未登录 Soluble CD27 is an intrathecal biomarker of T-cell-mediated lesion activity in multiple sclerosis 可溶性CD27是多发性硬化症中T细胞介导的病变活性的鞘内生物标志物 Cencioni, Maria T.; Magliozzi, Roberta; Palmisano, Ilaria; Suwan, Keittisak; Mensi, Antonella; Fuentes-Font, Laura; Villar, Luisa M.; Fernandez-Velasco, Jose I.; Migallon, Noelia Villarrubia; Costa-Frossard, Lucienne; Monreal, Enric; Ali, Rehiana; Romozzi, Marina; Mazarakis, Nicholas; Reynolds, Richard; Nicholas, Richard; Muraro, Paolo A. 分享 收藏
Lymphotoxin-alpha expression in the meninges causes lymphoid tissue formation and neurodegeneration 淋巴毒素-α 在脑膜中的表达导致淋巴组织形成和神经变性 Bates, Rachel E. James; Browne, Eleanor; Schalks, Renee; Jacobs, Heather; Tan, Li; Parekh, Puja; Magliozzi, Roberta; Calabrese, Massimiliano; Mazarakis, Nicholas D.; Reynolds, Richard 分享 收藏
Not Just Loss-of-Function Variations Identification of a Hypermorphic Variant in a Patient With a CDKL5 Missense Substitution Frasca, Angelisa; Pavlidou, Efterpi; Bizzotto, Matteo; Gao, Yunan; Balestra, Dario; Pinotti, Mirko; Dahl, Hans Atli; Mazarakis, Nicholas D.; Landsberger, Nicoletta; Kinali, Maria 分享 收藏
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Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration 多发性硬化症的脑膜炎症诱导皮质小胶质细胞的表型变化，与神经变性有差异 van Olst, Ynn; Rodriguez-Mogeda, Carla; Picon, Carmen; Kiljan, Svenja; James, Rachel E.; Kamermans, Alwin; van der Pol, Susanne M. A.; Knoop, Lydian; Michailidou, Iliana; Drost, Evelien; Franssen, Marc; Schenk, Geert J.; Geurts, Jeroen J. G.; Amor, Sandra; Mazarakis, Nicholas D.; van Horssen, Jack; de Vries, Helga E.; Reynolds, Richard; Witte, Maarten E. 分享 收藏
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Gene replacement ameliorates deficits in mouse and human models of cyclin-dependent kinase-like 5 disorder Gao, Yunan; Irvine, Elaine E.; Eleftheriadou, Ioanna; Naranjo, Carlos Jimenez; Hearn-Yeates, Francesca; Bosch, Leontien; Glegola, Justyna A.; Murdoch, Leah; Czerniak, Aleksandra; Meloni, Ilaria; Renieri, Alessandra; Kinali, Maria; Mazarakis, Nicholas D. 分享 收藏
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PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer's disease model Katsouri, Loukia; Lim, Yau M.; Blondrath, Katrin; Eleftheriadou, Ioanna; Lombardero, Laura; Birch, Amy M.; Mirzaei, Nazanin; Irvine, Elaine E.; Mazarakis, Nicholas D.; Sastre, Magdalena 分享 收藏
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IκBα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention Pazarentzos, Evangelos; Mahul-Mellier, Anne-Laure; Datler, Christoph; Chaisaklert, Wanwisa; Hwang, Ming-Shih; Kroon, Jan; Qize, Ding; Osborne, Foy; Al-Rubaish, Abdullah; Al-Ali, Amein; Mazarakis, Nicholas D.; Aboagye, Eric O.; Grimm, Stefan 分享 收藏
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Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial 基于慢病毒载体的帕金森病基因治疗ProSavin的长期安全性和耐受性: 剂量递增，开放标签，1/2期试验 Palfi, Stephane; Gurruchaga, Jean Marc; Ralph, G. Scott; Lepetit, Helene; Lavisse, Sonia; Buttery, Philip C.; Watts, Colin; Miskin, James; Kelleher, Michelle; Deeley, Sarah; Iwamuro, Hirokazu; Lefaucheur, Jean Pascal; Thiriez, Claire; Fenelon, Gilles; Lucas, Cherry; Brugieres, Pierre; Gabriel, Inanna; Abhay, Kou; Drouot, Xavier; Tani, Naoki; Kas, Aurelie; Ghaleh, Bijan; Le Corvoisier, Philippe; Dolphin, Patrice; Breen, David P.; Mason, Sarah; Guzman, Natalie Valle; Mazarakis, Nicholas D.; Radcliffe, Pippa A.; Harrop, Richard; Kingsman, Susan M.; Rascol, Olivier; Naylor, Stuart; Barker, Roger A.; Hantraye, Philippe; Remy, Philippe; Cesaro, Pierre; Mitrophanous, Kyriacos A. 分享 收藏
Dose-dependent Neuroprotection of VEGF165 in Huntington's Disease Striatum Ellison, Stuart M.; Trabalza, Antonio; Tisato, Veronica; Pazarentzos, Evangelos; Lee, Shirley; Papadaki, Vasiliki; Goniotaki, Despoina; Morgan, Sarah; Mirzaei, Nazanin; Mazarakis, Nicholas D. 分享 收藏
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Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase Mitchell, John; Paul, Praveen; Chen, Han-Jou; Morris, Alex; Payling, Miles; Falchi, Mario; Habgood, James; Panoutsou, Stefania; Winkler, Sabine; Tisato, Veronica; Hajitou, Amin; Smith, Bradley; Vance, Caroline; Shaw, Christopher; Mazarakis, Nicholas D.; de Belleroche, Jacqueline 分享 收藏
Dopamine Gene Therapy for Parkinson's Disease in a Nonhuman Primate Without Associated Dyskinesia Jarraya, Bechir; Boulet, Sabrina; Ralph, G. Scott; Jan, Caroline; Bonvento, Gilles; Azzouz, Mimoun; Miskin, James E.; Shin, Masahiro; Delzescaux, Thierry; Drouot, Xavier; Herard, Anne-Sophie; Day, Denise M.; Brouillet, Emmanuel; Kingsman, Susan M.; Hantraye, Philippe; Mitrophanous, Kyriacos A.; Mazarakis, Nicholas D.; Palfi, Stephane 分享 收藏
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