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M

Minal Barve

University of California System
H指数:33
被引数:6,991

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First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies

DT2216(一种选择性BCL-xL降解剂)的首次人体I期研究,用于治疗复发/难治性实体恶性肿瘤患者

2025-11-120
OAAI
Pirtobrutinib, a Highly Selective, Non-covalent (Reversible) BTKi in R/R Follicular Lymphoma: Phase 1/2 BRUIN Study

Pirtobrutinib,一种高选择性、非共价(可逆)BTKi在复发/难治性滤泡性淋巴瘤中的应用:BRUIN研究1/2期

2025-08-250
OAAI
Safety and Efficacy in Patients with Advanced Lymphomas from a Global Phase 1a/1b, First-in-Human Study of CS5001, a Novel Anti-ROR1 ADC

CS5001的安全性及有效性:一项全球性I期a/b、首次人体试验研究,该研究针对接受新型抗ROR1 ADC治疗的晚期淋巴瘤患者。

BLOOD
IF23.1
2024-11-050
PRE
Pirtobrutinib monotherapy in Bruton tyrosine kinase inhibitor-intolerant patients with B-cell malignancies: results of the phase I/II BRUIN trial
2024-10-032
OAAI
Safety, pharmacokinetics, pharmacodynamics, and antitumor activity of SAR439459, a TGFβ inhibitor, as monotherapy and in combination with cemiplimab in patients with advanced solid tumors: Findings from a phase 1/1b study

Tgf β 抑制剂SAR439459作为单药治疗和与cemiplimab联合治疗晚期实体瘤患者的安全性,药代动力学,药效学和抗肿瘤活性: 1/1b期研究的结果

2024-06-191
OA
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer

Adagrasib联合西妥昔单抗治疗KRASG12C-Mutated转移性结直肠癌的疗效和安全性

2024-04-0811
OAAI
First-in-human, dose escalation and expansion study of MT-6402, a novel engineered toxin body (ETB) targeting PD-L1, in patients with PD-L1 expressing relapsed/refractory advanced solid tumors: Interim data
2024-04-050
PRE
A Relative Bioavailability, Bioequivalence, and Food Effect Study of Niraparib Tablets in Patients with Advanced Solid Tumors

尼拉帕尼片在晚期实体瘤患者中的相对生物利用度,生物等效性和食物效应研究

2024-03-010
OAAI
Preliminary safety and pharmacokinetic profiles of RMC-6236, a first-in-class, RAS-selective, tri-complex RASMULTI(ON) inhibitor in patients with KRAS mutant solid tumors on the Phase 1 trial RMC-6236-001
2023-12-015
PRE
Open-label, phase II, multicenter study of lasofoxifene plus abemaciclib for treating women with metastatic ERD/HER2L breast cancer and an ESR1 mutation after disease progression on prior therapies: ELAINE 2

lasofoxifene联合abemaciclib治疗转移性ERD/HER2L乳腺癌和先前治疗疾病进展后ESR1突变的女性的开放标签,II期,多中心研究: ELAINE 2

2023-12-0114
OA
Pharmacokinetics and pharmacodynamics of IGM-8444, a first-in-class engineered pentameric DR5-targeting agonist IgM monoclonal antibody, in patients with R/R and newly diagnosed cancers
2023-12-010
PRE