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S

Sabine Merkelbach-Bruse

University of Cologne
H指数:55
被引数:9,625

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Rationale and Study Design of the GUIDANCE trial: A Multicenter Phase II Trial of Maintenance Durvalumab and Olaparib After Standard Fist Line Treatment (Carboplatin/Cisplatin, Etoposide, and Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC) (AIO-TRK-0124/ass)

GUIDANCE试验的原理与设计方案：一项多中心II期临床试验，旨在评估标准一线治疗（卡铂/顺铂、依托泊苷和度伐利尤单抗）后，对HRD阳性广泛期（ED）小细胞肺癌（SCLC）患者进行度伐利尤单抗和奥拉帕利维持治疗的疗效（AIO-TRK-0124/ass）

Clinical Lung Cancer
IF3.3
2026-09-010
PRE
Riedel, Richard; Verheyen, Malte; Michels, Sebastian; Ruge, Lea; Stilianakis, Sofia; Jakob, Carolin; Scharpenseel, Heather; Scheffler, Matthias; Nogova, Lucia; Schulmann, Karsten; Bozorgmehr, Farastuk; Grohe, Christian; Griesinger, Frank; Welter, Vanessa; Fassunke, Jana; Siemanowski-Hrach, Janna; Tolkach, Yuri; Siebolts, Udo; Merkelbach-Bruse, Sabine; Buettner, Reinhard; Wolf, Jurgen; John, Felix
Pitfalls in detecting MET exon 14 skipping variants by DNA- and RNA- based next generation sequencing technologies in a large real-world cohort and results of the first multinational EQA schemes

在大型真实世界队列中，通过基于DNA和RNA的下一代测序技术检测MET外显子14跳跃变异的陷阱及首个跨国EQA方案的初步结果

the journal of molecular diagnostics
IF0
2026-06-040
PRE
Carina Heydt; Michaela Angelika Ihle; Katharina Ilm; Jan Rehker; Peony Poon; Janna Siemanowski-Hrach; Roberto Pappesch; Svenja Wagener-Ryczek; Christoph Jonas; Jana Fassunke; Richard Riedel; Anne Maria Schultheis; Reinhard Buettner; Sabine Merkelbach-Bruse; Udo Siebolts
AI-powered spatial cell phenomics enhances risk stratification in non-small cell lung cancer

人工智能驱动的空间细胞表型学增强非小细胞肺癌的风险分层

Nature Communications
IF15.7
2025-11-030
OAAI
Simon Schallenberg; Gabriel Dernbach; Sharon Ruane; Philipp Jurmeister; Cornelius Böhm; Kai Standvoss; Sandip Ghosh; Marco Frentsch; Mihnea P. Dragomir; Philipp G. Keyl; Corinna Friedrich; Il-Kang Na; Sabine Merkelbach-Bruse; Alexander Quaas; Nikolaj Frost; Kyrill Boschung; Winfried Randerath; Georg Schlachtenberger; Matthias Heldwein; Ulrich Keilholz; Khosro Hekmat; Jens-Carsten Rückert; Reinhard Büttner; Angela Vasaturo; David Horst; Lukas Ruff; Maximilian Alber; Klaus-Robert Müller; Frederick Klauschen
CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma

CSF1R⁺髓系-单核细胞驱动侵袭性B细胞淋巴瘤中CAR-T细胞的耐药性

Cancer Cell
IF44.5
2025-06-120
OAAI
David Stahl; Philipp Gödel; Hyatt Balke-Want; Rahil Gholamipoorfard; Paul Segbers; Luis Tetenborg; Mirjam Koker; Janina Dörr; Lisa Gregor; Daniel Bachurski; France Rose; Adrian G. Simon; Zinaida Good; Josefine Jakob; Björn Häupl; Marieke Nill; Ruth Flümann; Tobias Riet; Dinah Lange; Stuart J. Blakemore; Herrad Baurmann; Conrad-Amadeus Voltin; Nicole Potter; Lilli Schlözer; Max Freihammer; Svenja Wagener-Ryczek; Andra-Iza Iuga; Jan-Michel Heger; Hanna Ludwig; Julia K. Schleifenbaum; Jessica Propp; Paul J. Bröckelmann; Ron D. Jachimowicz; Gero Knittel; Sven Borchmann; Sabine Merkelbach-Bruse; Christian Pallasch; Martin Peifer; Jan Rybniker; Alexander Quaas; Mark Nitz; Johannes Brägelmann; Werner Müller; Thorsten Persigehl; Katarzyna Bozek; Sebastian J. Theobald; Reinhard Büttner; Thomas Oellerich; Michael Hallek; Sebastian Kobold; Markus Chmielewski; Hans Christian Reinhardt; Crystal Mackall; Nima Abedpour; Peter Borchmann; Roland T. Ullrich
Assessment of p53 in Endometrial Carcinoma Biopsy and Corresponding Hysterectomy Cases in a Real-World Setting: Which Cases Need Molecular Work-Up?

评估真实世界背景下子宫内膜癌活检及对应子宫切除术病例中p53的情况：哪些病例需要进行分子检测？

CANCERS
IF4.4
2025-04-290
OA
Eich, Marie-Lisa; Siemanowsk-Hrach, Janna; Drebber, Uta; Friedrichs, Nicolaus; Mallmann, Peter; Domroese, Christian; Ratiu, Dominik; Merkelbach-Bruse, Sabine; Buettner, Reinhard; Quaas, Alexander; Schoemig-Markiefka, Birgid
Indirect comparison of capmatinib treatment from GEOMETRY mono-1 trial to SOC in German patients with locally advanced or metastatic NSCLC harboring METex14 skipping mutations [Eur J Cancer 207 (2024) 114158]
EUROPEAN JOURNAL OF CANCER
IF7.1
2024-12-010
OAAI
Kron, Anna; Scheffler, Matthias; Wiesweg, Marcel; Hummel, Horst-Dieter; Kulhavy, Jonas; Gatteloehner, Stefan; Kollmeier, Jens; Schubart, Christoph; Gross, Thorben; Demes, Melanie-Christin; Keymel, Stefanie; Joosten, Maria; Merkelbach-Bruse, Sabine; Woelwer, Christina Bianca; Tufman, Amanda; Kauffmann-Guerrero, Diego; Oeser, Katharina; Zehaczek, Melanie; Jeratsch, Ulli; Wolf, Juergen
Indirect comparison of capmatinib treatment from GEOMETRY mono-1 trial to SOC in German patients with locally advanced or metastatic NSCLC harboring METex14 skipping mutations
EUROPEAN JOURNAL OF CANCER
IF7.1
2024-08-012
OAAI
Kron, Anna; Scheffler, Matthias; Wiesweg, Marcel; Hummel, Horst-Dieter; Kulhavy, Jonas; Gatteloehner, Stefan; Kollmeier, Jens; Schubart, Christoph; Gross, Thorben; Demes, Melanie-Christin; Keymel, Stefanie; Joosten, Maria; Merkelbach-Bruse, Sabine; Woelwer, Christina Bianca; Tufman, Amanda; Kauffmann-Guerrero, Diego; Oeser, Katharina; Zehaczek, Melanie; Jeratsch, Ulli; Wolf, Juergen
AI-driven, mIF-based cell-omics reveals spatially resolved cell signature for outcome prediction in NSCLC patients
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Schallenberg, Simon; Dernbach, Gabriel; Ruane, Sharon; Bohm, Cornelius; Ruff, Lukas; Standvoss, Kai; Ghosh, Sandip; Frentsch, Marco; Dragomir, Mihnea; Fritz, Rebecca; Koch, Ines; Friedrich, Corinna; Na, Il-Kang; Merkelbach-Bruse, Sabine; Quaas, Alexander; Frost, Nikolaj; Boschung, Kyrill; Randerath, Winfried; Schlachtenberger, Georg; Heldwein, Matthias; Keilholz, Ulrich; Hekmat, Khosro; Ruckert, Jens; Buttner, Reinhard; Vasaturo, Angela; Horst, David; Alber, Maximilian; Klauschen, Frederick
TTF-1 status in early-stage lung adenocarcinoma is an independent predictor of relapse and survival superior to tumor grading
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Schallenberg, Simon; Dernbach, Gabriel; Dragomir, Mihnea; Schlachtenberger, Georg; Boschung, Kyrill; Friedrich, Corinna; Standvoss, Kai; Ruff, Lukas; Anders, Philipp; Grohe, Christian; Randerath, Winfried; Merkelbach-Bruse, Sabine; Quaas, Alexander; Heldwein, Matthias; Keilholz, Ulrich; Hekmat, Khosro; Ruckert, Jens; Buttner, Reinhard; Horst, David; Klauschen, Frederick; Frost, Nikolaj
Overall survival and central nervous system activity of crizotinib in ROS1-rearranged lung cancerdfinal results of the EUCROSS trial
ESMO OPEN
IF8.3
2024-02-011
OAAI
Michels, S.; Massuti, B.; Vasyliv, I.; Stratmann, J.; Frank, J.; Adams, A.; Felip, E.; Grohe, C.; Rodriguez-Abreu, D.; Bischoff, H.; Costa, E. Carcereny i; Pereira, E.; Corral, J.; Fassunke, J.; Fischer, R. N.; Insa, A.; Koleczko, S.; Nogova, L.; Reck, M.; Reutter, T.; Riedel, R.; Schau, D.; Schefler, M.; Weisthoff, M.; Provencio, M.; Merkelbach-Bruse, S.; Hellmich, M.; Sebastian, M.; Buettner, R.; Roseli, R.; Persigehl, T.; Wolf, J.
TTF-1 status in early-stage lung adenocarcinoma is an independent predictor of relapse and survival superior to tumor grading
EUROPEAN JOURNAL OF CANCER
IF7.1
2024-01-012
OA
Schallenberg, Simon; Dernbach, Gabriel; Dragomir, Mihnea P.; Schlachtenberger, Georg; Boschung, Kyrill; Friedrich, Corinna; Standvoss, Kai; Ruff, Lukas; Anders, Philipp; Grohe, Christian; Randerath, Winfried; Merkelbach-Bruse, Sabine; Quaas, Alexander; Heldwein, Matthias; Keilholz, Ulrich; Hekmat, Jens Khosro; Rueckert, Carsten; Buettner, Reinhard; Horst, David; Klauschen, Frederick; Frost, Nikolaj
Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2023-11-013
OAAI
Malchers, Florian; Nogova, Lucia; van Attekum, Martijn H. A.; Maas, Lukas; Braegelmann, Johannes; Bartenhagen, Christoph; Girard, Luc; Bosco, Graziella; Dahmen, Ilona; Michels, Sebastian; Weeden, Clare E.; Scheel, Andreas H.; Meder, Lydia; Golfmann, Kristina; Schuldt, Philipp; Siemanowski, Janna; Rehker, Jan; Merkelbach-Bruse, Sabine; Menon, Roopika; Gautschi, Oliver; Heuckmann, Johannes M.; Brambilla, Elisabeth; Asselin-Labat, Marie-Liesse; Persigehl, Thorsten; Minna, John D.; Walczak, Henning; Ullrich, Roland T.; Fischer, Matthias; Reinhardt, Hans Christian; Wolf, Juergen; Buettner, Reinhard; Peifer, Martin; George, Julie; Thomas, Roman K.

研究方向

暂未获取到该数据
R
Reinhard Büttner
H 指数:87论文数:1,013被引数:2.9万
C
Carina Heydt
H 指数:26论文数:108被引数:2,653
J
Jana Fassunke
H 指数:28论文数:116被引数:3,422
E
Eva Wardelmann
H 指数:70论文数:689被引数:2.2万
H
Hans‐Ulrich Schildhaus
H 指数:47论文数:346被引数:9,365
S
Sebastian Michels
H 指数:26论文数:173被引数:5,435
R
Reinhard Buettner
H 指数:77论文数:707被引数:2.4万
M
Matthias Scheffler
H 指数:46论文数:440被引数:7,749
M
Michaela A. Ihle
H 指数:24论文数:88被引数:2,583
A
Anne M. Schultheis
H 指数:38论文数:179被引数:5,516