Andrew D. Campbell - Publications, H-index & Citations

Andrew D. Campbell

Cancer Research UK Scotland Institute

39H指数

325论文数

6.3K被引数

收录论文 70

发表时间

The cartography of KRAS inhibitor resistance in colorectal cancer KRAS抑制剂在结直肠癌中的耐药性图谱

Cancer Cell

IF44.5

2026-06-11

PREAI

Mark White; Andrew D. Campbell; Owen J. Sansom

Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state 病毒模拟将免疫抑制性结直肠癌景观重定向为促炎性和CMS1样再生状态

Communications Biology

IF5.1

2026-05-26

OAAI

Shania M. Corry; Svetlana Sakhnevych; Noha Ehssan Mohamed; Sudhir B. Malla; Ryan Byrne; Andrew Young; Raheleh Amirkhah; Courtney Bull; Andrea Lees; Keara Redmond; Tamsin R. M. Lannagan; Rachel A. Ridgway; Fiona R. Taggart; Natalie C. Fisher; Tim Maughan; Mark Lawler; Andrew D. Campbell; Simon J. Leedham; Aideen E. Ryan; Daniel B. Longley; Donna M. Small; Owen J. Sansom; Philip D. Dunne

SOX2 confers tumour permissiveness in a specific skin progenitor population SOX2赋予特定皮肤祖细胞群体以肿瘤易感性

Nature Communications

IF15.7

2026-01-08

OAAI

Patricia P. Centeno; Christopher Chester; Georgios Kanellos; Catriona A. Ford; Patrizia Cammareri; Gareth J. Inman; Thomas Jamieson; Rachel A. Ridgway; Richard Marais; Andrew D. Campbell; Owen J. Sansom

Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation 核磷蛋白支持WNT驱动的过度增殖和肿瘤启动

Nature Genetics

IF29

2025-12-18

OAAI

Georgios Kanellos; Chiara Giacomelli; Alexander Raven; Nikola Vlahov; Hu Jin; Pauline Herviou; Sudhir B. Malla; Nadia Nasreddin; Patricia P. Centeno; Constantinos Alexandrou; Kathryn Gilroy; Rachel L. Baird; Kathryn Pennel; June Munro; Joseph A. Waldron; Holly Hall; Leah Officer-Jones; Sheila Bryson; Douglas Strathdee; Sergio Lilla; Sara Zanivan; Vivienne Morrison; Colin Nixon; Rachel A. Ridgway; Crispin Miller; John R. P. Knight; Andrew D. Campbell; Philip D. Dunne; John Le Quesne; Joanne Edwards; Peter J. Park; Martin Bushell; Owen J. Sansom

MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance MAPK驱动的上皮细胞可塑性驱动结直肠癌治疗抵抗

Nature

IF48.5

2025-11-24

PREAI

Mark White; Megan L. Mills; Laura M. Millett; Kathryn Gilroy; Yourae Hong; Lucas B. Zeiger; Rosalin J. Simpson; Shania M. Corry; Amelia Ligeza; Tamsin R. M. Lannagan; Susanti Susanti; Rachel A. Ridgway; Ayse S. Yazgili; Lucile Grzesiak; Raheleh Amirkhah; Catriona A. Ford; Nikola Vlahov; Hannah Tovell; Leah Officer-Jones; Catherine Ficken; Rachel Pennie; Arafath K. Najumudeen; Alexander Raven; Nadia Nasreddin; Ekansh Chauhan; Andrew S. Papanastasiou; Colin Nixon; Vivienne Morrison; Rene Jackstadt; Janet S. Graham; Crispin J. Miller; Sarah J. Ross; Simon T. Barry; Valeria Pavet; Richard H. Wilson; John Le Quesne; Philip D. Dunne; Sabine Tejpar; Simon Leedham; Andrew D. Campbell; Owen J. Sansom

Use of metabolic imaging to monitor heterogeneity of tumour response following therapeutic mTORC1/2 pathway inhibition 使用代谢成像监测治疗性mTORC1/2通路抑制后肿瘤反应的异质性

DISEASE MODELS & MECHANISMS

IF3.3

2025-02-28

OAAI

Ling, Stephanie; Dexter, Alex; Race, Alan M.; Sharma, Shreya; Hamm, Gregory; Polanska, Urszula M.; Marshall, John F.; Takats, Zoltan; Brindle, Kevin; Yuneva, Mariia O.; Poulogiannis, George; Campbell, Andrew D.; Sansom, Owen J.; Goodwin, Richard J. A.; Bunch, Josephine; Barry, Simon T.

Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ

NATURE CELL BIOLOGY

IF19.1

2024-11-13

OAAI

Kiourtis, Christos; Terradas-Terradas, Maria; Gee, Lucy M.; May, Stephanie; Georgakopoulou, Anastasia; Collins, Amy L.; O'Sullivan, Eoin D.; Baird, David P.; Hassan, Mohsin; Shaw, Robin; Tan, Ee Hong; Mueller, Miryam; Engelmann, Cornelius; Andreola, Fausto; Hsieh, Ya-Ching; Reed, Lee H.; Borthwick, Lee A.; Nixon, Colin; Clark, William; Hanson, Peter S.; Sumpton, David; Mackay, Gillian; Suzuki, Toshiyasu; Najumudeen, Arafath K.; Inman, Gareth J.; Campbell, Andrew; Barry, Simon T.; Quaglia, Alberto; Morris, Christopher M.; Lebeau, Fiona E. N.; Sansom, Owen J.; Kirschner, Kristina; Jalan, Rajiv; Oakley, Fiona; Bird, Thomas G.

First Multikilogram Synthesis of the Next-Generation Oral Selective ERα Degrader Camizestrant

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2024-06-07

PREAI

Tatton, Matthew R.; Currie, Gordon S.; Adams, Bradley; Aurell, Carl-Johan; Broberg, Karl; Campbell, Andrew D.; Dai, Kuangchu; Malmgren, Marcus; Ikin, Andrew; Janbon, Sophie L. M.; Sims, Martin; Hemming-Taylor, Joanna; Winterbottom, Victoria

Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024)

NATURE GENETICS

IF31.8

2024-06-03

OAAI

Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.

Single cell RNA sequencing of human and murine cancers demonstrates metastases-specific neutrophil phenotypes driven by the IL-1β/CXCR2 signaling axis - Disruption of this pathway abrogates neutrophil immunosuppressive effects and reduces tumor burden

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

McLaren, Alistair S.; Fetit, Rana; White, Mark; Mills, Megan L.; Lannagan, Tamsin; Falconer, John; Cortes-Lavaud, Xabier; Gilroy, Kathryn; Ridgway, Rachel; Nixon, Colin; Naiker, Varushka; Njunge, Renee; Clarke, Cassie J.; Whyte, Declan; Kirschner, Kristina; Jackstadt, Rene; Norman, Jim C.; Carlin, Leo M.; Campbell, Andrew D.; Sansom, Owen J.; Steele, Colin W.

Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer

NATURE GENETICS

IF31.8

2024-02-13

OAAI

Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.

KRAS allelic imbalance drives tumour initiation yet suppresses metastasis in colorectal cancer in vivo

NATURE COMMUNICATIONS

IF15.7

2024-01-02

OAAI

Najumudeen, Arafath K.; Fey, Sigrid K.; Millett, Laura M.; Ford, Catriona A.; Gilroy, Kathryn; Gunduz, Nuray; Ridgway, Rachel A.; Anderson, Eve; Strathdee, Douglas; Clark, William; Nixon, Colin; Morton, Jennifer P.; Campbell, Andrew D.; Sansom, Owen J.

Pre-clinical modelling and treatment of BRAF mutated colorectal cancer

ANNALS OF ONCOLOGY

IF65.4

2023-10-01

PREAI

White, M.; Lannagan, T.; McGarry, L.; Carlin, L.; Mills, M.; Yazgili, A. S.; Ridgway, R.; Jackstadt, R.; Campbell, A. D.; Wilson, R. H.; Sansom, O. J.

Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression

NATURE COMMUNICATIONS

IF15.7

2023-08-25

OAAI

Bailey, Peter; Ridgway, Rachel A.; Cammareri, Patrizia; Treanor-Taylor, Mairi; Bailey, Ulla-Maja; Schoenherr, Christina; Bone, Max; Schreyer, Daniel; Purdie, Karin; Thomson, Jason; Rickaby, William; Jackstadt, Rene; Campbell, Andrew D.; Dimonitsas, Emmanouil; Stratigos, Alexander J.; Arron, Sarah T.; Wang, Jun; Blyth, Karen; Proby, Charlotte M.; Harwood, Catherine A.; Sansom, Owen J.; Leigh, Irene M.; Inman, Gareth J.

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target 代谢谱分析将结直肠癌分层并揭示腺苷同型半胱氨酸酶作为治疗靶标

NATURE METABOLISM

IF20.8

2023-08-14

OAAI

Voorde, Johan Vande; Steven, Rory T.; Najumudeen, Arafath K.; Ford, Catriona A.; Dexter, Alex; Gonzalez-Fernandez, Ariadna; Nikula, Chelsea J.; Xiang, Yuchen; Ford, Lauren; Stavrakaki, Stefania Maneta; Gilroy, Kathryn; Zeiger, Lucas B.; Pennel, Kathryn; Hatthakarnkul, Phimmada; Elia, Efstathios A.; Nasif, Ammar; Murta, Teresa; Manoli, Eftychios; Mason, Sam; Gillespie, Michael; Lannagan, Tamsin R. M.; Vlahov, Nikola; Ridgway, Rachel A.; Nixon, Colin; Raven, Alexander; Mills, Megan; Athineos, Dimitris; Kanellos, Georgios; Nourse, Craig; Gay, David M.; Hughes, Mark; Burton, Amy; Yan, Bin; Sellers, Katherine; Wu, Vincen; De Ridder, Kobe; Shokry, Engy; Uribe, Alejandro Huerta; Clark, William; Clark, Graeme; Kirschner, Kristina; Thienpont, Bernard; Li, Vivian S. W.; Maddocks, Oliver D. K.; Barry, Simon T.; Goodwin, Richard J. A.; Kinross, James; Edwards, Joanne; Yuneva, Mariia O.; Sumpton, David; Takats, Zoltan; Campbell, Andrew D.; Bunch, Josephine; Sansom, Owen J.

KRAS allelic imbalance drives an epithelial MAPK-dependent tumor initiation program that is inefficient in provoking metastasis in colorectal cancer in vivo

MOLECULAR CANCER RESEARCH

IF4.7

2023-05-01

PREAI

Najumudeen, Arafath K.; Fey, Sigrid K.; Campbell, Andrew D.; Sansom, Owen J.

Therapeutic targeting of tumour myeloid cells 肿瘤髓系细胞的靶向治疗

NATURE REVIEWS CANCER

IF66.8

2023-02-06

PREAI

Barry, Simon T.; Gabrilovich, Dmitry I.; Sansom, Owen J.; Campbell, Andrew D.; Morton, Jennifer P.

MmCMS: mouse models' consensus molecular subtypes of colorectal cancer

BRITISH JOURNAL OF CANCER

IF6.8

2023-01-30

OAAI

Amirkhah, Raheleh; Gilroy, Kathryn; Malla, Sudhir B. B.; Lannagan, Tamsin R. M.; Byrne, Ryan M. M.; Fisher, Natalie C. C.; Corry, Shania M. M.; Mohamed, Noha-Ehssan; Naderi-Meshkin, Hojjat; Mills, Megan L. L.; Campbell, Andrew D. D.; Ridgway, Rachel A. A.; Ahmaderaghi, Baharak; Murray, Richard; Llergo, Antoni Berenguer; Sanz-Pamplona, Rebeca; Villanueva, Alberto; Batlle, Eduard; Salazar, Ramon; Lawler, Mark; Sansom, Owen J. J.; Dunne, Philip D. D.

RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells RAC1B功能对于乳腺癌干细胞的维持和乳腺肿瘤细胞的化学抗性至关重要

ONCOGENE

IF7.3

2023-01-05

OAAI

Chen, Fuhui; Gurler, Sevim B.; Novo, David; Selli, Cigdem; Alferez, Denis G.; Eroglu, Secil; Pavlou, Kyriaki; Zhang, Jingwei; Sims, Andrew H.; Humphreys, Neil E.; Adamson, Antony; Campbell, Andrew; Sansom, Owen J.; Tournier, Cathy; Clarke, Robert B.; Brennan, Keith; Streuli, Charles H.; Ucar, Ahmet

Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features 上皮tgf β 参与生长因子信号传导以避免细胞凋亡并以侵袭性特征驱动肠道肿瘤发生

NATURE COMMUNICATIONS

IF15.7

2022-12-07

OAAI

Flanagan, Dustin J.; Amirkhah, Raheleh; Vincent, David F.; Gunduz, Nuray; Gentaz, Pauline; Cammareri, Patrizia; McCooey, Aoife J.; McCorry, Amy M. B.; Fisher, Natalie C.; Davis, Hayley L.; Ridgway, Rachel A.; Lohuis, Jeroen; Leach, Joshua D. G.; Jackstadt, Rene; Gilroy, Kathryn; Mariella, Elisa; Nixon, Colin; Clark, William; Hedley, Ann; Markert, Elke K.; Strathdee, Douglas; Bartholin, Laurent; Redmond, Keara L.; Kerr, Emma M.; Longley, Daniel B.; Ginty, Fiona; Cho, Sanghee; Coleman, Helen G.; Loughrey, Maurice B.; Bardelli, Alberto; Maughan, Timothy S.; Campbell, Andrew D.; Lawler, Mark; Leedham, Simon J.; Barry, Simon T.; Inman, Gareth J.; van Rheenen, Jacco; Dunne, Philip D.; Sansom, Owen J.

研究方向