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E

Eric E. Swayze

(tsimikas, morgan, sharma, lin, mullick, prakash, swayze, prohaska)
H指数:61
被引数:1.4万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Transient acute neuronal activation response caused by high concentrations of oligonucleotides in the cerebral spinal fluid

脑脊液中寡核苷酸高浓度引起的短暂急性神经元激活反应

Nucleic Acids Research
IF13.1
2026-02-102
PRE
Bravo-Hernandez, Mariana; Mazur, Curt; Chen, Hao; Fradkin, Linda; Searcy, Justin; Burel, Sebastien; Kelly, Mackenzie; Bruening, Dona; O'Rourke, Jacqueline G.; Cai, Yuhang; Nguyen, Jonathon; Berman-Booty, Lisa; Cummins, Lendell; Gaus, Hans; Powers, Berit; Zhao, Hien T.; Jafar-Nejad, Paymaan; Henry, Scott; Swayze, Eric E.; Kordasiewicz, Holly B.
Acute neuronal inhibition response caused by phosphorothioate antisense oligonucleotides following local delivery to the central nervous system

磷硫酰化反义寡核苷酸经局部递送至中枢神经系统后引起的急性神经元抑制反应

Nucleic Acids Research
IF13.1
2026-01-012
PRE
O'Rourke, Jacqueline G.; Bachmann, Gemma; Mazur, Curt; Zhou, Keming; Platoshyn, Oleksandr; Bravo Hernandez, Mariana; Klein, Stephanie K.; Nguyen, Jonathon; Burel, Sebastien; Hoffmaster, Christine; Zanardi, Thomas; Jafar-nejad, Paymaan; Marsala, Martin; Henry, Scott P.; Swayze, Eric E.; Powers, Berit; Kordasiewicz, Holly B.
Single alkyl phosphonate modification of the siRNA backbone in the seed region enhances specificity and therapeutic profile

单烷基膦酸酯修饰的siRNA骨架在种子区域增强了特异性和治疗谱

NUCLEIC ACIDS RESEARCH
IF13.1
2025-08-120
PRE
Nikan, Mehran; Li, Qingfeng; Tanowitz, Michael; Li, Hongda; Damle, Sagar; Annoual, Marie; Galindo-Murillo, Rodrigo; Low, Audrey; Klein, Stephanie; Quirk, Clare; Vasquez, Guillermo; Wan, W. Brad; Watt, Andrew T.; Migawa, Michael T.; Swayze, Eric E.; Prakash, Thazha P.
Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial (vol 29, pg 1437, 2023)
NATURE MEDICINE
IF50
2023-10-160
OAAI
Mummery, Catherine J.; Borjesson-Hanson, Anne; Blackburn, Daniel J.; Vijverberg, Everard G. B.; De Deyn, Peter Paul; Ducharme, Simon; Jonsson, Michael; Schneider, Anja; Rinne, Juha O.; Ludolph, Albert C.; Bodenschatz, Ralf; Kordasiewicz, Holly; Swayze, Eric E.; Fitzsimmons, Bethany; Mignon, Laurence; Moore, Katrina M.; Yun, Chris; Baumann, Tiffany; Li, Dan; Norris, Daniel A.; Crean, Rebecca; Graham, Danielle L.; Huang, Ellen; Ratti, Elena; Bennett, C. Frank; Junge, Candice; Lane, Roger M.
Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial

Tau靶向反义寡核苷酸MAPTRx治疗轻度阿尔茨海默病: 1b期，随机，安慰剂对照试验

NATURE MEDICINE
IF50
2023-04-24109
OAAI
Mummery, Catherine J.; Borjesson-Hanson, Anne; Blackburn, Daniel J.; Vijverberg, Everard G. B.; De Deyn, Peter Paul; Ducharme, Simon; Jonsson, Michael; Schneider, Anja; Rinne, Juha O.; Ludolph, Albert C.; Bodenschatz, Ralf; Kordasiewicz, Holly; Swayze, Eric E.; Fitzsimmons, Bethany; Mignon, Laurence; Moore, Katrina M.; Yun, Chris; Baumann, Tiffany; Li, Dan; Norris, Daniel A.; Crean, Rebecca; Graham, Danielle L.; Huang, Ellen; Ratti, Elena; Bennett, C. Frank; Junge, Candice; Lane, Roger M.
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides
NUCLEIC ACIDS RESEARCH
IF13.1
2021-08-2077
OAAI
Anderson, Brooke A.; Freestone, Graeme C.; Low, Audrey; De-Hoyos, Cheryl L.; Drury, William J., III; Ostergaard, Michael E.; Migawa, Michael T.; Fazio, Michael; Wan, W. Brad; Berdeja, Andres; Scandalis, Eli; Burel, Sebastien A.; Vickers, Timothy A.; Crooke, Stanley T.; Swayze, Eric E.; Liang, Xuehai; Seth, Punit P.
α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease

Α-突触核蛋白反义寡核苷酸作为帕金森病的疾病缓解疗法

JCI INSIGHT
IF6.1
2021-03-0878
OA
Cole, Tracy A.; Zhao, Hien; Collier, Timothy J.; Sandoval, Ivette; Sortwell, Caryl E.; Steece-Collier, Kathy; Daley, Brian F.; Booms, Alix; Lipton, Jack; Welch, Mackenzie; Berman, Melissa; Jandreski, Luke; Graham, Danielle; Weihofen, Andreas; Celano, Stephanie; Schulz, Emily; Cole-Strauss, Allyson; Luna, Esteban; Quach, Duc; Mohan, Apoorva; Bennett, C. Frank; Swayze, Eric E.; Kordasiewicz, Holly B.; Luk, Kelvin C.; Paumier, Katrina L.

研究方向

暂未获取到该数据
P
Punit P. Seth
H 指数:50论文数:166被引数:8,380
T
Thazha P. Prakash
H 指数:51论文数:144被引数:8,180
H
Holly Kordasiewicz
H 指数:38论文数:160被引数:7,910
H
Hans Gaus
H 指数:38论文数:78被引数:4,821
M
Michael T. Migawa
H 指数:29论文数:61被引数:3,414
C
C. Frank Bennett
H 指数:100论文数:332被引数:4.7万
M
Michael E. Østergaard
H 指数:28论文数:63被引数:2,870
R
Richard H. Griffey
H 指数:46论文数:226被引数:9,426
G
Guillermo Vasquez
H 指数:17论文数:83被引数:1,464
A
Andrés Berdeja
H 指数:17论文数:40被引数:1,733