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Dominant-negative effects of Weaver syndrome-associated EZH2 variants Deevy, O.; Li, J.; Monger, C.; Matra, F.; Tuck, E.; Davies, M.; Badonyi, M.; Boyce, M.; Doyle, E.J.; Hokamp, K.; et al. 与Weaver综合征相关的EZH2变异的显性负效应。基因与发育. 2025. [Google Scholar] [CrossRef] Deevy, Orla; Li, Jingjing; Monger, Craig; Matra, Francesca; Tuck, Ellen; Davies, Molly; Badonyi, Mihaly; Boyce, Maeve; Doyle, Emma J.; Hokamp, Karsten; Nimmo, Darragh; Rodighiero, Simona; Zhang, Qi; Davidovich, Chen; Marsh, Joseph A.; Pasini, Diego; Conway, Eric; Bracken, Adrian P. 分享 收藏
A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells 非分裂细胞中向催化活性较低的Polycomb抑制复合体转变的保守开关 Mccole, Rachel; Nolan, James; Reck, David M.; Monger, Craig; Rustichelli, Samantha; Conway, Eric; Brien, Gerard L.; Wang, Cheng; Deevy, Orla; Neikes, Hannah K.; Bashore, Frances M.; Mooney, Aoibhinn; Flavin, Richard; Vandenberghe, Elisabeth; Flanigan, Sarena F.; Pasini, Diego; Davidovich, Chen; Vermeulen, Michiel; James, Lindsey I.; Healy, Evan; Bracken, Adrian P. 分享 收藏
Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes Cai, Wenjie; Liu, Xicheng; Barajas, Sergio; Xiao, Shiyu; Vemula, Sasidhar; Chen, Hongxia; Yang, Yuxia; Bochers, Christopher; Henley, Danielle; Liu, Sheng; Jia, Yuzhi; Hong, Michelle; Mays, Tiffany M.; Capitano, Maegan L.; Liu, Huiping; Ji, Peng; Gao, Zhonghua; Pasini, Diego; Wan, Jun; Yue, Feng; Platanias, Leonidas C.; Xi, Rongwen; Chen, Sisi; Liu, Yan 分享 收藏
WNT Oncogenic Transcription Requires MYC Suppression of Lysosomal Activity and EPCAM Stabilization in Gastric Tumors Mule, Patrizia; Fernandez-Perez, Daniel; Amato, Simona; Manganaro, Daria; Oldani, Paola; Brandini, Stefania; Diaferia, Giuseppe; Cuomo, Alessandro; Recordati, Camilla; Soriani, Chiara; Dondi, Ambra; Zanotti, Marika; Rustichelli, Samantha; Bisso, Andrea; Pece, Salvatore; Rodighiero, Simona; Natoli, Gioacchino; Amati, Bruno; Ferrari, Karin Johanna; Chiacchiera, Fulvio; Pasini, Diego 分享 收藏
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Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations 增加的基因组不稳定性和组织微环境的重塑是Arid1a突变致癌特性的基础 D'Ambrosio, Alessandro; Bressan, Davide; Ferracci, Elisa; Carbone, Francesco; Mule, Patrizia; Rossi, Federico; Barbieri, Caterina; Sorrenti, Elisa; Fiaccadori, Gaia; Detone, Thomas; Vezzoli, Elena; Bianchi, Salvatore; Sartori, Chiara; Corso, Simona; Fukuda, Akihisa; Bertalot, Giovanni; Falqui, Andrea; Barbareschi, Mattia; Romanel, Alessandro; Pasini, Diego; Chiacchiera, Fulvio 分享 收藏
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PCGF6 controls murine Tuft cell differentiation via H3K9me2 modification independently of Polycomb repression Del Vecchio, Annachiara; Mule, Patrizia; Fernandez-Perez, Daniel; Amato, Simona; Lattanzi, Georgia; Zanotti, Marika; Rustichelli, Samantha; Pivetti, Silvia; Oldani, Paola; Mariani, Andrea; Iommazzo, Fabiola; Koseki, Haruhiko; Facciotti, Federica; Tamburri, Simone; Ferrari, Karin J.; Pasini, Diego 分享 收藏
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1 Thomas, Jonathan F.; Valencia-Sanchez, Marco Igor; Tamburri, Simone; Gloor, Susan L.; Rustichelli, Samantha; Godinez-Lopez, Victoria; De Ioannes, Pablo; Lee, Rachel; Abini-Agbomson, Stephen; Gretarsson, Kristjan; Burg, Jonathan M.; Hickman, Allison R.; Sun, Lu; Gopinath, Saarang; Taylor, Hailey F.; Sun, Zu-Wen; Ezell, Ryan J.; Vaidya, Anup; Meiners, Matthew J.; Cheek, Marcus A.; Rice, William J.; Svetlov, Vladimir; Nudler, Evgeny; Lu, Chao; Keogh, Michael-Christopher; Pasini, Diego; Armache, Karim-Jean 分享 收藏
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PRC2.1-and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1 Glancy, Eleanor; Wang, Cheng; Tuck, Ellen; Healy, Evan; Amato, Simona; Neikes, Hannah K.; Mariani, Andrea; Mucha, Marlena; Vermeulen, Michiel; Pasini, Diego; Bracken, Adrian P. 分享 收藏
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NPAT expression is regulated by E2F and is essential for cell cycle progression Gao, G; Bracken, AP; Burkard, K; Pasini, D; Classon, M; Attwooll, C; Sagara, M; Imai, T; Helin, K; Zhao, JY 分享 收藏
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Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity Danovi, D; Meulmeester, E; Pasini, D; Migliorini, D; Capra, M; Frenk, R; de Graaf, P; Francoz, S; Gasparini, P; Gobbi, A; Helin, K; Pelicci, PG; Jochemsen, AG; Marine, JC 分享 收藏
Polycomb complex 2 is required for E-cadherin repression by the snail1 transcription factor Herranz, Nicolas; Pasini, Diego; Diaz, Victor M.; Franci, Clara; Gutierrez, Arantxa; Dave, Natalia; Escriva, Maria; Hernandez-Munoz, Inma; Di Croce, Luciano; Helin, Kristian; Garcia de Herreros, Antonio; Peiro, Sandra 分享 收藏
Amplification of Mdmx (or Mdm4) Directly Contributes to Tumor Formation by Inhibiting p53 Tumor Suppressor Activity (vol 24, pg 5835, 2004) Mdmx (或Mdm4) 的扩增通过抑制p53肿瘤抑制活性直接促进肿瘤形成 (vol 24，pg 5835，2004) Danovi, Davide; Meulmeester, Erik; Pasini, Diego; Migliorini, Domenico; Capra, Maria; Frenk, Ruth; de Graaf, Petra; Francoz, Sarah; Gasparini, Patrizia; Gobbi, Alberto; Helin, Kristian; Pelicci, Pier Giuseppe; Jochemsen, Aart G.; Marine, Jean-Christophe 分享 收藏
Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis Tanaskovic, Nina; Dalsass, Mattia; Filipuzzi, Marco; Ceccotti, Giorgia; Verrecchia, Alessandro; Nicoli, Paola; Doni, Mirko; Olivero, Daniela; Pasini, Diego; Koseki, Haruhiko; Sabo, Arianna; Bisso, Andrea; Amati, Bruno 分享 收藏
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