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T

Tamsin R.M. Lannagan

cruk scotland institute
H指数:19
被引数:1,986

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Correction: JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal‑rich

纠正：JAK/STAT3是富基质结直肠癌患者的治疗靶点

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2026-08-150
OAAI
Kathryn A. F. Pennel; Phimmada Hatthakarnkul; Colin S. Wood; Guang‑Yu Lian; Sara S. F. Al‑Badran; Jean A. Quinn; Assya Legrini; Jitwadee Inthagard; Peter G. Alexander; Hester van Wyk; Ahmad Kurniawan; Umar Hashmi; Michael A. Gillespie; Megan Mills; Aula Ammar; Jennifer Hay; Ditte Andersen; Colin Nixon; Selma Rebus; David K. Chang; Caroline Kelly; Andrea Harkin; Janet Graham; David Church; Ian Tomlinson; Mark Saunders; Tim Iveson; Tamsin R. M. Lannagan; Rene Jackstadt; Noori Maka; Paul G. Horgan; Campbell S. D. Roxburgh; Owen J. Sansom; Donald C. McMillan; Colin W. Steele; Nigel B. Jamieson; James H. Park; Antonia K. Roseweir; Joanne Edwards
Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state

病毒模拟将免疫抑制性结直肠癌景观重定向为促炎性和CMS1样再生状态

Communications Biology
IF5.1
2026-05-260
OAAI
Shania M. Corry; Svetlana Sakhnevych; Noha Ehssan Mohamed; Sudhir B. Malla; Ryan Byrne; Andrew Young; Raheleh Amirkhah; Courtney Bull; Andrea Lees; Keara Redmond; Tamsin R. M. Lannagan; Rachel A. Ridgway; Fiona R. Taggart; Natalie C. Fisher; Tim Maughan; Mark Lawler; Andrew D. Campbell; Simon J. Leedham; Aideen E. Ryan; Daniel B. Longley; Donna M. Small; Owen J. Sansom; Philip D. Dunne
MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance

MAPK驱动的上皮细胞可塑性驱动结直肠癌治疗抵抗

Nature
IF48.5
2025-11-240
PRE
Mark White; Megan L. Mills; Laura M. Millett; Kathryn Gilroy; Yourae Hong; Lucas B. Zeiger; Rosalin J. Simpson; Shania M. Corry; Amelia Ligeza; Tamsin R. M. Lannagan; Susanti Susanti; Rachel A. Ridgway; Ayse S. Yazgili; Lucile Grzesiak; Raheleh Amirkhah; Catriona A. Ford; Nikola Vlahov; Hannah Tovell; Leah Officer-Jones; Catherine Ficken; Rachel Pennie; Arafath K. Najumudeen; Alexander Raven; Nadia Nasreddin; Ekansh Chauhan; Andrew S. Papanastasiou; Colin Nixon; Vivienne Morrison; Rene Jackstadt; Janet S. Graham; Crispin J. Miller; Sarah J. Ross; Simon T. Barry; Valeria Pavet; Richard H. Wilson; John Le Quesne; Philip D. Dunne; Sabine Tejpar; Simon Leedham; Andrew D. Campbell; Owen J. Sansom
Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
CANCER DISCOVERY
IF33.3
2024-08-120
OAAI
Loi, Patrick; Schade, Amy E.; Rodriguez, Carrie L.; Krishnan, Anjana; Perurena, Naiara; Nguyen, Van T. M.; Xu, Yilin; Watanabe, Marina; Davis, Rachel A.; Gardner, Alycia; Pilla, Natalie F.; Mattioli, Kaia; Popow, Olesja; Gunduz, Nuray; Lannagan, Tamsin R. M.; Fitzgerald, Samantha; Sicinska, Ewa T.; Lin, Jia-Ren; Tan, William; Brais, Lauren K.; Haigis, Kevin M.; Giannakis, Marios; Ng, Kimmie; Santagata, Sandro; Helin, Kristian; Sansom, Owen J.; Cichowski, Karen
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024)
NATURE GENETICS
IF31.8
2024-06-031
OAAI
Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
Single cell RNA sequencing of human and murine cancers demonstrates metastases-specific neutrophil phenotypes driven by the IL-1β/CXCR2 signaling axis - Disruption of this pathway abrogates neutrophil immunosuppressive effects and reduces tumor burden
CANCER RESEARCH
IF16.6
2024-03-220
PRE
McLaren, Alistair S.; Fetit, Rana; White, Mark; Mills, Megan L.; Lannagan, Tamsin; Falconer, John; Cortes-Lavaud, Xabier; Gilroy, Kathryn; Ridgway, Rachel; Nixon, Colin; Naiker, Varushka; Njunge, Renee; Clarke, Cassie J.; Whyte, Declan; Kirschner, Kristina; Jackstadt, Rene; Norman, Jim C.; Carlin, Leo M.; Campbell, Andrew D.; Sansom, Owen J.; Steele, Colin W.
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2024-03-018
OAAI
Pennel, Kathryn A. F.; Hatthakarnkul, Phimmada; Wood, Colin S.; Lian, Guang-Yu; Al-Badran, Sara S. F.; Quinn, Jean A.; Legrini, Assya; Inthagard, Jitwadee; Alexander, Peter G.; van Wyk, Hester; Kurniawan, Ahmad; Hashmi, Umar; Gillespie, Michael A.; Mills, Megan; Ammar, Aula; Hay, Jennifer; Andersen, Ditte; Nixon, Colin; Rebus, Selma; Chang, David K.; Kelly, Caroline; Harkin, Andrea; Graham, Janet; Church, David; Tomlinson, Ian; Saunders, Mark; Iveson, Tim; Lannagan, Tamsin R. M.; Jackstadt, Rene; Maka, Noori; Horgan, Paul G.; Roxburgh, Campbell S. D.; Sansom, Owen J.; McMillan, Donald C.; Steele, Colin W.; Jamieson, Nigel B.; Park, James H.; Roseweir, Antonia K.; Edwards, Joanne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer
NATURE GENETICS
IF31.8
2024-02-1310
OAAI
Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia
NATURE COMMUNICATIONS
IF15.7
2024-01-2022
OAAI
Gurbatri, Candice R.; Radford, Georgette A.; Vrbanac, Laura; Im, Jongwon; Thomas, Elaine M.; Coker, Courtney; Taylor, Samuel R.; Jang, Younguk; Sivan, Ayelet; Rhee, Kyu; Saleh, Anas A.; Chien, Tiffany; Zandkarimi, Fereshteh; Lia, Ioana; Lannagan, Tamsin R. M.; Wang, Tongtong; Wright, Josephine A.; Kobayashi, Hiroki; Ng, Jia Q.; Lawrence, Matt; Sammour, Tarik; Thomas, Michelle; Lewis, Mark; Papanicolas, Lito; Perry, Joanne; Fitzsimmons, Tracy; Kaazan, Patricia; Lim, Amanda; Stavropoulos, Alexandra M.; Gouskos, Dion A.; Marker, Julie; Ostroff, Cheri; Rogers, Geraint; Arpaia, Nicholas; Worthley, Daniel L.; Woods, Susan L.; Danino, Tal
Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis
NATURE COMMUNICATIONS
IF15.7
2023-10-313
OAAI
Ng, Jia Q.; Jafarov, Toghrul H.; Little, Christopher B.; Wang, Tongtong; Ali, Abdullah M.; Ma, Yan; Radford, Georgette A.; Vrbanac, Laura; Ichinose, Mari; Whittle, Samuel; Hunter, David J.; Lannagan, Tamsin R. M.; Suzuki, Nobumi; Goyne, Jarrad M.; Kobayashi, Hiroki; Wang, Timothy C.; Haynes, David R.; Menicanin, Danijela; Gronthos, Stan; Worthley, Daniel L.; Woods, Susan L.; Mukherjee, Siddhartha
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target

代谢谱分析将结直肠癌分层并揭示腺苷同型半胱氨酸酶作为治疗靶标

NATURE METABOLISM
IF20.8
2023-08-1413
OAAI
Voorde, Johan Vande; Steven, Rory T.; Najumudeen, Arafath K.; Ford, Catriona A.; Dexter, Alex; Gonzalez-Fernandez, Ariadna; Nikula, Chelsea J.; Xiang, Yuchen; Ford, Lauren; Stavrakaki, Stefania Maneta; Gilroy, Kathryn; Zeiger, Lucas B.; Pennel, Kathryn; Hatthakarnkul, Phimmada; Elia, Efstathios A.; Nasif, Ammar; Murta, Teresa; Manoli, Eftychios; Mason, Sam; Gillespie, Michael; Lannagan, Tamsin R. M.; Vlahov, Nikola; Ridgway, Rachel A.; Nixon, Colin; Raven, Alexander; Mills, Megan; Athineos, Dimitris; Kanellos, Georgios; Nourse, Craig; Gay, David M.; Hughes, Mark; Burton, Amy; Yan, Bin; Sellers, Katherine; Wu, Vincen; De Ridder, Kobe; Shokry, Engy; Uribe, Alejandro Huerta; Clark, William; Clark, Graeme; Kirschner, Kristina; Thienpont, Bernard; Li, Vivian S. W.; Maddocks, Oliver D. K.; Barry, Simon T.; Goodwin, Richard J. A.; Kinross, James; Edwards, Joanne; Yuneva, Mariia O.; Sumpton, David; Takats, Zoltan; Campbell, Andrew D.; Bunch, Josephine; Sansom, Owen J.
MmCMS: mouse models' consensus molecular subtypes of colorectal cancer
BRITISH JOURNAL OF CANCER
IF6.8
2023-01-3010
OA
Amirkhah, Raheleh; Gilroy, Kathryn; Malla, Sudhir B. B.; Lannagan, Tamsin R. M.; Byrne, Ryan M. M.; Fisher, Natalie C. C.; Corry, Shania M. M.; Mohamed, Noha-Ehssan; Naderi-Meshkin, Hojjat; Mills, Megan L. L.; Campbell, Andrew D. D.; Ridgway, Rachel A. A.; Ahmaderaghi, Baharak; Murray, Richard; Llergo, Antoni Berenguer; Sanz-Pamplona, Rebeca; Villanueva, Alberto; Batlle, Eduard; Salazar, Ramon; Lawler, Mark; Sansom, Owen J. J.; Dunne, Philip D. D.
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia (vol 29, pg 1213, 2022)
CELL STEM CELL
IF20.4
2022-11-010
OA
Vazquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Eggington, Holly R.; Schenck, Ryan O.; Wouters, Valerie M.; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R. M.; Flanagan, Dustin J.; Najumudeen, Arafath K.; Omwenga, Sulochana; McCorry, Amy M. B.; Easton, Alistair; Koelzer, Viktor H.; East, James E.; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D.; Loughrey, Maurice B.; Dunne, Philip D.; Tsantoulis, Petros; Huels, David J.; Tejpar, Sabine; Sansom, Owen J.; Leedham, Simon J.
Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging

Traject3d允许通过实时成像在3D培养物中无标记鉴定不同的共现表型

NATURE COMMUNICATIONS
IF15.7
2022-09-0913
OAAI
Freckmann, Eva C.; Sandilands, Emma; Cumming, Erin; Neilson, Matthew; Roman-Fernandez, Alvaro; Nikolatou, Konstantina; Nacke, Marisa; Lannagan, Tamsin R. M.; Hedley, Ann; Strachan, David; Salji, Mark; Morton, Jennifer P.; McGarry, Lynn; Leung, Hing Y.; Sansom, Owen J.; Miller, Crispin J.; Bryant, David M.
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia

结肠直肠肿瘤中动态和适应性的癌症干细胞群混合

CELL STEM CELL
IF20.4
2022-08-0146
OAAI
Vasquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Eggington, Holly R.; Schenck, Ryan O.; Wouters, Valerie M.; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R. M.; Flanagan, Dustin J.; Najumudeen, Arafath K.; Omwenga, Sulochana; McCorry, Amy M. B.; Easton, Alistair; Koelzer, Viktor H.; East, James E.; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D.; Loughrey, Maurice B.; Dunne, Philip D.; Tsantoulis, Petros; Huels, David J.; Tejpar, Sabine; Sansom, Owen J.; Leedham, Simon J.

研究方向

暂未获取到该数据
O
Owen J. Sansom
H 指数:113论文数:1,190被引数:5.1万
A
Andrew D. Campbell
H 指数:39论文数:325被引数:6,404
S
Susan L. Woods
H 指数:29论文数:149被引数:5,088
T
Tongtong Wang
H 指数:31论文数:177被引数:4,363
S
Simon J. Leedham
H 指数:45论文数:396被引数:7,002
J
Jia Q. Ng
H 指数:18论文数:41被引数:2,203
K
Kathryn Gilroy
H 指数:19论文数:264被引数:2,263
L
Laura Vrbanac
H 指数:10论文数:48被引数:1,013
H
Hiroki Kobayashi
H 指数:20论文数:97被引数:2,462
R
René Jackstadt
H 指数:29论文数:166被引数:4,594