David L. Selwood - Publications, H-index & Citations

David L. Selwood

universidad loyola andalucía

38H指数

201论文数

5.1K被引数

收录论文 68

发表时间

Pathogenic variants in the autophagy-tethering factor EPG5 drive neurodegeneration through mitochondrial dysfunction and innate immune activation EPG5自噬连接因子中的致病性变异通过线粒体功能障碍和固有免疫激活驱动神经退行性变

Nature Communications

IF15.7

2026-05-01

PREAI

Singh, Kritarth; Dafsari, Hormos Salimi; Gillham, Olivia; Chi, Haoyu; Mandzhukova, Ivet; Kourouzidou, Ioanna; Sheshadri, Preethi; Chung, Chih-Yao; Pingitore, Valeria; Vansenne, Fleur; Selwood, David L.; Pendin, Diana; Szabadkai, Gyorgy; Fanto, Manolis; Jungbluth, Heinz; Duchen, Michael R.

Quinoline-Based Neuropilin-1 Antagonists Exhibit a Pure Antagonist Profile and Block Vascular Endothelial Growth Factor-Induced Pain 喹啉类神经毡蛋白-1拮抗剂表现出纯拮抗剂特性并阻断血管内皮生长因子诱导的疼痛

ACS Pharmacology & Translational Science

IF3.7

2025-10-29

OAAI

Sara Hestehave; Silvia Dragoni; Philip Fallon; Filipa Mota; Aida Calderon-Rivera; Kimberly Gomez; Jonathan Powell; Anastasia Patsiarika; Tifelle Reisinger; Stuart Crosby; A.W. Edith Chan; David Steadman; Natalie Winfield; Ashley Jarvis; John Martin; Ian C. Zachary; Paul Frankel; Snezana Djordjevic; Christiana Ruhrberg; Rajesh Khanna; David L. Selwood

The case for targeting latent and lytic Epstein-Barr virus infection in multiple sclerosis 靶向潜伏和裂解性Epstein-Barr病毒感染在多发性硬化中的案例

Brain

IF11.7

2025-05-06

OAAI

Gavin Giovannoni; Louisa James; Adekunle A Adeniran; Julian Gold; Lawrence S Young; David L Selwood; David Baker; Ruth Dobson

Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration

SCIENCE ADVANCES

IF12.5

2024-07-12

OAAI

Pingitore, Valeria; Pancholi, Jessica; Hornsby, Thomas W.; Warne, Justin; Pryce, Gareth; Mccormick, Laura J.; Hill, Julia; Bhosale, Gauri; Peng, Jing; Newton, Lydia S.; Towers, Greg J.; Coles, Simon J.; Chan, Ah Wing Edith; Duchen, Michael R.; Szabadkai, Gyorgy; Baker, David; Selwood, David L.

Neuroprotection in an Experimental Model of Multiple Sclerosis via Opening of Big Conductance, Calcium-Activated Potassium Channels

PHARMACEUTICALS

IF4.8

2023-07-07

OAAI

Pryce, Gareth; Sisay, Sofia; Giovannoni, Gavin; Selwood, David L.; Baker, David

Therapeutic Validation of GEF-H1 Using a De Novo Designed Inhibitor in Models of Retinal Disease

CELLS

IF5.2

2022-05-24

OAAI

Mills, Clare; Hemkemeyer, Sandra A.; Alimajstorovic, Zerin; Bowers, Chantelle; Eskandarpour, Malihe; Greenwood, John; Calder, Virginia; Chan, A. W. Edith; Gane, Paul J.; Selwood, David L.; Matter, Karl; Balda, Maria S.

Studies on the function of myeloid-derived Neuropilin-1 in glioma: a focus on tumor hypoxia

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Radin, Daniel P.; Caponegro, Michael; Smith, Gregory; Moushiaveshi, Victoria; Selwood, David; Tsirka, Stella

A Series of Substituted Bis-Aminotriazines Are Activators of the Natriuretic Peptide Receptor C

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-03-25

OAAI

Smith, Robert J.; Perez-Ternero, Cristina; Conole, Daniel; Martin, Capucine; Myers, Samuel H.; Hobbs, Adrian J.; Selwood, David L.

VSN16S, an agonist of the cannabinoid receptor, reduces IOP profiles and exhibits neuroprotective properties in a rat model of glaucoma

ACTA OPHTHALMOLOGICA

IF2.8

2022-01-03

PREAI

Guo, Li; Luong, Vy; Gregson, Aaron; Baker, David; Selwood, David; Cordeiro, M. Francesca

Reversal of behavioural phenotype by the cannabinoid-like compound VSN16R in fragile X syndrome mice

BRAIN

IF11.7

2021-07-01

OAAI

Hurley, Michael J.; Deacon, Robert M. J.; Chan, A. W. Edith; Baker, David; Selwood, David L.; Cogram, Patricia

Hepatitis C virus exploits cyclophilin A to evade PKR

ELIFE

IF0

2020-06-16

OAAI

Colpitts, Che C.; Ridewood, Sophie; Schneiderman, Bethany; Warne, Justin; Tabata, Keisuke; Ng, Caitlin F.; Bartenschlager, Ralf; Selwood, David L.; Towers, Greg J.

The β4-Subunit of the Large-Conductance Potassium Ion Channel KCa1.1 Regulates Outflow Facility in Mice

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2020-03-23

OAAI

Bertrand, Jacques A.; Schicht, Martin; Stamer, W. Daniel; Baker, David; Sherwood, Joseph M.; Luetjen-Drecoll, Elke; Selwood, David L.; Overby, Darryl R.

Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin-1 binding of small molecules

DRUG DEVELOPMENT RESEARCH

IF4.2

2020-01-20

OAAI

Conole, Daniel; Chou, Yi-Tai; Patsiarika, Anastasia; Nwabo, Valery; Dinnitriou, Eleni; Soudy, Christelle; Mota, Filipa; Djordjevic, Snezana; Selwood, David L.

A new patient-derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α-dystroglycan

EMBO REPORTS

IF6.2

2019-09-30

OAAI

Kim, Jihee; Lana, Beatrice; Torelli, Silvia; Ryan, David; Catapano, Francesco; Ala, Pierpaolo; Luft, Christin; Stevens, Elizabeth; Konstantinidis, Evangelos; Louzada, Sandra; Fu, Beiyuan; Paredes-Redondo, Amaia; Chan, A. W. Edith; Yang, Fengtang; Stemple, Derek L.; Liu, Pentao; Ketteler, Robin; Selwood, David L.; Muntoni, Francesco; Lin, Yung-Yao

Commentary: Reproducible science, why protocols matter

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2019-07-25

PREAI

Selwood, David L.

The Cannabinoid-Like Compound, VSN16R, Acts on Large Conductance, Ca2+-Activated K+ Channels to Modulate Hippocampal CA1 Pyramidal Neuron Firing

PHARMACEUTICALS

IF4.8

2019-07-04

OAAI

Tabatabaee, Setareh; Baker, David; Selwood, David L.; Whalley, Benjamin J.; Stephens, Gary J.

N10-carbonyl-substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2019-06-12

OAAI

Keynes, Robert G.; Karchevskaya, Anastasia; Riddall, Dieter; Griffiths, Charmaine H.; Bellamy, Tomas C.; Chan, A. W. Edith; Selwood, David L.; Garthwaite, John

Mitochondrial Permeability Transition: A Molecular Lesion with Multiple Drug Targets

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2019-01-01

151

OAAI

Briston, Thomas; Selwood, David L.; Szabadkai, Gyorgy; Duchen, Michael R.

Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2018-10-10

OAAI

Conole, Daniel; Myers, Samuel H.; Mota, Filipa; Hobbs, Adrian J.; Selwood, David L.

Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-04-12

OAAI

Powell, Jonathan; Mota, Filipa; Steadman, David; Soudy, Christelle; Miyauchi, Jeremy T.; Crosby, Stuart; Jarvis, Ashley; Reisinger, Tifelle; Winfield, Natalie; Evans, Graham; Finniear, Aled; Yelland, Tamas; Chou, Yi-Tai; Chan, A. W. Edith; O'Leary, Andrew; Cheng, Lili; Liu, Dan; Fotinou, Constantina; Milagre, Carla; Martin, John F.; Jin, Haiyan; Franke, Paul; Djordjevic, Snezana; Tsirka, Stella E.; Zachary, Ian C.; Selwood, David L.

研究方向