

GLIA
IF5.1
2022-01-2936
OAAI
Garcia, Pierre; Jurgens-Wemheuer, Wiebke; Huarte, Oihane Uriarte; Michelucci, Alessandro; Masuch, Annette; Brioschi, Simone; Weihofen, Andreas; Koncina, Eric; Coowar, Djalil; Heurtaux, Tony; Glaab, Enrico; Balling, Rudi; Sousa, Carole; Kaoma, Tony; Nicot, Nathalie; Pfander, Tatjana; Schulz-Schaeffer, Walter; Allouche, Ahmad; Fischer, Nicolas; Biber, Knut; Kleine-Borgmann, Felix; Mittelbronn, Michel; Ostaszewski, Marek; Schmit, Kristopher J.; Buttini, Manuel
α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease

Α-突触核蛋白反义寡核苷酸作为帕金森病的疾病缓解疗法

JCI INSIGHT
IF6.1
2021-03-0878
OA
Cole, Tracy A.; Zhao, Hien; Collier, Timothy J.; Sandoval, Ivette; Sortwell, Caryl E.; Steece-Collier, Kathy; Daley, Brian F.; Booms, Alix; Lipton, Jack; Welch, Mackenzie; Berman, Melissa; Jandreski, Luke; Graham, Danielle; Weihofen, Andreas; Celano, Stephanie; Schulz, Emily; Cole-Strauss, Allyson; Luna, Esteban; Quach, Duc; Mohan, Apoorva; Bennett, C. Frank; Swayze, Eric E.; Kordasiewicz, Holly B.; Luk, Kelvin C.; Paumier, Katrina L.
The Parkinson's disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release

帕金森氏病相关基因ITPKB通过调节ER到线粒体的钙释放来防止 α-突触核蛋白聚集

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-12-2137
OAAI
Apicco, Daniel J.; Shlevkov, Evgeny; Nezich, Catherine L.; Tran, David T.; Guilmette, Edward; Nicholatos, Justin W.; Bantle, Collin M.; Chen, Yi; Glajch, Kelly E.; Abraham, Neeta A.; Dang, Lan T.; Kaynor, G. Campbell; Tsai, Ellen A.; Nguyen, Khanh-Dung H.; Groot, Joost; Liu, YuTing; Weihofen, Andreas; Hurt, Jessica A.; Runz, Heiko; Hirst, Warren D.
Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models
NEUROBIOLOGY OF DISEASE
IF5.6
2019-04-01151
OAAI
Weihofen, Andreas; Liu, YuTing; Arndt, Joseph W.; Huy, Christian; Quan, Chao; Smith, Benjamin A.; Baeriswyl, Jean-Luc; Cavegn, Nicole; Senn, Luzia; Su, Lihe; Marsh, Galina; Auluck, Pavan K.; Montrasio, Fabio; Nitsch, Roger M.; Hirst, Warren D.; Cedarbaum, Jesse M.; Pepinsky, R. Blake; Grimm, Jan; Weinreb, Paul H.

研究方向

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W
Warren D. Hirst
H 指数:53论文数:130被引数:8,913
Y
Yuting Liu
H 指数:12论文数:43被引数:781
B
Bruno Martoglio
H 指数:34论文数:91被引数:5,018
D
Dennis J. Selkoe
H 指数:171论文数:676被引数:15.1万
E
Eric E. Swayze
H 指数:61论文数:254被引数:1.4万
H
Hien Zhao
H 指数:16论文数:50被引数:1,642
M
Marius K. Lemberg
H 指数:37论文数:87被引数:1.1万
H
Holly Kordasiewicz
H 指数:38论文数:160被引数:7,899
L
Laura A. Volpicelli‐Daley
H 指数:45论文数:108被引数:1.0万
A
Andrew B. West
H 指数:68论文数:215被引数:1.7万