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Till Acker

University of Giessen

53H指数
193论文数
1.5W被引数
收录论文 76
发表时间
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Interlaboratory performance testing on EPIC v2.0 CNS tumor profiling demonstrates high reproducibility of tumor classification but reveals the need for harmonized copy number variation reporting实验室间性能测试对EPIC v2.0 CNS肿瘤分型的分析表明肿瘤分类具有高度可重复性，但揭示了需要对拷贝数变异报告进行标准化
errBrain Pathology
IF6.2
err2026-08-02
err0
errOAAI
errKatrin Mauch-Mücke; Christin Siewert; Lora Dimitrova; Sandra Pohl; Brendan Osberg; Annika K. Wefers; Julia Lorenz; Tanja Rothhammer-Hampl; Till Acker; Alonso Barrantes-Freer
err分享
err收藏
Distinct molecular subgroups in pediatric and young-onset meningiomas require age-adapted risk stratification儿童及年轻起病型脑膜瘤存在不同的分子亚群，需采用年龄适应性的风险分层策略
errNature Communications
IF15.7
err2026-07-14
err0
errOAAI
errNatalie Berghaus; Arnault Tauziède-Espariat; Thomas Hielscher; Dilan Savran; Daniel Schrimpf; Kirsten Göbel; Eric Stutheit-Zhao; Lukas Friedrich; Felix Keller; Fuat Kaan Aras; Filippo Nozzoli; Dominik Sturm; Christine L. White; Simone Schmid; Christian Mawrin; Julia E. Neumann; Till Acker; Rudi Beschorner; Christian Hartmann; Irem Saribiyik; Arda Inan; Ayça Erşen-Danyeli; Mariëtte E. G. Kranendonk; Sybren L. N. Maas; Eelke M. Bos; Eleonora Aronica; Saskia M. Peerdeman; Nikki B. Thuijs; Angelika Mühlebner; Benno Kusters; Wilfred F. A. den Dunnen; Cinzia E. Lavarino; Stéphanie Puget; Jason Chiang; Sonika Dahiya; Melike Pekmezci; Arie Perry; Oluwadamilola Akanji; Miriam Ratliff; Christel Herold-Mende; Sandro M. Krieg; Wolfgang Wick; Stefan M. Pfister; Pieter Wesseling; Andreas von Deimling; Pascale Varlet; Felix Sahm; Philipp Sievers
err分享
err收藏
Hetairos is a histology-based artificial intelligence model for predicting central nervous system tumor methylation subtypesHetairos是一种基于组织学的人工智能模型，用于预测中枢神经系统肿瘤甲基化亚型
errNature Cancer
IF28.5
err2026-06-10
err0
errOAAI
errDarui Jin; Artem Shmatko; Areeba Patel; Samuel Rutz; Lukas Friedrich; Rouzbeh Banan; Ramin Rahmanzade; Philipp Sievers; Stefan Hamelmann; Daniel Schrimpf; Kirsten Göbel; Henri Bogumil; Sybren L. N. Maas; Martin Sill; Felix E. Hinz; Abigail K. Suwala; Felix Keller; Antje Habel; Gleb Rukhovich; Ferdinand Zettl; Obada T. Alhalabi; Sebastian Ille; Jannik Sehring; Daniel Amsel; Benedikt Wiestler; Pedro Piovesan Lago; Bogdana Suchorska; Olfat Ahmad; Dominik Sturm; David Reuss; Pieter Wesseling; Adelheid Wöhrer; Frank L. Heppner; Ingmar Blümcke; Claire Delbridge; Martin Jakobs; Christel Herold-Mende; Sandro M. Krieg; Wolfgang Wick; David T. W. Jones; Stefan M. Pfister; Maysa Al-Hussaini; Yanghao Hou; Felipe D’Almeida Costa; Leonille Schweizer; Luca Bertero; Till Acker; Arnault Tauziede-Espariat; Pascale Varlet; Doron Merkler; Kristof Egervari; Hildegard Dohmen; Pablo Zoroquiain; Roger Gejman; Sebastian Brandner; Xiangzhi Bai; Andreas von Deimling; Felix Sahm; Moritz Gerstung
err分享
err收藏
Loss of meningothelial identity and mesenchymal fate switching in NF2-mutant meningiomas
errActa Neuropathologica
IF9.3
err2026-04-25
err0
errOAAI
errRamin Rahmanzade; Leonille Schweizer; Simone Schmid; Tereza Lausová; Gianluca Sigismondo; Mozhgan Esmaeili Benvidi; Rushda Patel; Aras Fuat Kaan; Rouzbeh Banan; David Reuss; Natalie Jäger; Marie-Theresa Forster; Viktoria Zeller; Patricia Kohlhof-Meinecke; Annette Fisseler-Eckhoff; Barbara Carl; Patrick N. Harter; Katrin Lamszus; Ulrich Schüller; Michal Zapotocky; Till Acker; C. O. Hanemann; Jens Schittenhelm; Eva Brack; Uta Flucke; Gunhild Mechtersheimer; Luca Bertero; Christine Haberler; David Capper; Andreas von Deimling; Philipp Sievers; Felix Sahm
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Hypoxia or tobacco-smoke exposure induce region-specific microvascular remodeling in the brain缺氧或烟草烟雾暴露诱导脑内区域性微血管重塑
errScientific Reports
IF3.9
err2026-04-17
err0
errOAAI
errNazli Salik Demirtas; Edma Loku; Yasmine Porschen; Julia Schäffer; Cheng-Yu Wu; Christoph Rummel; Natascha Sommer; Stefan Hadzic; Norbert Weissmann; Till Acker; Attila Németh
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err收藏
Loss of global DNA hypermethylation is prognostic in IDH-mutant and 1p/19q-codeleted oligodendrogliomas全球DNA高甲基化丢失是IDH突变型和1p/19q共缺失型少突胶质细胞瘤的预后指标。
errActa Neuropathologica
IF9.3
err2025-11-26
err0
errOAAI
errFelix E. Hinz; Dennis Friedel; Franziska M. Ippen; Martin Sill; Andrey Korshunov; Leonille Schweizer; Daniel Schrimpf; Kirsten Göbel; Lukas S. Friedrich; Fuat K. Aras; Henri Bogumil; Rouzbeh Banan; Hildegard Dohmen; Till Acker; Sebastian Brandner; Simone Schmid; David Capper; Niklas Grassl; Henning B. Boldt; Pieter Wesseling; Sybren L. N. Maas; Juan P. Garces Martinez; Christine Stadelmann; Guido Reifenberger; Thomas Stehle; Alonso Barrantes-Freer; Tareq A. Juratli; Stefan Pusch; Daniel Haag; David E. Reuss; Christel Herold-Mende; Sandro Krieg; Wolfgang Wick; Nima Etminan; Michael Platten; Stefan M. Pfister; David T. W. Jones; Felix Sahm; Andreas von Deimling; Abigail K. Suwala
err分享
err收藏
Hetairos enables AI-based histopathological classification of CNS tumoursHetairos 实现了基于 AI 的 CNS 肿瘤组织病理学分类
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errPatel, Areeba; Jin, Darui; Shmatko, Artem; Rahmanzade, Ramin; Friederich, Lukas; Schrimpf, Daniel; Sievers, Philipp; Alhalabi, Obada; Rutz, Samuel; Suwala, Abigail; Sturm, Dominik; Wesseling, Pieter; Woehrer, Adelheid; Hou, Yanghao; Costa, Felipe D'almeida; Ille, Sebastian; Al-Hussaini, Maysa; Bertero, Luca; Schweizer, Leonille; Wiestler, Benedikt; Snuderl, Matija; Pfister, Stefan M.; Jones, David T. W.; Varlet, Pascale; Tauziede-Espariat, Arnault; Acker, Till; Brandner, Sebastian; Krieg, Sandro; Wick, Wolfgang; Bai, Xiangzhi; Von Deimling, Andreas; Gerstung, Moritz; Sahm, Felix
err分享
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MACHINE LEARNING AND MULTI-OMIC ANALYSIS IDENTIFY A MICROENVIRONMENT-DRIVEN MENINGIOMA RISK CONTINUUM UNDERLYING MOLECULAR CLASSIFICATIONS机器学习和多组学分析识别出一种由微环境驱动的、与分子分类相关的脑膜瘤风险连续体
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errMaas, Sybren; Tang, Yiheng; Stutheit-Zhao, Eric; Rahmanzade, Ramin; Hielscher, Thomas; Zettl, Ferdinand; Benfatto, Salvatore; Calafato, Domenico; Sill, Martin; Benotmane, Jasim Kada; Yabo, Yahaya; Peyre, Matthieu; Sankowski, Roman; Okonechnikov, Konstantin; Sievers, Philip; Patel, Areeba; Reuss, David; Hanemann, Oliver; Lamszus, Katrin; Etminan, Nima; Unterberg, Andreas; Mawrin, Christian; Grossmann, Rachel; Ram, Zvi; Ratliff, Miriam; Neidert, Marian; Bos, Eelke; Prinz, Marco; Weller, Michael; Acker, Till; Hartmann, Felix; Preusser, Matthias; Tabatabai, Ghazaleh; Herold-Mende, Christel; Krieg, Sandro; Jones, David; Pfister, Stefan; Wick, Wolfgang; Kalamarides, Michel; Von Deimling, Andreas; Heiland, Dieter Henrik; Hovestadt, Volker; Gerstung, Moritz; Schlesner, Matthias; Sahm, Felix
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AI-BASED HISTOPATHOLOGICAL CLASSIFICATION OF CENTRAL NERVOUS SYSTEM TUMOURS基于人工智能的中央神经系统肿瘤组织病理学分类
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errJin, D.; Shmatko, A.; Patel, A.; Rahmanzade, R.; Friedrich, L.; Schrimpf, D.; Sievers, P.; Alhalabi, O.; Rutz, S. P.; Suwala, A. K.; Sturm, D.; Wesseling, P.; Woehrer, A.; Hou, Y.; D'almeida Costa, F.; Ille, S.; Al-Hussaini, M.; Bertero, L.; Schweizer, L.; Wiestler, B.; Snuderl, M.; Pfister, S. M.; Jones, D. T. W.; Varlet, P.; Tauziede-Espariat, A.; Acker, T.; Brandner, S.; Krieg, S. M.; Wick, W.; Bai, X.; von Deimling, A.; Gerstung, M.; Sahm, F.
err分享
err收藏
Developing an advanced risk stratification model for pediatric intracranial ependymoma based on the prospective trial E-HIT2000 and subsequent registries基于前瞻性试验E-HIT2000及后续登记研究的儿童颅内室管膜瘤高级风险分层模型开发
errNeuro-Oncology
IF13.4
err2025-09-30
err0
PREAI
errKatja von Hoff; Denise Obrecht-Sturm; David R Ghasemi; Janna Wenning; Martin Mynarek; Nicolas U Gerber; Martin Benesch; Björn O Juhnke; Brigitte Bison; Monika Warmuth-Metz; Beate Timmermann; Andreas Faldum; Stephan Tippelt; Gudrun Fleischhack; Michael Grotzer; Pablo Hernáiz Driever; Andreas Beilken; Martin Ebinger; Norbert Graf; Michael C Frühwald; Irene Schmid; Irene Slavc; Arend Koch; Markus Bergmann; Christian Hagel; Roland Coras; Ingmar Blümcke; Guido Reifenberger; Jörg Felsberg; Kathy Keyvani; Patrick N Harter; Marco Prinz; Ori Staszewski; Till Acker; Christine Stadelmann-Nessler; Christian Hartmann; Andreas von Deimling; Clemens Sommer; Martin Hasselblatt; Markus J Riemenschneider; Camelia-Maria Monoranu; Elisabeth Rushing; Christine Haberler; Marcel Kool; Martin Sill; Stefan M Pfister; Ulrich Schüller; Torsten Pietsch; Rolf D Kortmann; Robert Kwiecien; Hendrik Witt; Kristian W Pajtler; Stefan Rutkowski; the German, Austrian and Swiss HIT-Network
err分享
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Professor Helmut Acker (1939–2025)赫尔穆特·阿克尔教授（1939–2025）
errPflügers Archiv - European Journal of Physiology
IF0
err2025-09-19
err0
errOAAI
errTill Acker; Joachim Fandrey; Jörgen Carlsson
err分享
err收藏
Molecular signatures define BAP1-altered meningioma as a distinct CNS tumor with deregulation of Polycomb repressive complex target genes分子特征将BAP1-altered脑膜瘤定义为一种具有Polycomb抑制复合物靶基因失调的特定中枢神经系统肿瘤
errNEURO-ONCOLOGY
IF13.4
err2025-06-01
err4
PREAI
errSievers, Philipp; Arora, Sonali; Hielscher, Thomas; Savran, Dilan; Schrimpf, Daniel; Banan, Rouzbeh; Vonhoeren, David; Pusch, Stefan; Sill, Martin; Appay, Romain; Wirsching, Hans-Georg; Hortobagyi, Tibor; Dohmen, Hildegard; Acker, Till; Kohlhof-Meinecke, Patricia; Schweizer, Leonille; Wefers, Annika K.; Harter, Patrick N.; Hartmann, Christian; Beschorner, Rudi; Schittenhelm, Jens; Behling, Felix; Tabatabai, Ghazaleh; Mawrin, Christian; Snuderl, Matija; Maas, Sybren L. N.; Wesseling, Pieter; Brandner, Sebastian; Korshunov, Andrey; Ratliff, Miriam; Krieg, Sandro M.; Wick, Wolfgang; Jones, David T. W.; Pfister, Stefan M.; Holland, Eric C.; von Deimling, Andreas; Szulzewsky, Frank; Sahm, Felix
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err收藏
Vascular FLRT2 regulates venous-mediated angiogenic expansion and CNS barriergenesis
errNATURE COMMUNICATIONS
IF15.7
err2024-11-29
err0
errOAAI
errLlao-Cid, C.; Peguera, B.; Kobialka, P.; Decker, L.; Vogenstahl, J.; Alivodej, N.; Srivastava, S.; Jin, J.; Kirchmaier, B. C.; Milla, C.; Schlierbach, H.; Schaenzer, A.; Acker, T.; Segarra, M.; Acker-Palmer, A.
err分享
err收藏
IMPROVED OUTCOME PREDICTION AND GRADING OF THE NOVEL TUMOUR TYPE GLIOMATOSIS CEREBRI-LIKE GLIOMA, IDH-WILDTYPE (GCLG, IDH-WT)
errNEURO-ONCOLOGY
IF13.4
err2024-10-17
err0
PREAI
errMuenzberg, M.; Muench, A.; Dive, I; Wenger-Alakmeh, K.; Forster, M.; Costa, F.; Dehais, C.; Bielle, F.; Kuzman, P.; Mueller, W. C.; Umathum, V; Acker, T.; Beschorner, R.; von Baumgarten, L.; Harter, P. N.; Thomas, C.; Misch, M.; Capper, D.; Wefers, A. K.; Neumann, J. E.; Schueller, U.; Czabanka, M.; Steinbach, J. P.; Plate, K. H.; Brandner, S.; Schweizer, L.
err分享
err收藏
Loss over 5% of chromosome 1p is a clinically relevant and applicable cut-off for increased risk of recurrence in meningioma
errACTA NEUROPATHOLOGICA
IF9.3
err2024-08-08
err0
errOAAI
errMaas, Sybren L. N.; Hielscher, Thomas; Sievers, Philipp; Hovestadt, Volker; Suwala, Abigail K.; Acker, Till; Weller, Michael; Preusser, Matthias; Herold-Mende, Christel; Wick, Wolfgang; von Deimling, Andreas; Berghaus, Natalie; Sahm, Felix
err分享
err收藏
Survival probability of epigenetically defined IDH-wild-type glioblastoma without necrosis or vascular proliferation
errNEURO-ONCOLOGY ADVANCES
IF4.1
err2024-08-02
err0
errOAAI
errHarter, Patrick N.; Weber, Katharina J.; Ricklefs, Franz L.; Drexler, Richard; Schueller, Ulrich; Hack, Marcel; Hanke, Tim; Dohmen, Hildegard; Acker, Till; von Deimling, Andreas; Hasselblatt, Martin; Dive, Iris; Unger, Kristian; Steinbach, Joachim P.; Capper, David; Ronellenfitsch, Michael W.
err分享
err收藏
Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations
errACTA NEUROPATHOLOGICA
IF9.3
err2024-07-18
err1
errOAAI
errSievers, Philipp; Bielle, Franck; Goebel, Kirsten; Schrimpf, Daniel; Nichelli, Lucia; Mathon, Bertrand; Appay, Romain; Boldt, Henning B.; Dohmen, Hildegard; Selignow, Carmen; Acker, Till; Vicha, Ales; Martinetto, Horacio; Schweizer, Leonille; Schueller, Ulrich; Brandner, Sebastian; Wesseling, Pieter; Schmid, Simone; Capper, David; Abdullaev, Zied; Aldape, Kenneth; Korshunov, Andrey; Krieg, Sandro M.; Wick, Wolfgang; Pfister, Stefan M.; von Deimling, Andreas; Reuss, David E.; Jones, David T. W.; Sahm, Felix
err分享
err收藏
MOLECULAR MARKERS AND PREDICTORS OF OUTCOME FOR PAEDIATRIC INTRACRANIAL EPENDYMOMA IN THE PROSPECTIVE, MULTICENTRE E-HIT2000 TRIAL AND SUBSEQUENT HIT-REGISTRIES: A POOLED ANALYSIS OF 244 PATIENTS在前瞻性，多中心E-HIT2000试验和随后的HIT注册研究中，儿童颅内室管膜瘤的分子标志物和预后预测因素: 对244例患者的汇总分析
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errGhasemi, David R.; von Hoff, Katja; Obrecht-Sturm, Denise; Wenning, Janna; Mynarek, Martin; Gerber, Nicolas U.; Benesch, Martin; Juhnke, Bjoern O.; Bison, Brigitte; Warmuth-Metz, Monika; Timmermann, Beate; Faldum, Andreas; Fleischhack, Gudrun; Grotzer, Michael; Driever, Pablo Hernaiz; Beilken, Andreas; Ebinger, Martin; Graf, Norbert; Fruehwald, Michael; Schmid, Irene; Koch, Arend; Bergmann, Markus; Hagel, Christian; Coras, Roland; Bluemcke, Ingmar; Reifenberger, Guido; Felsberg, Joerg; Keyvani, Kathy; Harter, Patrick N.; Prinz, Marco; Staszewski, Ori; Acker, Till; Brueck, Wolfgang; Hartmann, Christian; von Deimling, Andreas; Sommer, Clemens; Hasselblatt, Martin; Riemenschneider, Markus J.; Monoranu, Camelia-Maria; Rushing, Elisabeth; Kool, Marcel; Pfister, Stefan M.; Schueller, Ulrich; Pietsch, Torsten; Kortmann, Rolf D.; Kwiecien, Robert; Witt, Hendrik; Pajtler, Kristian W.; Rutkowski, Stefan
err分享
err收藏
DistSNE: Distributed computing and online visualization of DNA methylation-based central nervous system tumor classification
errBRAIN PATHOLOGY
IF6.2
err2023-11-27
err1
errOAAI
errSchmid, Kai; Sehring, Jannik; Nemeth, Attila; Harter, Patrick N.; Weber, Katharina J.; Vengadeswaran, Abishaa; Storf, Holger; Seidemann, Christian; Karki, Kapil; Fischer, Patrick; Dohmen, Hildegard; Selignow, Carmen; von Deimling, Andreas; Grau, Stefan; Schroeder, Uwe; Plate, Karl H.; Stein, Marco; Uhl, Eberhard; Acker, Till; Amsel, Daniel
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err收藏
Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.H137Lfs*4)
errBRAIN PATHOLOGY
IF6.2
err2023-06-02
err1
errOAAI
errUmathum, Vincent; Weber, Axel; Amsel, Daniel; Alexopoulos, Ioannis; Becker, Christina; Roth, Angela; Guenther, Andreas; Selignow, Carmen; Ritschel, Nadja; Nishimura, Anna; Schaiter, Alexander; Nemeth, Attila; van der Ven, Peter F. M.; Acker, Till; Schaenzer, Anne
err分享
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