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A phase I/II, open-label study of the novel checkpoint IGSF8 inhibitor GV20-0251 in patients with advanced solid tumors 一项关于新型检查点IGSF8抑制剂GV20-0251的I/II期、开放标签研究，用于治疗晚期实体瘤患者 Wentzel, K.; Peguero, J.; Kummar, S.; Lorusso, P.; Mehnert, J. M.; Spira, A. I.; Naing, A.; Hamid, O.; Mehmi, I.; Benhadji, K.; Alland, L.; Hu, X.; Xiao, H.; Bao, X.; Chen, J.; Gong, Y.; Liu, X. S. 分享 收藏
Plain language summary of the FOENIX-CCA2 study: futibatinib for people with advanced bile duct cancer FOENIX-CCA2研究的简明语言摘要: futibatinib用于晚期胆管癌患者 Goyal, Lipika; Meric-Bernstam, Funda; Hollebecque, Antoine; Valle, Juan W.; Morizane, Chigusa; Karasic, Thomas B.; Abrams, Thomas A.; Furuse, Junji; Kelley, Robin Katie; Cassier, Philippe A.; Klumpen, Heinz-Josef; Chang, Heung-Moon; Chen, Li-Tzong; Tabernero, Josep; Oh, Do-Youn; Mahipal, Amit; Moehler, Markus; Komatsu, Yoshito; Ahn, Daniel H.; Epstein, Robert S.; Halim, Abdel-Baset; Wacheck, Volker; He, Yaohua; Liu, Mei; Benhadji, Karim A.; Bridgewater, John A. 分享 收藏
IGSF8 is an innate immune checkpoint and cancer immunotherapy target Benhadji, K.; Li, Y.; Wu, X.; Liu, H.; Xiao, X.; Liu, H.; Ding, Q.; Xie, B.; Sheng, C.; Zheng, R.; Yu, Q.; Hu, X.; Liu, X. S.; Xiao, T. 分享 收藏
A phase Ib/II study of galunisertib in combination with nivolumab in solid tumors and non-small cell lung cancer Nadal, Ernest; Saleh, Mansoor; Aix, Santiago Ponce; Ochoa-de-Olza, Maria; Patel, Sandip Pravin; Antonia, Scott; Zhao, Yumin; Gueorguieva, Ivelina; Man, Michael; Estrem, Shawn T.; Liu, Jiangang; Avsar, Emin; Lin, Wen Hong; Benhadji, Karim A.; Gandhi, Leena; Guba, Susan C.; Diaz, Inmaculada Ales 分享 收藏
Trifluridine-Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer 三氟尿苷-替匹拉西和贝伐单抗治疗难治性转移性结直肠癌 Prager, Gerald W.; Taieb, Julien; Fakih, Marwan; Ciardiello, Fortunato; Van Cutsem, Eric; Elez, Elena; Cruz, Felipe M.; Wyrwicz, Lucjan; Stroyakovskiy, Daniil; Papai, Zsuzsanna; Poureau, Pierre-Guillaume; Liposits, Gabor; Cremolini, Chiara; Bondarenko, Igor; Modest, Dominik P.; Benhadji, Karim A.; Amellal, Nadia; Leger, Catherine; Vidot, Loick; Tabernero, Josep 分享 收藏
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Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma Futibatinib治疗FGFR2-Rearranged肝内胆管癌 Goyal, Lipika; Meric-Bernstam, Funda; Hollebecque, Antoine; Valle, Juan W.; Morizane, Chigusa; Karasic, Thomas B.; Abrams, Thomas A.; Furuse, Junji; Kelley, Robin K.; Cassier, Philippe A.; Kluempen, Heinz-Josef; Chang, Heung-Moon; Chen, Li-Tzong; Tabernero, Josep; Oh, Do-Youn; Mahipal, Amit; Moehler, Markus; Mitchell, Edith P.; Komatsu, Yoshito; Masuda, Kunihiro; Ahn, Daniel; Epstein, Robert S.; Halim, Abdel-Baset; Fu, Yao; Salimi, Tehseen; Wacheck, Volker; He, Yaohua; Liu, Mei; Benhadji, Karim A.; Bridgewater, John A. 分享 收藏
Pooled safety analysis from phase III studies of trifluridine/tipiracil in patients with metastatic gastric or gastroesophageal junction cancer and metastatic colorectal cancer Van Cutsem, E.; Hochster, H.; Shitara, K.; Mayer, R.; Ohtsu, A.; Falcone, A.; Yoshino, T.; Doi, T.; Ilson, D. H.; Arkenau, H-T; George, B.; Benhadji, K. A.; Makris, L.; Tabernero, J. 分享 收藏
Dose escalation of TAS-117 in patients with advanced solid tumors Rodon, J.; Arkenau, H-T.; Funchain, P.; Hervieu, A.; Gao, L.; Liu, M.; Halim, A.; Mina, M.; Takahashi, O.; Benhadji, K.; Delaloge, S. 分享 收藏
A phase II study of TAS-117 in patients with advanced solid tumors harboring germline PTEN-inactivating mutations Rodon, Jordi; Funchain, Pauline; Laetsch, Theodore W.; Arkenau, Hendrik-Tobias; Hervieu, Alice; Singer, Christian F.; Murciano-Goroff, Yonina R.; Chawla, Sant P.; Anthony, Kristin; Yamamiya, Ikuo; Liu, Mei; Halim, Abdel-Baset; Benhadji, Karim A.; Takahashi, Osamu; Delaloge, Suzette 分享 收藏
Efficacy and safety of trifluridine/tipiracil in older and younger patients with metastatic gastric or gastroesophageal junction cancer: subgroup analysis of a randomized phase 3 study (TAGS) Shitara, Kohei; Doi, Toshihiko; Hosaka, Hisashi; Thuss-Patience, Peter; Santoro, Armando; Longo, Federico; Ozyilkan, Ozgur; Cicin, Irfan; Park, David; Zaanan, Aziz; Pericay, Carles; Ozguroglu, Mustafa; Alsina, Maria; Makris, Lukas; Benhadji, Karim A.; Ilson, David H. 分享 收藏
Futibatinib, an Irreversible FGFR1-4 Inhibitor, in Patients with Advanced Solid Tumors Harboring FGF/FGFR Aberrations: A Phase I Dose-Expansion Study Meric-Bernstam, Funda; Bahleda, Rastislav; Hierro, Cinta; Sanson, Marc; Bridgewater, John; Arkenau, Hendrik-Tobias; Tran, Ben; Kelley, Robin Kate; Park, Joon Oh; Javle, Milind; He, Yaohua; Benhadji, Karim A.; Goyal, Lipika 分享 收藏
A phase II study of TAS-117 in patients with advanced solid tumors harboring germline PTEN inactivating mutations Rodon, J.; Funchain, P.; Laetsch, T. W.; Singer, C. F.; Arkenau, H-T.; Chawla, S. P.; Hervieu, A.; Yamamiya, I.; Liu, M.; Benhadji, K. A.; Takahashi, O.; Delaloge, S. 分享 收藏
A Phase I Study of an IDO-1 Inhibitor (LY3381916) as Monotherapy and in Combination With an Anti-PD-L1 Antibody (LY3300054) in Patients With Advanced Cancer IDO-1抑制剂 (LY3381916) 作为单一疗法并与Anti-PD-L1抗体 (LY3300054) 联合用于晚期癌症患者的I期研究 Kotecki, Nuria; Vuagnat, Perrine; O'Neil, Bert H.; Jalal, Shadia; Rottey, Sylvie; Prenen, Hans; Benhadji, Karim A.; Xia, Meng; Szpurka, Anna M.; Saha, Abhijoy; Wallin, Johan; Suriyapperuma, Subha; Galvao, Violeta R.; Geeganage, Sandaruwan; Doman, Thompson N.; Gandhi, Leena; Xu, Xiaojian; Bendell, Johanna 分享 收藏
A first-in-human phase I study of TAS0728, an oral covalent binding inhibitor of HER2, in patients with advanced solid tumors with HER2 or HER3 aberrations Piha-Paul, Sarina A.; Azaro, Analia; Arkenau, Hendrik Tobias; Oh, Do-Youn; Galsky, Matthew D.; Pal, Sumanta Kumar; Hamada, Kensuke; He, Yaohua; Yamamiya, Ikuo; Benhadji, Karim A.; Hollebecque, Antoine 分享 收藏
Trifluridine/tipiracil in patients with metastatic gastroesophageal junction cancer: a subgroup analysis from the phase 3 TAGS study Mansoor, Wasat; Arkenau, Hendrik-Tobias; Alsina, Maria; Shitara, Kohei; Thuss-Patience, Peter; Cuffe, Sinead; Dvorkin, Mikhail; Park, David; Ando, Takayuki; Van den Eynde, Marc; Beretta, Giordano D.; Zaniboni, Alberto; Doi, Toshihiko; Tabernero, Josep; Ilson, David H.; Makris, Lukas; Benhadji, Karim A.; Van Cutsem, Eric 分享 收藏
Safety and activity of the TGFβ receptor I kinase inhibitor galunisertib plus the anti-PD-L1 antibody durvalumab in metastatic pancreatic cancer Tgf β 受体I激酶抑制剂galunisertib和anti-PD-L1抗体durvalumab在转移性胰腺癌中的安全性和活性 Melisi, Davide; Oh, Do-Youn; Hollebecque, Antoine; Calvo, Emiliano; Varghese, Anna; Borazanci, Erkut; Macarulla, Teresa; Merz, Valeria; Zecchetto, Camilla; Zhao, Yumin; Gueorguieva, Ivelina; Man, Michael; Gandhi, Leena; Estrem, Shawn T.; Benhadji, Karim A.; Lanasa, Mark C.; Avsar, Emin; Guba, Susan C.; Garcia-Carbonero, Rocio 分享 收藏
A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors Azaro, Analia; Massard, Christophe; Tap, William D.; Cassier, Philippe A.; Merchan, Jaime; Italiano, Antoine; Anderson, Bailey; Yuen, Eunice; Yu, Danni; Oakley, Gerard, III; Benhadji, Karim A.; Pant, Shubham 分享 收藏
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