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L

Leo M. Carlin

cancer research uk beatson institute
H指数:33
被引数:5,842

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Multiscale in vivo imaging of tumor evolution using a germline conditional triple-reporter mouse

利用种系条件三报告小鼠对肿瘤演化的多尺度活体成像

Nature Biotechnology
IF41.7
2026-07-150
OAAI
Ximena L. Raffo-Iraolagoitia; Abdullah Alyamani; Stephanie May; David Stevenson; Agata Mackintosh; Lynn McGarry; Jayanthi Anand; Dmitry Soloviev; Gavin Brown; Colin Nixon; Chrysa Kapeni; Maike De La Roche; Karen Blyth; Thomas Graham Bird; Douglas Strathdee; Scott K. Lyons; Gilbert Fruhwirth; Leo M. Carlin; David Y. Lewis
Vγ1 γδ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model

Vγ1 γδ T细胞在自发性肺癌小鼠模型中引导气道巨噬细胞向促纤维化反应方向转变

Science Advances
IF12.5
2026-03-040
OA
Ximena L. Raffo-Iraolagoitia; Amanda J. McFarlane; Sarah Laing; Ryan Corbyn; Lindsey W. G. Arnott; Frédéric Fercoq; Lynn McGarry; Judith Secklehner; Marco De Donatis; John B. G. Mackey; Bjorn Kruspig; Robert Wiesheu; Ya-Ching Hsieh; Robin Shaw; Kai Rakovic; John Le Quesne; Graeme Clark; Colin Nixon; Crispin Miller; Kristina Kirschner; Calum C. Bain; Daniel J. Murphy; Seth B. Coffelt; Leo M. Carlin
Alveolar macrophages initiate the spatially targeted recruitment of neutrophils after nanoparticle inhalation

肺泡巨噬细胞在纳米颗粒吸入后启动空间靶向的嗜中性粒细胞募集。

Science Advances
IF12.5
2025-11-070
PRE
Qiongliang Liu; Lin Yang; Chenxi Li; Lianyong Han; Juliet Wilmot; Guo Yang; Riccardo Leinardi; Qiaoxia Zhou; Andreas Schröppel; David Kutschke; Judith Secklehner; Ali Önder Yldirim; François Huaux; Dagmar Zeuschner; Leo M. Carlin; Markus Sperandio; Otmar Schmid; Tobias Stoeger; Markus Rehberg
Epithelial cell-derived lumican modulates extracellular matrix dynamics in early-life airways disease

上皮细胞衍生的lumican调节早期生活气道疾病中的细胞外基质动力学

Journal of Allergy and Clinical Immunology
IF11.2
2025-09-170
OAAI
Franz Puttur; William J. Traves; Minerva G. Martin; Samuele Di Carmine; Frédéric Fercoq; David C.A. Gaboriau; Lewis J. Entwistle; Laura Yates; Régis Joulia; Sara Patti; Helen Stoelting; Ciara Campbell; Mindy L. Gore; Simone A. Walker; Lola E. Loewenthal; Philip L. Molyneaux; Leo M. Carlin; Sejal Saglani; Clare M. Lloyd
The eATP/P2x7R Axis Drives Quantum Dot-Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation

eATP/P2x7R轴驱动量子点纳米颗粒诱导的肺微循环中性粒细胞募集

ADVANCED SCIENCE
IF14.1
2024-10-040
OAAI
Li, Chenxi; Liu, Qiongliang; Han, Lianyong; Zhang, Haiyun; Immler, Roland; Rathkolb, Birgit; Secklehner, Judith; de Angelis, Martin Hrabe; Yildirim, Ali oender; Zeuschner, Dagmar; Nicke, Annette; Carlin, Leo M.; Sperandio, Markus; Stoeger, Tobias; Rehberg, Markus
Multimodal decoding of human liver regeneration

人肝再生的多模态解码

Nature
IF48.5
2024-05-010
OAAI
K. P. Matchett; J. R. Wilson-Kanamori; J. R. Portman; C. A. Kapourani; F. Fercoq; S. May; E. Zajdel; M. Beltran; E. F. Sutherland; J. B. G. Mackey; M. Brice; G. C. Wilson; S. J. Wallace; L. Kitto; N. T. Younger; R. Dobie; D. J. Mole; G. C. Oniscu; S. J. Wigmore; P. Ramachandran; C. A. Vallejos; N. O. Carragher; M. M. Saeidinejad; A. Quaglia; R. Jalan; K. J. Simpson; T. J. Kendall; J. A. Rule; W. M. Lee; M. Hoare; C. J. Weston; J. C. Marioni; S. A. Teichmann; T. G. Bird; L. M. Carlin; N. C. Henderson
Single cell RNA sequencing of human and murine cancers demonstrates metastases-specific neutrophil phenotypes driven by the IL-1β/CXCR2 signaling axis - Disruption of this pathway abrogates neutrophil immunosuppressive effects and reduces tumor burden
CANCER RESEARCH
IF16.6
2024-03-220
PRE
McLaren, Alistair S.; Fetit, Rana; White, Mark; Mills, Megan L.; Lannagan, Tamsin; Falconer, John; Cortes-Lavaud, Xabier; Gilroy, Kathryn; Ridgway, Rachel; Nixon, Colin; Naiker, Varushka; Njunge, Renee; Clarke, Cassie J.; Whyte, Declan; Kirschner, Kristina; Jackstadt, Rene; Norman, Jim C.; Carlin, Leo M.; Campbell, Andrew D.; Sansom, Owen J.; Steele, Colin W.
Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalization via macropinocytosis
NEURO-ONCOLOGY
IF13.4
2023-11-043
OAAI
Derby, Sarah J.; Dutton, Louise; Strathdee, Karen E.; Stevenson, Katrina; Koessinger, Anna; Jackson, Mark; Tian, Yuling; Yu, Wenxi; Mclay, Kathy; Misquitta, Josette; Alsharif, Sama; Clarke, Cassie J.; Gilmour, Lesley; Thomason, Peter; McGhee, Ewan; McGarrity-Cottrell, Connor L.; Vanderlinden, Aurelie; Collis, Spencer J.; Rominyi, Ola; Lemgruber, Leandro; Solecki, Gergely; Olson, Michael; Winkler, Frank; Carlin, Leo M.; Heiland, Dieter Henrik; Inman, Gareth J.; Chalmers, Anthony J.; Norman, Jim C.; Carruthers, Ross; Birch, Joanna L.
Lung extracellular matrix modulates KRT5+ basal cell activity in pulmonary fibrosis

肺细胞外基质调节肺纤维化中KRT5基底细胞活性

NATURE COMMUNICATIONS
IF15.7
2023-09-2712
OAAI
Hewitt, Richard J.; Puttur, Franz; Gaboriau, David C. A.; Fercoq, Frederic; Fresquet, Maryline; Traves, William J.; Yates, Laura L.; Walker, Simone A.; Molyneaux, Philip L.; Kemp, Samuel V.; Nicholson, Andrew G.; Rice, Alexandra; Roberts, Edward; Lennon, Rachel; Carlin, Leo M.; Byrne, Adam J.; Maher, Toby M.; Lloyd, Clare M.
The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair
SCIENCE IMMUNOLOGY
IF16.3
2021-11-2629
OAAI
McCowan, Jack; Fercoq, Frederic; Kirkwood, Phoebe M.; T'Jonck, Wouter; Hegarty, Lizi M.; Mawer, Connar M.; Cunningham, Richard; Mirchandani, Ananda S.; Hoy, Anna; Humphries, Duncan C.; Jones, Gareth-Rhys; Hansen, Carsten G.; Hirani, Nik; Jenkins, Stephen J.; Henri, Sandrine; Malissen, Bernard; Walmsley, Sarah R.; Dockrell, David H.; Saunders, Philippa T. K.; Carlin, Leo M.; Bain, Calum C.
Analysis of Prostate Cancer Tumor Microenvironment Identifies Reduced Stromal CD4 Effector T-cell Infiltration in Tumors with Pelvic Nodal Metastasis

前列腺癌肿瘤微环境分析确定盆腔淋巴结转移肿瘤间质CD4效应T细胞浸润减少

EUROPEAN UROLOGY OPEN SCIENCE
IF4.5
2021-07-018
OAAI
Ntala, Chara; Salji, Mark; Salmond, Jonathan; Officer, Leah; Teodosio, Ana Vieira; Blomme, Arnaud; McGhee, Ewan J.; Powley, Ian; Ahmad, Imran; Kruithof-de Julio, Marianna; Thalmann, George; Roberts, Ed; Goodyear, Carl S.; Jamaspishvili, Tamara; Berman, David M.; Carlin, Leo M.; Le Quesne, John; Leung, Hing Y.

研究方向

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F
Frédéric Fercoq
H 指数:13论文数:43被引数:834
C
Colin Nixon
H 指数:56论文数:400被引数:1.2万
D
Daniel M. Davis
H 指数:75论文数:413被引数:2.2万
J
John Le Quesne
H 指数:53论文数:244被引数:1.5万
J
Judith Secklehner
H 指数:5论文数:14被引数:246
K
Karen Blyth
H 指数:56论文数:413被引数:1.2万
E
Ewan J. McGhee
H 指数:30论文数:124被引数:4,628
T
Tony Ng
H 指数:55论文数:433被引数:1.1万
L
Lynn McGarry
H 指数:28论文数:161被引数:3,952
S
Simon Ameer‐Beg
H 指数:41论文数:174被引数:4,883