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周生 封面图

周生 (Sheng Zhou)

St Jude Children's Research Hospital副教授
H指数:39
被引数:7,915

个人简介

副教授，博士。2002年毕业于四川农业大学动物医学院预防兽医专业，获博士学位；1999年毕业于四川农业大学动物医学院预防兽医专业，获硕士学位；1995年毕业于浙江大学动物科技学院兽医专业，获学士学位。

教育背景

  • 2002.12

    四川农业大学 博士 预防兽医专业

  • 1999.12

    四川农业大学 硕士 预防兽医专业

  • 1995.12

    浙江大学 本科 兽医专业

工作经历

暂无内容

荣誉奖项

暂无内容

Targeting Regnase-1 in B7-H3-CAR T cells reprograms the tumor microenvironment and enhances antitumor efficacy for osteosarcoma

靶向B7-H3-CAR T细胞中的Regnase-1重编程肿瘤微环境并增强对骨肉瘤的抗肿瘤功效

Cell Reports Medicine
IF10.6
2026-09-010
PRE
Adeshakin, Adeleye O.; Shi, Hao; Perry, S. Scott; Sheppard, Heather; Nguyen, Phuong; Sun, Xiang; Zhou, Peipei; Metais, Jean-Yves; Cunningham, Trevor; Anil, K. C.; Tian, Liqing; Peche, Vivek; Prater, Mollie S.; Langfitt, Deanna M.; O'Reilly, Carla; Park, Jeoungeun J.; Chabot, Ashley; Zhou, Sheng; Matsubara, Azusa; Lee, GaHyun; Tsai, Shengdar Q.; Pruett-Miller, Shondra M.; Talbot, Lindsay J.; Yustein, Jason T.; Krenciute, Giedre; DeRenzo, Christopher; Chi, Hongbo; Gottschalk, Stephen
SUCCESSFUL AUTOLOGOUS T CELL APHERESIS IN PEDIATRIC PATIENTS WITH HEMATOLOGIC MALIGNANCIES, SOLID TUMORS, AND BRAIN TUMORS

在患有血液恶性肿瘤、实体瘤和脑肿瘤的儿科患者中成功进行自体T细胞单采术

Cytotherapy
IF3.2
2026-05-110
OAAI
Devin Murphy; Yu Bi; Aysha Patel; Ying Li; Yan Zheng; Leigh Poston; Salem Akel; Chris Kilpatrick; Timothy Lockey; Sheng Zhou; Kelsey C. Bertrand; Christopher DeRenzo; Swati Naik; Akshay Sharma; Aimee C. Talleur; M. Paulina Velasquez; Brandon M. Triplett; Stephen Gottschalk; Subodh Selukar; Rebecca Epperly
Increased capacity for expansion, not persistence, improves preclinical B7-H3 targeted CAR T cell therapy against aggressive Group 3 medulloblastomas

扩增能力而非持久性增强，可改善针对侵袭性Group 3髓母细胞瘤的B7-H3靶向CAR T细胞疗法的前临床效果

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Ward, Meghan; Meehl, Michaela; Senaoui, Linda; Park, Jeoungeun John; Ibanez-Vega, Jorge; Dovidonyte, Rugile; Kujur, Weshely; Zhou, Sheng; Bertrand, Kelsey; Derenzo, Christopher; Gottschalk, Stephen; Roussel, Martine; Youngblood, Benjamin; Chi, Hongbo; Krenciute, Giedre
Preclinical development of lentiviral vector gene therapy for Diamond-Blackfan anemia syndrome

lentiviral vector gene therapy for Diamond-Blackfan anemia syndrome的preclinical development

Molecular Therapy
IF12
2024-12-120
OA
Senthil Velan Bhoopalan; Thiyagaraj Mayuranathan; Nana Liu; Kalin Mayberry; Yu Yao; Jingjing Zhang; Jean-Yves Métais; Koon-Kiu Yan; Robert E. Throm; Steven R. Ellis; Yan Ju; Lei Han; Shruthi Suryaprakash; Lance E. Palmer; Sheng Zhou; Jiyang Yu; Yong Cheng; Jonathan S. Yen; Stephen Gottschalk; Mitchell J. Weiss
Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34+cell therapy to induce fetal hemoglobin for sickle cell disease

新型Cas9基因组编辑的自体CD34细胞疗法诱导胎儿血红蛋白治疗镰状细胞病的开发和IND支持研究

MOLECULAR THERAPY
IF12
2024-10-010
OAAI
Katta, Varun; O'Keefe, Kiera; Li, Yichao; Mayuranathan, Thiyagaraj; Lazzarotto, Cicera R.; Wood, Rachael K.; Levine, Rachel M.; Powers, Alicia; Mayberry, Kalin; Manquen, Garret; Yao, Yu; Zhang, Jingjing; Jang, Yoonjeong; Nimmagadda, Nikitha; Dempsey, Erin A.; Lee, GaHyun; Uchida, Naoya; Cheng, Yong; Fazio, Frank; Lockey, Tim; Meagher, Mike; Sharma, Akshay; Tisdale, John F.; Zhou, Sheng; Yen, Jonathan S.; Weiss, Mitchell J.; Tsai, Shengdar Q.
Integrome signatures of lentiviral gene therapy for SCID-X1 patients
SCIENCE ADVANCES
IF12.5
2023-10-060
OAAI
Yan, Koon-Kiu; Condori, Jose; Ma, Zhijun; Metais, Jean-Yves; Ju, Bensheng; Ding, Liang; Dhungana, Yogesh; Palmer, Lance E.; Langfitt, Deanna M.; Ferrara, Francesca; Throm, Robert; Shi, Hao; Risch, Isabel; Bhatara, Sheetal; Shaner, Bridget; Lockey, Timothy D.; Talleur, Aimee C.; Easton, John; Meagher, Michael M.; Puck, Jennifer M.; Cowan, Morton J.; Zhou, Sheng; Mamcarz, Ewelina; Gottschalk, Stephen; Yu, Jiyang
Preferential expansion of CD8+CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL

输注后CD8 CD19-CAR T细胞的优先扩增以及疾病负担对小儿b-all结局的作用

BLOOD ADVANCES
IF7.1
2022-11-0824
OAAI
Talleur, Aimee C.; Qudeimat, Amr; Metais, Jean-Yves; Langfitt, Deanna; Mamcarz, Ewelina; Crawford, Jeremy Chase; Huang, Sujuan; Cheng, Cheng; Hurley, Caitlin; Madden, Renee; Sharma, Akshay; Suliman, Ali; Srinivasan, Ashok; Velasquez, M. Paulina; Obeng, Esther A.; Willis, Catherine; Akel, Salem; Karol, Seth E.; Inaba, Hiroto; Bragg, Allison; Zheng, Wenting; Zhou, Sheng M.; Schell, Sarah; Tuggle-Brown, Macal; Cullins, David; Patil, Sagar L.; Li, Ying; Thomas, Paul G.; Zebley, Caitlin; Youngblood, Benjamin; Pui, Ching-Hon; Lockey, Timothy; Geiger, Terrence L.; Meagher, Michael M.; Triplett, Brandon M.; Gottschalk, Stephen
Lentivector cryptic splicing mediates increase in CD34+clones expressing truncated HMGA2 in human X-linked severe combined immunodeficiency
NATURE COMMUNICATIONS
IF15.7
2022-06-2821
OAAI
De Ravin, Suk See; Liu, Siyuan; Sweeney, Colin L.; Brault, Julie; Whiting-Theobald, Narda; Ma, Michelle; Liu, Taylor; Choi, Uimook; Lee, Janet; O'Brien, Sandra Anaya; Quackenbush, Priscilla; Estwick, Tyra; Karra, Anita; Docking, Ethan; Kwatemaa, Nana; Guo, Shuang; Su, Ling; Sun, Zhonghe; Zhou, Sheng; Puck, Jennifer; Cowan, Morton J.; Notarangelo, Luigi D.; Kang, Elizabeth; Malech, Harry L.; Wu, Xiaolin
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity

在CAR T细胞中删除DNMT3A可防止耗竭并增强抗肿瘤活性

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-11-17180
OA
Prinzing, Brooke; Zebley, Caitlin C.; Petersen, Christopher T.; Fan, Yiping; Anido, Alejandro Allo; Yi, Zhongzhen; Phuong Nguyen; Houke, Haley; Bell, Matthew; Haydar, Dalia; Brown, Charmaine; Boi, Shannon K.; Alli, Shanta; Crawford, Jeremy Chase; Riberdy, Janice M.; Park, Jeoungeun J.; Zhou, Sheng; Velasquez, Mireya Paulina; DeRenzo, Chris; Lazzarotto, Cicera R.; Tsai, Shengdar Q.; Vogel, Peter; Pruett-Miller, Shondra M.; Langfitt, Deanna M.; Gottschalk, Stephen; Youngblood, Ben; Krenciute, Giedre
Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1

慢病毒基因治疗联合低剂量白消安治疗婴幼儿SCID-X1

NEW ENGLAND JOURNAL OF MEDICINE
IF78.5
2019-04-18181
OAAI
Mamcarz, Ewelina; Zhou, Sheng; Lockey, Timothy; Abdelsamed, Hossam; Cross, Shane J.; Kang, Guolian; Ma, Zhijun; Condori, Jose; Dowdy, Jola; Triplett, Brandon; Li, Chen; Maron, Gabriela; Aldave Becerra, Juan C.; Church, Joseph A.; Dokmeci, Elif; Love, James T.; da Matta Ain, Ana C.; van der Watt, Hedi; Tang, Xing; Janssen, William; Ryu, Byoung Y.; De Ravin, Suk See; Weiss, Mitchell J.; Youngblood, Benjamin; Long-Boyle, Janel R.; Gottschalk, Stephen; Meagher, Michael M.; Malech, Harry L.; Puck, Jennifer M.; Cowan, Morton J.; Sorrentino, Brian P.

研究方向

动物源冠状病毒的分子流行病学及其致病机制研究新型兽用生物制品研发的关键技术研究鸡传染性支气管炎重组灭活疫苗研究鸡传染性支气管炎病毒胚化致弱株毒力减弱的分子机制研究冠状病毒外源基因稳定性猪圆环病毒、猪肺炎支原体二联灭活疫苗研制鸡传染性支气管炎病毒载体表达异源蛋白
B
Brian P. Sorrentino
H 指数:51论文数:205被引数:1.2万
S
Stephen Gottschalk
H 指数:77论文数:695被引数:2.1万
Z
Zhijun Ma
H 指数:22论文数:59被引数:2,109
T
Timothy Lockey
H 指数:26论文数:97被引数:2,467
R
Robert E. Throm
H 指数:14论文数:31被引数:1,006
C
Christopher DeRenzo
H 指数:18论文数:117被引数:1,511
X
Xinhua Liu
H 指数:21论文数:172被引数:1,817
余
余宏杰
H 指数:92论文数:842被引数:4.8万
G
Giedre Krenciute
H 指数:27论文数:233被引数:4,151
李孟森 封面图
李孟森
H 指数:29论文数:96被引数:2,620