Lbachir BenMohamed - Publications, H-index & Citations

Lbachir BenMohamed

university of california irvine

50H指数

220论文数

6.1K被引数

收录论文 89

发表时间

High Frequencies of Senescent and Exhausted Natural Killer Cells and SARS-CoV-2-Specific Memory CD8+ T Cells Distinguish Critically Ill from Asymptomatic Unvaccinated COVID-19 Patients 老年和耗竭的自然杀伤细胞以及SARS-CoV-2特异性记忆CD8+ T细胞的高频率可区分危重与无症状未接种疫苗的COVID-19患者

Viruses-Basel

IF3.5

2026-08-30

OAAI

Ruchi Srivastava; Swayam Prakash; Sweta Karan; Lbachir BenMohamed

Multi-antigen coronavirus vaccine induces potent and durable cross-protection against multiple SARS-CoV-2 variants 多抗原冠状病毒疫苗诱导对多种SARS-CoV-2变体强效且持久的交叉保护

npj Vaccines

IF6.5

2026-08-18

OAAI

Swayam Prakash; Nisha R. Dhanushkodi; Afshana Quadiri; Hawa Vahed; Aziz A. Chentoufi; Pierre-Gregoire Coulon; Izabela Coimbra Ibraim; Assia El Babsiri; Delia F. Tifrea; Cesar J. Figueroa; Daniel Gil; Jeffrey B. Ulmer; Lbachir BenMohamed

CCL25 chemokine promotes antiviral tissue resident CD4+ and CD8+ effector memory TRM cells associated with a reduction of ocular herpes infection and disease: a potential gut–eye axis in herpes immunity CCL25趋化因子促进抗病毒组织驻留CD4+和CD8+效应记忆TRM细胞，与眼部疱疹感染和疾病的减少相关：疱疹免疫中潜在的肠道-眼轴

Frontiers in Immunology

IF5.9

2026-07-20

OAAI

AR Azizur Rahman; SP Swayam Prakash; SK Sweta Karan; SX Sarah Xue Le Ng; GP Gina Park; CM Chhaya Maurya; AG America Garcia; KI Khan Intharachalit; JH Junseong Hwang; CT Celine Tze Yao Tang; RA Reilly Andrew Chow; BS Baverly Sabathini Suoth; EJ Emma Jane Liao; LB Lbachir BenMohamed

Role of mucosal chemokines in the development of tissue-resident CD4+ and CD8+ TRM cells to fend off herpes simplex infections 黏膜趋化因子在组织驻留CD4+和CD8+ TRM细胞发育以抵御单纯疱疹感染中的作用

Frontiers in Immunology

IF5.9

2026-02-19

OAAI

Lekbach, Yassir; Chentoufi, Aziz A.; Prakash, Swayam; Karan, Sweta; Quadiri, Afshana; Hormi-Carver, Kathy K.; Dorotta, Joshua Christian; BenMohamed, Lbachir

Artificial intelligence-; organoid-; and organ-on-chip-powered models to improve pre-clinical animal testing of vaccines and immunotherapeutics: potential; progress; and challenges 人工智能-、类器官-以及芯片上器官驱动的模型，以改进疫苗和免疫疗法的临床前动物测试：潜力、进展与挑战

Frontiers in Artificial Intelligence

IF4.7

2025-10-31

OAAI

Elhoucine Elfatimi; Yassir Lekbach; Swayam Prakash; Sweta Karan; Joshua Christian Dorotta; America Garcia; Beverly Sabathini Suoth; Chhaya Maurya; Etinosa Yvette Omorogieva; Sarah Xue Le Ng; Emma Jane Liao; Reilly Andrew Chow; Lbachir BenMohamed

Insights into Persistent SARS-CoV-2 Reservoirs in Chronic Long COVID 对慢性长期COVID中持续性SARS-CoV-2储库的见解

Viruses 2025, Vol. 17, Page 1310

IF3.5

2025-09-29

OAAI

Swayam Prakash; Sweta Karan; Yassir Lekbach; Delia F. Tifrea; Cesar J. Figueroa; Jeffrey B. Ulmer; James F. Young; Greg Glenn; Daniel Gil; Trevor M. Jones; Robert R. Redfield; Lbachir BenMohamed

The Path Towards Effective Long-Lasting Tissue-Targeted Prime/Pull/Keep Herpes Simplex Therapeutic Vaccines 实现长效组织靶向性HSV（单纯疱疹病毒）治疗性疫苗的“三步法”路径

Vaccines 2025, Vol. 13, Page 908

IF3.4

2025-08-28

OAAI

Afshana Quadiri; Yassir Lekbach; Elhoucine Elfatimi; Swayam Prakash; Hawa Vahed; Sweta Karan; Azizur Rehman; Sarah Xue Le Ng; Chhaya Maurya; Reilly Chow; Lbachir BenMohamed

Artificial intelligence and machine learning in the development of vaccines and immunotherapeutics—yesterday; today; and tomorrow 人工智能和机器学习在疫苗和免疫治疗剂开发中的应用——昨日；今日；明日

Frontiers in Artificial Intelligence

IF4.7

2025-07-28

OAAI

Elhoucine Elfatimi; Yassir Lekbach; Swayam Prakash; Lbachir BenMohamed

A pan-beta-coronavirus vaccine bearing conserved and asymptomatic B- and T-cell epitopes protects against highly pathogenic Delta and highly transmissible Omicron SARS-CoV-2 variants 一种携带保守性和无症状B细胞和T细胞表位的泛β冠状病毒疫苗，可抵抗高致病性Delta和高传染性Omicron SARS-CoV-2变异株

Human Vaccines & Immunotherapeutics

IF3.5

2025-07-04

OAAI

Hawa Vahed; Swayam Prakash; Afshana Quadiri; Izabela Coimbra Ibraim; Etinosa Omorogieva; Swena Patel; Jimmy Tadros; Emma Jane Liao; Lauren Lau; Aziz A. Chentoufi; Anthony B. Nesburn; Baruch D. Kuppermann; Jeffrey B. Ulmer; Daniel Gil; Lbachir BenMohamed

Dysfunctional Senescent Herpes Simplex Virus-Specific CD57+CD8+ T Cells Are Associated with Symptomatic Recurrent Ocular Herpes in Humans 功能失调的衰老型单纯疱疹病毒特异性CD57+CD8+ T细胞与人类有症状复发性眼疱疹相关

VIRUSES-BASEL

IF3.5

2025-04-24

OAAI

Chentoufi, Aziz A.; Khan, Arif A.; Srivastava, Ruchi; Karan, Sweta; Lekbach, Yassir; Vahed, Hawa; BenMohamed, Lbachir

A tissue-targeted prime/pull/keep therapeutic herpes simplex virus vaccine protects against recurrent ocular herpes infection and disease in HLA-A*0201 transgenic rabbits

JOURNAL OF VIROLOGY

IF3.8

2025-04-01

OAAI

Chentoufi, Aziz A.; Prakash, Swayam; Vahed, Hawa; Karan, Sweta; Quadiri, Afshana; Nesburn, Anthony B.; Benmohamed, Lbachir

Therapeutic mucosal vaccination of herpes simplex virus type 2 infected guinea pigs with an adenovirus-based vaccine expressing the ribonucleotide reductase 2 and glycoprotein D induces local tissue-resident CD4+and CD8+TRM cells associated with protection against recurrent genital herpes 用表达核糖核苷酸还原酶2和糖蛋白D的腺病毒载体疫苗对单纯疱疹病毒2型感染的豚鼠进行治疗性黏膜疫苗接种，可诱导与预防复发性生殖器疱疹相关的局部组织驻留CD4+和CD8+TRM细胞。

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-03-26

OAAI

Quadiri, Afshana; Prakash, Swayam; Vahed, Hawa; Tadros, Jimmy Medhat; Sun, Miyo; Hormi-Carver, Kathy K.; Patel, Swena Jignesh; BenMohamed, Lbachir

Dynamics of spike-specific neutralizing antibodies across five-year emerging SARS-CoV-2 variants of concern reveal conserved epitopes that protect against severe COVID-19 五年新兴SARS-CoV-2变异中刺突特异性中和抗体的动态变化揭示了保护免受严重新型冠状病毒肺炎的保守表位

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-02-18

OAAI

Zayou, Latifa; Prakash, Swayam; Vahed, Hawa; Dhanushkodi, Nisha Rajeswari; Quadiri, Afshana; Belmouden, Ahmed; Lemkhente, Zohra; Chentoufi, Aziz; Gil, Daniel; Ulmer, Jeffrey B.; Benmohamed, Lbachir

A Spike-Based mRNA Vaccine Encapsulated in Phospholipid 1,2-Dioleoyl-sn-Glycero-3-PhosphoEthanolamine Containing Lipid Nanoparticles Induced Potent B- and T-Cell Responses Associated with Protection Against SARS-CoV-2 Infection and COVID-19-like Symptoms in Hamsters

VACCINES

IF3.4

2025-01-08

OAAI

Quadiri, Afshana; Prakash, Swayam; Zayou, Latifa; Dhanushkodi, Nisha Rajeswari; Chilukuri, Amruth; Ryan, Gemma; Wang, Kelly; Vahed, Hawa; Chentoufi, Aziz A.; Benmohamed, Lbachir

Antigen Delivery Platforms for Next-Generation Coronavirus Vaccines 下一代冠状病毒疫苗的抗原递送平台

VACCINES

IF3.4

2024-12-31

OAAI

Chentoufi, Aziz A.; Ulmer, Jeffrey B.; Benmohamed, Lbachir

Therapeutic prime/pull vaccination of HSV-2-infected guinea pigs with the ribonucleotide reductase 2 (RR2) protein and CXCL11 chemokine boosts antiviral local tissue-resident and effector memory CD4+ and CD8+ T cells and protects against recurrent genital herpes 用核糖核苷酸还原酶2 (RR2) 蛋白和CXCL11趋化因子对HSV-2-infected豚鼠进行治疗性初免/拉动疫苗接种可增强抗病毒局部组织驻留和效应子记忆CD4和CD8 T细胞，并预防复发性生殖器疱疹

JOURNAL OF VIROLOGY

IF3.8

2024-05-14

OAAI

Quadiri, Afshana; Prakash, Swayam; Dhanushkodi, Nisha Rajeswari; Singer, Mahmoud; Zayou, Latifa; Shaik, Amin Mohammed; Sun, Miyo; Suzer, Berfin; Lau, Lauren Su Lin; Chilukurri, Amruth; Vahed, Hawa; Schaefer, Hubert; Benmohamed, Lbachir

High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients 在未接种疫苗的新型冠状病毒肺炎患者中，高频率的 α 普通感冒冠状病毒/SARS-CoV-2交叉反应功能性CD4和CD8记忆T细胞与保护免受症状性和致命性SARS-CoV-2感染有关

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-03-28

OAAI

Coulon, Pierre-Gregoire; Prakash, Swayam; Dhanushkodi, Nisha R.; Srivastava, Ruchi; Zayou, Latifa; Tifrea, Delia F.; Edwards, Robert A.; Figueroa, Cesar J.; Schubl, Sebastian D.; Hsieh, Lanny; Nesburn, Anthony B.; Kuppermann, Baruch D.; Bahraoui, Elmostafa; Vahed, Hawa; Gil, Daniel; Jones, Trevor M.; Ulmer, Jeffrey B.; Benmohamed, Lbachir

Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern 基于高度保守的人B、CD4和CD8 T细胞表位的疫苗对多种SARS-CoV-2变异引起的严重感染、疾病和死亡的交叉保护作用

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-01-22

OAAI

Prakash, Swayam; Dhanushkodi, Nisha R.; Zayou, Latifa; Ibraim, Izabela Coimbra; Quadiri, Afshana; Coulon, Pierre Gregoire; Tifrea, Delia F.; Suzer, Berfin; Shaik, Amin Mohammed; Chilukuri, Amruth; Edwards, Robert A.; Singer, Mahmoud; Vahed, Hawa; Nesburn, Anthony B.; Kuppermann, Baruch D.; Ulmer, Jeffrey B.; Gil, Daniel; Jones, Trevor M.; BenMohamed, Lbachir

Antiviral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and Syrian Golden Hamster Models Rage-ig蛋白对K18-hACE2小鼠和叙利亚金黄仓鼠模型中显示的多种SARS-CoV-2变异的抗病毒和抗炎治疗作用

JOURNAL OF IMMUNOLOGY

IF3.4

2024-01-05

OAAI

Dhanushkodi, Nisha Rajeswari; Prakash, Swayam; Quadiri, Afshana; Zayou, Latifa; Srivastava, Ruchi; Shaik, Amin Mohammed; Suzer, Berfin; Ibraim, Izabela Coimbra; Landucci, Gary; Tifrea, Delia F.; Singer, Mahmoud; Jamal, Leila; Edwards, Robert A.; Vahed, Hawa; Brown, Lawrence; Benmohamed, Lbachir

A multi-epitope/CXCL11 prime/pull coronavirus mucosal vaccine boosts the frequency and the function of lung-resident memory CD4+ and CD8+ T cells and enhanced protection against COVID-19-like symptoms and death caused by SARS-CoV-2 infection 多表位/CXCL11 prime/pull冠状病毒粘膜疫苗可提高肺部记忆性CD4和CD8 T细胞的频率和功能，并增强对SARS-CoV-2感染引起的COVID-19-like症状和死亡的保护

JOURNAL OF VIROLOGY

IF3.8

2023-12-21

OAAI

Zayou, Latifa; Prakash, Swayam; Dhanushkodi, Nisha Rajeswari; Quadiri, Afshana; Ibraim, Izabela Coimbra; Singer, Mahmoud; Salem, Amirah; Shaik, Amin Mohammed; Suzer, Berfin; Chilukuri, Amruth; Tran, Jennifer; Nguyen, Pauline Chau; Sun, Miyo; Hormi-Carver, Kathy K.; Belmouden, Ahmed; Vahed, Hawa; Gil, Daniel; Ulmer, Jeffrey B.; Benmohamed, Lbachir

研究方向